Medical Science Catalogue

THE NEUTROPHILS: NEW OUTLOOK FOR
OLD CELLS
RECENT ADVANCES IN PSORIASIS: THE

ROLE OF THE IMMUNE SYSTEM
edited by Dmitry I Gabrilovich (Vanderbilt University)
by Barbara S Baker (Imperial College School of Medicine,

St. Marys, London)
This invaluable volume, written by group of internationally established scientists,

present an overview of the most recent findings on the biology of neutrophils.
These cells have become a focus of attention in recent years because of their
fascinating biochemistry and molecular biology and their ability to affect the
function of other cells. The book describes, in detail, the molecular events
leading to neutrophil activation, migration, microbial killing, production of
oxidative radicals and cytokines, and eventually to the death of these cells.
It presents new information that has never been discussed in monographs
before. It also gives a unique overview of the neutrophils role in viral diseases,
including Aids. Finally, the book describes how to improve the function of
neutrophils and use these cells in the treatment of diseases.
This book presents the evidence for the belief that psoriasis is a disease
of abnormal keratinocyte proliferation induced by T cells. The latest
approaches to investigating the immunopathogenesis of this disease,
and a review of previous findings, are presented to give an overall
picture of the current knowledge in this field. Each topic is discussed
in detail, clearly illustrated and well referenced. The book should prove
invaluable to clinical dermatologists, and researchers in the fields of
immunology and dermatology who have an interest in skin diseases.
Contents: Clinical and Histological Features of Psoriasis; Skin Immune
System in Psoriasis; Immune Cell Function in Psoriasis; Psoriasis is a
T Cell-Mediated Disease; b-Haemolytic Streptococci and Psoriasis;
Immune Function of Psoriatic Keratinocytes; Current and Future
Immunological Approaches to Treatment of Psoriasis; Model for the
Pathogenesis of Psoriasis.
Contents: Molecular Events in the Activation of Neutrophils; Oxidative Burst

in Neutrophils. New Insight; Mechanism of the Neutrophil Migration and
Accumulation in Tissue. Role in Reperfusion Injury; Regulation of Neutrophil
Function by Cytokines and Fatty Acids; Production of Cytokines by
Polymorphonuclear Neutrophils; Chemokines and Their Role in Leukocyte
Function. New Outlook; Neutrophils and Apoptosis; Diagnostic Evaluation of
Neutrophil Function; Neutrophils in Viral Infections; Colony-Stimulating Factors
in Therapy of Neutrophil-Related Problems; Granulocyte Infusion Therapy.
180pp (approx.)
1-86094-120-6
Readership: Postgraduate students in immunology, biochemistry and cell/

molecular biology.
Published by Imperial College Press and distributed by World

Scientific Publishing Co.
280pp (approx.)
1-86094-082-X
Readership: Researchers in immunology and dermatology.
Pub. date: Autumn 1998

US$58 40
World Scientific Series in 20th Century Biology Vol. 4
Published by Imperial College Press and distributed by World Scientific

Publishing Co.
HEPATITIS B AND THE PREVENTION

OF CANCER OF THE LIVER
Selected Publications of Baruch S Blumberg
edited by Barach S Blumberg (Fox Chase Cancer Center, USA)
HED
PUBLIS
This important book comprises a narrative account of research on the

hepatitis B virus (and related subjects) and selected reprints from the
laboratory of Nobel laureate Baruch S Blumberg and his colleagues.
The Hepatitis B virus (HBV) is one of the ten most common deadly
infectious diseases and is responsible for 1.1 million deaths a year
worldwide.
MOLECULAR BIOLOGY OF HUMAN

HEPATITIS VIRUSES
by J Monjardino (Imperial College School of Medicine, St. Marys
Campus)
Research in his laboratory resulted in the discovery of HBV and the

invention of the vaccine which protects one against it. The research
began as an apparently esoteric study of human biochemical and
immunologic variation. This required field-work in Africa, the Arctic,
the Pacific, the Americas, and in many other locations and populations.
The overall goal was to identify inherited biological differences which
were related to differing responses to disease-causing agents. The virus
was discovered using the blood of an infected person who had developed
the antibody, to detect the virus present in another infected person
who had become a carrier of the virus. Screening of blood donors
led to the near-elimination of post-transfusion hepatitis B.
Hepatitis A and B viruses have infected nearly half

the current world population, and as many as 500
million people are still infected with the hepatitis
B or C virus today. Hepatitis B vaccination is
effective but not universally adopted and no vaccine
is available against Hepatitis C. Treatment is
prohibitively expensive for areas of high endemicity
or prevalence and not universally effective.
This important and timely book covers recent
advances in understanding the molecular biology
of hepatitis viruses. The advances have contributed
new insights into the molecular mechanisms involved in replication of genetic
information and in gene expression, and have translated into diagnostics,
prevention and development of antiviral drugs.
There are now national HBV vaccination programs in more than 70

countries. During the past decade these programs have strikingly reduced
the prevalence of HBV in many countries and there has been a
significant drop in the incidence of cancer of the liver in the vaccinated
cohorts. The HBV vaccination program is now, after smoking cessation,
the most widely used cancer prevention program in the world.
Contents: Hepatitis A Virus; Hepatitis B Virus; Hepatitis Delta Virus; Hepatitis

C Virus; Hepatitis E Virus; Other Hepatitis-Associated Viruses: HGV/GBC.
Readership: Students in human biology and researchers in virology,

vaccinology, genetics, anthropology, history & sociology of science,
public health and the scientific method.
Readership: Virologists (medical/non-medical) and molecular biologists.
148pp
1-86094-048-X
Pub. date: Spring 1999

US$28 19
Pub. date: Jun 1998

US$24 16
600pp (approx.)
981-02-3217-9

Publishing Co.
Medical Science

US$92 64
World Scientific Publishing
FORTHCOMING
I mmunology
I mmunology
HEPATITIS B VIRUS
FORTHCOMING
Molecular Mechanisms in Disease and Novel Strategies for

Therapy
edited by Rajen Koshy (Department of Virology, Royal
Postgraduate Medical School, UK) & Wolfgang H Caselmann
(Department of General Internal Medicine, University of Bonn,
Germany)
The Science and Culture Series Medicine
CHRONIC PANCREATITIS
Erice, Italy
14 15 October 1996
edited by Eugene P DiMagno (Mayo Clinic & Mayo Foundation) & Alberto Maringhini (University of Palermo, Italy)
The book covers both the molecular

aspects of Hepatitis B virus replication and
gene expression in vivo and in model
systems, and the clinical impact of genetic
variants or immunological response in
chronic infection. Major emphasis is laid
on the molecular mechanisms underlying
Hepatitis B virus-associated liver carcinogenesis and their possible relevance to
therapy and to the prevention of infection.
Rational approaches to design novel
vaccines or cytokine treatments, as well as strategies to develop
vectors for liver-directed gene therapy, are discussed.
This volume focuses on novel developments in our basic understanding

of the anatomy, molecular biology and cell biology of the normal
human pancreas and the mechanisms underlying changes in chronic
pancreatitis. It also explores new data from epidemiological studies
regarding risk factors, the natural history and outcome of patients with
disease, and mechanisms underlying pain and malabsorption derived
from animal studies. Finally, it discusses how these novel data are
leading to improved medical (including application of gene transfer
technology) and surgical treatment of chronic pancreatitis.
Contents: Anatomy and Pathology; Molecular and Cell Biology of
the Pancreas; Epidemiology and Natural History of Chronic Pancreatitis;
Experimental Models of Chronic Pancreatitis; Pathophysiology of
Chronic Pancreatitis; Diagnosis of Chronic Pancreatitis; Treatment of
Chronic Pancreatitis.
Contents: Molecular Biology of Hepatitis B Virus: Replication of the

Hepatitis B Virus Genome (C Seeger & W S Mason); The Regulation of
Hepatitis B Virus Gene Expression: An Overview of the Cis- and TransActing Components (M J Kosovsky et al.); Animal Models and Experimental
Systems in Hepatitis B Virus Research (S Schaefer et al.); Infection and
Chronic Disease: Natural Course of HBV Infection (H E Blum et al.);
Genetic Variants of HBV (T J Harrison); The Immunology of Chronic
Hepatitis B (B Rehemann & F Chisari); Hepatocellular Carcinoma: HBV
DNA Integration and Insertional Mutagenesis (K Koike); Transactivators
of HBV, Signal Transduction and Tumorigenesis (W H Caselmann &
R Koshy) ; Oncogenes, Tumour Suppressors, and Co-Factors in
Hepatocellular Carcinoma (H Nagai & M A Buendia) ; Rational
Approaches for the Prevention of Infection and Therapy: Hepatitis B
Virus Vaccines (F Schdel); Chronic Hepatitis B Viral Infection: Cytokines
and Therapy (G R Foster & H C Thomas); The Development of
Targettable Vectors for the Liver and Prospects for Treatment (L Weiss
& P H Hofschneider).
Readership: Molecular & cell biologists and general practitioners.
600pp (approx.)
981-02-3440-6
World Scientific Series in 20th Century Biology Vol. 2
A PORTRAIT OF THE IMMUNE SYSTEM

Scientific Publications of N K Jerne
edited by Ivan Lefkovits (Basel Inst. for Immunology, Switzerland)
Using the published work of Nobel Laureate Niels Kaj
Jerne, this book shows how he developd his ideas. The
book is a compilation of his published work, but in fact
it is much more than that. Whether the reader wants
to read the book systematically, or only browse, it opens
a fascinating world of hypotheses, theories, facts and
vistas. His selection theory, his view of how immunological
diversity is created, and his concept of lymphocytes
interacting as a network, reveals Jernes revolutionary
spirit. The book ought to be a rich source of inspiration
for everyone interested in science and how science is
made.
Readership: Molecular biologists, immunologists and microbiologists.
340pp
1-86094-007-2

US$110 76
Pub. date: Jul 1998

US$58 40
Published by Imperial College Press and distributed by World

Scientific Publishing Co.
Contents: Preface: The Master and His Atelier (G Stent); Overview: A Portrait of
the Immune System (I Lefkovits); On the Writing of a Paper with N K Jerne by
Antonio et al.; Bibliography; Facsimiles of Selected Publications: A Study of Avidity
Based on Rabbit Skin Responses to Diphtheria Toxin-Antioxin Mixtures (N K Jerne);
The Natural-Selection Theory of Antibody Formation (N K Jerne); Immunological
Speculations (N K Jerne); Plaque Formation in Agar by Single Antibody-Producing
Cells (N K Jerne & A A Nordin); The Natural Selection Theory of Antibody Formation;
Ten Years Later, in: Phage and the Origins of Molecular Biology (N K Jerne); The
Somatic Generation of Immune Recognition (N K Jerne); The Immune System
(N K Jerne); Towards a Network Theory of the Immune System (N K Jerne); Idiotypic
Networks and Other Preconceived Ideas (N K Jerne); The Generative Grammar of
the Immune System (N K Jerne); and other papers; Introductions to the BII Annual
Reports; Handwritten Letters; Postscript (I Lefkovits).
Readership: Biological scientists, immunologists and medical doctors.
896pp
981-02-2605-5
981-02-2614-4(pbk)
Medical Science
Pub. date: Dec 1996

US$139 96
US$68 47
H aematology
O phthalmology
SELF-ASSESSMENT FOR THE MRCP:

HAEMATOLOGY
FORTHCOMING
HIV AND THE EYE
by Barbara Jane Bain (Imperial College School of Medicine, St.

Marys Hospital)
edited by Susan Lightman (Moorfields Eye Hospital, UK)

This book covers comprehensively the eye problems associated with HIV
infection, in both their diagnosis and their management. It is aimed at all doctors
involved in the care of HIV patients, and is well illustrated. There is a chapter
on the current management of HIV-infected patients, and the rest of the book
deals with the types of ocular problems. Diagnosis, differential diagnosis and
management are all covered in detail.
This invaluable book has been written specifically

for trainee physicians preparing for the second part
examination for membership of the Royal College
of Physicians. It is in the format of this examination
and the questions are typical of those used. The
questions have been selected to cover sections of
haematology which are particularly important for
specialists in internal medicine. Although the
questions have been formatted for this specific
examination, the book will also be useful for those
preparing for similar examinations in other countries
and, in addition, will be helpful to those preparing for examinations of the
Royal College of Pathologists. The text is well illustrated with clinical photographs
and photomicrographs.
Contents: Current Management Approaches in HIV (S Ash); HIV Infection and

Pre-AIDS Ocular Phenomenon (P McCluskey); HIV, AIDS, Types of Ocular
Phenomenon (D Jabs); External Eye Disease in HIV (A Tullo); CMV Retinitis
(B Dhillon); Other Causes of Retinitis (A Hall); Neuro-Ophthalmic Problems
in HIV & AIDS (E Graham); Surgery in AIDS Patients (A Tufail & S Schwartz);
AIDS and the Eye in Developing Countries (P Kestelyn).
Readership: Doctors involved in the care of HIV patients, and ophthalmologists.
300pp (approx.)
1-86094-084-6
The author has had many years experience in the postgraduate education
of trainee physicians, haematologists and pathologists, and has written several
authoritative textbooks in the fields of haematology and haematopathology.

Publishing Co.
Readership: Students preparing for examinations for college physicians,

pathologists and haematologists.
136pp
1-86094-068-4
Pub. date: Apr 1998

US$28 19
COLOUR ATLAS OF OPHTHALMOLOGY

3rd Edition
by Arthur S M Lim (Singapore National Eye Center) & Ian J Constable
(Lions Eye Institute, Australia)

Publishing Co.
Once in a long while a specialist writes a

textbook which even a general practitioner
can get excited about. Such a book is the
new Colour Atlas of Ophthalmology ... True
to its title, this is an atlas of ophthalmology
and the colour reproduction of the pictures
is absolutely top rate.
Journal of the Royal College of General
Practitioner, England
SCIENCE IS NOT A QUIET LIFE

Unravelling the Atomic Mechanism of Haemoglobin
by Max Perutz (MRC Lab. for Molecular Bio., England)
Linus Pauling called haemoglobin the most
interesting and important of molecules. This
important volume shows how X-ray crystallography
was used to determine its bewilderingly complex
atomic structure and to unravel the stereochemical
mechanisms of its respiratory functions. It introduces
isomorphous replacement with heavy atoms which
led to the first protein structures, haemoglobin and
its simpler relative myoglobin. Later papers deal
with the stereochemistry of the cooperative effects
of haemoglobin, with the relationships between
the structures and impaired functions of abnormal
haemoglobin, with species adaptation of haemoglobin, and with its action as
a drug receptor and as an oxygen sensor. The final papers deal with amino
acid repeats which act as polar zippers and their role in certain inherited
neurodegenerative diseases.
This book is lavishly illustrated entirely with

high quality colour photographs ... The
colours are rendered accurately, and the diagnosis of common eye
conditions simply becomes a matter of matching the patient to the
photograph.
The Australian & New Zealand Journal of Surgery
There is an excellent distribution of external and fundus photographs,
most of high quality ... a fine, brief atlas and text that deals with
ophthalmologic disease on a practical level.
American Journal of Ophthalmology
Although the authors have kept the volume small and handy with
brief text, the presentation is practical and will be useful as a quick
source of reference to students of medicine, ophthalmology and
optometry and also family physicians and practising optometrists.
British Journal of Optometry & Dispensing, 1998
Contents: Diffraction Without Tears: A Pictorial Introduction to X-Ray Analysis

of Crystal Structures; Early Studies; Solution of the Phase Problem; From the
First Molecular Model to the Allosteric Mechanism; The Haemoglobin Battles;
Molecular Pathology of Human Haemoglobin; Haemoglobin as a Drug Receptor;
Species Adaptations in Haemoglobin; Early Shots at the Folding and Unfolding
Problems; Present Work: Polar Zippers and Neurodegenerative Disease;
Haemoglobin as an Oxygen Sensor that Regulates Expression of Nitrogenase
Genes; Glaciers.
Contents: Examination; Lid, Lacrimal Apparatus and Orbit; Conjunctiva, Sclera

and Cornea; Lens and Glaucoma; Uveal Tract, Retina and Vitreous; Ocular
Manifestations of Systemic Diseases; Neuro-Ophthalmology; Eye Diseases in
Children; Ocular Injuries; Refractive Errors; Ophthalmic Drugs; Index.
Readership: Biochemists, chemists, medical researchers and molecular biologists.
660pp
981-02-2774-4
981-02-3057-5(pbk)
Pub. date: Jan 1998

US$78 54
US$29 19.85
Readership: Medical students and medical practitioners.
116pp
981-02-2286-6
981-02-2339-0(pbk)
Jointly published by Imperial College Press and World Scientific Publishing Co.
Medical Science

US$58 40
Pub. date: Aug 1995

US$38 28
US$25 18
O phthalmology
VISION FOR THE WORLD
A TEXTBOOK OF CLINICAL
OPHTHALMOLOGY, 2nd Edition
Eye Surgeons Solution to Mass Blindness

A Major World Medical Problem
by Arthur S M Lim (Spore Natl Eye Ctr.)
A Practical Guide to Disorders of the Eyes and Their Management

by Ronald Pitts Crick (Kings College Hospital, London) &
Peng Tee Khaw (Moorfields Eye Hospital, London)
Contents: Introduction; Impact of Technology on

