ALAN RAY ROSENTHAL, PHARM.D.

Milwaukee, WI 53209
Home: (414) 228-9540

arrsnthl@aol.com

Fax: (414) 228-9540

SUMMARY
A proven leader in medical affairs:

Experienced medical affairs professional in all phases of product development - pre-launch to mature lifecycle management.

Field medical leadership supporting the delivery of scientific and therapeutic knowledge through quality
presentations and communications with thought leaders.

Strong record of interfacing science and business across geographies and business units in rapidly evolving
health care environment with demonstrated ability to deliver short term results with long term impact.

Dedicated to compliant integration of patient needs, health care professional interests, and payor concerns to
drive business results.

Extensive clinical practice, business and research experience bringing a fundamental understanding of the
unique aspects associated with pharmaceutical product development from the researcher's, clinician's,
patient's and sponsor's perspective.

Successful creation, implementation, management of Medical Affairs infrastructure, strategies and

operational initiatives for 4 organizations - over 10 yrs. management credentials - Medical Affairs, Business
owner (clinical trials) - VP Clinical Affairs (SMO).

University-level faculty teaching experience in a broad area of clinical pharmacology, pharmacy and
medicine.

Clinical expertise in immunology, respiratory, cardiovascular, metabolic, nephrology, hematology, critical

care medicine, infectious disease and CNS - psychiatric, pain management therapeutics.

Career Highlights

Industry medical affairs roles

Experienced Medical Science Liaison (7 MSL teams ) representing multiple product concepts covering
multiple geographic regions, ranging from 3-15 states, with advanced opinion leader engagements with
30-50 Key Thought Leaders

Leadership positions as Regional Director and National Program Manager for Field Medical
Affairs
Led 4 MSL teams (5-9 member teams) with responsibility for the development and implementation of
complete medical plans for 3 new start-up teams and 1 existing team
o Created and implemented Field Medical Affairs infrastructure, strategies and operational initiatives
for 3 Medical Affairs organizations
o Developed territories, KOL identification and tier analysis
o Developed and implemented of KOL engagement tracking platforms (TargetMobile / Veeva)
o Developed KOL interaction / engagement plans dialogue objectives, outcome analysis
o Developed Medical Intelligence reporting and tracking process

Medical/clinical trial industry experience

Established independent research practice that led to merger and successful transitioning into multicenter Site Management Organization (SMO)

Served as Principal Investigator in over 50 clinical trials

Designed, developed, recruited, trained- mentored staff and investigators

Established academic medical school clinical trials program

Assumed management of community based research center creating profitability within one year

Provided clinical research consulting services to SMOs & CROs

Coordinated project management & clinical trial monitoring / study site evaluation and start-up

PROFESSIONAL EXPERIENCE

HRC, Inc. (Health Research Consulting) Self-employed ownership,

1998 Current

Clinical research / medical affairs and clinical pharmacy consulting services. (Established in 1998 - operational at
various times between other full-time positions and in certain instances in conjunction with other positions with
permission and in compliance with non-competitive services)
- Clinical research / Medical affairs consulting services:
Medical affairs consulting services:
o Expert advice to clinical development and medical affairs leaders on their operational
infrastructure needs. Counsel and assistance with organization design, process improvement and
technology strategy
Services to SMOs and CROs, includes:
o Clinical research site management consulting services to physician practices, Site Management
Organizations (SMOs) to help develop and /or improve clinical site operations and financial
strength, CRO monitoring and site evaluation / study start-up services
- Clinical

pharmacy consultant providing pharmaceutical services to healthcare facilities

inVentiv Health, Somerset, NJ

July 2011 January 2015

Member of inVentiv Therapeutics Institute partnering with healthcare providers, practices, and associations to
raise awareness and educate patients to reach and maintain optimum health outcomes. Specifically supported
Medical Science Liaisons (MSLs) teams contracted to pharmaceutical industry
-

