Professional Documents
Culture Documents
Published for the dental professional community by the American Association of Endodontists
Summer 2006
Welcome to ENDODONTICS: Colleagues for Excellencethe newsletter covering the latest in endodontic treatment,
research and technology. We hope you enjoy our coverage on the full scope of options available for patients through endodontic
treatment and that you find this information valuable in your practice. All issues of this ENDODONTICS newsletter are available on
the AAE Web site at www.aae.org, and cover a range of topics on the art and science in endodontic treatment.
100
90%
80%
70%
91
96
89
85
60%
Percentage
50%
40%
45
30%
20%
10%
0%
Penicillin VK
Amoxicillin
Amoxicillinclavulanate
Clindamycin
Clarithromycin
Metronidazole
Conclusion
The use of improved culturing and molecular methods
now detect the presence of many more organisms in
endodontic infections than previously determined. It
is important that clinicians understand the nature of
polymicrobial endodontic infections and realize the
importance of removing the reservoir of infection
by endodontic treatment or tooth extraction. The
prescription of antibiotics should be considered
adjunctive to the clinical treatment of the patient;
antibiotics should not be substituted for root
canal debridement and drainage of purulence
from a periradicular swelling.
References
1. Baumgartner JC, Hutter JW, Siqueira JF. Endodontic Microbiology and Treatment of Infections. In: Cohen S, Hargreaves KM, editors.
Pathways of the Pulp. Ninth ed. St. Louis: Mosby; 2006.
2. Fouad AF, Rivera EM, Walton RE. Penicillin as a supplement in resolving the localized acute apical abscess. Oral Surg 1996;81(5):590595.
3. Henry M, Reader A, Beck M. Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth. J
Endodon 2001;27(2):117-123.
4. Nagle D, Reader A, Beck M, Weaver J. Effect of systemic penicillin on pain in untreated irreversible pulpitis. Oral Surg Oral Med Oral
Pathol Oral Radiol Endod 2000;90:636-40.
5. Pickenpaugh L, Reader A, Beck M, Meyers WJ, Peterson LJ. Effect of Prophylactic amoxicillin on endodontic flare-up in asymptomatic,
necrotic teeth. J Endodon 2001;27(1):53-56.
6. Walton RE, Chiappinelli J. Prophylactic penicillin: effect on posttreatment symptoms following root canal treatment of asymptomatic
periapical pathosis. J Endodon 1993;19(9):466-470.
7. Jaimes EC. Lincocinamides and the incidence of antibiotic-associated colitis. Clin Therapeu 1991;13(2):270-280.
8. Baumgartner JC, Xia T. Antibiotic susceptibility of bacteria associated with endodontic abscesses. J Endodon 2003;29(1):44-47.
9. Khemaleelakul S, Baumgartner JC, Pruksakorn S. Identification of bacteria in acute endodontic infections and their antimicrobial
susceptibility. Oral Surg Oral Med Oral Pathol 2002;94(6):746-55.
10. Pallasch TJ. Pharmacokinetic principles of antimicrobial therapy. Periodontol 2000 1996;10:5-111.
11. ADA. Antibiotic prophylaxis for dental patients with total joint replacements. JADA 2003;134(July):895-899.
12. Dajani AS, et al. Prevention of bacterial endocarditis: Recommendations by the American Heart Association. JAMA
1997;277(22):1794-1801.
13. Gilmore WC, Jacobus NV, Gorbach SL, Doku HC. A prospective double-blind evaluation of penicillin versus clindamycin in the
treatment of odontogenic infections. J Oral Maxillofac Surg 1988;46:1065-1070.
Did you enjoy this issue of ENDODONTICS? Did the information have a positive impact on your practice?
Are there topics you would like ENDODONTICS to cover in the future? We want to hear from you!
Send your comments and questions to the American Association of Endodontists at the address below.