Mass Blindness in Asia; Increasing Importance of
Eye Surgeons in Mass Cataract Blindness A
Megatrend; Tianjin Centre Training of Surgeons;
Quality Assurance in Cataract Surgery; Towards
Perfect Outcome; Low Cost Implant Techniques;
Quality Cataract Surgery in Asia in the Year 2000; Interview with Professor
Arthur Lim On Mass Cataract Blindness.
A concise, well illustrated comprehensive

book of ophthalmology which reads easily
and well ... Many of the illustrations are in
colour and clearly portray the clinical conditions described. Outstanding value for
money.
Annals of the Royal College of Surgeons
of England
Readership: Ophthalmologists, hospital administrators, health economists,

epidemiologists, medical institutions and general medical practitioners.
Clinical Ophthalmology would make an

excellent text for students, junior doctors and
GPs who wish to develop an interest in ophthalmology and gain greater
proficiency than is offered by shorter texts.
Eyenews
Oct/Nov 1997
96pp
981-02-2848-1
981-02-2508-3(pbk)
This comprehensive textbook, an excellent new edition A practical

guide to disorders of the eyes and their management, the text will
be especially useful to medical, ophthalmology and optometry students
and also general medical practitioners and practising optometrists.
British Journal of Optometry & Dispensing, 1997
Series on Information Display Vol. 2
VISION MODELS FOR TARGET DETECTION

AND RECOGNITION
In Memory of Arthur Menendez
edited by E Peli (The Schepens Eye Res. Inst., Harvard Medical
School)
This is a very nice little textbook which is small enough to fit easily
into a briefcase. While not attempting to be fully comprehensive, it
does cover all aspects of ophthalmology with particular attention to
the most common problems seen in practice and also gives a flavour
of some of the rarer conditions It is well illustrated not only with
colour and black and white plates but also with a series of very good
simple line drawings which show clearly the principles of common
surgical procedures.
Eye, 1998
The book is organized into three general sections. The first covers basic
modeling of central (foveal) vision and its theoretical background. The second
is centered on the evaluation of model performance in applications, while
the third is dedicated to aspects of peripheral vision modeling and the expansion
of peripheral modeling to include visual search.
Readership: Scientists, engineers, and systems designers interested in the
integration of modern vision science into the design and evaluation of human
performance with novel display and sensor technologies.
Contents: Basic Studies: Practical Anatomy and Physiology of the Eye and Orbit;
Formation of the Eye; Optics and Refraction; Common Ophthalmic Problems:
Simple Methods of Eye Examination; Painless Impairment of Vision (In the White
Eye); Painful Impairment of Vision (In the Red Eye); Red Sticky Eyes (Conjunctivitis);
Watering Eyes; Dry Eyes; Squinting Eyes (Strabismus) Disorders of Ocular
Motility; Examination of the Eyes: Examination of Structure; Examination of
Function; Systemic Ophthalmology: Cardiovascular Conditions; Blood Diseases;
Endocrine Diseases; Infections and Infestations; Nutritional Deficiencies; Systemic
Immune Disorders (Collagen Diseases); Neurology; Congenital Abnormalities
and Genetic Disorders Functional Disorders; Regional Ophthalmology: Eyelids;
Lacrimal Apparatus; Conjunctiva; Cornea and Sclera; Lens; Vitreous; Uvea;
Retina; Orbit; Disorders Associated with the Level of Intraocular Pressure;
Therapeutics and Iatrogenic Disorders: Therapeutics Part 1 and 2; Iatrogenic
Disorders.
432pp
981-02-2149-5
Pub. date: May 1995

US$73 51
GLAUCOMA SURGERY
2nd Edition
by Maurice H Luntz & Raymond Harrison (Manhattan Eye, Ear &
Throat Hospital)
Contents: Congenital, Infantile and Juvenile Glaucoma: Emergence of a Disease
Entity; Congenital, Infantile and Juvenile (CIJ) Glaucoma; Clinical Manifestations;
Management of CIJ Glaucoma and the Prognosis for Surgery; Adult Onset
Glaucomas: Preoperative Preparation and Anesthesia for Glaucoma Surgery;
Selection of Surgical Procedure; Angle Closure Glaucoma; Surgery for Primary
and Secondary Open Angle and Chronic Closed Angle Glaucoma; Glaucoma
and Cataract; Management of Secondary Glaucoma; Alloplastic Devices in
Glaucoma Surgery: Setons; Complications Following Filtration Surgery and their
Management; Laser Surgery; References; Index.
Readership: Ophthalmologists, graduate students and ophthalmologists-intraining.
616pp
981-02-2262-9
981-02-2373-0(pbk)
Pub. date: Jun 1996

US$38 26
US$18 12
Pub. date: May 1997

US$99 72
US$48 35
Readership: Ophthalmologists.
232pp
981-02-1418-9
Pub. date: Jul 1994

US$99 69
Co-published by World Scientific Co. Pte Ltd and P G Publishing.
Medical Science
O rthopaedics
CERVICAL SPONDYLOSIS AND SIMILAR
DISORDERS
ADVANCES IN TISSUE BANKING Vol. 2

by G O Phillips (The North Wales & Oswestry Tissue Bank, UK),
D M Strong (Puget Sound Blood Center/Northwest Tissue Center,
USA), R von Versen (German Institute for Cell & Tissue Replacement,
Germany) & A Nather (National University Hospital Bone Bank,
Singapore)
edited by E J Dunn (University of Massachusetts Medical Center),

J Dvork (Schulthess Klinik, Switzerland) & K Ono (Osaka
University Medical School)
With rapid advances in medical technology and
progress in medicine during the last 27 years,
severe disability or sustained neck-shoulder-arm
pain secondary to cervical spondylosis can be
detected much earlier. Excellent or good results
of surgery can be achieved compared to the past,
due mainly to advances in diagnostic imaging and
surgical procedure.
This volume of tissue banking is the second of a

series extending the interdisciplinary field. All of
the authors of this book have been major
contributors of scientific and medical publications
in their respective specialities. There are articles
covering blood transfusion; bone marrow and stem
cell transplantation; immunology and the role of
immunology in musculoskeletal transplantation,
various aspects of cryopreservation of organs,
cartilage and tendons; organ perfusion preservation;
the history and long term follow-up of osteochondral
allografts, both frozen and fresh; neurosurgical applications; cardiovascular
applications; the use of skin and newer biological membranes for wound
coverage.
Through research into cervical spondylotic

myelopathy, particularly the conditions combined
with a narrow spinal canal, orthopaedic surgeons
in Japan have revealed the key mechanism involved in myelopathy and the
specific manifestation leading to early recognition of the affliction, the myelopathy
hand, and have invented a canal-expansive laminoplasty. Extensive
decompression of the impinged spinal cord with remarkable ill effects such
as instability or adhesion was accomplished for the first time. Further study
has been ongoing to clarify the pathomechanism of Spondylosis through
biomechanical and animal model studies.
The book is of particular importance, in that it has been written in memory

of Kenneth W Sell, MD, PhD, a pioneer and promulgator of tissue banking
and transplantation. Many of the physicians, surgeons and scientists who trained
under his leadership have gone on to distinguish themselves in the various
aspects of transplantation. Many of them have contributed to this book,
exemplifying the diversity of Dr Sells contributions to tissue banking and
transplantation.
This volume consists of contributions by experts worldwide on the recent

advances in the study of cervical spondylosis and will serve as a valuable
reference for all researchers, surgeons and postgraduate students.
Contents: The Contribution of Kenneth W Sell to the Progress of Tissue Banking;

Progress in Blood Transfusion and Marrow Transplantation; Immunological
Developments in Support of Orthopaedic Surgery; Cryopreservation of Organs
and Tissue; Osseous and Osteochondral Transplantation; The Contribution of
Tissue Banking in Cardiovascular Surgery and Neurosurgery; Banking and
Clinical Use of Human Skin, Biological Membranes and Acellular Dermis.
Contents: Introduction; Epidemiology, International Comparison; Anatomy;

Biomechanics of the Cervical Spine and Development of Spondylosis; Animal
Model of Spondylosis; Pathology; Pathophysiology of Compressive Myelopathy;
Symptomatology; Radiology Including MRI; Electrophysiological Diagnosis;
Diagnosis; Non-Surgical Treatment; Surgical Treatment; Prognosis; Premature
Cervical Spondylosis in CP; Cervical Spondylosis and Trauma; Ossification of
the Posterior Longitudinal Ligament (OPLL).
Readership: Neurosurgeons, orthopaedic surgeons and researchers in
biomechanics and bioengineering.
Readership: Orthopaedic surgeons, general surgeons, neurosurgeons,

cardiologists, transplant surgeons, cryobiologists, health regulators, tissue bankers,
burn specialists and students.
784pp
981-02-2744-2
384pp
981-02-3534-8
Pub. date: Sept 1998

US$128 85

US$78 52
ADVANCES IN TISSUE BANKING Vol. 1

by G O Phillips (The North Wales & Oswestry Tissue Bank, UK), R von Versen (German Inst. for Cell & Tissue
Replacement, Germany), D M Strong (Puget Sound Blood Ctr., USA) & A Nather (Natl Univ. Hospital Bone Bank, Singapore)
Contents: Regulatory Models for the Safety
and Quality of Allografts: Europe; United States
of America (Heart Valves); Transplant Donation
Coordination: Experience in the United
Kingdom: Tissue Donor Referral and Selection;
The Spanish Model: Keys to Procurement
Transplant Procurement Management (TPM);
Allografts in Orthopaedics: The Osteoinductive
Properties of Demineralised Bone Matrix Grafts;
Bone Substitutes and Related Materials in
Clinical Orthopaedics; The Use of Allograft
Versus Mega-Prostheses in Children; The Influence of Bone Cemented
Massive Allografts on Postoperative Complications; Frozen Allograft for
Acetabular Bone Defects in Revision Total Hip Replacement (THR); Clinical
Results and Organisational Aspects of Autogeneous and Allogenous Bone
Grafting in the Treatment of 226 Patients with Primary Osseous Neoplasms;
Systemic Application of Growth Hormone (GH) increases Serum Bone
Medical Science
Turnover Markers in Distraction Osteogenesis of Micropigs; Use of Massive

Bone Allografts at the Femoral Side in Revision Hip Arthroplasty; Foetal
Membranes and Cultured Keratinocytes: Utilisation of Foetal Membranes
on the Treatment of Burns and Other Skin Defects; Autogenous Serum
for Culturing Keratinocyte Autografts; Heart Valve Banking: Heart Valve
Banking; Cell and Tissue Preservation: Principles of Cryopreservation;
Principles of Freeze Drying; Optimisation of Cryopreservation of Subfertile
Semen Samples. A Computer-Assisted Study; Sterilisation: Sterilisation of
Tissue Allografts; Radiation Sterilisation of Allografts in Kitasato University
Bone Bank (KUBB).
Readership: Orthopaedic surgeons, general surgeons, cardiologists,
transplantologists, cryobiologists, National Health regulators and tissue
bankers.
340pp
981-02-3190-3
Pub. date: Oct 1997

US$68 47
O rthopaedics
HED
LIS
PUB
MICROSURGERY IN ORTHOPAEDIC
PRACTICE
OSTEOPOROSIS IN ASIA
CROSSING THE FRONTIERS
by P C Leung (Chinese Univ., HK), Y D Gu (Shanghai Medical

Univ.), Y Ikuta (Hiroshima Univ.), A Narakas (Lausanne),
A Landi (Modena Univ.) & A J Weiland (Johns Hopkins Univ.)
Editor-in-Chief: E M C Lau (The Chinese Univ. of Hong Kong)

Co-editors: S C Ho, S Leung & J Woo (The Chinese Univ. of
Hong Kong)
The importance of microsurgery in orthopaedic

surgery is expected to increase rapidly. This
volume is therefore a valuable reference for
practising junior as well as senior orthopaedic
surgeons. It contains an updated and practical
survey of the topics discussed. It is full of new
ideas, some of which may not be orthodox.
Contents: The Epidemiology of Osteoporosis

in Asia (E M C Lau); Epidemiological Studies
of Osteoporosis in Japan (S Fujiwara); Bone
Acquisition in Children and Adolescents (S
S F Leung et al.); Attainment of Peak Bone
Mass and Dietary Factors in Chinese Women
(S C Ho); Dietary Calcium and Bone Density
of Women in China (J F Hu et al.); Osteoporosis
in Korea (I K Han & N H Cho); The Menopause
and Osteoporosis (C J Haines); Biochemical
Aspects of Osteoporosis (J Woo et al.); Vitamin
D in the Treatment of Osteoporosis (T Fujita); Genetic Factors for
Osteoporosis (R P Young); Research in Osteoporosis: Looking into the
Future (P C Leung).
Contents: Basic Concepts; Microsurgery for

Hand Reconstruction; Microsurgery for the
Spine; Microsurgery for the Hip Region;
Microsurgery for Reconstruction after Tumour
Resection (P C Leung); Replantation Surgery (Y-D Gu); Muscle Graft
(Y Ikuta); Brachial Plexus Lesions (A O Narakas); Peripheral Nerve Injuries
(A Landi et al.); Microsurgery in Lower Limb Trauma (M J Yaremchuk
& A J Weiland).
Readership: Postgraduate students in internal medicine, epidemiology &

orthopaedics and researchers in osteoporosis & molecular and
cell biology.
Readership: General surgeons, orthopaedic surgeons, hand and plastic

surgeons.
364pp
9971-50-860-5
192pp
Pub. date: Dec 1997
981-02-2730-2
US$48 33
Pub. date: Feb 1995

US$65 45
FORTHCOMING
FORTHCOMING
MICROSURGERY FORUM
BRACHIAL PLEXUS PALSY
edited by P C Leung (The Chinese University of Hong Kong)
by H Kawai (Hoshigaoka Koseinenkin Hospital, Osaka) &

H Kawabata (Osaka Medical Center & Res. Inst. for Maternal &
Child Health, Osaka)
Microsurgery is an important surgical technique that is applicable to many fields

of surgery in general. The contributions given by surgeons in China and other
Chinese speaking surgeons in the area of microsurgery have been important and
plentiful. This volume represents the highlights of a seminar held in 1994 in
Hongkong. Participants included prominent Chinese speaking clinicians active
in the field of microsurgery. The purpose of the seminar was to sort out the
current concepts and the state-of-the-art of this surgical field.
This book is a monograph about brachial plexus palsy. Severe brachial plexus
injuries are often caused by traffic accidents, especially motorcycle accidents.
The intercostal nerve transfer to the musculocutaneous nerve is a standard
treatment of choice in Japan to reconstruct elbow flexion for brachial plexus
palsy with root avulsion. The functional conversion of the nerve transfer
is described in detail, using electrophysiological and histochemical studies.
This book focuses on birth-related brachial plexus palsy as well as the
treatment of brachial plexus injuries in adults.
Contents: Development of Basic Research in Microsurgery (S P Chow); Replantation

of Severed Limbs and Digits (Z W Chen); Microsurgical Reconstruction of the
Hand Using Toe and Toe-Tissues (F C Wei); Vascularized Joint Transfers (T M
Tsai); Anatomical Basis of Skin Pedicle and Bone Pedicle (S Z Zhang); FascioCutaneous and Myocutaneous Free Flaps (K C Hui); Vascularized Bone Crafts
(P C Leung); Peripheral Nerve Microsurgery (J K Zhu); Brachial Plexus Injuries
(Y D Gu).
Readership: Surgeons and clinicians.
Contents: Brachial Plexus Injury in Adults: Anatomy of the Brachial Plexus;

Historical Review of the Brachial Plexus Surgery; Closed Traction Injury of
the Brachial Plexus; Clinical Assessment of the Brachial Plexus Lesion; Nerve
Surgery of the Brachial Plexus; Intercostal Nerve Transfer; Pain Management
of the Brachial Plexus Lesion; Reconstructive Musculoskeletal Surgery of the
Paralyzed Limb; Brachial Plexus Birth Palsy: Perinatal Factors; Natural History;
Treatment: Rehabilitation; Neurosurgery; Musculoskeletal Surgery.
250pp (approx.)
981-02-2616-0
Readership: Orthopaedic surgeons, plastic surgeons, neurosurgeons, physical

therapists and occupational therapists.
Pub. date: Summer 1999

US$58 40
250pp (approx.)
981-02-3139-3
Medical Science

US$48 33
O rthopaedics
LUMBAR SPINE DISORDERS
FORTHCOMING
Current Concepts
Volume 2
edited by R M Aspden & R W Porter (Univ. Aberdeen)
BONE MICROCIRCULATION
by I McCarthy (Imperial College School of Medicine)
This book emphasises the unique organisation of the microcirculation in bone,
and shows the importance of blood flow and vascular pressures in the normal
physiology of bone. Techniques for the physiological measurement of bone
circulation in both clinical and experimental situations are described. In addition,
the book discusses the clinical significance of disorders of bone circulation
and describes the response of the microcirculation to injury and its role in
fracture repair.
Contents: Epidemiology of Low Back Pain: The

British Contribution (P R Croft) ; Measuring
Health Outcomes in Low Back Pain (A Garratt &
D Ruta); Pain Sources in the Lumbar Spine (R C
Mulholland); Characterisation of the Innervation to
the Intervertebral Discs and Associated Ligaments
(P W McCarthy); The Role of the Blood Supply
in Lumbar Spine Disorders (I L H Reichert et al.);
Pathology of Symptomatic Lumbar Disc Protrusion: Medico-Legal and Surgical Implications
(R W Porter); Magnetic Resonance Imaging of the
Lumbar Spine (P Thorpe & F W Smith); Digital Videofluoroscopy and
Abnormal Spinal Movement (A C Breen & R Allen); Radionuclide Bone Scanning
(F W Smith & P Thorpe); Spondylolisthesis (J R Johnson); Ankylosing Spondylitis
(A C Ross & M Dolman); Isolated Disc Resorption (H Crock & S Matsuda);
Posterior Lumbar Interbody Fusion and Cages (M R K Karpinski); Clinical Trial
to Investigate Stabilisation of the Spine (J C T Fairbank et al.); Management
of Spinal Stenosis (J E Nixon); Epidural Injections in the Management of Low
Back Pain and Sciatica (K Bush).
Contents: Anatomy of the Vasculature in Bone; Measurement of Bone Blood

