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Chronic Organ Dysfunction

2015713

Common

COPD




CHFCOPDLCCKD

 DALYdisability-adjusted life year


 WHO

10/2/12

10/2/12

Common Disease

Chronic Organ Dysfunction

Chronic Heart Failure

Chronic Pulmonary Disease


COPD

DPC

Chronic Liver Disease


NAFLD/NASH

At risk

Chronic Kidney Disease


DMHT

Chronic Brain Disease


CHF

CPD

Stage

CLD

Stage

CKD

CBD

Stage
StageCOD
StageStage1

Common

ACCCA
ACCCC

At risk



CODHTDMDL

Basal Change



COD

Clinical symptom

Discomfort/Discompensated




a
a


Stage2

Endstage



RAS


Advance care planning

illness trajectory

ACP

SPSS
ICF

Patterns of Functional Decline at the End of Life.JAMA. 2003;289(18):2387-2392

COD

CHF
CPD
CLD
CKD
CBD

SHFM
BODE index
MELD, CLIP score
CRIB
FAST, MRI, ADEPT

http://www.zaitakuiryo-yuumizaidan.com/data/file/data1_20110516101021.pdf

SHFM

COPDBODE index
(FEV)
(6)
(MRC)
BMI)

10
34

Seattle Heart Failure Model


https://depts.washington.edu/shfm/

CLIP score

Discrimination Value of the New Western Prognostic System (CLIP


Score) for Hepatocellular Carcinoma in 662Japanese Patients.
(HEPATOLOGY 2001;
34:529-534.

The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity


Index in Chronic Obstructive Pulmonary Disease

CKDCRIB

Prediction of ESRD and Death Among People With CKD: The Chronic Renal Impairment in
Birmingham (CRIB) Prospective Cohort Study. Am J Kidney Dis. Dec 2010; 56(6-2):
10821094.

StageK/DOQI (Kidney Disease Outcomes Quality Initiative)

ADL

Palliative Prognostic Score

()

COD

Multimorbidity

QOL
!

QOL, etc.

Common
HTDMObesityIHD

ABCDE+III+QRST
E
Ion & fluid:
Insulin & nutrition
QQOLADL()
R:()
S:()
T:()


QOL


START/STOPP/BEERS

Managing patients with multimorbidity in primary care. BMJ. 2015
http://cmj.publishers.fm/


System holarchy(Hierarchy of holons

Kurt C. Stange. A science of Connectedness.


Ann Fam Med 2009 7 387-394

1
2
3
0.8

Probability

FIM

MNA.SF.score

1.0

3
2At
At risk
1

0.6

0.4

0.2

QOL

0.0
0

10

20

30

40

50

survival.duration

Log-rank)

p0.102

(Log-rank trend)

p0.049

COPD

QOL

400ml

HOT
BiPAP

COPDCHF

Generalist masters.

COPD

200ml/

11kg
22kg
43kg

http://www.zaitakuiryo-yuumizaidan.com/data/file/data1_20110516101021.pdf

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