MAY 25 SUN 2014

/2014()!
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1.ADM
? P.203 12-1 or P.209 12-3
(A)
(B)
(C)
(D)

1.:

2.:

3.:


4.

5.:

6.

2.CType 2 DM : P.205
A
BDM
Cinsulin(insulin)
D()

:
1.DCCT
2.2:
3.BTZD? P.96
ACHF
BDM
C
D

4.BUKPDS Pancrean function %? P.13. P19

(A).25%
(B).50%

(C).75%
(D).>90%

5.(!!)170~80%22
6.50%20~30%

5.DType 2 DM
150min? P.29

(A).A1C,CVD
(B). A1C,CVD
(C). A1C,CVD
(D). A1C,CVD

6.(D)CSInsulinP.87
(A).
(B).
(C).

(D).Insulin
(
)
(CS II)

1974(pump)
(0.5~1.0/)( olus dose)
:

7.BDM? P.120
(A).
(B). ()
(C).<1500mg/day
(D).

8.CBMI>25
Type 2 DM?

AA1C>5.7
BHDL<35
CCholesterol>250 (..)
D

2(!)
1.()
2.45

3. (24 Kg/m2)
4.
5./...
6.
A1c<5.7%5.7%~6.4%6.5%
7. (140/90 mmHg )
8.35/ (0.90 mmol/l)/
250/ (2.82 mmol/l)
9.4.0
10.
11.

9.C5.?
(A).,
(B).,
(C).

10.BOmega-6 1.LDL 2. 3.HDL 4.

(A)1+3
(B)1+2
(C)2+3+4
(D)1+2+3

Omega-6

Omega-3

11.DDKA? P.156-167
A()
B (
)
C (
)
D()

12.CDM? P.209211
A
B
C()
D

1.:

2.:

3.:


4.

5.:

6.

13.A 65
Type 2 DM A1C:7.5%Cr:2.2mg/dLALT:25 OAD? P.92

ARepaglinide
BAcar ose
CGlimepride
DMetformin

14.BTG?
(A).HDL
(B).LDL
(C).HDL
(D).LDL

15.D? P.165-166 or P.76

A

B

C
D

:

16.CGDM
OGTT P.245
(A).2~4
(B).4~6
(C).6~12
(D).12~24

17.BDM?P.179
(A)

(B)

(C)
(D)

18.3ROC? P.347
(1)
(2)
(3)
(4)

19.B?
? P.161()
(A)
(B)
(C)

20.B?

(A)Glimepiride
(B)Nateglinide
(C)Metformin
(D)pioglitazone

21.2? P.194
(A)()
(B)()
(C)()
(D)ACEI(ACEIARBs)

22.4Metformin+Acar ose:
(A)
(B)Acar ose
(C)Metformin
(D)Metformin

23.D? P.252
(A)

(B)
(C)
(D)

Jorgen Pedersen
()

24.C
? P.248
(A) BMI:12.7~18.2kg
(B) BMI:11.2~15.9kg
(C) BMI:6.8~11.3kg (:4.5~9.0kg6.8-11.3 kg)
(D) BMI:15.9~20.4kg

GDMBMI

BMI

12.7~18.2 kg

11.2~15.9 kg

6.8~11.3 kg

4.5~9.0 kg

15.9~20.5 kg

20.5~25.0kg

25.D? P.395

(A) (



(B)
(C)
(D)

:
-6

:

:

:
B
B

26.B
?
(A)
(B)
(C)
(D)
(Insulin LisproInsulin AspartInsulin Glulisine)(RI)

1.:
(1)

(2)0.1~0.15//

10~15
2.:
(1)4
(2)

(mg/dl)/36()=()
(3)0.05//=()()
(4)(BI)BI()X10%=()
3.:
(1)

>140mg/dl

(2)

136~153mg/dl


154~180mg/dl

2
>180mg/dl

3
(3)<10

<10

1
11~20

2
>20

3

27.CDM?P5

(A)
(B)
(C)
(D)