Flow; Vascular Reactivity of Bone; Transcapillary Exchange; Interactions of the
Vascular System and Bone; Vascular Response to Fracture; Bone Microcirculation
in Pathological Conditions.
Readership: Orthopaedic surgeons and bone physiologists.
300pp (approx.)
1-86094-070-6

Publishing Co.
RECENT ADVANCES IN UPPER EXTREMITY

ARTHROPLASTY
Readership: Clinicians and researchers in orthopaedics and rheumatology.
216pp
981-02-2792-2

US$48 33
Pub. date: Nov 1996

US$58 40
Proceedings of the Brussels International Upper Extremity Symposium

Brussels, Belgium
28 29 April 1995
edited by F Schuind (Erasme Univ. Hospital, Belgium) & K N An
(Mayo Clinic/Mayo Foundation, USA)
While joint replacements at the lower extremity,
particularly at the hip and knee, are performed on
a daily basis in most departments of Orthopaedics,
with great clinical success and long longetivity of
the implant, the indications are much less frequent
at the upper limb. Basic research follows the same
tendency: while there are numerous basic or clinical
research projects devoted to the hip or knee, very
scarce reports are published on upper extremity
joint replacements.
LUMBAR SPINE DISORDERS: CURRENT

CONCEPTS
The aims of publishing this volume are to promote

the exchange of ideas, and to forster collaborative investigations among clinicians,
manufacturers, engineers and other basic scientists involved with the problems
of replacement arthroplasty in upper extremity joints, from the finger to the
shoulder. The specific aims are: (1) to summarize scientific knowledge in the
area of upper extremity joint replacement; (2) to discuss currently unsolved
clinical problems and potential solutions based on current scientific knowledge;
(3) to review new prosthetic designs; and (4) to explore future directions of
investigation.
(Volume 1)
edited by R M Aspden & R W Porter(Univ. Aberdeen)
This book draws together recent results and ideas from most of the leading
UK researchers into back pain. The emphasis is on disorders of the lumbar
spine, their pathogenesis, diagnosis and treatment. This is in contrast to most
books on the spine which either concentrate on the normal spine or deal with
a specialised approach such as surgery. By drawing together contributions from
a wide range of clinical and scientific backgrounds, including alternative
therapies such as osteopathy and chiropractice, the problem of low back pain
is shown to be complex and multifactorial.
Contents: Small Joint Arthroplasty of the Hand: A Short History (R L Linscheid);

Upper Extremity Arthroplasty: Indications, Contraindications, Patient Selection
(F Schuind & F Burny); Finger Joint Replacement: A Challenge for the Next
Century (G R Sennwald et al.); DJOA Arthroplasty Ten Years of Experience,
and Introducing the DJOA 3 (J-L Condamine et al.); The Palmar Approach
in Flexible Implant Resection Arthroplasty of the Proximal Interphalangeal
Joint (D B Herren & B R Simmen); GUEPAR Total Trapeziometacarpal
Arthroplasty (J-Y Alnot); Biomechanics of the Wrist: Multidisciplinary Approach
(P Ledoux et al.); Arthrodesis of the Wrist: Back to the Future? (R Lemaire
& J-J Rombouts); Neer Shoulder Prosthesis: Results Related to the Etiology
(P Boileau & G Walch); The Use of Osteochondral Allografts in the Upper
Limb (C Delloye); and other papers.
Contents: The Curved, Flexible Spine and the Functions of Ligaments and
Muscles (R M Aspden); Biomechanics of the Intervertebral Disc Disc Pressure
Measurements and Significance (D S McNally); Neuropeptides in the Lumbar
Spine (I K Ashton & S M Eisenstein); Growth and Development of the Lumbar
Vertebral Canal (R W Porter); Measurement of Vertebral Blood Flow and Its
Significance in Disc Disease (A M C Thomas et al.); The Role of Vascular
Damage in the Development of Nerve Root Problems (M I V Jayson & A J
Freemont); Fear-Avoidance: The Natural History of Back Pain and Its Management
(J D G Troup & P D Slade); Costs and Effectiveness: Approaches to the
Management of Back Pain (J A K Moffett & G Richardson); and other papers.
Readership: Clinicians and researchers in orthopaedics and rheumatology.
Readership: Orthopedic surgeons, plastic & reconstructive surgeons and

researchers in biomechanics & bioengineering.
260pp
981-02-2175-4
376pp
981-02-2699-3
Pub. date: Feb 1995

US$55 38
Medical Science
Pub. date: Mar 1997

US$79 55
B iomechanics
DISLOCATION BASED
FRACTURE MECHANICS
Advanced Series in Biomechanics Vol. 1
SELECTED WORKS ON BIOMECHANICS

AND AEROELASTICITY
by Johannes Weertman (Northwestern Univ.)
(In 2 Parts)
by Yuan-Cheng Bertram Fung (UC, San Diego)
This book is a compendium of papers contributed by Y C Fung,
Chairman of the World Council for Biomechanics, on the
development of biomechanics in the past 30 years. Most of the
articles are records of original contributions scattered in many
journals. Having these papers collected together, classified according
to subjects, and arranged in chronological order for each subject, will
help the reader to obtain a total perspective of his work and his
association with his colleagues. The selection ranges from constitutive
equations, microcirculation, heart, lung, blood vessels, ureter and
other internal organs, and tissue engineering. Several summary articles
provide a fascinating guide to the evolution of ideas over this period
of time. His work done in the field of aeroelasticity predates his
biomechanics work. The applications of some general ideas of aeroelasticity are broader than
the specific topics discussed, as exemplified by the sharing of ideas between aeronautics and
biology.
This valuable title will be of interest to anyone concerned with bioengineering and aeronautics,
and should have a place in the library of people who are just starting their career as well as
those who are well into it.
Readership: Bioengineers, cardiologists and orthopaedic surgeons.
2008pp
Pub. date: Aug 1997
981-02-2063-4(set)
US$190
138
BONE STRUCTURE AND REMODELING

Proceedings of the Symposium held at the Second World Congress of Biomechanics
Amsterdam
10 15 July 1994
edited by A Odgaard (Orthopaedic Hospital, Denmark), & H Weinans (University
of Nijmegen, The Netherlands & RushPresbyterianSt. Lukes Medical Center,
Chicago, USA)
... this book captures much of the current research activity and debate about bones
putative ability to adapt to mechanical loading. It would be an excellent reader for
a graduate seminar or a course in bone physiology and mechanics, and it is a good
reference for the bookshelves of those directly or indirectly engaged in this field of
research.
R Bruce Martin
J. Biomechanics, 1996
The contained information is a compendium of topics authored by leading investigators
who represent the current and present focus of opinion, research and interest in the
field. It also contains information of interest and value to students and researchers
in the field of bone dynamics. The book would be a valuable addition to any biomedical
library and to most departments, groups or individuals active in the field of bone
structure and remodeling.
J Wilson
V.C.O.T., 1996
This volume aims at bringing together investigators from a number of sub-fields to attempt an
integrative approach. Thus, the mechanical aspects of bone are studied by anatomists, biologists,
clinicians and engineers. In each case, individual investigators usually have some knowledge of
the other fields, but disciplinary allegiances mean that it is remarkably difficult to get them all
together in one group. The process of diffusion across disciplines represented in this volume will
strengthen and hopefully be the start of the development of a coherent theory concerning bone
structure and remodelling. The chapters include theoretical, mechanical, architectural and experimental
approaches. They especially attempt to elucidate the complexities involved in the different
methodologies and the interactions amongst the different disciplines.
This is an excellent scholarly work which fills a tremendous need for such a
book. It is so well-written
that it can serve as a textbook, reference material,
and valuable historical
document ... This reviewer
wholeheartedly recommends Dislocation Based
Fracture Mechanics for
purchase by students, researchers, scholars, scientists, geologists, geophysicists, glaciologists, and
engineers particularly in the areas of civil, structural,
foundation, transportation, mechanical, electrical,
metallurgical, agricultural, and aeronautical engineering, who need a good understanding of the
subject of fracture mechanics in order to solve
practical field problems associated with crack initiation, propagation, and prevention. Every library
should also purchase copies of this superb book.
Appl. Mech. Rev., 1996
The dislocation is the basic building block of the crack
in an elastic-plastic solid. Fracture mechanics is developed
in this text from its dislocation foundation. It is the only
text to do so. It is written for the graduate student and the
new investigator entering the fracture field as well as the
experienced scientist who has not used the dislocation
approach. The dislocation mechanics needed to find the
dislocation density fields of crack tip plastic zones is
developed in detail. All known dislocation based solutions
are given for the three types of cracks in elastic-plastic solids
are given.
Contents: Griffith-Inglis Crack and Zener-Stroh-Koehler
Crack; Dislocation Mechanics; Hilbert Transforms and
Muskhelishvili Equations; Bilby-Cottrell-Swinden-Dugdale
(BCSD) Crack; Crack Tip Shielding and Antishielding by
Dislocations; Mode III Crack in an Elastic-Plastic Solid;
Mode II Crack in an Elastic-Plastic Solid; Mode I Crack
in an Elastic-Plastic Solid; Moving Yoffe Crack; Interesting
Applications; Appendices: Short Table of Hilbert Transforms;
Table of Useful Integrals for Crack Problems; Stress Fields
of Dislocations Near or On an Interface; Table of Useful
Equations; Derivation of the Del Gradient and Other
Operators for the Shifting Center Cylindrical Coordinate
System; Orthogonal Curvilinear Coordinates; Dislocations
in Stress Space; References; Index.
Readership: Scientists and graduate students in materials
science and theoretical & applied mechanics; and students
and graduate students in geophysics.
548pp
981-02-2620-9
Pub. date: Feb 1996

US$68 48
Readership: Researchers with a general interest in bone from the fields of biomechanics, anatomy,
orthopaedics and biology.
268pp
Pub. date: Apr 1995
981-02-2190-8
US$89
62
Medical Science
C ardiology
Cardiopulmonary Medicine Series
FORTHCOMING
CONTROVERSIES IN THE DESCRIPTION OF

CONGENITALLY MALFORMED HEARTS
ECHOCARDIOGRAPHY IN CONGENITAL
HEART DISEASE MADE SIMPLE
by Robert H Anderson (Imperial College School of Medicine) &

Anton E Becker (Univ. Amsterdam)
by S Y Ho, A N Redington, M L Rigby & R H Anderson (Imperial

College)
This series of four video tapes, which is based on

the demonstrations pre-recorded by Robert H
Anderson and Anton E Becker, two prominent
European morphologists, shows the essence of the
abnormal morphology within carefully selected
autopsy specimens, comparing the findings with
appropriately dissected normal hearts, and
supplementing the anatomic material with
diagrams and cartoons. Accompanying these tapes
is an explanatory book prepared with extensive
full colour illustrations based on the specimens
and diagrams used in the videos and supplemented by appropriate material
from the extensive files of the authors.
Video and Chapter Titles:
Atrioventricular septal defects
Hearts with isomeric atrial appendages
Tetralogy of Fallot and double outlet right ventricle
Hearts with univentricular atrioventricular connection
Congenital malformations of the heart are often dismissed as a form of complex

heart disease, which is too difficult to understand, and is best referred to
the specialists. The authors of this handbook, however, aim to dispel this
myth. The advent of cross-sectional and, more recently, three-dimensional
echocardiography, enables the structural malformations to be visualised virtually
non-invasively. Without a thorough understanding of the arrangement of cardiac
structures, interpretation of these images can be very frustrating, not to mention
having to cope with difficult terminology. Contrary to popular belief, however,
the reader does not require a knowledge of cardiac embryology in order to
understand the morphology of a malformed heart.
This book takes the reader through the subject in a straightforward fashion,
beginning with recognition of the normal cardiac chambers, progressing through
the process of analysing the layout of the chambers in a sequential way, and
then dealing with the more common cardiac defects in turn. Each chapter
deals with the anatomical arrangement illustrated with diagrams and
complemented with echocardiographic images of the most important crosssections. The text is succinct, and is accompanied by numerous diagrams and
cross-sectional echocardiographic images of the highest quality. The most
common defects are described chapter by chapter, emphasising the salient
anatomical features.
Readership: Pediatric cardiologists, pediatric cardiac surgeons, pathologists,

intensivists and imagers.
Readership: Cardiologists, cardiac surgeons, cardiovascular pathologists and

echocardiographers.
150pp (approx.)
1-86094-124-9
212pp
book only
1-86094-067-6

US$48 33
Pub. date: Apr 1998

US$75
48
book + 4 video tapes (PAL or NTSC)

1-86094-067-6 + 1-86094-118-4 (PAL)
1-86094-067-6 + 1-86094-119-2 (NTSC)

Publishing Co.
US$320
US$320
200
200

Publishing Co.
FORTHCOMING
THE CONDUCTION SYSTEM OF THE

MAMMALIAN HEART
FORTHCOMING
An Anatomico-histological Study of the Atrioventricular Bundle

and the Purkinje Fibers
by S Tawara
Translators: Kozo Suma (Tokyo Womens Medical University, Japan)
& Munehiro Shimada (National Leprosarium Tama-Zenshoen, Japan)
Series on Echocardiographic Diagnosis of Congenital Heart Disease
ECHOMORPHOLOGIC CORRELATES: THE

NORMAL HEART
by R H Anderson, S Y Ho & A N Redington (Imperial College)
Sunao Tawaras epoch-making work on the excitation conduction system of

the mammalian heart paved the way for the advancement of modern cardiology
in the 20th century. Even today, more than 90 years after the publication of
the German monograph Das Reizleitungssystem des Sugetierherzen, his
precise account of the conduction system from the atrioventricular node through
the HisPurkinje system to the ordinary ventricular muscle fibers retains all
of its original actuality.
This video is the first in a series which will introduce the viewer to a philosophic
approach for, and a morphologic background to, the diagnosis of children with
congenitally malformed hearts. In each video we demonstrate the anatomy
as seen in echocardiographic cuts, relating to the three-dimensional structure
of the heart and then show the echocardiographic images themselves,
demonstrating the window from which they have been obtained. The first video
is the essential introduction to normality, showing the orthogonal planes of
the heart relative to the body, and illustrates how the echocardiographer
interrogates each plane. Emphasis is then placed on normal anatomic features
which underscore sequential segmental analysis. The video is the first of its
kind and is accompanied by an explanatory booklet containing video time
codes to guide the viewer.
This English edition of Tawaras monograph will serve as an invaluable reference

for both basic and clinical cardiological research in the years ahead.
Contents: History; Results of the Study; Critical Conclusive Considerations;
Summary of the Results; Instruction Regarding the Method by Which to Cut
the Atrioventricular Bundle in Animal Experiments.
Readership: Cardiologists, cardiac surgeons, physiologists, anatomists and
biologists.
250pp (approx.)
1-86094-116-8
Readership: Paediatric cardiologists, physicians, medical students and researchers.