Member of inVentiv Health, The Therapeutics Institute management team

Managed start-up and operation (interview & hire of team of 5 to 7 members, program development and
implementation, integration between inVentiv Health and pharmaceutical client) for 3 national MSL teams
Provided direct MSL function for select regions, 3-5 states (WI,IL,OH,IN,MI)
Regional Director Iroko Pharmaceuticals (August 2013 December 2015)
Provided medical affairs support services for Iroko Pharmaceuticals under contract with inVentiv Health
(with focus on pain management - Zorvolex) Direct report to VP Medical Affairs at Iroko with Field
Medical Affairs administrative and team leadership responsibilities. Member of planning and
implementation team for US new product launch.
Regional Director Actavis Pharmaceuticals (February 2012 November 2012)
Provided medical affairs support services for Actavis under contract with inVentiv Health (with focus on
pain management - MoxDuo) -Working manager role that included providing MSL services and direct
KOL engagement for 4-state territory (OH, MI, IN, KY) in additional to internal medical affairs
administrative and team leadership responsibilities.
National Program Manager BioCritica, Inc. (July 2011 December 2011)
Provided medical affairs support services for BioCritica, Inc. under contract with inVentiv Health (with
focus on critical care, sepsis - Xigris) - Working manager role that included providing MSL services and
direct KOL engagement for 5-state territory (WI, IL, OH, IN, KY) in additional to internal medical affairs
administrative and field team leadership responsibilities.

Alan R. Rosenthal p2

Canyon Pharmaceuticals, Columbia, MD

April 2009 July 2010

Regional Medical Director

Member of start-up field medical affairs team for new product launch with focus on anticoagulation (VTE
prophylaxis & management), critical care, hematology, cardiology, cardio-vascular surgery:
Member of planning and implementation team for US new product launch
Developed and maintained KOL relationships for greater Midwest Western US territory
Provided pre-and post-launch presentations to health care and health care management providers
Participated in clinical trial site development / clinical trial support identified & initiated 8 clinical trial
sites (20% of total trial sites)
Provided medical communications support and development (medical letters, slide presentations, etc)

Bristol-Myers Squibb Company, Plainsboro, NJ,

August 2005 March 2009

Medical Science Liaison Immunoscience Division (March 2006 March 2009)

Represented abatacept (Orencia) with focus on rheumatologists treating patients with rheumatoid arthritis.
Executed new 3-state territory medical plan
Identified and developed over 40 key opinion leaders for long-vacant MSL territory
Established effective partnerships with matrix team to meet business plan goals
Developed several key opinion leader round table discussion groups incorporating BMS home office
Associate Director, Immunoscience to engage in advanced clinical / research discussions
Provided clinical presentations in conjunction with Health Care Management (HCM) Account Executives
for formulary review achieved advantageous tire level in several key accounts
-

Served as Regional Trainer - Immunoscience (East Region) March 2008 January 2009

Medical Science Liaison - Cardiovascular / Metabolic Division (August 2005 February 2006)
Represented clopidogrel (Plavix) with focus on cardiologists treating coronary artery disease, peripheral artery
disease and ibesartan (Avapro) with focus on cardiologists, nephrologists, treating patients for hypertension.
Assumed responsibility for vacated WI MSL territory
Established effective relationships with key opinion leaders in territory
Engaged in scientific exchange with healthcare providers
Supported collaboration with internal matrix team members to support business development objectives

BestMed, a Saatchi and Saatchi Company, New York, NY,

March 2004 July 2005

Provided MSL services to INO Therapeutics (now, Ikaria, Hampton, NJ) under contract with BestMed
representing inhaled nitric oxide (INO) with focus on pulmonology, cardiovascular, critical care, transplant,
neonatology HCPs and applications associated with pulmonary hypertension, COPD, acute lung injury, etc
Senior MSL

Established over 75 new KOL contacts in Midwest Region with development of 20+ key focused
relationships over 10 month period

Facilitated multiple CME programs

Developed KOL database designed to categorize and rate KOL relationships for MSL Team

Led team development of therapeutic presentation slide decks for INO applications

Provided CE presentations for selected venues on inhaled nitric oxides clinical applications
Field Manager

Successfully assumed managerial responsibility for 5-member MSL Team during period of staffing
turnover and transition.

Provided leadership for MSL Team with goal oriented, self-empowering management style.

Participated in interview and hire of two new MSLs and provided training and orientation

Established consistent reporting structure improving overall communication and team performance

Established initial set of MSL goals & objectives and key metrics

Provided leadership for transition of MSL Team from Marketing to Medical Affairs.

