Neural Signal Processing

ELEC 548 Fall 2015

Tuesday/Thursday 09:25AM - 10:40AM
BRC 284

are you in the right room?

How does the brain represent and process
informaon?

How can we (experimenters) process and
understand the signals that we record from
the brain?

introductions

Instructor
Caleb Kemere
Research interests: decoding/
interacng with neurons in awake
and behaving animals
Oce: BRC 727

Course Asst.
Eenne Ackermann
Qianli Yang

prerequisites

Excitement about the brain

Basic probability (random processes)

Linear algebra (comfortable with matrix/
vector mulplicaon and concepts)

Matlab or other programming
Beware it will get harder!

syllabus

Oce hours
Websites
Textbooks
Expectaons:

Grading
Homework (where/when)
Exams
Co-working policy
Absences sll responsible

syllabus

Oce hours MW 9-10 AM @ RMC Coee House

make an appointment!
Websites
Textbooks
Expectaons:
Grading
Homework (where/when)
Exams
Co-working policy
Absences sll responsible

syllabus

Oce hours
Websites
Textbooks
Expectaons:

DSP website (search [rice elec 548])

assignments, lecture notes
hp://dsp.rice.edu/courses/elec548

Owlspace closed content, data
Grading
sets, forums, e-submission of HW
Note - if youre not enrolled, we
Homework (where/when)
need to give you owlspace access!!
Exams
Co-working policy
Absences sll responsible

syllabus

Oce hours
Websites
Textbooks
Expectaons:

Grading
Homework (where/when) Look on owlspace/google!
Exams
Co-working policy
Absences sll responsible

syllabus

Oce hours XX% - Homeworks (4 - 8)

XX% - Final Project
Websites
XX% - Final Exam
Textbooks
Expectaons:
Grading
Homework (where/when)
Exams
Co-working policy
Absences sll responsible

class vote: homework / exams

A Homework counts more

B Exams count more
C Balanced approach

class vote: project / final exam

A Final exam
B Final project
C Both

syllabus

Oce hours Turned in by 5pm on due date

(late policy).
Websites
Submit scanned assignment on
Textbooks
owlspace or paper version to
Expectaons: Prof. Kemeres oce.
Grading
Homework (where/when)
Exams
Co-working policy
Absences sll responsible

syllabus

Oce hours HW work in groups, but everyone

turns in their own copy.
Websites
Exams per-exam policy (honor
Textbooks
code!)
Expectaons:
Grading
Homework (where/when)
Exams
Co-working policy
Absences sll responsible

syllabus

Oce hours
Websites
Textbooks
Expectaons:

Grading
Homework (where/when)
Exams
Co-working policy
Absences youre responsible

syllabus

Calendar
Homework approximately every 2 weeks
No class (potenally oponal reviews?):
October 14 (midterm recess)
October 16
November 18, November 20
November 27 (Thanksgiving Break)
Last lecture: December 4
Finals: December 10-17

other classes of interest

Intro to Neuroengineering (ELEC 480)

COMP/NEUROSCIENCE/NEURAL ENGNR (ELEC 481)
Fund. of Cellular/Molecular Neuro (BIOC 3/585)
Theorecal Neuroscience I & II (CAAM 415 & 416)
Fund. Nerve and Muscle Electrophys. (ELEC 481)
Sensory Neuroengineering (BIOE 4/592)
Neural Networks and Informaon Theory (ELEC 502)
Other neuro @ BCM
Data Mining and Stascal Learning (STAT 640)
Stascal Machine Learning (COMP 540)
Computer Vision (ELEC 547)

big picture

Why do Neural Signal Processing
Assisve/reparave
Intervenonal/treatment
Pharmacology development
Neuromorphic systems/circuits
Basic science

What is neural signal processing, actually?

assistive

interventional

pharmacology

neuromorphic

Neural Signal Processing IRL

braingate

memory traces

Deep brain stimulation

canabinoid example

Robbe, Buzsaki 2009

SpiNNaker project

Asynchronous-connected chips model ~1000
neurons ea.. Connect 50,000 chips together?

hp://spectrum.ieee.org/compung/hardware/lowpower-chips-to-model-a-billion-neurons

Neural Signal Processing, Actually

Encoding model => Decoding algorithm

Kalman Filter:
hand posion (gaussian)
neural signals (gaussian)

objectives for class

Students are comfortable with neural data in
many dierent forms, including spikes
measured intracellularly, extracellularly, opcally,
and LFP/EEG.

Students are comfortable building generave
models that describe neural acvity either from
rst principles or using experimental data.

Students are comfortable using generave
models to opmally decode underlying
informaon from neural acvity.

Schedule

Introducon to basic neuroscience

Characterizing/modeling spike trains (point
processes)

Classicaon (maximum likelihood)

Clustering

Dimensionality reducon (latent variable models)

Hidden markov models (latent variable models)

Decoding (connuous latent variable models)

Characterizing/modeling LFP (spectral analysis)

more logistics

Printed slides?