US$48 35
32pp (approx.)
1-86094-110-9

Publishing Co.
Medical Science

US$140 95

Publishing Co.
10
C ardiology
ELECTROCARDIOLOGY 96:
FROM THE CELL TO THE BODY SURFACE
FORTHCOMING
ELECTROCARDIOLOGY 98
Proceedings of the XXIII International Congress on Electrocardiology

Cleveland, Ohio
31 July 4 August 1996
edited by J Liebman (Case Western Reserve Univ.)
Proceedings of the XXV International Congress on

Electrocardiology
Budapest, Hungary
3 6 June 1998
edited by Istvn Prda (Hayhal Imre University of Health Sciences,
Budapest, Hungary)
Contents: Measuring and Modeling Electrical Activity from the Cardiac Cavities
to the Body Surface (B Taccardi et al.); The Forward Problem: From Myocardial
Activation to Epicardial Potentials (P Colli Franzone et al.); The Forward
Problem: From Heart Models to Body Surface Potentials (R Gulrajani); The
Inverse Problem: Reconstructing Pericardial Potentials from Body Surface
Potentials (A Van Oosterom & G Huiskamp); Appropriate Electrode Placement
in Evaluating Varied Cardiac Pathology (F Kornreich et al.); Ionic Processes
Underlying the Action Potential (C Antzelevitch et al.); Early Afterdepolarizations:
Mechanisms and Possible Role in Arrhythmias (C January & Z Zhou); Focal
Activity: Mechanisms and Possible Role in Arrhythmias (R Joyner); and other
papers.
The analysis of electric signals of the heart is one of the most fundamental
and informative research and clinical tools of cardiology and internal medicine.
This book covers the latest developments in the field of electrocardiology. It
will be useful for every physician and cardiologist.
Contents: Rijlant Memorial Lecture (R H S Selvester); Computer Application
in the ECG Evaluation The Model of Repolarization (K Harumi); The Power
of the Spatial Covariance of Pericardial Potentials (A van Oosterom); Simulated
P Wave Surface Potential Distributions During Retrograde Atrial Activation:
Locating Concealed Kent Accessory Pathways (R M Gulrajani et al.); A Coupled
Torso and Myocardium Simulator Using the Luorudy Cell Model
Implementation and Results (G T Lines et al.); Rate-Independent Prolongation
of Cardiac Action Potentials by Thiamine Derivative, Thiamine Tetrahydrofurfuryl
Disulfide (M Kanno et al.); Interactions of Pimobendan and Isoproterenol in
Ginea-Pig Isolated Ventricular Myocytes (Y C Chen et al.); Diagnosing Myocardial
Infarction Using Statistical Analysis of Digital Electrocardiographic Data (R A
Warner & N E Hill); Effects of Antiarrhytmic Drugs on the Monophasic Action
Potential and the Ventricular Evoked Response (B Merkely et al.); and other
papers.
Readership: Cardiologists and paediatricians.
708pp
981-02-3109-1
V ascular Surgery
Readership: Cardiologists.
420pp (approx.)
981-02-3670-0
Pub. date: Jul 1997

US$124 86
FORTHCOMING
Pub date: Autumn 1998

US$88 60
THE VENOUS CLINIC

Diagnosis, Prevention, Investigations, Conservative and
Medical Treatment, Sclerotherapy and Surgery
by G Belcaro (Chieti University, Italy & St. Marys Medical
School, London), A N Nicolaides (St. Marys Medical
School, London) & G Stansby (Imperial College, London)
Venous diseases are among the most
commonly encountered problems at
primary care level, yet they are poorly
understood and often mismanaged. This
concise, highly illustrated book will fill
the need of all primary care staff and
trainees for clear information on the
diagnosis and management of the different
conditions and their complications.
ELECTROCARDIOLOGY 97
Proceedings of the XXIV International Congress on Electrocardiology
Bratislava, Slovak Republic
24 28 June 1997
edited by Ljuba Bacharova (Institute for Heart Research, Slovak
Academy of Sciences) & Peter W Macfarlane (University of Glasgow)
Contents: Basic Electrophysiology and Electropharmacology; Heart Rate Regulation and
Rhythm Disturbances; Body Surface Potential
Mapping; Computer Assisted Electrocardiography;
Clinical Electrocardiography, Vectorcardiography,
and Dipolar Electrocardiotopography; Electrocardiologic Monitoring of Myocardial Rejection;
Standards for Core ECG Laboratories.
Contents: The Venous System; Diagnostic

Tests in Venous Insufficiency; Superficial
Venous Insufficiency and Varicose Veins; Superficial Thrombophlebitis;
Subclavian and Axillary Venous Thrombosis (SAVT); Chronic Venous
Insufficiency and Postphlebitic Syndrome; Chronic Limb Swelling;
Lymphatics and Lymphoedema; Deep Venous Thrombosis; Pulmonary
Thromboembolism; Prevention of Venous Thromboembolism;
Varicocoele; The Pelvic Congestion Syndrome and Vulvar Varices;
Hemorrhoids; Abnormal Arteriovenous (AV) Communications (Fistulas);
Drugs Treatments Used in Venous Diseases; Other Disease of the
Venous and Lymphatic System; The CEAP Classification; Retinal Venous
Occlusion and Thrombosis; Appendix: Forms Used in Venous Diseases.
Readership: Cardiologists and graduate students

in cardiology.
412pp
981-02-3380-9
Pub. date: Jun 1998

US$84 58
Readership: General practitioners and medical students.
190pp (approx.)
1-86094-051-X

US$16 11
Published by Imperial College Press and distributed by

World Scientific Publishing Co.
Medical Science
11
N euroscience
NONANALYTICAL METHODS FOR
MOTOR CONTROL
Progress in Neural Processing Vol. 6
NEURAL MODELING OF BRAIN AND

COGNITIVE DISORDERS
by R Tomovi (Univ. Belgrade), D B Popovi (Univ. Belgrade &

Univ. Miami Sch. of Medicine) & R B Stein (Univ. Alberta)
edited by James A Reggia (University of Maryland), Eytan Ruppin

(Tel Aviv University) & Rita Sloan Berndt (University of Maryland)
During the last few years there has been a rapidly
increasing interest in neural modeling of brain and
cognitive disorders. This multidisciplinary book
presents a variety of such models in neurology,
neuropsychology and psychiatry. A review of work
in this area is given first. Computational models
are then presented of memory impairment in
Alzheimers disease, functional brain reorganization
following a stroke, patterns of neural activity in
epilepsy, disruption of language processes in
aphasia and acquired dyslexia, altered cognitive
processes in schizophrenia and depression, and related disorders. This is the
first book on this topic, with contributions from many of the leading researchers
in this field.
This book describes non-conventional

methods of control of human extremities,
emphasizing the fact that conventional
approaches used in robotics are limited when
used in humans for restoration of reaching
and grasping (goal-oriented movements), and
standing and locomotion (cyclic movements).
The use of artificial neural networks, inductive
learning, skill-based expert systems and
finite-state representation of movements is the
base of this non-conventional control theory.
A specific number of realized applications are included in the book to
illustrate how these computer techniques can improve the function of
assistive systems in physically challenged humans. The theory presented
is applicable to the control of robots and industrial manipulators.
Readership: Medical professionals, neuroscientists, cognitive scientists and

neural modellers.
Readership: Graduate students and scientists in motor control, rehabilitation engineering, neuroscience and robotic research.
496pp
981-02-2879-1
284pp
981-02-2090-1
Pub. date: Nov 1996

US$86 60
THE SEARCH FOR TERRESTRIAL

INTELLIGENCE
FORTHCOMING
COGNITIVE NEUROLOGY
by M Taube & K Leenders (University of Zurich, Switzerland)
An Introduction
by Stefano F Cappa (University of Brescia Medical School &
Universite Vita Salute S Raffaele, Milan, Italy)
The research on human intelligence is based on

almost all disciplines of modern science. The
following questions must be answered: What is
information? How does information processing
emerge? Can we trace the long and tortuous path
of biotic evolution from reflex, through instinct,
towards intelligence? The brain, as the most complex
system of macro- and micro-structures, unifies
energetic, electrical and chemical phenomena and
carries human intelligence. Brain functions include
memory, emotions, attention, etc. Are there gender
differences? Speech, self-consciousness and the feeling of free will are tools
of intelligence. What about genius, common sense and personality? Lies, myths,
aesthetics and morality are inseparable parts of human intelligence. What about
the chances and threats for human intelligence in the distant future?
The aim of this book is to provide an introduction to this basic science,

from possible applications to the clinical practice of cognitive neurology. It
attempts to integrate cognitive neuroscience and the clinical practice of
behavioural and cognitive neurology. For this reason, the review of the classical
syndrome of neuropsychology, such as aphasia, unilateral neglect and dementia,
is preceded by a summary of current cognitive models. The first section is
thus devoted to selective summaries of current models of cognitive functions
and of their neurological correlates; the second discusses diagnostic issues;
the third provides an overview of clinical presentations, and attempts an
integration with the first section; finally, the fourth section is devoted to
treatment and management issues.
Contents: Introduction to Cognitive Neuroscience: Language; Attention;
Perception and Action; Memory; Executive Functions; Emotions; The Assessment
of Cognitive Dysfunction: The Mental Status Examination; Neuropsychological
Testing; Clinical Presentations of Cognitive Disorders: Selective Cognitive
Impairment Aphasia; Apraxia; Spatial Disorders; Agnosia; Amnesia; Frontal
Lobe Syndrome; Brain Failure Delirium and Dementia; Alzheimers Disease;
Vascular Dementia; Picks Disease and Frontotemporal Dementia; Other Causes
of Dementia; Cognitive Aspects of Other Neurological Disorders Traumatic
Brain Damage; Movement Disorders and MS; HIV Infection; Epilepsy; Psychiatric
Disorders; Treatment in Cognitive Neurology: Mechanisms of Recovery; Cognitive
Rehabilitation; Pharmacological Treatment; Psychological and Social Issues.
M Taube, a nuclear chemist specializing in the cosmic evolution of matter

and energy, and K Leenders, an academic neurologist and head of the positron
emission tomography (PET) program at the Paul Scherrer Institute, address those
questions in this fascinating book on human intelligence.
Contents: Intelligence and Information; Universe Creates Life; Life Breeds
Intelligence; Brain Carries Intelligence; Brain Processes Intelligence; Tools of
Intelligence; Everyday Intelligence; Intelligence Inside; Artificial Intelligence;
Extraterrestrial Intelligence; Future Intelligence.
Readership: General.
Readership: Neuroscientists and psychologists.
250pp (approx.)
1-86094-128-1
Pub. date: Nov 1995

US$63 43
448pp
981-02-3269-1

US$38 26
Pub. date: May 1998

US$48
33

Publishing Co.
Medical Science
12
G eriatric Medicine
N eurology
NEUROPATHOLOGY OF EPILEPSY
FORTHCOMING
edited by F Scaravilli (Institute of Neurology, Queen Square, London)
DRUGS AND THE OLDER POPULATION
The multi-authored book intends to describe the

neuropathological appearances associated with
epilepsy in childhood and in adults and is based
on personal experience of authors working at
institutions in the UK and USA who have a strong
commitment with epilepsy. The literature on the
subject is reviewed. Special emphasis is given to
correlations between physical signs and symptoms,
radiological presentation, suitability to various
operative procedures and pathological findings.
The book will include chapters by physicians,
physiologists, radiologists, neurosurgeons, all with special interest in the field
of epilepsy. The description of the pathological features will include
immunohistochemical data as well as results of morphometric analysis.
edited by Peter Crome (University of Keele) & Gary Ford

(University of Newcastle-upon-Tyne)
This book is designed for all those with a scientific interest in drug treatment
and the older population. The authors have all been chosen for their
expertise in the field and have been drawn from both sides of the Atlantic
and South Africa. The contents fall into two parts general principles
of drug use as they apply to the elderly, and specific chapters dealing
with common clinical areas. The editors aim to provide a concise up to
date, evidence-based, resource book.
Readership: Physicians, geriatricians, old age psychiatrists, general
practitioners, clinical pharmacologists, pharmacists, drug regulators and
other health professionals.
300pp (approx.)
1-86094-099-4
US$58 40
Contents: Epilepsy: Epidemiology, Presentation and Classification (D R Fish);

Pathophysiology of Experimental Epilepsies (J G R Jefferys & R B Traub);
Neuroradiology in Epilepsy (J M Stevens); The Surgical Treatment of Epilepsy
(W Harkness & K Veerasarn); Pathology of Epilepsy in Childhood (D D Armstrong
& E M Mizrahi); The Neuropathology of Epilepsy in Adults (M Thom & F
Scaravilli); Rasmussens Syndrome (M Honavar); Hippocampal Sclerosis (W
van Paesschen & T Rvsz).
Published by
Imperial College Press
and distributed by
Readership: Neuropathologists, physicians, physiologists, neurosurgeons and

radiologists.
616pp
981-02-3170-9
Pub. date: Jul 1998

US$86 60
HANDBOOK OF NEUROLOGY
by Minoru Oishi (Nihon Univ.)
NON-NEURONAL CELLS IN ALZHEIMERS

DISEASE
This volume deals with the principles of neurological

diagnosis and treatment. The management of
common and treatable neurological diseases is
presented in a concise format, making the book
a handy, practical manual. Each page of the book
consists of a table or figure designed to be easily
memorized; these tables should be useful especially
to those preparing for examinations. This book will
be a valuable reference to both students and
residents.
edited by P Zatta & M Nicolini (Univ. Padova, Italy)

Contents: Foreword (P Zatta & M Nicolini); The Blood-Brain Barrier in Aluminium
Toxicity and Alzheimers Disease (W A Banks et al.); Cerebrospinal Fluid
Biochemical Markers in Alzheimers Disease (K Blennow); Platelet and Erythrocyte
Membrane Microviscosity in Alzheimers Disease: The Effect of Metals (S J
van Rensburg et al.); Erythrocyte Aging, Anion Exchange Proteins, and Alzheimers
Disease (G J C G M Bosman & W J de Grip); Structural and Functional Changes
in Erythrocytes and Platelets in Alzheimers Disease (I Hajimohammadreza &
M J Brammer); The Amyloid Protein Precursor of Alzheimers Disease in Human
Platelets and Kidney (Q X Li et al.); Proliferative Properties of Skin Cultured
Fibroblasts in Alzheimers Disease (S Sorbi & G Tesco); Membrane Cytoskeletal
Protein Alterations in Alzheimers Disease (D A Butterfield); Mitochondria,
Aging, and Neurological Diseases (J P Blass et al.); The Role of Microglia and
Astrocytes in Amyloid Deposition in Alzheimers Disease (D W Dickson et
al.); Relationships of Glia to Inflammatory Mechanisms of Alzheimers Disease
Pathogenesis (L Brachova et al.); The Role of Microglial Cells in Alzheimers
Disease (D M A Mann); Glial Cell Extracellular Matrix in Alzheimers Disease
(D A Dewitt et al.); Role of Inflammation and Complement Activation in
Alzheimers Disease (R Veerhuis et al.); Non-Neuronal Cells Involved in bAmyloid Deposition in Alzheimers Disease (H M Wisniewski & J Wegiel);
Trace Elements in Non-Neuronal Tissues in Alzheimers Disease (W D Ehmann
et al.).
Contents: Neurological Approach; Mental Status;

Cranial Nerves; Motor System; Reflexes; Sensory System; Autonomic Nervous
System; Neurological Investigations; Headache; Epilepsy; Infections; Vascular
Diseases; Tumor; Trauma; Toxic and Metabolic Diseases; Degenerative Diseases;
Neuromuscular Diseases; Pediatric Neurology; Psychiatry.
Readership: Medical students and doctors.
408pp
981-02-3037-0
981-02-3063-X(pbk)
Pub. date: Feb 1997

US$68 47
US$46 32
Readership: Neurologists, neuroscientists, geriatricians, psychiatrists,

epidemiologists, biomedical research scientists, pathologists and graduate
students.
252pp
981-02-2092-8
Medical Science
13
Pub. date: Dec 1995

US$65 45
N ephrology
P aediatrics
CLINICAL NEPHROLOGY
FORTHCOMING
by Woo Keng Thye (Singapore General Hospital & National

University of Singapore)
IMPROVING NEWBORN INFANT HEALTH

IN DEVELOPING COUNTRIES
The book provides a broad review of kidney

diseases with regard to symptoms, investigation
and treatment. It deals with a variety of clinical
entities such as glomerulonephritis, renal
stones, hypertension, urinary infection and
renal failure. Chapters on dialysis and transplantation high-lighting local incidence and
statistics have been included. The current
concepts and therapies of kidney diseases as
well as latest statistics on kidney diseases are
also covered.
edited by Anthony Costello (University College, London) &

Dharma Manandhar (Tribhuvan University, Nepal)
Until recently policy makers and health professionals in developing countries
have neglected newborn care, even though 70% of infant deaths occur during
the first month of life. The principles of essential newborn care are simple:
resuscitation, warmth to avoid hypothermia, early breast-feeding, hygiene,
support for the motherinfant relationship, and early treatment for low birth
weight or sick infants. Putting these principles into practice does not require
expensive high technology equipment.
This important book has been written by experts in newborn care, mostly
from developing countries in south Asia. It contains a review of the current
health status of mothers and newborn infants in the developing world, the
evidence base for cost-effective essential and preventive neonatal interventions
in poor communities, ideas for improving service delivery, and the priorities
for future action and research.
Presently, there are several books in the market written by authors in the
West, but these do not adequately cover the knowledge and experience
of the patterns of renal diseases in the Asia-Pacific region.
Written in a clear and concise style, this textbook will serve a useful and
practical guide for medical students and doctors preparing for their higher
examinations.
Readership: Paediatricians, obstetricians, development workers, and tropical

medicine and public health specialists.
Contents: Structure and Function; Symptoms and Signs in Renal Medicine;

Renal Investigations; Glomerulonephritis; Nephrotic Syndrome; Pathogenesis and Treatment of IgA Nephritis; Lupus Nephritis; Urinary Tract
Infection; Sex and the Kidney; Hypertension and the Kidney; Diuretics;
Kidney Stones; Diabetes Mellitus and the Kidney; Fluid and Electrolytes;
Acid-Base Balance; Clinical Problems in Fluids, Electrolytes and AcidBase Balance; Renal Tubular Acidosis; Renal Tubular Disorders; Systemic
Disease and the Kidney; Pregnancy and the Kidney; Cancer and the
Kidney; Inherited Kidney Diseases; Drugs and the Kidney; Acute Renal
Failure; Chronic Renal Failure; Dialysis; Renal Transplantation.
350pp (approx.)
1-86094-097-8

Publishing Co.
FORTHCOMING
Readership: Medical students and General Practioners.
352pp
981-02-3484-8(pbk)
HAEMATOLOGY IN THE NEWBORN
Pub. date: Jun 1998

US$15 10
by I A G Roberts & N A Murray (Royal Postgrad. Med. Sch., London)
Co-Published with Singapore University Press
Virtually all newborn babies admitted to Neonatal Units for intensive care
develop haematological problems which contribute to their mortality and
morbidity. Until recently, the mechanism of these disorders has been poorly
understood. This book provides a problem-oriented approach to fetal and
neonatal haematology of interest to haematologists, neonatal paediatricians and
fetal medicine specialists. Using the clinical and laboratory features (eg.
thrombocytopenia) and the age of the fetus or neonate as a guide to the nature
of the haematological problems likely to be encountered, this book will be
of unique practical value to these specialists. It also reviews current scientific
knowledge about the biology of fetal and neonatal haemopoiesis and Novel
therapeutic and investigative advances for their management.
A PRACTICAL APPROACH TO CLINICAL