Participated in development of INOT MSL policies / position description / CME Grant Policy

Alan R. Rosenthal p3

HRC, Inc. (Health Research Consulting) (see above, page 2)

March 2002 March 2004

PharmaSeek, Milwaukee, WI

Feb 2001 March 2002

Director, Site Operations

Directed clinical research operations at PharmaSeek Clinical Trial Sites (Milwaukee Center for Clinical
Research) and assisted with new business development for sponsored clinical trials establishing first
profitable year for the research center.

Managed site operations, clinical trial budget analysis and contract negotiation, clinical trial support and
oversight, investigator support and liaison.

Medical College of Wisconsin,

Milwaukee, WI

August 1999 February 2001

Director, Clinical Trials Office (CTO)

Implemented and developed first centralized clinical trials center at MCW. Directed clinical research operations
and new business development for sponsored clinical trials. Managed site operations, clinical trial budget analysis
and contract negotiation, clinical trial support and oversight, investigator support and liaison providing clinical
trial support services for MCW physicians.

Hired core staff (administrative assistant, 2 CRAs) per Business Plan

Developed Marketing materials, CTO Brochure, marketing campaign for clinical trial opportunities

Successfully promoted CTO to MCW faculty and Departments

Fielded over 130 study contacts protocol review and feasibility analysis

Initiated / assisted with new venture opportunities

Over $2M CTO revenue generation potential (studies open, underdevelopment, under review)

HRC, Inc. (Health Research Consulting) (see above, page 2)

1998 - 1999

Health Advance Institute, Peoria, IL

1994 - 1998

(formerly, Peoria Medical Research Institute merged with Heartland Research Center)
Vice President, Clinical Operations
Managed clinical operations at Health Advance Clinical Research Centers. Reviewed protocols for feasibility and
profitability. Negotiated contracts and developed study budgets. Ensured timely completion of clinical trials
within budget guidelines. Supervised and trained site Research Directors and Managers. Participated in strategic
and business planning and assisted with marketing activities at local and corporate level. Maintained compliance
with GCP requirements and SOPs.

An original corporate officer and key member of the senior management team, grew business at the two
original sites (Peoria and South Bend) from start-up to over $1 million in revenue each over three year
period.

Managed work force of over 30 employees including middle management clinical research directors
with various responsibility for interviewing, hiring and annual reviews.

Established professional relationship with over 100 physicians and other health care professionals.

Led the design and build-out of two clinical research facilities each with over 6,000 sq.ft. encompassing
both clinical and administrative work areas.

Developed accounting and revenue recognition tools for budget management and staffing analysis.

Participated in venture capital business plan, site acquisition planning and transition of 10 newly
acquired sites into Health Advance organization

Alan R. Rosenthal p4

Heartland Research Center, Inc., South Bend, IN

October 1988 - June 1994

President/Clinical Director
The Heartland Research Center was a self-owned, privately held research organization formed to conduct clinical
drug studies primarily for the pharmaceutical industry on a contract basis.

Incorporated the services of over 50 community physicians and health care facilities comprising an
Investigator Network for the purpose of conducting clinical trials.

Grew this business from start-up to >$900,000 in revenue with 11 employees between 1988 and 1994.
Sold to Peoria Medical Research Institute in 1994.

Principal Investigator for over 50 clinical trials in multiple therapeutic areas, e.g. infectious disease,
gastroenterology (duodenal / GI ulcers, ulcerative colitis, irritable bowel syndrome), cardiovascular
(HTN, lipid disorders, CHF), metabolic (diabetes, renal disease), allergy & immunology
See Appendix for more detail.

Clinical Practice
1987 1988
1986 1987
1981 1986

1981 1983
1979 1980

1979 - 1988

Director, Clinical Affairs, Diroco, Inc. (hospital / pharmacy management organization)

IL/GA/TX/CA
Associate Director for Clinical Pharmacy Services Memorial Hospital of South Bend, IN
Clinical Coordinator, General Medicine Services, Cook County Hospital; Adjunct Assistant
Professor, College of Pharmacy, University of Illinois
Managed Adult Medicine Clinical Pharmacy Services consisting of 8 clinical pharmacists
Clinical practice 25 bed adult intensive unit (pharmacotherapy management)
Instructor Intensive Care Medicine Fellowship program
Consultant, Office of Program Evaluation and Research; Ohio Department of Mental Health
Director and Clinical Coordinator, Departments of Pharmacy and Pharmacology, Central
Ohio Psychiatric Hospital; Clinical Assistant Professor, College of Pharmacy, Ohio State
University