(fasting plasma glucose, FPG)

28.A
?
(A)2R(3R
Registration Rell
Regular Review)
(B)
(C)
(D)&

29.DType 2 DM? P.204

(A)
(B)
(C)
(D)

2:
30.CAcar ose: P.98
(A)
(B)30min
(C)
(D)30min

31.C<20/160 (WHO)? P.182

(A)
(B)
(C)
(D)

ICD-9

WHO

20/30~20/60
<20/25

20/70~20/160
<20/70<20/80
()

20/200~20/400
<20/160

20/500~20/1000
<20/400

32.D?
(A)
(B)

(C)
(D)

33.DGli enclamide
Metformin+Acar
(A)
(B)Acar ose
(C)Metformin
(D)Metformin

34.ADM?
(A)
(B)
(C)ACEIB- locker
(D)statin
DM:

1.DMDM

2.AsprinClopidogrelGlycoprotein II /IIIa receptor

3.:B- lockerStatin
4.
DM:

1.DM
2.DM130/80mmHg44%

3.HPSSimvastatin24%CARDSAtorvas
4.

5.

6.:>180mg/dl
35.DDM?P.204
(1)50%
(25%)
(2)3~20%( 4-29% )
(3)4~29%(20-30%)

(4)DM8%(2550%)
:
1.12

2.8%25
3.25%
20~30%4~29%
4.
5.2

36.BDM?P.210
(A)20% (60%)
(B)
(C)(
)
(D)
:
1.
2.

3.
:
4.
5.60%
6.

7.

37.BTZDs? P.97 P.103

(A)
(B)LDL(HDL-C
)
(C)TG
(D)

PPAR-

Rosi
litrzone
HDL-CLDL-CPio
litazoneTG
HDL-C

38.D
(A)

(B)
DM
(C)

(D)




(PDR)




NPDRPDR
39. (B)?
(A)
(B)

(C)
D
:
1.
2.::+:
::
3.

4.

5.
6.:

:0.6/k
/day6:0.7/k
/day16:0.8/k
/day26:0.9
7.
::0.6/k
/day:0.4/k
/day

40.1
(1)Charcot foot
(2)()
(3)

()

1.
2.

(1)15

(2)


(3)5.07

(4) 5.0710
(5)
5.07/
3.

(1)
(2)

(3)
(Char
4.
(1)



(2)


(3)

(4)

41.CDM?
(A) Type 1 DM 1520~30%Microalbuminuria
(B)UKDPS Type 2 DM 1025%Microalbuminuri
(C) Type 2 DM
10%(2.3%)
(D)

1.43%8%

2.201123.6%10.6%CKD

3.11520~30%80%

4.UKPDS21025%5%0.8%
5.
ACEIARB

6.CKDCVD

42.B?
(A):30-300u
/m

(B)24hr:500m

(C) 4hr:10u
/min
(D) 12hr: 250m

43.BHHS: P.163
(A)
(B)HHSDKA
(C)
(D)
(HHS)
1.
(DKA)
2.:
(1)

(2)

DKA3.3mEq/L
=+[0.016x(-100)]

(3)

DKAHHS
50~75m
/dl/hr
(4)
(5)
(6)

44.B
:
(A) MODY1
(B) MODY2
(C) MODY3
(D) MODY4

45.B?
(A)
96hr P.9
(B)
(C)
P.32
(D)

2
1.

(1)
(2)
2~35~7
(3)
15~30
2~4
2.:
(1)

(2)
(3)
150
(4)
3~5
(5)
10
30
(6)50~70%
3:
(1)
46.D?
A.
B.
C.
D.