PAEDIATRICS
by J M Gupta & D W OGorman-Hughes (Univ. New South Wales)
Contents: Acute Abdominal Pain; Child Physical Abuse (Non-Accidental Injury
in Infants and Young Children); Separation Anxiety; Does the Child Have
Cancer?; Congestive Cardiac Failure; Recurrent or Persistent Cough; Depression
in Childhood; Acute Diarrhoea with Vomiting; The Dysmorphic Child; Middle
Ear Infection; Enuresis; Acute Fever in Infants and Children; The Floppy Infant;
Goitre; Heart Murmurs; Immunisation Schedule; Inguino-Scrotal Swellings in
Childhood; Joint Pain; The Limping Child; The Pale Child; Rash; Seizures in
Childhood; Tall Stature; Strabismus; Undescended Testes; Sore Throat; Vaginal
Discharge and Vulval Irritation; Wheezing; and other papers.
Contents: Haemopoiesis in the Embryo and Fetus; Haemopoiesis in the Normal

Term Baby; Methods of Assessing Haemopoiesis in the Fetus and Neonate;
Haematological Disorders Presenting in the Fetus; Haematological Disorders
Presenting in the First Few Days of Life; Haematological Disorders Presenting
Later in the Neonatal Period; Haematological Problems Presenting with Neonatal
Jaundice; Haematological Aspects of Neonatal Infection; Haematological Aspects
of System Disease; Future Prospects for Management of Haematological Problems
in the Fetus and Neonate.
Readership: Medical students, residents (interns) and medical practitioners in

general practice.
232pp
981-02-1849-4
981-02-2136-3(pbk)
Readership: Paediatricians.
250pp (approx.)
1-86094-049-8
Pub. date: Apr 1996

US$53 39
US$30 22
Medical Science

US$48 33

US$48 33

Publishing Co.
14
P aediatrics
Psychiatry
ALUMINIUM TOXICITY IN INFANTS

HEALTH AND DISEASE
FORTHCOMING
MUNCHAUSENS SYNDROME BY PROXY
edited by P F Zatta (Univ. Padova, Italy) & A C Alfrey (Medical

Ctr., Denver, USA)
Current Issues in Assessment, Treatment and Research

edited by Gwen Adshead & Deborah Brooke (Broadmoor Hospital, UK)
Aluminium is the most abundant metal ion

in the biosphere and we are continuously
exposed to it in our everyday life through
food, beverages, pharmaceutical products,
etc. This book is a current and comprehensive review of the biochemistry,
metabolism and toxicity of aluminium
undertaken by an international group of
authors, many of whom are outstanding
authorities in their respective fields. In
contrast with previous books on this topic,
much of the subject matter is unique, in that it is primarily directed
at aluminium nutrition and toxicity in infants and children. This book
covers many aspects of aluminium toxicity in infants including for
instance the embryo-fetal as well as the neurodevelopmental effects of
this element, contamination of pharmaceutical products, and individual
sensitivity through vaccines using aluminium as an adjuvant.
This important book reviews the current state of knowledge of Munchausens syndrome
by proxy, a type of child abuse which causes wide concern. Two main areas are
covered, which will be of particular interest: new directions in research, and treatment
of the perpetrator in and outside the family. The book also considers the ethical
and legal issues raised by this problematic behaviour, which involves many different
types of professionals and has a heavy cost not only for services but also for victims
and perpetrators.
Unlike other books, this volume provides a multidisciplinary perspective, with input
from social workers, paediatricians, child-psychiatrists and lawyers, among others.
It also offers an international perspective, with contributors from the USA, Canada
and Australia.
Readership: Psychiatrists, paediatricians, nurses and social workers.
200pp (approx.)
1-86094-134-6
Published by Imperial College Press and distributed by World Scientific Publishing Co.
Contents: Chemistry, Biochemistry and Physiology: The Importance of

Aluminium Chemistry in Biological Systems (R B Martin); Aluminium26 as a Biological Tracer Using Accelerator Mass Spectrometry (R Flack
& D Elmore); Aluminium Toxicity Depends on the Metal Speciation
(P F Zatta & P Zambenedetti); Aluminium Metabolism (A C Alfrey);
Aluminium and Iron Relationship: Pathophysiological and Clinical
Overview (J B Cannata Andia); Paediatrics: Aluminium in Infancy
(K Simmer); Aluminium Toxicity in Infants (M E McGraw); Aluminiumrelated Bone Disease in Children with Renal Failure (B D Kuizon &
I B Salusky); Aluminium and Antacids in Infants (J W L Puntis); Development and Aluminium Experimental Toxicity (R L Domingo); Paediatric
Pharmacology: Aluminium Content of Parenteral Nutrition Products
(G L Klein); Aluminium-26 as a Biological Tracer Using Accelerator Mass
Spectrometry (A Moreno et al.); Aluminium in Human Albumin Solutions
(B Gammelgaard & O Jns); Reduction of Aluminium Levels in Albumin
Products (Y Uemura et al.); Toxicity of Aluminium Compounds as an
Adjuvant for Vaccines (N Goto); A Public Health Analysis of Dietary
Aluminium (S Humphreys & P M Bolger).
FORTHCOMING
ANXIETY: A MULTIDISCIPLINARY REVIEW

by Peter Tyrer (St. Marys Hospital, Imperial College, London)
Anxiety is everywhere and almost everyone knows what it is and has suffered from
it. For the specialist it is nonetheless a confusing and complex subject in which
psychological and pharmacological theories and treatments clash repeatedly, and there
is great uncertainty over its classification and causes. This book by a clinician and
research worker who has been involved in the treatment of anxiety for over 30 years
aims to combine the important factors of anxiety into an integrated framework which
allows the biological, psychological and social aspects of anxiety to be incorporated.
Contents: General Section: What Is Anxiety?; Measurement of Anxiety; Psychoanalytical
Concept of Anxiety; Physiology of Anxiety; Clinical Section: Classification of Anxiety;
Drug Treatment of Anxiety; Psychological Treatment of Anxiety; Outcome of Anxiety
Disorders; Relationship Between Anxiety and Other Psychiatric Disorders; The Central
Core of Pathological Anxiety.
Readership: Psychiatrists, research workers and medicalstudents.
130pp (approx.)
1-86094-073-0
Readership: Paediatricians, paediatric nephrologists & neurologists,

nutritionists, toxicologists, biochemical toxicologists and postgraduate
students.
260pp
981-02-2914-3

US$34 23

US$24 16
Pub. date: Jan 1998

US$78 54
PAST, PRESENT AND FUTURE OF PSYCHIATRY

IX World Congress of Psychiatry
(In 2 Volumes)
Rio De Janiero, Brazil
6 12 June 1993
edited by A Beigel (Tucson, Arizona, USA), JJ Lopez Ibor, Jr. (Madrid,
Spain) & J A Costa e Silva (Rio de Janeiro, Brazil)
This volume presents the highlights of the IX World Congress of Psychiatry. The
congress was a major event with the participation of over 6000 scientists from all
over the world with the scientific program covering all aspects of contemporary
psychiatry. The 200 papers selected for this volume provide an insight into recent
advances in psychiatry. They discuss a wide spectrum of subjects ranging from the
diagnosis and treatment of mental illnesses to critical issues affecting the future of
mental health care throughout the world. Authors include leading psychiatric clinicians
and researchers throughout the world as well as international mental health policy
makers.
Readership: Psychiatrists and other mental health professionals.
1548pp
981-02-1500-2(set)
Medical Science
15

US$202 147
Public Health / Occupational Medicine

FORTHCOMING
FORTHCOMING
TUBERCULOSIS
UNDERPRIVILEGED AREAS AND

HEALTH CARE
An International Perspective
edited by John D H Porter (London School of Hygiene & Tropical Medicine) &
John M Grange (Imperial College)
by Brian Jarman & Madhavi Bajekal (Saint Marys

Hospital Medical School)
The fact that the World Health Organization has declared tuberculosis a global emergency
indicates the serious inadequacy of the ways in which the control methods at our disposal are
used. Several books on tuberculosis have been published in recent years, but none have taken
a deep and detailed look at the holistic aspects of global tuberculosis control, even though
international agencies are increasingly aware of the importance of the numerous factors other
than the design and efficacy of therapeutic drug regimens. This unique book fills that gap. Although
it deals specifically with tuberculosis, the principles outlined and discussed are relevant to many
other areas of global medicine, including the ever-growing problem of HIV/AIDS.
The book is aimed principally at those involved in the design, establishment and management
of disease control programmes at international, national and local levels, and also at a more
general readership of epidemiologists, public health officers, community psychologists, and others
interested in understanding the human dimension of disease control.
Contents: Introduction to Tuberculosis and Its Control; The Current International Structure; TB
Treatment from the Patients Perspective: Social and Economic Dimensions of Treatment-Seeking
for TB; Alternative Approaches and Future Directions.
Readership: Epidemiologists, public health officers and community psychologists.
200pp (approx.)
Pub date: Spring 1999
1-86094-143-5
US$42
28
TEXTBOOK OF OCCUPATIONAL MEDICINE PRACTICE

edited by J Jeyaratnam & D Koh (NUS)
This book provides a link between occupational health and clinical
practice. As such, the book is suitable for medical students, general
practitioners and postgraduate students in occupational medicine.
Other occupational health practitioners and occupational health
nurses will also find this book useful.
The main approach of most chapters is to examine occupational
health issues and concerns from the standpoint of clinical presentations
of the different organ systems, e.g. respiratory disorders, musculoskeletal
disorders, dermatological disorders. The book also contains chapters
on screening and routine medical examinations, health promotion
at the workplace, assessment of disability for compensation, medical
planning and management of industrial disasters and the prevention
of occupational diseases. Further, case studies have been incorporated in the chapters to make
clear the relevant issues.
The contributors to the book are a mix of international and regional occupational health specialists
and clinicians. This book will be a valuable starting point for the health professionals with an
interest in occupational medicine as well as to those intending to specialize in occupational
medicine.
Since the industrial revolution and the work of Rowntree,

Booth and other social investigators, attention has been
drawn to poor social conditions and their significant impact
on ill health, disability and early mortality for disadvantaged
groups. In the late 1970s, there was a groundswell of public
opinion regarding difficulties being experienced with general
practitioners services in deprived areas and this has continued.
The major focus of this book is to demonstrate that scientific
methods can be used: first, to analyse the nature of the
problems of social deprivation in health care; second, to
present the problem in a way that allows policy conclusion
to be drawn; and third, to provide a basis for action to
formulate a system of allocating resources in relation to the
need for health care provision. This is of particular importance
at a time when the role and funding of GP services are being
reassessed to reflect the increasing demands made on primary
care.
Contents: Background: The Reasons for the Development
of the UPA Score; Development of the Score: The Analytical
and Political Process; Values of the UPA Score: Wards,
Districts, Countries; Changes between Censuses: Variation
Between Small Area and Larger Area Deprivation Scores;
Validation of the UPA Score: General Practitioners Opinions,
Patients Opinions (the Nottingham Health Profile); The
Association with Morbidity and Mortality: Standardised
Mortality Ratios, Infant and Perinatal Mortality Rates and
Morbidity (Limiting Long-Standing Illness); Implementation
of Deprivation Payments Using the UPA Score: Practical
Details; Other Area Composite Deprivation Indices and
Individual Deprivation Variables: Possible Alternatives to the
UPA Score; Future Developments.
Readership: Medical students, doctors, nurses, health service
managers, health economists, family practitioners and general.
200pp (approx.)
1-86094-014-5

US$26 18

Contents: Work and Health (J Jeyaratnam & D Koh); Renal Disorders (K S Chia & E Lee);
Cardiovascular Disorders (W O Phoon); Respiratory Disorders (H S Lee & Y T Wang); Skin Disorders
(D Koh & C L Goh); Haematological Disorders (K S Chia & R Suri); Neurological Disorders
(S E Chia & P N Chong); Mental Health (J L Kearns); Reproductive Disorders (D Headapohl
& J LaDou); Musculoskeletal Disorders (E H Lee & H K Wong); Gastrointestinal and Hepatobiliary
Disorders (T C Aw & M Harrington); Auditory Disorders (K G Rampal & I Noorhassim); Eye
Disorders (M A Cooke); Occupational Cancers (K S Chia & H P Lee); Industrial Disasters
Medical Planning and Management (M K Lim et al.); Health Screening and Periodic Medical
Examinations (C S Lai & S M Lee); Health Promotion at the Workplace (I R Gardner); Assessment
of Disability for Compensation (W H Phoon et al.); Prevention of Occupational Diseases
(J Jeyaratnam & D Koh); Index.
Readership: Medical students, general practitioners and postgraduates in occupational health.
448pp
Pub. date: Jul 1996
981-02-2322-6
981-02-2415-X(pbk)
US$84
US$42
Medical Science
61
31
16
Public Health / Occupational Medicine

OCCUPATIONAL HEALTH IN NATIONAL DEVELOPMENT
by J Jeyaratnam & K S Chia (NUS)
... The old method of learning things by
reading textbooks is still one of the best, in
spite of the great advances made in information technology. This is the reason why
it was considered worthwhile to summarize
the first ICOH Seminar Course into a book.
The present book is intended both for selfstudies and as a textbook to be used at
national postgraduate training courses.
Without pretending to cover all fields of
occupational health, the book focuses on
prevention of some of the most obvious
risks, such as pesticide poisoning and work-related cancer. It also
describes the function of different types of occupational health care
systems, and it discusses how to identify needs and to evaluate the
quality of the health care activities. The interconnection between
occupational health care and primary health care systems is described,
and the problems of small-scale industries are highlighted. Also, office

work is discussed because of the new types of problems introduced
by information technology and computers.
This book should be regarded as a complement to, not a substitute
for, more conventional textbooks on occupational health. Being an
organization whose aim is to foster occupational health in the whole
world, ICOH hopes that this book will become well distributed and
well read by occupational health professionals in all industrialising
countries.
from the foreword
by Sven Hernberg (ICOH)
Readership: Occupational health physicians, health care administrators, health
policy makers and postgraduate students.
492pp
Pub. date: Aug 1994
981-02-1464-2
981-02-1465-0(pbk)
US$116 80
US$63 43
S urgery
INTRODUCTION TO ORGAN
TRANSPLANTATION
FORTHCOMING
SURGICAL TALK
edited by Nadey S Hakim (St Marys Hospital, London)

With a foreword by Felix T Rapaport (State Univ. New York, Stony
Brook)
Surgery for Finals

by Andrew Goldberg & Gerard Stansby (Saint Marys Hospital,
London)
As finals approach, medical students often become overwhelmed by
the sheer volume of knowledge required to pass all subjects in one go,
including surgery, medicine, obstetrics and gynaecology, pharmacology
and psychiatry. Clearly the students cannot know each of these subjects in
as much detail as they did during their individual attachments and they need
to concentrate on important topics rather than minutiae.
This volume will act as a useful introduction

to organ transplantation for medical students,
nursing and ancillary staff and non-transplant
clinicians seeking to update themselves on the
present situation in this ever-changing and
evolving field.
British Journal of Surgery, 1998
Whereas existing textbooks cover many topics very well and in great detail,
they are lengthy and difficult to read in a short space of time; also some
subjects are poorly covered and give no real understanding of practical
management and logical thought processes the exact requirements for
passing finals.
This introduction to the field of organ transplantation

provides an excellent overview of the tremendous
progress made in recent decades, and gives a clear
description of the current status of transplant
surgery for students and trainees with an interest in this field. It opens with
introductory chapters on the history of transplantation and the basic science
of immunobiology, and then examines through an organ-based structure the
practice of transplantation in each major system, from skin to intestine.
Surgical Talk: Surgery for Finals is specifically aimed at helping students

pass the surgical final examination; it concentrates on subjects and
concepts that tend to confuse students. Each chapter is like a tutorial,
providing tips on what to say and when to say it and more importantly a
logical approach to answering questions. The book deals with topics
poorly covered elsewhere, such as fluid balance, total parenteral
nutrition, central lines, drains and surgical antibiotics. It also has comprehensive chapters on orthopaedics and urology. The reader will feel as
though they are being taught one to one.
Contents: History of Transplantation (N S Hakim); HLA, The Human Major

Histocompatibility Complex (J Dausset & J Colombani); Transplantation
Immunobiology (M J Dalman); Ethical Issues in Transplantation (C J Rudge);
Living Donor Transplantation (A J Matas); Skin Transplantation (J R C Telfer
& D M Davis); Adult Renal Transplantation (L Goldberg & D Taube); Paediatric
Renal Transplantation (O N Fernando); Liver Transplantation (M West &
R W G Gruessner); Heart Transplantation (T J Kroshus & V R Kshettry);
Lung Transplantation (S C Clark & J H Dark); Bone Marrow Transplantation
(S R McCann); Corneal Transplantation (C K Rostron); Pancreas Transplantation
(V E Papalois & N S Hakim); Small Bowel Transplantation (V E Papalois
& N S Hakim); Maintenance of Physiological Homeostasis in Organ Donors
in the ICU (J Jones); Prescribing for Transplant Patients (M Kamps); New
Immunosuppressive Drugs in Organ Transplantation (V E Papalois & N S Hakim);
Infection in Transplantation (B P Madden).
Contents: The Exam; Surgical Talk (how to speak the right language for the
exams); Fluid Balance and Parenteral Feeding; Pre- and Post-operative
Management; Trauma, Shock, Head Injury and Burns; Liver, Biliary Tree and
Pancreas; Oesophagus; Stomach and Duodenum; Small Intestine and Colon;
Rectum and Anus; The Acute Abdomen; Breast Surgery; Lumps in Head and
Neck and Skin; Hernias; Vascular Disease; Urology; Orthopaedics.
Readership: Transplant surgeons and trainees.
Readership: Medical students.
250pp (approx.)
1-86094-077-3
272pp
1-86094-025-0

US$28 19

Publishing Co.