EDUCATION
PharmD, University of Tennessee, Center for the Health Sciences, Memphis, TN
BS, Pharmacy, University of Texas, Austin, TX

LICENSE
Texas (current) - 21069, Wisconsin (curent) - 13369-040, Illinois - 051-034166,

ADDITIONAL TRAINING

Practice Residency, Ben Taub Hospital, Hospital General, Houston, TX, ASHP Accredited

Clinical Pharmacy Residency, City of Memphis Hospital, University of Tennessee, Adult Internal Medicine,
Center for the Health Sciences, Memphis, TN

Clinical Pharmacology (Pharmacy) Practice Fellowship - Adult Internal Medicine, Duke University Medical
Center

Good Clinical Practice Guideline (GCP) training certification

Alan R. Rosenthal p5

ACADEMIC APPOINTMENTS & EDUCATIONAL ACTIVITIES

Assistant Professor of Pharmacology and Toxicology, Medical College of Wisconsin (1999-2001)

Adjunct Assistant Professor of Clinical Pharmacology, University of Illinois, College of Medicine at Peoria
(1995 to 1998)
Adjunct Assistant Professor of Pharmacy Practice, College of Pharmacy and Health Sciences. Butler
University (1996 to 1997)
Instructor, Medical Pharmacology, Indiana University, South Bend Center for Medical Education,
University of Notre Dame Campus, (September 1990 - 1992)
Adjunct Clinical Assistant Professor, College of Pharmacy. University of Illinois (1982-1988)
Instructor, Clinical Fellowship Training Program in Adult Critical Medicine, Critical Care Division, Cook
County Hospital (1982 - 1986)
Clinical Assistant Professor, College of Pharmacy, Ohio State University (1979 -1981)

PARTICIPATION IN GRANTS, COMMITTEES AND OTHER RESEARCH FUNDING

Member of Community Advisory Board and Curriculum Development Committee. "Interdisciplinary Health Care
for the Aged," a curriculum development project funded by HEW to the Colleges of Medicine and Pharmacy, and
School of Nursing at the Ohio State University, 1980 - 1982. Responsibilities included authorship of a module on
"Drug Therapy in the Elderly" for this training project.
Authored a grant proposal, "Development of a Pharmacokinetic Consultation Service and Clinical Pharmacy
Program in Mental Health" aimed at developing a project incorporate a pharmacokinetic laboratory and drug
therapy monitoring service with a program to train clinicians for primary and secondary care roles in mental health
practice 1980. The three-year funding proposal was for approximately $600K split between N.I.M.H., Ohio State
University & the Ohio Department of Mental Health.

PUBLICATIONS AND PRESENTATIONS:

Rosenthal AR, Martinez DR, Wood A: Rocky Mountain Spotted Fever, Voices 12/60 6: (June) 1977
Rosenthal AR, Self TH, Baker ED, Linden RA: Interaction of Isoniazid and Warfarin, Journal American Medical
Association 238:2177 (Nov. 14) 1977.
"Valporic Acid", a monograph in Duke University Medical Center Guide to Anticonvulsant Drugs.
Rosenthal AR, Martinez DR, Morrison JC: Rational and Irrational Antibiotic Use in Hospitalized OB-GYN
Patients: A Preliminary Report. (Presented at the ASHP Clinical Meeting 1977)
Baker ED, Martinez DR, Rosenthal AR: Integration of Drug Information Retrieval Skills and Clinical Clerkship
Activities: Comparison of Programmed Instruction and Faculty Instruction. (Presented at AACP Meeting in
Seattle, 1977).
Sharps-Chen J, Rosenthal AR, McLeod DC: Models and Manpower Projections for Clinical Psychiatric
Pharmacy Practice in Ohio. (Presented at Ohio Department of Mental Health Research Grant Review Meeting,
1979).
Rosenthal AR: Overview of Pharmacokinetic and Therapeutic Drug Monitoring in Psychiatry and the Role of
Clinical Pharmacy. Teaching Module for Geriatric Curriculum OSU School of Pharmacy
Rosenthal AR: Drug Therapy in the Elderly: Pharmacokinetic Principles Dosage Adjustment and Patient
Monitoring. (Educational Module for "Interdisciplinary Health Care for the Aged" training grant, Ohio State
University, (see under "Participation in Grants").
Rosenthal AR: Cost-benefit Analysis of Clinical Pharmacy Services. (Presented at ACCP Meeting in Orlando,
July, 1985).
Tricyclic and "Second Generation" Antidepressants in the Treatment of Affective Illness. (lecturer on Ciba
Speaker's Bureau - 1984-1986).
Beta Blockers and Treatment of Hypertension (Lecturer on Sandoz Speaker's Bureau - 1983-1985).
Therapy of Hyperlipidemia. (Lecturer on Speaker's Bureau - Warner-Lambert/Parke-Davis - 1989-1991).
Krichbaum DK & Rosenthal A: Contract Clinical Research: A Rapidly Changing Marketplace. J Pharmacy
Practice 6:406-415 December 1996.

