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one prospective), with the one by Bone et al.6 being most frequently cited. Bone et
al. reported that the incidence of pulmonary complications (adult respiratory
distress syndrome, pneumonia, and fat embolism) was higher and the stays in the
hospital and the intensive care unit were increased when femoral fixation was
delayed.
In 1990, Border reported on a comprehensive study of patients with blunt trauma
that challenged the accepted practice of immediate definitive fixation7. This
changed practice in the early 1990s, and a more selective approach to fracture
fixation was used; however, early fixation was still performed in most cases. During
the 1990s, more was learned about the parameters associated with adverse
outcomes in multiply injured patients and about the systemic inflammatory
response to trauma8. It became clear that fracture surgery, especially
intramedullary nailing, has systemic physiologic effects. These effects became
known as the second hit phenomenon.
The era of damage control orthopaedics started around 1993. Two reports from one
institution9,10described temporary external fixation of femoral shaft fractures in
severely injured patients. From 1989 to 1990, the frequency of using temporary
external fixation increased from <5% to >10%. The mean duration of external
fixation until intramedullary nailing was less than one week. Compared with patients
treated with immediate definitive fixation, those treated initially with external
fixation had more severe injuries, with higher injury severity scores and transfusion
requirements in the initial twenty-four hours. The term damage control began to
be used in the orthopaedic literature over the last six to seven years1,9-12.