47.A,?
A
B
C
D

48.B


(A)130

(B)120

(C)150

(D)100

49. (C)?
(A)
(B)
(C)
(D)

50.ABile acid sequestrants

(A) LDL (LDL15-30%)
(B) HDL (HDL 3-5% )
(C) TG ( TG )
(D)
Bile acid sequestrants

51.BTZD? P.96
ACHF
BDM
C
D
52.DM
(A)h-3()
Insulin
(B)
Insulin
(C)
Insulin
(D)

Insulin

53. P.410 P.400

(A) Aspartame
(B) Ome
a-3(-3)TG
(C) Cr
(D)
54.B P.247
(A) Insulin ()
(B) 300AM
(C)
Insulin ()
(D)
62kg/(0.8 kg/)
55.BDM
(1)
6
(2)
6

(3)2

(4)65
51
(A) 2+3
(B) 2+4
(C) 1+3
(D) 1+4
56.BHHS? p162~163
A
BInsulin
C
D

Insulin

57.A

? P
A


B


C

DAlanine(
)

58.D1..-1 receptor blocker

A.
B.
C.

D.

59.DGDM?
A

B
Ctocolytics

D

6~12275

60.C65

::65kg :155cm :160/95 A1C:9.5% BUN:50 C

A. TG<200
B.LDL<100
C.fenofibrte 100mg TID

D.fibrtesttin

ADA
NCEP ATP III

LDL-C<100
CVD<70
LDL-C<100

HDL-C>40()
HDL-C>50()
TG<150

TG<150

Fibrte

2010ACCORDNEJM2TG204mg/dlHDL-C34mg/dlfi

61.
?
()
(
)
()
()

62.OAD?
sulfonylurea
iguanides

-glucosidse inhibitor
repglinide

63.OADOAD
A1.5-2.0u/kg
B.0.5-1.0 u/kg
C0.25-0.50 u/kg
D0.1-0.2 u/kg
2OADs+BI:
BI()NPHInsulin GlrgineInsulin Detemir:

1.10/0.2//


70~130mg/dl

2
2.
1
<100mg/dl
D64.CSIIinsulin?
Aglrgine
Bdetermir
Ccultrlente
Dsprt

65.__%__?
A.50%
B.50%
C.50%
D.50%

66.D?
Aflvonoid
Btriterpine(
)
Clliinse

Dlliin

(Alliin)
(Allinse)
67.DM
?

1.metformin 2.sulfonylure 3.GLP-1 4.rcbose 5.insulin

A.134
B.235
C.234
D.25

D68.?
A.
B.
C.
D.

1.
2.
3.

4.
69.?
A
B
Cmetformin
D

OADsGlibenclmide(Glyburide)MetforminOADs
70.sttin?
LDL-C
TG
HDL-C (HDL)

LDL-C

71.
?
A
B
C
insulin
D

72.A(CSII)?
A.
B.
Cc.type I
Dd.

73.D
?
A.
B.
C.
D.

74.BMicrolbuminuri
?
A

B60
48-60
C
D
ACEI

0.8~1.0g/kg
ACEIARB
ACEIARB

75.DDM

A0-1.8

B1.8-2
C0.6-0.8
D0.9-1.2

0.9~1.2//
:

:0.6/kg/dy6:0.7/kg/dy16:0.8/kg/dy26:0.9

76.DDM? P.235
A

B
C

D

77.BInsulin?
ATG
B

C
D

78.A? P.250
Aeffect

B16-50%
C
D

1.:
(1)




(2)6~9
(3)
(4)


(5)


79.C0.01()
A

B
C
D

0.1()0.2()
20

30
>10DB
()0.2

0.1()
30
>15DB()
()0.2()

0.01()
30
>20DB()
()0.2

80.D
A4000

B10%45001%20-32

CLGA

D4000

4000
LGA

2

4500

81.Bcounter-regultory hormone

A(Cortisol)
BEstrogen
CEpinephine
DGlucgon
:

82.C
Atype 110
B
(mculr edm)
C

D

83.D
AL-Peptide
BProinsulin
CAmylin
DGlucagon
84.BTZDs
A
B
PRAR-
CACT

3
D
2.:
(1)
PPAR-
(2)

85.B
A
BMethyldopa
C

86.B
A
B20mmH

100
CMI
DMI

87.D
A CKD 2
B CKD 3
C50
65 Cr2.0m
/dl CKD 5
D3GFR= 30-59 ml/min

88.AADA ACCLDL-C 100m
/dl

Anon-HDL CH

130m
/dlapo B

90m
/dl

Bnon-HDL CH

200m
/dlapo B

100m
/dl

Cnon-HDL CH

100m
/dlapo B

80m
/dl

Dnon-HDL CH

160m
/dlapo B

130m
/dl

89. D?
APolyol
B

CSorbital

DMicrothombim

90.B1
A
B
C24

D70%

91.B
2

A
B
CSulfurea
D

1030520
1

(D) ?

A. Repa
linide B. Glibenclamide C.Bi
uanide D.

(B)
98m
/dl, ?

A.

B.C.

(B) 3

A.

TG B.HDL C. LDL

(A) ?

A.
B.
C.50-70%

(B) DM

A.()B. .2

(A)type 2 ? (,)

A. LDL>160mg/dl B.

(A)TZD?

A. B. TNF- C.

TZD
http://.cmj.c/content/172/2/213/F6.expnsion.html

(B)DM

A.

B.>20,100

(B)BMI>25,
type 2 ?

A.
B. TC>250 C. A1C>5.7 D. HDL<35

10 (C)A1C 9.5%, BUN 50-60, , (,)

AGlibenclmide B.Metformin C.Acrbose D.

11 (B)
A.Fibrte TGHDL -3 B. -3 TGHDL Ezetimibe
e

C. Ezetimibe LDL TG sti

12 (B)

A.7-15B., C. D.

13 (C)
A.

B.
C.D.

14 (C )ACEI

,brdykinin
,,
A. COB. CO2

C. NO

D. NO2

15 (C)?
1.Lispro 2.Asprt 3. RI 4.NPH
A. 1+2 B. 2+3 C. 1+2+3 D. 2+4

P.122

16 ( B)?
A. (polyol)B.

17 (C ),
A. 5
,BMI B. C.

18 (B)2008ADAACCLDL<100mg/dl, non-HDLpo?
A. non-HDL cholesterol<100,po<80 B. non-HDL cholesterol<130,po<90 C. non-HD
L cholesterol<200,po<100 D.non-HDL cholesterol<160,po<130

non-HDLpo
http://.cponline.org/bout_cp/chpters/v/12mtg/fredrickson.pdf

19 (B)(BPH),?
A. - locker B. 1-blocker C. centrl- gonist D. CCB

20 (D)?
A. B. C. D.

21 (A )?
A. B.
C. D.

22 (B),

P.196

A. Type 230
, 35
B. Type 122
, 27
C. Type

23 (D) ,
A.

B.
DM
C.

D.

24 (C) <20/160 (WHO)? P.182

A. B. C. D.

.DM ptCVDLDL? P.112

Ans70mg/dl

OADInsulin?
AnsRepglinide

HDL? P.117
AnsHMG-CoA Nicin

Amylin ? P.3

AnsB cell

Insulin ??? P.2

DREAM?

? P54

Ans8~12hr

? P48. P65

?DM(1)(2) (3) (4)

LDL
?

DM ?

1.
:

~
45%~65%10%~35%20%~35%

DM~
60%~70%15%~20%10%

2.
4

3.50~60%

4.21

5.

6.

7.(20%)

? P.65

170cm80kg(BMI:)0.5kg
?

:
20/:
25/:55

30/:
40/:

5001000
0.5~1.0
<1600()
l

<>? P.347

Type 2 DM
?

1.

2.15

3.2



4.

NPDR


NPDR
6~12
PDR

3~4
PDR

5.
(
)

l

Chipkin?

DM?

DM? P.120

JNC7ThiazideHydrochlorothiazide(HCTZ)
l

? P226. P.230

l

DM? P.230 P.232

ADA? P.337

(AADE)
1.2.3.4.5.6.7.
l

DKA? P.158

DM P.54

DM?