Publishing Co.
Medical Science
Pub. date: May 1997

US$48 33
17
S urgery
M edical Imaging
ADVANCED TECHNIQUES IN GASLESS

LAPAROSCOPIC SURGERY
A PRIMER OF MAGNETIC RESONANCE

IMAGING
Abdominal Wall Lifting with Subcutaneous Wiring

by Daijo Hashimoto (Tokyo Metropolitan Police Hospital)
by J W Hennel (The Niewodniczanski

Inst. of Nucl. Phys., Poland), T KrystWidz gowska (Inst. of Psychiatry &
Neurology, Poland) & J Klinowski (Univ.
Cambridge)
Contents: Part 1: Laparoscopic Cholecystectomy and Advantages of the

Abdominal Wall Lifting Method; Part 2: Preparation for Laparoscopic
Cholecystectomy with Abdominal Wall Lifting; Part 3: A Method of Abdominal
Wall Lifting and Operative Procedure in Laparoscopic Cholecystectomy; Part
4: Difficult Cases, Intraoperative Accidents, and Their Management; Part 5:
Computer Aided Surgery of the Gallbladder and Liver; Part 6: Recent Technical
Advances in Laparoscopic Surgery; Part 7: Various GI Operations with Abdominal
Wall Lifting Method; Part 8: Endoscopy-Assisted Surgeries with Lifting Technique
in Other Fields.
This book is concerned with imaging of the interior

of the human body using signals originating from
magnetic moments of hydrogen nuclei and detected
using a technique known as magnetic resonance.
It explains the method and gives examples of
applications.
The book is addressed to those who would like to understand the principle
of the method exactly, but do not have university training in physics and
mathematics. It will therefore be very useful to medical practitioners and
researchers, radiologists, and auxiliary workers in the health service.
Readership: Surgeons.
268pp
981-02-2208-4
981-02-2247-5(pbk)
Pub. date: Nov 1995

US$83
57
** (Please refer to order form)
Contents: The Fundamentals: Periodic Motion; A Few Words About Vectors;

The Fourier Transformation; Magnetic Moments and Magnetic Fields;
Electromagnetic Induction; Sampling the Potential; Atomic Nuclei; Magnetic
Behaviour of the Nucleus: Nuclear Magnetization; Longitudinal Relaxation;
Larmor Precession; Nuclear Magnetic Resonance; Free Induction Decay; Spin
Echo; Imaging: Experimental Procedure; Transformation of the Results; Contrast
Adjustment; Contrast Agents; MRI Angiography; Localized Spectroscopy; Practical
Aspects: Specimen Images; Indications and Contraindications.
P lastic Surgery
Readership: Physicians, physiologists, cardiologists and nurses.
96pp
1-86094-060-9
NEONATAL SURGERY OF THE CLEFT LIP

AND PALATE

Publishing Co.
by S N Desai (Stoke Mandeville Hospital, UK)

Traditionally, cleft lip repair has been carried out
around 10 to 12 weeks of age. There have been
surgeons who have done surgery in newborn but
there has been no series where cleft lip repair has
been carried out in the first 48 hours as a routine
procedure over a long period with long term results.
The authors unit has performed this operation
routinely for the past 25 years and collected data
on the speech, hearing, growth and appearance
of the children, who are now in their 20s. The
main argument against this procedure was the
anaesthetic risk in performing surgery so early in life. Having analysed all the
arguments for and against, the author provides a detailed analysis of the work
in this book. As far as is known, this is the only book to analyse the longterm results of surgery in newborn. A number of centres around the world
are contemplating or performing sugery in newborn and this would be a very
good background for emphasising and promoting the operation.
PRACTICAL CLINICAL ULTRASONIC

DIAGNOSIS
edited by Lin Liwu (Medical Univ. of Fujian, China)
This book is written by several authors based on
their wide experience and on materials painstakingly
accumulated through many years of practice. The
result is a comprehensive volume which deals with
detailed aspects of clinical ultrasonic diagnosis.
The scope of this book covers the clinical ultrasonic
diagnosis of diseases of the liver, biliary system,
pancreas, spleen, gastrointestinal tract, kidney,
urethra, bladder, adrenal gland, prostate gland,
scrotum, heart, chest and even the use of clinical
ultrasonic diagnosis in the department of obstetrics
and gynecology. This book has three special features. Firstly, the anatomic
and pathological changes caused by common diseases of these organs and
their corresponding ultrasonograms are described in detail. Secondly, the
diseases of organs such as the heart, abdomen, chest as well as in the department
of obstetrics and gynecology, are described in a concise and systematic manner
for easy reading. Finally, this book includes over 400 illustrations of the typical
images of different kinds of diseases, accompanied by their corresponding line
drawings.
Contents: Foreword (S T Lee); Introduction (S N Desai); Cleft Lip Repair

(S N Desai); Anaesthesia for Newborns (N D Chaubal); Orthodontic Management
(F B Christie); Alveolar Bone Grafting and Orthognathic Surgery (M M Mace);
Hearing in Cleft Children (M A Too-Chung); Speech in Cleft Children
(M Copeland); Nursing in Cleft Children (C Duffin); Cleft Palate Repair at Four
Months (S N Desai); Conclusion (S N Desai).
Readership: Plastic surgeons, orthodontists, oral surgeons, otolaryngologists,
speech therapists, speech pathologists, anaesthetists, paediatricians and child
psychologists.
256pp
981-02-3116-4
This book is therefore invaluable to specialists, clinical doctors and to trainees

using ultrasonic diagnosis.
Pub. date: Nov 1997

US$38 26
Readership: Medical students, postgraduates and doctors.
480pp
981-02-2922-4
Medical Science
Pub. date: Jan 1998

US$18 12
18
Pub. date: Aug 1997

US$78 54
M edical Imaging
The book will be a valuable text and reference for students pursuing an
undergraduate course in medical imaging. It will also be a useful reference
for all readers interested in the subject of medical imaging.
FORTHCOMING
AN INTRODUCTION TO THE PRINCIPLES

OF MEDICAL IMAGING
Contents: A Short History of Medical Imaging; The Principles of Tomography;

Atomic and Nuclear Physics; Radiation Protection; Diagnostic X-Rays; Nuclear
Medicine: Gamma Imaging; Magnetic Resonance MRI; Ultrasonic Imaging;
Imaging in Clinical Practice; Fourier Analysis; Mathematics of Tomography.
by C N Guy (Imperial College) & D H Ffytche (Institute of Psychiatry,

London)
This book has been written based on the authors experience with bulk
magnetic properties of the spin glass state and superconducting quantum
interference device (SQUID) and their interest in the various medical
applications of physics, such as MEG, PET and MRI. It focuses on finding
ways to combine the data from the various techniques in order to create a
general method for imaging information processing in the brain.
Readership: Medical physicists, Radiologists, medical students
300pp (approx.)
1-86094-138-9
US$38 26

Publishing Co.
C linical Methods
A PRIMER OF CHEMICAL PATHOLOGY
CHEMICAL PATHOLOGY: INTERPRETATIVE

POCKET BOOK
by Evelyn S C Koay (NUS) & Noel Walmsley (ClinPath Labs.

Adelaide, Australia)
by R N Walmsley & H J Cain (Clipath Lab. Adelaide)
... the strength of this book is its overall

clarity and comprehensiveness. It fills a gap
between the basic undergraduate text and
a reference book. It will be valuable to the
undergraduate student with an interest in the
subject and will provide a thorough grounding in chemical pathology for the postgraduate students...
G Bayly
The Bulletin of the Royal College of
Pathologists, 1996
This is a pocket book to assist in the interpretation

of routine biochemical results. It contains comprehensive tests of causes of abnormalities and
associated algorithms, that is, an aide-memoire
plus flow charts to assist in diagnosis. The material
is based on the authors vast experience in
teaching hospitals and in providing services to
general practitioners.
Contents: Introduction; Sodium; Potassium; AcidBase; Renal Disease; Mineralocorticoids; Calcium;
Phosphate; Magnesium; Uric Acid; Glucose;
Jaundice, Liver Disease; Enzymes; Serum Proteins; Lipids; Thyroid; Adrenal
Cortex; Anterior Pituitary; Reproductive System; Iron; Hypertension; Diarrhoea;
Coma, Polyuria; Nephrolithiasis; Steatorrhoea; Acute Abdominal Pain;
Miscellaneous Analytes; Dynamic Function Tests; Abbreviations; Index.
This book has been written primarily for medical students and junior doctors
in clinical practice, but would also be a useful reference for postgraduate
students in chemical pathology (clinical biochemistry), laboratory scientists,
pathologists and medical laboratory technologists. It covers the field of chemical
pathology, the biochemical basis of disease, and provides a basic understanding
of the relationship between abnormal biochemical test results and disease states.
A rational approach to proper selection and interpretation of biochemical
investigations is adopted for each organ system or analyte covered in the 28
chapters. Emphasis is placed on areas and problems most commonly met with
in clinical practice. Meant primarily as an introductory study book to the subject
rather than as a reference text, the materials have been presented in a clear,
condensed format to aid the study process. The written text is amply supplemented
with relevant illustrations.
Readership: Medical students, interns, general practitioners and clinical

biochemists.
224pp
981-02-2802-3
981-02-2849-X(pbk)
Pub. date: Aug 1996

US$54 37
US$28 19
Contents: Sodium and Water Metabolism; Potassium; Acid-Base and Blood

Gases; Mineralocorticoids; The Kidney and Renal Disease; Calcium; Phosphate;
Magnesium; Urate and Gout; Glucose, Lactate and Ketones; The Hepatobiliary
System; Plasma and CSF Proteins; Enzymes in Diagnosis; Plasma Lipids and
Lipoproteins; The Gastrointestinal Tract; The Hypothalamus and Pituitary Gland;
The Thyroid Gland; The Adrenal Cortex; Reproductive Endocrinology; Iron;
Porphyrins; Biochemical Syndromes of Tumours; Biochemical Aspects of
Hypertension; Inherited Metabolic Diseases; Nutrition, Vitamins, Trace Elements;
Pregnancy, Prenatal Diagnosis and Infertility; Paediatric Chemical Pathology;
Therapeutic Drug Monitoring and Toxicology.
Readership: Undergraduate and postgraduate medical students, clinical
biochemists, medical laboratory technologists, pathologists, internists and lecturers
teaching chemical pathology course.
408pp
981-02-2449-4
981-02-2571-7(pbk)
Pub. date: Feb 1996

US$48 32
US$32 22
Medical Science
19
C linical Methods
T ropical Medicine
CASES IN CHEMICAL PATHOLOGY
FORTHCOMING
A Diagnostic Approach
(3rd Edition)
Tropical Medicine: Science and Practice
SCHISTOSOMIASIS
by R N Walmsley (Gribbles Pathology, Australia), L R Watkinson

(Flinders Medical Ctr., Australia) & E S C Koay (NUS)
edited by A Mahmoud (University Hospitals of Cleveland, USA)

This volume brings together updated fundamental knowledge of the schistosomes,
their biology and epidemiology, the mechanism of disease and a full description
of the pathological sequelae in humans. It concludes with chapters on diagnosis
and treatment prospects of vaccine development and the most significant
controversies regarding immunology and epidemiology.
... the authors cover most of the major areas of importance in dayto-day practice, with particular emphasis on renal, acid-base and
electrolyte disturbances. The cases are well presented, and the
discussions concise yet comprehensive. There are helpful tables and
algorithms for investigation. Rather more references are provided than
is usual in books of this sort, which will be valuable to teachers and
those studying for postgraduate examinations. This is a working book
it handles well and it will stay open on the desk or bench ...
It deserves to be widely known, and widely used.
W J Marshall
Bulletin of the Royal College of Pathologists
Contents: The Schistosomes and Their Intermediate Hosts (R Sturrock); Molecular

Organization and Genetics of Schistosomes (A Simpson & G Franco);
Epidemiology and Dynamics of Transmission (R Anderson); Resistance to
Infection in Humans and Experimental Animals (D Dunne & A Butterworth);
Initiation and Regulation of Disease in Schistosomiasis (C King); Disease in
Schistosomiasis Hematobia (C King); Disease in Schistosomiasis Mansoni in
Brazil (A Prata); Disease in Schistosomiasis Mansoni in Africa (J Ouma et al.);
Disease in Schistosomiasis Japonica (R Olveda); Disease Due to Other Schistosome
Species (C King); Principles of Diagnosis and Therapeutic Management (J Cook);
Strategies for Control of Infection and Disease (R Bergquist); Prospects for
Antischistosome Vaccine (S James & D Colley); Controversies in Mechanisms
of Human Immunity and Pathogenesis (A Sher & A Mahmoud).
The book is well made and attractively printed.

Richard T OKell
Clinical Chemistry, 1993
This book deals with the clinical aspects and
interpretation of test results of disorders commonly encountered by clinicians and the
chemical pathology laboratory. It is structured
around actual case material seen in the authors
laboratory and emphasizes the selection of tests
and interpretation of results. Each of the 25
chapters deals with a single analyte or a single
organ system and includes case material, discussion
of evaluation of the particular disorder, and
interpretation of test results. The content is nonspecialised enough to be followed by general practitioners but sufficiently
detailed to appeal to the more specialised practitioner. It will be particularly
useful to medical students who first embark on a study of this subject, the
clinical biochemists at the bench, and students preparing for College
examinations such as those for physicians, pathologists and surgeons.
Readership: Undergraduates and researchers in immunology, clinical methods/

lab medicine, and tropical medicine and hygiene.
550pp (approx.)
1-86094-146-X

Publishing Co.
FORTHCOMING
Tropical Medicine: Science and Practice
AMEBIASIS
Contents: Introduction; Sodium; Potassium; Acid-Base; Renal Disease;

Mineralocorticoids; Calcium; Phosphate; Magnesium; Urate; Glucose; Liver
Disease; Enzymes; Proteins; Lipids; Thyroid Disease; Adrenal Cortex; Pituitary
Disease; Plasma Iron; Hypertension; Diarrhoea; Coma; Polyuria; Nephrolithiasis;
Steatorrhoea; Acute Abdominal Pain.
edited by Jonathan I Ravdin (University of Minnesota)

Amebiasis presents the most up-to-date overview of the field, encompassing
all aspects of epidemiology, clinical management, and research. The most
authoritative physicians and scientists worldwide have contributed to this effort.
Future research directions are well defined by those at the cutting edge of
the field. Students, postgraduate trainees, clinicians and researchers will find
great value in these concise reviews.
Readership: Medical students, clinical biochemists, postgraduate students

preparing for higher degree exams such as for physicians, pathologists and
surgeons, and general practitioners.
464pp
981-02-1067-1
981-02-1068-X(pbk)
Pub date: Spring 1999

US$96 65
Pub. date: Oct 1992

US$78 57
US$28 20
Contents: Entamoeba histolytica: An Overview of the Biology of the Organism

(C G Clark et al.); Epidemiology (T Jackson); Mechanisms of Host Resistance
to Entamoeba histolytica (D Campbell & K Chadee); Pathogenesis and Molecular
Biology (G Ramakrishnan & W A Petri, Jr.); Clinical Manifestations and Diagnosis
(S L Reed); Treatment of Amebiasis (K C Kain et al.); Prevention and Potential
of New Interventions (S L Stanley, Jr.); Unresolved and Open Questions in
Amebiasis Research (D Mirelman); Controversies in Clinical Management (J
I Ravdin).
Readership: Students, postgraduate trainees, clinicians and researchers in tropical
medicine.
300pp (approx.)
1-86094-133-8

