Name of Patient

F. S.

Age

35 y.o

Height

53

Diagnosis

G3P3 (3003) PU del. ceph. term live birth by 1oLSTCS +

BTL w/ variable deaceration; severe preeclampsia
M. M. Olmillo

Sex

Female

Weight

60 kg

Website

milkv.co.vu

A/N

youre welcome J

Author

DRUG DATA
Generic name:
Celecoxib

CLASSIFICATION
Pharmacologic:
Specific COX-2
enzyme inhibitor

Trade name/s:
Celebrex
Patients dose:
200 mg BID
Maximum dose:
400mg/day PO

Therapeutic:
Nonopioid analgesic

Pregnancy Category
Risk: D

MECHANISM OF
ACTION

Analgesic and antiinflammatory activities

related to inhibition of
the COX-2 enzyme,
which is activated in
inflammation to cause
the signs and
symptoms associated
with inflammation;
does not affect the
COX-1 enzyme, which
protects the lining of
the GI tract & has
blood clotting and
renal functions

Minimum dose:
50mg/day PO
Available forms:
Capsules 50,
100, 200, 400mg

Onset:
Slow, PO
Peak:
3 hrs, PO

Route:
PO

Duration:
unknown

INDICATIONS

General:
> acute & longterm treatment of
signs and
symptoms of
rheumatoid
arthritis &
osteoarthritis
> reductions of
the no. of
colorectal polyps
in FAP
> management of
acute pain
> treatment of
primary
dysmenorrhea
> relief or signs&
symptoms of
juvenile
rheumatoid
arthritis

CONTRAINDICATI
ON

Contraindicated with
allergies to
sulphonamides,
celecoxib, NSAIDs or
aspirin, significant renal
impairment;
perioperative pain post
CABG surgery;
pregnancy (third
trimester); lactation
Precaution:
Use cautiouslywith
impaired hearing,
hepatic, and CV
conditions

ADVERSE
EFFECTS

CNS: headache,
dizziness,
somnolence,
insomnia, fatigue,
tiredness, tinnitus,
ophthalmologic
effects

Dermatologic: rash,
pruritus, sweating,
dry mucous
membranes,
stomatitis
GI: nausea,
abdominal pain,
dyspepsia,
flatulence, GI
bleeding

Other:
Peripheral edema,
anaphylactoid
reactions to
anaphylactic shock

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

Before:
> check the doctors order
> wash hands before administration
>explain about the importance and
purpose of the drug to patient/SO
> assess skin color and lesions,
reflexes, sensations, edema, serum
electrolytes

CV: MI, CVA

Hematologic:
neutropenia,
eosinophilia,
leukopenia,
pancytopenia,
thrombocytopenia,
bone marrow
depression,
menorrhagia

Patients actual
indication:
celecoxib is
prescribed to
postpartum
mothers to relieve
and alleviate
acute pain

NURSING
RESPONSIBILITIE
S

Source: 2011
Lippincotts NDG

During:
> administer the right drug: recheck
the label
> administer drug with food or after
meals if GI upset occurs
> Establish safety measures if CNS
or visual disturbances occur
> arrange for periodic ophthalmologic
examination during long-term therapy
> take note for side effects

After:
> document and record.
> provide positioning and
environmental control to reduce pain
> provide warmth, positioning and
rest to reduce inflammation
> if overdose occurs, institute gastric
lavage, induction of emesis nd
supportive therapy
> monitor patients V/S.

Source: 2011 Lippincotts Nursing

Drug Guide