OAD? Acar ose

Glucophage? P.94

? P.67

l Type.1 CKD P193 :

1.

2.BP3.&HBP
15:
1:

GFR
2:


GFR

3:

4:
GFR

5:GFR<15mL/min

>5mg/dl

l

STOP-NIDDMAcar ose

DM5W

CF

GDM? P246 P.251

? P.224

DM? P.223

GDMIADPSG? P.246

DSHEA? P.66

45.

? P.216

? P.393

1.
2.

3.
4.
l

P.396 P.401

1.

2.
3.
l

? P.78

.<80 mg/dL? P.170

? P.56

25kg 580/100kg 50kg ?

.DM?

Type 1?

5?

70
<>?

Cr ?mg/dLMetformin? P.95

ADA?

2009 USA
?

P.5

P.218

? P.391 P.393

GFR? 100~125

DM?? P.248

Pederson
?

Type 2 DM1-blocker?

Type 2 DM?

DPP

RDA AI UL DRI

DM

24(mg/24hr)
(ug/mgCr)
(ug/min)

<30
<30
<20

30~299
30~299
20~199

300
300

200

()

p30.---- :2
l
l
l
l
l
l
l
l
l
l
l
l

1.

p37 -8::
30
p48.()-2-
p51.:
p67.5
p88-89 :
P100.BYETTA
P111.()
P117-118 NIACIN
P205 ::
P209

P253 .---

:

Type2

()2(!!)
2
2
2
1.
2(concordance)70-90%
290%

22
2

22

2.

2.

Insulin aspart

:Insulin AspartR

28aspartic acidproline

RI(Regular Insulin)Aspart
1.AspartLispro
2.RIAspart
3.AspartLispro

3.

1.
2.
3.
4.
4.ANS

5.

INSULIN

0.5~0.7
6.

DM

:
1.
2.
3.
4.

5.(DASH)

7.

DM

:
~
45%~65%10%~35%20%~35%

DM~
60%~70%15%~20%10%

8.

DM

:
1.12
2.2550%
3.25%
20~30%4~29%
4.
5.2

9.

PEDERSON

Jorgen Pedersen

10. DM

1.:

2.:

3.:


4.

5.:

6.

11.

12. INSULIN
:
1.
2.a
:
1.
2.()(
)

3.(glycogenesis)
4.(glycogenolysis)

5.(gluconeogenesis)()

13. GLIBENCLAMIDE METFORMIN ACARBOSE

14. B CELL
:
1.
2.Amylin~
3.

15. 2010 TYPE 2

16.

17. JUC7
18. DM
19. DM
20. DM(CS2)
(CS II)

1974(pump)
(0.5~1.0/)( olus dose)
:

21. GLARGINE
Insulin Glargine(LantusR)
1.
2.24
3.A21glycinasparagineBarginine

4.
PH=4.0(PH7.4)

5.

6.12Glargine QDNPH QD BID(NPH-Neutral Protamin

7.2GlargineNPH

8.


9.

22. DM
23.

(1)():
Metformin
(2)
:
Thiazolidinediones(TADs):
Pioglitazone(ActosR)

3.
(1)a-

Acar ose(Gluco ayR)Miglitol(GlysetR)

24. BMI25DM
25. DM
26.
27.

ASPIRIN WARFARIN

28. UKPDS TYPE2 B CELL?

29.
30.

31. TZD
32.

INSULIN

33. INSULIN
34. DM

35. 65
65155160/95HBA1C:9.5BUN:50CRE:3.5GOT:40GPT:56
36.

37.

38. TZD
39.

40. ASPIRINDM
41. TYPE2
42. DM
43.

44. DM
45.

ICUINSULIN

46.

47. WHO
48.

CP450CYP2C9

49.
DM
50. DM

/@2014!
/@2014!
/OAD@2014!
/@2014!
/GDM@2014!
/@2014!
/@2014!
/@2014!
/Insulin@2014!
()