US$46 31

Publishing Co.
Medical Science
20
Biochemistry
T ropical Medicine
FORTHCOMING
FORTHCOMING
Tropical Medicine: Science and Practice Vol. 1
MYELOPEPTIDES
LYMPHATIC FILARIASIS
by Rem V Petrov, Augusta A Mikhailova, Larissa A Fonina (Russian Academy

of Sciences) & Rodion N Stepanenko (Russian Ministry of Health)
edited by Thomas B Nutman (Natl Inst. of Health, USA)
Myelopeptides are a new class of endogenous bioregulatory peptides. Each has its own
definite immunoregulatory activity and differs in their final effects and mechanisms of action.
Myelopeptides act as immunocorrectors and thus prevent the development of immunodeficiency
states. They have an antitumor effect which contributes to the retention of active immune
defense in the tumor-bearing body. The ability of myelopeptides to induce terminal cell
differentiation in hemopoietic disorders (in particular, in leukemia) is demonstrated. The
protective effect of a single myelopeptide in bacterial contagion of animals, which is due
to the stimulation of macrophage phagocytosis, is established. In this book, the concept
of the general biological value of cytokines, including peptide endogenous regulators, is
discussed. Myelopeptides are promising in the development of a new generation of medicinal
preparations because of their endogenous origin, low molecular weight, directed action and
absence of side effects.
This is the first in a series dedicated to the understanding of

tropical diseases. This volume examines the basic biology and
clinical expression of lymphatic-dwelling filarial parasites,
parasites affecting over 90 million people in the tropical and
subtropical regions of the world. Although it is responsible for
the disfiguring elephantiasis, infection with this parasite leads
to a spectrum of clinical manifestations. The underlying
pathogenetic mechanisms of infection, its epidemiology, diagnosis,
treatment and prevention of these often devastating vectorborne diseases will be the focus of this book.
Contents: Introductory Overview and History (T B Nutman); The
Biology of the Lymphatic Dwelling Filariae (A L Scott); Epidemiology
(E Michael); Resistance to Infection (J Kazura); Pathogenesis and
Clinical Manifestations (V Kumaraswami); Diagnosis (J McCarthy);
Treatment (D Addis); Prevention and Control (E A Ottesen);
Controversies in Lymphatic Filarial Infection: Immunological
Control of Reactivity to Parasite Antigens/Tolerance (R Maizels);
Bacteria as Cause of Lymphatic Pathology (G Dreyer & W Piessens).
This book is intended for those interested in medical and biological problems: lecturers
and students in medical and biological universities, scientists and researchers from medical
and biological laboratories, and other professionals involved in medical and biological
research.
Contents: New Immunoregulatory Bone Marrow Mediators, Myelopeptides: Discovery of
Bone Marrow Factor(s); Myelopeptides: A Group of Bone Marrow Bioregulatory Mediators;
Myelopeptides Participation in the Human Immune System Functioning; Individual
Myelopeptides: Structure, Function, Mechanism of Action: Isolation, Identification and
Synthesis of Myelopeptides; Myelopeptide 1: An Endogenous Immunoregulator with
Immunocorrective Activity; Myelopeptide 2: Immunoregulatory Peptide with Antitumor Effect;
Myelopeptide 3: Stimulator of Macrophages Phagocytosis; Myelopeptide 4: Cell Differentiation
Factor; Myelopeptides: A New Class of Endogenous Bioregulatory Peptides.
Readership: Medical doctors, students and researchers in cell/

molecular biology, microbiology and immunology.
250pp (approx.)
1-86094-059-5

US$24 16

Readership: Bio-chemists and immunologists.
200pp (approx.)
981-02-3507-0
US$34
25
Gene Therapy
FORTHCOMING
GENE THERAPY FROM LABORATORY TO THE

CLINIC
MOLECULAR APPROACHES TO
TUMOR IMMUNOTHERAPY
edited by Kam M Hui (Inst. of Molecular & Cell Bio., Spore)
edited by Y Liu (New York University)
... the format and length of this text makes it an easy to read introduction to
the area of gene therapy. It would be ideally suited to the reader with a working
knowledge of one particular area of gene therapy who wished to gain a broader
perspective of the field. Medical scientists in particular would find this a useful
adjunct to their current textbooks.
R Ward, Cancer Forum, 1995
The articles in this book are contributed by leading scientists

working in the fields of immunology, tumor immunotherapy, and
gene therapy. The book identifies the opportunities that modern
immunology and molecular biology have provided for tumor
therapy. Moreover, it contains critical essays that analyze the
progress and obstacles of tumor immunotherapy.
Contents: Molecular Basis of Antigen Recognition by T and B
Cells (C A Janeway); Molecular Mechanism of Antigen Processing
and Presentation (A Rudensky); Molecular and Cellular Basis of
T Cell Costimulation (Y Liu et al.); Cytokines as Mediators in
T Cell Activation and Regulation (A OGarra); SelfNonself
Discrimination of Anti-Tumor Immune Responses (S Sarma & Y
Liu); Processing, Presentation and Identification of Tumor Antigen
(P Srivastava); Mutated Oncogenes as Targets for Tumor
Immunotherapy (A Frey); Mechanisms of T Cell Recruitment into
Tumors (M Maric & Y Liu); T Cell Costimulation and Tumor
Immunotherapy (L-P Chen); Cytokine-Based Tumor Immunotherapy
(G Forni); Tumor Vaccines (N Restifo); Herpes Simplex Virus
Amplicon as Vector for Gene Therapy and Vaccine Development
(X-L Zhang).
Contents: Foreword (R A Weiss); An Introduction to Gene Therapy

and Cancer (Y H Tan); Clinical Strategies and Expectations for
the Molecular Biotherapy of Cancer (H K B Silver & R J Klasa);
Tumor-Directed Cytokine Gene Therapy (C S Chiang et al.);
Therapeutic Applications of Antisense Nuclei Acids (T M C Tan
et al.); Molecular Targeting of Cancer: Retroviral Vector-Mediated
Antisense Nuclei Acid Therapy (Y Zhang et al.); DC-Chol Liposomes
as DNA Carriers for Gene Therapy (A Singhal & L Huang); Accell
Particle Bombardment for Gene Transfer as a Useful Gene Therapy
Technique (N-S Yang et al.); DNA-Coated Microprojectiles for
Gene Delivery into Live Animals (D-C Tang & S A Johnston);
Expression of Foreign Class I Major Histocompatibility Complex
(MHC) Molecules on Experimental Tumors and the Induction of Active Specific Cancer
Immunotherapy (K M Hui); Gene Transfer to the Central Nervous System Mediated by Herpes
Simplex Virus Vectors (J C Glorioso et al.); Adeno-Associated Virus-Based Vectors for Human
Gene Therapy (R J Samulski); Index.
Readership: Physicians, researchers and graduate students in

tumor immunology.
Readership: Scientists, clinical investigators, physicians and graduate students in medical/

biological sciences.
300pp (approx.)
981-02-2793-0
288pp
Pub. date: Nov 1994

US$78 54
Medical Science
21
981-02-1654-8
981-02-1655-6(pbk)
US$91
US$46
63
32
P hysiology
PHYSIOLOGY AND PATHOPHYSIOLOGY
OF TEMPERATURE REGULATION
FORTHCOMING
THE HAEMODYNAMIC EFFECTS OF

NITRIC OXIDE
edited by Clark M Blatteis (The University of Tennessee)

This is a user-friendly monograph designed
for medical students as well as graduate
students and postdoctoral trainees in medicine
and other health-related sciences who need a
comprehensive overview of thermoregulation.
It presents the bases of the modern concepts
in thermal physiology and pathophysiology,
bringing together the disciplines encompassed
by this highly integrative field physiology,
anatomy, biophysics, molecular and cellular
biology, pharmacology, neuroscience,
pathology, medicine, and others into a clear
and concise form that can be read comfortably in a relatively short time.
edited by Robert T Mathie (Royal Postgraduate Medical School,

UK) & Tudor M Griffith (University of Wales College of
Medicine, UK)
Since the discovery of nitric oxide as an endothelium-derived relaxing factor
in 1987, investigations on its precise modes of action have been carried
out at an extraordinary rate. Nitric oxide is now implicated in many
physiological and pathological processes not just in the control of vascular
resistance, but in nerve transmission, cell proliferation, inflammatory responses
and so on.
Despite such rapid progress, no attempt has been made to combine the
current knowledge of this subject matter in a single textbook. This volume
has been written with the above in mind and presents a topical, comprehensive
overview of the biochemistry and the physiological and pathophysiological
effects of nitric oxide as they relate to the cardiovascular system. The
therapeutic implications of nitric oxide are also considered. The text comprises
contributions from many of the leading international authorities on the topic.
Contents: Thermal Physiology: Brief History and Perspectives (A S Milton);

Body Temperature (C M Blatteis); Biophysics of Heat Exchange between
Body and Environment (J Werner); Heat Production Mechanisms: Shivering
(L Jansky); Heat Production Mechanisms: Nonshivering Thermogenesis and
Brown Adipose Tissue (B Cannon & J Nedergaard); Heat Loss Mechanisms
(T Morimoto); Neural Thermal Reception and Regulation of Body Temperature
(J A Boulant); Thermiatrics and Behavior (M Cabanac); Temperature Regulation
in Exercise (B N Johannsen & H Kaciuba-Uscilko); Body Temperature and
Age: Thermoregulation in the Neonates (H P Laburn); Body Temperature
and Age: Thermoregulation in the Elderly (K E Cooper); Fever (C M Blatteis);
Thermoregulatory Consequences of Prolonged Exposure to Thermal Extremes:
Prolonged Exposure to Heat (M Horowitz); Thermoregulatory Consequences
of Prolonged Exposure to Thermal Extremes: Cold Adaptation (E Zeisberger);
Pathophysiological Consequences of Exposure to Thermal Extremes:
Pathophysiology of Hyperthermia (M Horowitz & J R S Hales) ;
Pathophysiological Consequences of Exposure to Thermal Extremes:
Hypothermia and Cold Injuries in Man (J B Mercer); Temperature Regulation
in Special Situations (C M Blatteis).
Contents: The Biochemistry of Nitric Oxide (NO); The Haemodynamic

Effects of NO; Patho/Physiological Effects of NO in the Vascular System;
Therapeutic Implications of NO.
Readership: Students and researchers in physiology, biochemistry and clinical
methods/ laboratory medicine.
400pp (approx.)
1-86094-081-1

US$78 54

Publishing Co.
Readership: Researchers and students in physiology, biochemistry,

biomedical engineering, neural networks, paediatrics, pharmacology/
pharmacy, surgery and toxicology.
308pp
981-02-3172-5
Pub. date: Jun 1998

US$32 22
R eproductive Physiology
Ryanodine Receptor Ion Conduction and Selectivity (A J Williams); Ryanodine
Binding Sites on the Sarcoplasmic Reticulum Ca2+ Release Channel (I I Serysheva
& S L Hamilton); The Ryanodine Receptor: A Report from the Ryanoids (W
Welch); Phosphorylation of Ryanodine Receptors (J A Airey & R He); Ca2+
Release Channel/Ryanodine Receptor -L-Type Ca2+ Channel/Dihydropyridine
Receptor Interactions in Skeletal Muscle (G Meissner); Regulation of Ryanodine
Receptor by Peptide Toxins (G B Gurrola & H H Valdivia); Chemical Modification
of Ryanodine Receptor/Ca2+ Release Channel Activity (V Shoshan-Barmatz &
W Feng); The Role of Ryanodine Receptor in Inherited Muscle Diseases (C
F Louis & J R Mickelson); Single RyR Channel Adaptation (P Velez et al.);
Adaptation, Inactivation and Inhibition in Ryanodine Receptors (G D Lamb
& D R Laver); Regulation of SR Calcium Release in Intact Ventricular Myocytes
(D M Bers).
FORTHCOMING
THE STRUCTURE AND FUNCTION OF

RYANODINE RECEPTORS
edited by R Sitsapesan & A J Williams (Imperial College, London)
This book provides up-to-date information on some of the most important
aspects of ryanodine receptor function and has been written by experts in the
field. Included are reviews of the latest experimental data, critical assessments
of the mechanisms of ryanodine receptor activation and regulation, and the
role of the channel in controlling intracellular Ca2+ release.
The approach to this subject is new. The book focuses on the biochemical
and biophysical aspects of ryanodine receptor research, with particular emphasis
on the single channel properties of reconstituted ryanodine receptors.
Readership: Researchers as well as undergraduate and graduate students in

physiology, biochemistry, pharmacology and biophysics; medical students.
Contents: An Overview of Ryanodine Receptor Structure and Function (R

Sitsapesan & A J Williams); Characteristics of Ryanodine Receptor Type 3
Isoform (RyR3) and Its Homologues (Y Ogawa & T Murayama); The Skeletal
Muscle Ca2+ Release Channel Visualised by Electron Cryomicroscopy (E V
Orlova et al.); Regulation of Ryanodine Receptor Channel Gating (R Sitsapesan);
Medical Science
450pp (approx.)
1-86094-145-1

US$78 53

Publishing Co.
22
H istology
A natomy
ORGAN HISTOLOGY
FORTHCOMING
A Students Guide
by C Hinrichsen (Univ. Tasmania, Australia)
A GUIDE TO DISSECTION OF THE HUMAN

BODY
Contents: Integumentary System: Skin; Skin

Appendages; Endocrine System: Hypophysis and
Diffuse Neuroendocrine and Chromaffin Systems;
Thyroid, Parathyroid and Endocrine Pancreas;
Suprarenal Glands; Immune System: Cells of the
Immune Response; Lymph, Lymph Vessels, Lymph
Nodes and Tonsils; Thymus and Spleen;
Cardiovascular System; Respiratory System: The
Upper Airway; The Lungs; Digestive System: Oral
Cavity; Teeth; Esophagus and Stomach; Intestines;
Digestive Glands; Urinary System: Kidney; Renal
Pelvis, Calyces, Ureter, Bladder and Urethra; Male Reproductive System: The
Testis; Genital Duct System, Accessory Glands and External Genitalia; Female
Reproductive System: Ovary; Uterine Tubes, Uterus and Vagina; External
Genitalia and Mammary Glands; Placenta; The Eye; The Ear.
by F P Lisowski (University of Tasmania)

This invaluable manual is intended to guide and facilitate human anatomical
dissections. It is flexible enough for use in long as well as short courses, and
is thus structured in such a way that the dissection of the body can be completed
in 110 to 160 hours. Although some medical schools have reduced the amount
of dissection, the North American schools have lengthened their courses. The
manual can also be used in those courses where only part of the body is
dissected and even in the study of prosected material. It can be particularly
useful as a link with real anatomy when used together with computerisedanatomy programs; many curricula emphasise that the student should go back
and forth between the body and computer programs. The guide is also useful
where students do not dissect but merely look at atlases, prosections and
models, by providing a link to real, living and variable anatomy.
Contents: Upper Limb: Pectoral Region and Axilla; Front of Arm and Cubital
Region; Superficial Dissection of Back of Trunk, Scapular Region and Back
of Arm; Joints of the Shoulder Region; Front of Forearm and Hand; Joints of
Free Upper Limb; Lower Limb: Anterior and Medial Aspects of the Thigh;
Gluteal Region and Posterior Aspect of the Thigh; Hip Joint, Popliteal Fossa
and Back of the Leg; Anterior and Lateral Aspects of the Leg and Dorsum
of the Foot and the Knee Joint; Sole of Foot; Tibiofibular Joints, Ankle Joint
and Joints of the Foot; Thorax: Thoracic Walls and Lungs; Superior and Middle
Mediastinum; Superior and Posterior Mediastinum and Joints of Thorax; Abdomen:
Anterior Abdominal Wall and External Genitalia; Abdominal Cavity, Stomach
and Intestines; Liver, Pancreas, Duodenum and Spleen; Kidney, Suprarenal and
Posterior Abdominal Wall; Pelvic Viscera; Blood Vessels, Nerves and Muscles
of the Pelvis; Perineum; Head and Neck: Posterior Triangle of the Neck; Anterior
Triangle of the Neck; Face and Scalp; Cranial Cavity; Orbit and Lacrimal
Apparatus; The Eyeball; Parotid and Infratemporal Regions and
Temporomandibular Joint; Submandibular Region and Deep Dissection of the
Neck; Deep Structures of the Back of the Neck and the Trunk; Nasal Cavity;
Oral Cavity; Soft Palate and Pharynx; The Larynx; The Ear.
Readership: Medical students, biology students and paramedical personnel.
428pp
981-02-2612-8
981-02-2613-6(pbk)
P harmaceutics
PARTICLEPARTICLE ADHESION IN
PHARMACEUTICAL POWDER HANDLING
by Fridrun Podczeck (University of London)
Readership: Undergraduates in anatomy for medicine, dentistry, human biology,

osteopathy, chiropody, science, and postgraduates in the clinical sciences and
those aiming to teach anatomy.
350pp (approx.)
981-02-3528-3
981-02-3569-0(pbk)
This monograph describes the physical principles

of adhesion between particles and surfaces. These
principles are applied to pharmaceutical processes
involved in the manufacture of solid dosage forms
such as powders, granules, tablets and dry powder
inhalations. To help in the understanding of these
systems, physical properties of solid surfaces, and
an introduction to the theory of friction is given.
Techniques for measuring particle adhesion and
fracture mechanical properties of powders are
introduced, as far as these are relevant to the
processes discussed. The philosophy of the book deviates from that of standard
pharmaceutical textbooks, in that it focuses primarily on physical principles
involved in the manufacture of dosage forms rather than describing these
processes purely by observation.