Alan R. Rosenthal p6

PRESENTATIONS AND SEMINARS BY INVITATION

Invited Speaker, CBIs 6th Annual Defining Appropriate and Effective Interactions with Thoughts Leaders and
Key Opinion Leaders (KOLs) KOL Program Development 101 - A Primer for Small and Mid-Sized
Pharmaceutical, Medical Device and Biotech Companies. Presentation & Workshop on: (a) Opinion Leader
Identification & (b) Defining and Measuring Outcomes. Princeton, NJ. - November 9-10, 2009
Invited Speaker, Advanced Management Skills for a Successful Clinical Trials Center - Full day workshop, ACRP
Annual Meeting, Toronto, CA, April 2002.
Invited Speaker Using Metrics to Manage a Research Site Developing a Dynamic Business Plan ACRP
Annual Meeting San Francisco April 2001.
Session Chair and Speaker Will Your Growth and Success Put You Out of Business Tools for Financial
Management and Planning for Growth DIA Annual Meeting San Diego, June 2000.
Panel Speaker - Budget and Contact Negotiation - Issues from the Investigative Sites Perspective - DIA Annual
Meeting, Boston, June 1998.
Workshop Moderator and Speaker - Resource Management and Staff Allocation at the Clinical Site ACRP Annual Meeting, Atlanta, 1997.
Upjohn Speaker, Fluvoxamine - Obsessive Compulsive Disorder, 1994
Faculty Presenter, Dirithromycin in the Treatment of Bronchitis - Review of Research, Dirithromycin US
Investigator's Meeting, August 19-21, 1994.
Panel Moderator, Justify Economic Value of Clinical Pharmacy Services, American College Clinical Pharmacy
Annual Meeting, July, 1988
Efficacy of Transdermal Nitroglycerin in Coronary Artery Disease. Cardiology Conference, Medical City Dallas
Hospital, April, 1986.
Drug Therapy in the Elderly. DuPage Pharmacist Organization, January, 1986.
The Use of Vasodilators in the Treatment of Congestive Heart Failure and Post Myocardial Infarction. Grand
Rounds - Critical Care Lecture Series, Cook County Hospital, February, 1983
Tricyclic vs. Second Generation Anti-depressants in the Treatment of Affective Illness. Illinois Council of
Hospital Pharmacists Annual Meeting, 1982.
Pathophysiology and Treatment of Gram-negative Bacteremia and Shock, Medical College of South Carolina,
College of Pharmacy, 1979; University of Oklahoma, College of Pharmacy, 1979.
An Objective Drug Usage Study Surveying the Rational and Irrational Use of Antimicrobial Agents. Texas
Society of Hospital Pharmacists. Annual Meeting, 1975.

PROFESSIONAL ORGANIZATIONS
Society of Critical Care Medicine (SCCM)
American College of Clinical Pharmacology
American Society of Clinical Pharmacology and Therapeutics (ASCPT)
American College of Clinical Pharmacy (ACCP)

BOARDS AND COMMITTEES:

Reviewer for J Clin Res Pharmacoepidemiol - 1992-1993
ACP Publications Committee - 1993
ACCP Industrial Relations Committee - 1992-1994
ACCP Industrial Relations Committee (Chairman) - 1995
Board of Directors - Epilepsy Foundation, South Bend, IN 1996
Board of Directors American Lung Association Northern Indiana (1995-1999)
ACRP Finance Committee (Chairman) - 1996-1999
Candidate for Treasurer - ACRP 1998
Chairman, Academic Medical Centers Forum, ACRP 2000 2001
Chairman, Site Managers Forum, ACRP 2001- 2003

Alan R. Rosenthal p7