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EpiCast Report: Ankylosing Spondylitis Epidemiology Forecast Global Share and Size, Trends,
Growth, Analysis and Forecasts, 2015 to 2024

EpiCast Report: Ankylosing Spondylitis - Epidemiology Forecast to 2024

Summary
Ankylosing spondylitis (AS) - a systemic, chronic, and progressive inflammatory arthritis, is the prototype
of a family of related disorders known as seronegative spondyloarthritis (SpA) and one of the most
common rheumatic diseases across the globe. AS primarily affects the spine and sacroiliac (SI) joints and
progresses into severe inflammation that fuses the spine, leading to permanent painful stiffness of the
back. AS that occurs before any structural changes in the spine is referred to as non-radiographic axial
spondyloarthritis (nr-axSpA) which is the early stage of AS. Some of non-radiographic axial
spondyloarthritis progress to AS and some do not.
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Scope
- The Ankylosing Spondylitis EpiCast Report provides an overview of the risk factors, comorbidities, and
global trends for ankylosing spondylitis (AS) in the seven major markets (7MM) (US, France, Germany,
Italy, Spain, UK, Japan). It includes a 10-year epidemiological forecast of the diagnosed prevalent cases
of ankylosing spondylitis segmented by sex, age (in ten-year increments beginning at 15 years and

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ending at =65 years), and diagnosed prevalent cases of non-radiographic axial spondyloarthritis, and
diagnosed prevalent cases of AS segmented by HLA-B27 seropositivity status in these markets.
- The ankylosing spondylitis epidemiology report is written and developed by Masters- and PhD-level
epidemiologists.
- The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis
of disease trends in the 7MM.
Table of Contents 4
1.1 List of Tables 6
1.2 List of Figures 7
2 Introduction 8
2.1 Catalyst 8
2.2 Related Reports 9
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3 Epidemiology 10
3.1 Disease Background 10
3.2 Risk Factors and Comorbidities 12
3.3 Global Trends 13
3.4 Forecast Methodology 17
3.5 Epidemiological Forecast for AS (2014-2024) - Base Scenario 31
3.5.1 Diagnosed Prevalent Cases of AS 31
4 Appendix 48
4.1 Bibliography 48
4.2 About the Authors 53
4.3 About GlobalData 56
4.4 About EpiCast 56
4.5 Disclaimer 57
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