US$56 38
US$32 22
Co-published with Singapore University Press
BASIC NEUROANATOMY
by D T Yew, W H Kwong (The Chinese Univ. of Hong Kong) &
M C Yu (Univ. Medicine & Dentistry, New Jersey)
Contents: Introduction; Spinal Cord; Brainstem and
Reticular Formation; Diencephalon; Cerebral
Cortex; Cerebellum; Basal Ganglia; Limbic System;
General Sensory System; Specific Sensory Systems;
Motor System; Autonomic Nervous System;
Meninges and Vascular Supply of the Central
Nervous System; Review of Specific Lesions of the
Central Nervous System.
Contents: Fundamentals of Adhesion of Particles to Surfaces; Brief Overview

of the Theory of Friction; Particle Adhesion in Powder Assemblies; Measuring
Methods.
Readership: Researchers in pharmaceutics, applied physics, materials science
and surface & interface science.
256pp
1-86094-112-5
Readership: Undergraduates in the medical sciences

and dentistry, and allied health professionals.
200pp
981-02-2553-9
981-02-2607-1(pbk)
Pub. date: Aug 1998

US$48 35

Publishing Co.
Pub. date: Apr 1997

US$42 29
US$24 17
Medical Science
Pub. date: Mar 1997

US$68 47
US$34 23
23
T raditional Medicine
INTERNATIONAL COLLATION OF
TRADITIONAL AND FOLK MEDICINE
Volume 3
Volume 1
Northeast Asia Part III

edited by C K Sung (Chonnam National University), J-X Guo
(Shanghai Medical University), P P H But (Chinese University of
Hong Kong), T Kimura (Daiichi College of Pharmaceutical
Science) & B H Han (Seoul National University)
Northeast Asia Part 1

edited by Takeatsu Kimura (Daiichi College of Pharmaceutical
Sciences), Paul P H But (The Chinese University of Hong Kong),
Ji-Xian Guo (Shanghai Medical University) & Chung Ki Sung
(Chonnam National University)
Traditional folk medicine practices in China, Hong

Kong, Japan and Korea all located in Northeast
Asia are comparable. Since different usage of
a folk medicine may reflect cultural or regional
differences, a detailed collation of the folk
knowledge of traditional medicine can help
to identify common applications derived from
different empirical knowledge as well as
variations in appreciation of the value of the same
source in different cultural settings.
In this first volume of a series of books that will

compare the differences and similarities of
traditional folk medicine practiced around the
world, 200 of the most frequently used medicinal
plants in Northeast Asia are selected by the
international editorial board to be featured.
Readership: Medical and research scientists
interested in bioactive components of natural
products.
236pp
981-02-2589-X
This third volume of a series of books continues

with the objective of collating relevant information for showing the differences
and similarities of traditional folk medicines practiced around the world. It
features 198 of the most frequently used medicinal plants and 2 animals in
Northeast Asia as selected by the international editorial board.
A BRIEF HISTORY OF CHINESE MEDICINE

2nd Edition
The folk medical knowledge in each entry includes the scientific names of
the source, local names of the drug, special processing methods, administration
methods, and applications in each country. Contraindications and side effects,
if any, are highlighted. Relevant scientific data on their chemistry and
pharmacology, with references, are also included.
by P Y Ho (Needham Res. Inst.) & F P Lisowski (Univ. Tasmania)

... this volume is a compact, tantalizing excursion through centuries
of medical tradition, in a range of cultures ... it does make a long,
complex and fascinating history accessible to medical professionals
and students of Chinese history who may be tempted to delve further
into this rich and interesting field.
Karen Minden
American Journal of Chinese Medicine, 1994
All this scientific information should be a valuable asset to medical and research
scientists working on the bioactive components of natural products.
Readership: Medical and research scientists interested in bioactive components
of natural products.
216pp
981-02-3639-5
Pub. date: Apr 1996

US$48 33
Pub. date: Oct 1998

US$48
33
If you want a concise, easy-to-read, easy-to-absorb summary of events

and trends from the 29th century BC to the present, this compact
book will comfortably and quickly answer many questions.
American Journal of Acupuncture, 1994
Volume 2
Contents: Part 1: Chinese Medicine: An Overview

of Its Concepts and History; Part 2: Areas Influenced
by Chinese Thought; A Brief History of Medicine
in Japan; A Brief Note on the History of Medicine
in the Islamic World; A Moment of Reflection;
Further Reading; Glossary of Chinese Characters;
Subject Index; Author Index.
Northeast Asia Part II

edited by Paul P H But (The Chinese Univ. of HK), Takeatsu
Kimura (Daiichi College of Pharmaceutical Sci., Japan), Ji-Xian
Guo (Shanghai Medical Univ.) & Chung Ki Sung (Chonnam Natl
Univ., Korea)
Readership: Students of health science, medicine,

social science, history of science, East Asian
philosophy, Chinese and Japanese studies;
practitioners of alternative medicine and Chinese
This second volume of a series of books continues

with the objective of collating relevant information
for showing the differences and similarities of
traditional folk medicines practiced around the
world. It features 200 of the most frequently used
medicinal plants in Northeast Asia as selected by
the international editorial board.
medicine; health practitioners;

academics; and the general public.
116pp
Pub. date: Apr 1997
981-02-2717-5
US$48 33
981-02-2803-1(pbk)
US$21 14
Readership: Medical and research scientists

interested in bioactive components of natural
products.
248pp
981-02-3130-X
Pub. date: Aug 1997

US$48 33
Medical Science
24
G eneral
THE STORY OF INTERFERON
FORTHCOMING
The Ups and Downs in the Life of a Scientist

by K Cantell (Helsinki, Finland)
BIOCERAMICS 11
Proceedings of the 11th International Symposium on
Ceramics in Medicine
New York University, USA
5 8 November 1998
edited by R Z LeGeros & J P LeGeros (New York University)
The Finnish doctor Kari Cantell is one of the

scientists to whom the development of the drugs
called interferons can be attributed. Interferons
have achieved an important place in the
treatment of cancer, viral infections and multiple
sclerosis. In the 1960s Cantell and his coworkers
developed a method for the preparation of
interferon in white blood cells. During those
years, most of the global production of interferon
took place in Finland and the vast majority of
the clinical studies in the world employed Finnish
interferon.
This volume is a compilation of the invited and contributed papers

presented at the 11th International Symposium on Ceramics in Medicine.
The topics covered include: bioinert biomaterials (alumina, zirconia),
bioactive materials (calcium phosphates, bioglass), composites (polymer
ceramic, ceramicceramic), coatings on dental and orthopedic implants,
cements; cellmaterial interactions in vitro; tissue response; biometrics;
tissue engineering.
The book will prove to be invaluable to materials scientists, bioengineers,
molecular and cellular biologists, bone biologists and clinicians
(physicians and dentists).
The book will give the reader a glimpse of the world of science; how research
is carried out in the laboratory and the clinic; how the mind of the scientist
operates and how he experiences success and failure; how warm friendships
and bitter conflicts develop between investigators; how the involvement of
money and politics harms as well as helps research.
Contents: (1) Bone Biology: General; (2) Bioceramics Present and Future;
(3) Bioceramics: Preparation and Properties: Alumina, Zirconia; Calcium
Phosphates; Bioglass; Composites; Coatings; Cements; (4) Cells and
Bioceramics Interactions In Vitro; (5) Tissue Response to Bioceramics;
(6) Biomimetics, Tissue Engineering, Growth Factors, Drug Delivery:
Biomimetics; Tissue Engineering and Growth Factors; Drug Delivery;
(7) Clinical Applications: Dental Applications; Medical Applications;
(8) Methods: Special Preparations and Analysis: Surface Modifications
of Implant; Special Preparations and Analytical Techniques; (9) Author
Index; Subject Index.
The Interferon Story is a richly rewarding book written for ordinary people
without a basic knowledge of biology or medicine. It can be read as a
thriller describing the struggle of scientists against the most feared diseases
of mankind.
Readership: Scientists in various fields of biological sciences and medicine
and laymen.
Readership: Biomaterial scientists.
808pp (approx.)
981-02-3701-4
252pp
981-02-3148-2
Pub date: Oct 1998

US$148 94
Pub. date: May 1998

US$22 15
J ournals
ASIA-PACIFIC BIOTECHNOLOGY
NEWS (APBN)
Preimplantation Genetic Diagnosis: Japan

approves Technique
The First and Only weekly report on Biotechnology Development in

Asia-Pacific
6th Pacific Rim Biotechnology Conference and

Expo 98 Meets in Hong Kong SAR
R & D Faces Cutbacks in Asia
Thailand Seeks IRRIs Help Against Patenting

of Jasmatic Rice
With the rapid increase in the application of biotechnology in the food,

agricultural, pharmaceutical and health care industries in the Asia-Pacific
region, Asia-Pacific Biotech News (APBN) aims to provide you with the
latest news on biotechnology in the region. The wide range of topics
covered includes:
Taiwan Establishes Second Science Park

Thai Rubber Industry Benefit from Indonesias
Crisis
New government policies and regulations
Transgenic Fluorescent Fish
Company profiles, corporate deals and industry trends
A New Heat Stable Phytase from Korea Soil
New product developments and patents
Approved Biotechnology Related Projects Under the Industrial Support

Fund (1998/1999) in Hong Kong
Scientific breakthroughs, new biotech techniques, technological updates

and new drugs
ISSN: 0219-0303
Profiles of scientists and research institutions
English edition (print)
Features of the weeks most important events

Calendar of biotech and biotech-related seminars and conferences
US and Europe news (Chinese version)
Articles featured previously include:

Patent Law and the Development of Biotechnology
Population Control in the 21st Century: China Braces Itself for the
Challenge
Medical Science
Asia-Pacific Biotech News (Vol. 3/1999)
English edition (print & electronic)
US$225
Chinese edition (print) (within China)
US$44
Chinese edition (print & electronic) (within China)
US$50
Chinese edition (print) (outside China)
US$94
Chinese edition (print & electronic) (outside China)
US$112
The frequency for this publication is fortnightly
25
US$188
J ournals
HAND SURGERY (HS)
An International Journal Devoted to Hand and Upper Limb Surgery and Related Research
Journal of the Asia-Pacific Federation of Societies for Surgery of the Hand
AIMS AND SCOPE

Hand Surgery is an international journal, devoted to injury and disease of the hand and upper limb and related research.
The journal has been established to represent the thoughts and experiences of hand surgeons within the Asia-Pacific
region. The journal publishes scientific articles, including case reports, articles on surgical techniques, letters to the Editor,
and information regarding meetings and education programmes. The editorial board is drawn from hand surgeons of
high standing throughout the world. The journal will accept submissions in English from all countries and will encourage
contributions worldwide. It is intended that Hand Surgery reach the high standards attained by the British and European,
and American volumes of The Journal of Hand Surgery, and that these three journals complement each other.
The editors invite the support of hand surgeons and medical institutions throughout the world and hope that you will
join with us in ensuring the success of this publication.
Some Published Papers

Vol. 3, No. 1 (Jul 1998)
End-to-Side Nerve Suture in the Non-Human
Primate (U Mennen)
End-to-Side Nerve Suture in the Human
Patient (U Mennen)
Treatment of Chronic Ulnar Wrist Disorders
(H Ono)
Arthroscopic Suturing of Ulnar Avulsions
(Type 1-B) of the Triangular Fibrocartilage
Complex of the Wrist (L De Smet)
Stabilization of the Distal Ulna by Extensor
Carpi Ulnaris Tendodesis After HemiresectionInterposition Technique (K Masada)
Herbert Screw Fixation for the Treatment of
Scapholunate Ligament Rupture (S Filan)
Anterior Interosseous Nerve Syndrome (T M Tsai)
The Etiology of Kienbock's Disease A HistoPathological Study (G Simank)
Finger Tip Injuries (W B Conolly)
Using Local Flaps for Fingertip

Reconstruction (T M Tsai)
Finger Reconstruction with Volar
Advancement Flap Using V-Y Closure (K Murata)
Free Microsurgical Toe Pulp Flap (G Foucher)
A New Classification of Lunate Necrosis
(M Schiltenwolf)
Melorheostosis of the Hand: A Comparative
Review (J M Wiater)
Old Unreduced Dislocation of the InterPhalangeal Joint of the Thumb (H Patankar)
Simultaneous Dorsal Dislocation of Double

Joints in a Finger. A Report of 2 Cases M Ishizuki)
Irreducible Volar Dislocation of the Proximal
Interphalangeal Joint: 2 Case Report (K Masada)
Magnetic Resonance Imaging of Epithelioid
Sarcoma in the Forearm, A Case Report (T Ozaki)
Bilateral Supracapular Entrapment Neuropathy.
A Case Report (T M Cooper)
Triggering Caused by Complete Transection of
the Flexor Digitorum Superficialis Tendon. A
Case Report (A Gupta)
ISSN: 0218-8104 Vol. 4/1999 2 Issues
Customers from Asia Pacific and Australasia

(except Hong Kong and China), please pay
in Singapore Dollars (S$).
Annual Subscription Rates

For airmail, please add
Customers from the rest of the world (including

Hong Kong and China), please pay in US$.
PRICE INFORMATION
US$81
US$11
S$125
S$17
JOURNAL OF MUSCULOSKELETAL RESEARCH (JMR)

AIMS & SCOPE
Journal of Musculoskeletal Research is an international interdisciplinary journal aimed at publishing up-to-date contributions
on clinical and basic research in the musculoskeletal system. Research into the musculoskeletal system has grown
tremendously in the past few decades. Meanwhile, several outstanding journals in the field have appeared, but with
a different emphasis and objective. With the growing number of studies in the field, the review process has become
increasingly longer. We hope this journal will serve as a new forum for both scientists and clinicians to share their
ideas and the results of their studies.
Journal of Musculoskeletal Research explores all facets of musculoskeletal disorders, with emphasis on both the clinical
and basic aspects of study. It covers the fields of orthopedics, neurology, rheumatology and rehabilitation. The method
of study used can be clinical studies, molecular biology, biomechanics or biomaterial research. Published on a quarterly
basis, the journal publishes review articles, original articles, technical notes and case reports.
Some Published Papers

Vol. 2, No. 3 (Sept 1998)
Clinical and Radiological Results of PLIF for
Degenerative Spondylolistheis (T Yamamoto
et al.)
Radiological Factors Influence Clinical Outcomes
in Posterolateral Fusion for Unstable Lumbar
Spine (M Kawakami et al.)
CPM on Meniscal Regeneration and Maturation
After Meniscectomy in Rabbits (S-S Kim &
M-S Moon)
Effect of Bone Marrow Blood Injection Into
Delayed Fracture Union and Non-Union Gaps
on Callus Formation (M-S Moon et al.)
The Importance of the Sagittall Plane in
Biomechanical Analysis of the Hip (T Quesnel

et al.)
How to Define the Contact Point of the Tibiofemoral Joint of the Prosthhesis in the In-Vitro
Biomechanical Testing (C-K Cheng et al.)
A Comparison of the Compressive and Shear
Stiffness of Periarticular Osteophytes, Hyper-
trophic Femoral Intercondylar Notch and

Normal Articular Cartilage (T O Alonge,
O O A Oni & G J Morrison)
Posterior Complex Contribution on Compression
and Distraction Cervical Spine Behavior:
A Finite Element Model (S Kumaresan,
N Yoganandan & F A Pintar)
ISSN: 0218-9577 Vol. 3/1999 4 Issues
Customers from Asia Pacific and Australasia

(except Hong Kong and China), please pay
in Singapore Dollars (S$).
Annual Subscription Rates

For airmail, please add
Customers from the rest of the world (including

Hong Kong and China), please pay in US$.
PRICE INFORMATION
Medical Science
26
US$126
US$16
S$195
S$25
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THE NEUTROPHILS: NEW OUTLOOK FOR

RECENT ADVANCES IN PSORIASIS: THE

edited by Dmitry I Gabrilovich (Vanderbilt University)

by Barbara S Baker (Imperial College School of Medicine,

This invaluable volume, written by group of internationally established scientists,

Contents: Molecular Events in the Activation of Neutrophils; Oxidative Burst

Readership: Postgraduate students in immunology, biochemistry and cell/

Published by Imperial College Press and distributed by World

Readership: Researchers in immunology and dermatology.

Pub. date: Autumn 1998

World Scientific Series in 20th Century Biology Vol. 4

Published by Imperial College Press and distributed by World Scientific

HEPATITIS B AND THE PREVENTION

This important book comprises a narrative account of research on the

MOLECULAR BIOLOGY OF HUMAN

Research in his laboratory resulted in the discovery of HBV and the

Hepatitis A and B viruses have infected nearly half

There are now national HBV vaccination programs in more than 70

Contents: Hepatitis A Virus; Hepatitis B Virus; Hepatitis Delta Virus; Hepatitis

Readership: Students in human biology and researchers in virology,

Readership: Virologists (medical/non-medical) and molecular biologists.

Pub. date: Spring 1999

Pub. date: Jun 1998

Published by Imperial College Press and distributed by World Scientific

Pub. date: Autumn 1998

World Scientific Publishing

Molecular Mechanisms in Disease and Novel Strategies for

The Science and Culture Series Medicine

The book covers both the molecular

This volume focuses on novel developments in our basic understanding

Contents: Molecular Biology of Hepatitis B Virus: Replication of the

Readership: Molecular & cell biologists and general practitioners.

World Scientific Series in 20th Century Biology Vol. 2

A PORTRAIT OF THE IMMUNE SYSTEM

Readership: Molecular biologists, immunologists and microbiologists.

Pub. date: Autumn 1998

Pub. date: Jul 1998

Published by Imperial College Press and distributed by World

Pub. date: Dec 1996

World Scientific Publishing

SELF-ASSESSMENT FOR THE MRCP:

HIV AND THE EYE

by Barbara Jane Bain (Imperial College School of Medicine, St.

edited by Susan Lightman (Moorfields Eye Hospital, UK)

This invaluable book has been written specifically

Contents: Current Management Approaches in HIV (S Ash); HIV Infection and

Published by Imperial College Press and distributed by World Scientific

Readership: Students preparing for examinations for college physicians,

Pub. date: Apr 1998

COLOUR ATLAS OF OPHTHALMOLOGY

Published by Imperial College Press and distributed by World Scientific

Once in a long while a specialist writes a

SCIENCE IS NOT A QUIET LIFE

This book is lavishly illustrated entirely with

Contents: Diffraction Without Tears: A Pictorial Introduction to X-Ray Analysis

Contents: Examination; Lid, Lacrimal Apparatus and Orbit; Conjunctiva, Sclera

Readership: Biochemists, chemists, medical researchers and molecular biologists.

Pub. date: Jan 1998

Readership: Medical students and medical practitioners.

Pub. date: Autumn 1998

Pub. date: Aug 1995

World Scientific Publishing

Eye Surgeons Solution to Mass Blindness

A Practical Guide to Disorders of the Eyes and Their Management