9/16/2015

What is the best method of removing solvents like chloroform, THF, dichloromethane without using a rotary evaporator? - ResearchGate
6
HOME

PUBLICATIONS

QUESTIONS

JOBS

Search

You are using an outdated version of Chrome which is not supported by ResearchGate anymore. For a faster, safer browsing experience, upgrade your browser now.

Follow this question

Boopathits Boopathits
Amrita Vishwa Vidyapeetham

Answer this question

What is the best method of removing solvents like

chloroform, THF, dichloromethane without using a
rotary evaporator?

QUESTION FOLLOWERS (9)

I want to remove the solvents from my product in acid and base medium. If I use
the rota evaporator it means the pump gets affected. Is there any solution for this
problem?
TOPICS
Rotary Evaporator

Rota-Vapour

Rotary Evaporation

Chloroform

1378

Views
Followers

Answers

Solvents

Organic Synthesis
May 20, 2014 Flag

Share

Doddappa Anekal
Gulbarga University

/0

Ask a question

Questions matching your expertise

ALL ANSWERS (8)

Tyson Francis Belz

8.45 12.87 University of Melbourne

Try remove the solvents under nitrogen

How do I remove excess Polyhydroxymethylsiloxane

from the final product?

1 answer added

1 / 0 May 20, 2014

Is there any plant that work against hepatitis and

toxicity is near to Class 5?

Adel Amer

76.84 132.39 Alexandria University and Taibah

1 answer added

University
You can use air to blow the solvent away [Have your product in an open
beaker and put it in-front of a fan]

Preparation of titanium trialkyl compounds?

New

Be the first to answer

Good luck
May 20, 2014

Pratap Subhashrao Patil

Zhunan, Taiwan

22.53 31.43 Saviorlifetec Corporation,

You can try using air or nitrogen to blow your solvent away but one
trouble will the moisture or water that accumulates in this process...
If you want to avoid the distillation using rota to protect the pump, then
how about simple distillation?????
I still think rota-evaporation is most convinient..If your cooling is good, I
think pump will be ok..If you can't use low temperature cooler for the rotacondenser, check if you can use ice-water circulation..
May 20, 2014

Yuxing Huang

7.48 7.95 Universiteit Utrecht

Blow them away by gentle N2 flow. Or add a cold trap between the

https://www.researchgate.net/post/What_is_the_best_method_of_removing_solvents_like_chloroform_THF_dichloromethane_without_using_a_rotary_evaporator

1/2

9/16/2015

What is the best method of removing solvents like chloroform, THF, dichloromethane without using a rotary evaporator? - ResearchGate
rotarvap and the pump.
May 20, 2014

Ivan Gitsov 37.04 297.2 State University of New York College of

Environmental Science and Forestry
You should install a cold trap between the pump and the rotary
evaporator. Use acetone and dry ice (solid CO2) in the dewar vessel of
the cold trap. This will create a temperature around - 78C, which is
sufficient to trap the THF and the chloroform. If you want to eliminate any
passing vapors use liquid nitrogen in the trap. This would be the fastest
and the most efficient way of drying your product while preserving the oil
in your vacuum pump.
May 21, 2014

Alaa J Mahrath

22.59 2.99 University of Babylon

I a agree with Ivan Gitsov comments .the solvent will trap in the vessel
before reaching to the pump .
May 21, 2014

U B Rao Khandavilli

16.05 27.52 University College Cork

Grind your compound to fine powder. Keep it in drying oven just above
the boiling point of the solvent you used. Take the compound in middle
and grind it once again to make sure total solvent has gone. Do it 2-3
times. Probably you'll get solvent free material.
Jun 4, 2014

Boopathits Boopathits Amrita Vishwa Vidyapeetham

thanks
Sep 30, 2014

Doddappa Anekal Gulbarga University

Enter your answer

Add your answer

20082015 researchgate.net. All rights reserved.

About us Contact us Careers Developers New s Privacy Terms

| Advertising Recruiting

https://www.researchgate.net/post/What_is_the_best_method_of_removing_solvents_like_chloroform_THF_dichloromethane_without_using_a_rotary_evaporator

2/2