Calculating Dosages

Several formulas can be used to calculate drug dosages.

1. One formula uses ratios:

Dose on hand_ = desired dose______

Quantity on hand quantity desired (x)

For example, erythromycin 500 mg is ordered. It is supplied in a liquid form containing

250 mg in 5 mL. To calculate the dosage, use the formula:

Dose on hand (250)_ = desired dose_(500 mg)_____

Quantity on hand (5 mL) quantity desired (x)

Then, cross multiply:

250 x = 5 mL x 500 mg
x = 5 mL x 500 mg
250 mg

x = 10 mg

Therefore, the dose ordered is 10 mL.

2. Another method for dosage calculation is:

Amount to administer (x) = desired dose________________

Dose on hand x quantity on hand

For example, heparin can be distributed in large vials and prepared dilutions of 10,000
units per mL. If the order calls for 5000 units, the nurse can calculate using the above
formula:

x = 5000 x 1
10000

x = 1 mL
2

Therefore the nurse injects 0.5 mL for a 5000 unit dose.

Source: Berman, A & Snyder, S. (2004). Clinical Handbook for Fundamentals of

Nursing: Concepts, Procedures and Practice, 7e. Upper Saddle River, NJ: Prentice Hall.
pg. 217-219.
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