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Objective :Anatomy
RESPIRATORY
SYSTEM
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Physiology
Overview
Respiratory
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Express
Diseases
Types of Respiration
The classification depends upon the availability of oxygen and thus it has
been divided into two categories.
(a) Aerobic Respiration: It takes place in presence of oxygen and the
stored food (respiratory substrata) gets completely oxidised into carbon
dioxide and water as end products.
(b) Anaerobic-respiration: It takes place in absence of oxygen and
stored food is incompletely oxidised and instead of carbon dioxide and water
certain other compounds are also formed. This type of respiration is of rare
occurrence but common among micro organisms like yeasts.
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1
fOUR LIFE
External Nares (Nostrils): They are a pair of slit-like openings present on the lower end of
nose.
Nasal Cavity: It is situated between palate and cranium. Nasal cavity is divisible into two
nasal chambers by a nasal septum. Each nasal chamber has three parts.
Vestibule: It is lower small part just above the external nares which is lined by skin and
bears hair as well as oil glands. Hair help in filtering out dust particles from incoming air.
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Respiratory System - 2
The external intercostal muscles connect adjacent ribs. When they contract the ribs are
pulled upward and forward causing further increase in the volume of the thoracic cavity. As
a result fresh air flows along the branching airways into the alveoli until the alveolar
pressure equals to the pressure at the airway opening.
Lung: A pair of conical spongy elastic lungs of pinkish to salty grey colour occur inside air
tight thoracic cavity. Left lung is slightly narrower and longer than the right one. Right lung
has three lobes, left lung has two lobes. Each lobe is divided internally into segments and
segments into lobules. A lobule receives a terminal bronchiole. Terminal bronchiole
produces a few respiratory bronchioles. A respiratory bronchiole give rise to 2-11 alveolar
ducts, each of which ends in an alveolar sac. The latter has a number of small pouches
named alveoli or air sac. Blood capillaries occur on the surface of alveoli for gaseous
exchange.
Diaphragm: It is a membranouus musculo-tendinous partition between thorax and
abdomen. Phrenic muscles attach diaphragm to ribs and vertebral column. Contraction of
muscles straighten the diaphragm to increase thoracic cavity. There are two sets of
Intercostal Muscles: (i) external intercostal for normal inspiration and expiration (ii) internal
intercostal for forceful expiration.
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Respiratory System - 3
The external intercostal muscles connect adjacent ribs. When they contract the ribs are
pulled upward and forward causing further increase in the volume of the thoracic cavity. As
a result fresh air flows along the branching airways into the alveoli until the alveolar
pressure equals to the pressure at the airway opening.
Respiratory System - 4
Expiration
Expiration is a passive event due to elastic recoil of the lungs. However, when a great
deal of air has to be removed quickly, as in exercise, or when the airways narrow
excessively during expiration, as in asthma, the internal intercoastal muscles and the
anterior abdominal muscles contract and accelerate expiration by raising pleural
pressure.
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Respiratory System - 5
OVERVIEW
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Respiratory System - 6
GAS EXCHANGE
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Respiratory System - 7
Regulation of Breathing
1. Breathing is so important that your body will not let you have complete control of it.
2. Breathing is controlled by the medulla oblongata in the lower part of the brain, though,
obviously, you can temporarily suppress this reflex. The diving reflex (not breathing when
your face is submerged particularly in cold water) is found even in babies, and allows them
to be bathed and swim (under supervision) with complete security.
3. Although you can hold your breath for a while, you cannot die this way. You can only hold
your breath until you lose consciousness - then the brain takes control and normal
breathing resumes.
4. The concentration of oxygen in the blood has little effect on breathing rate and you can
suffocate in a low oxygen environment (e.g. on a mountain or in a plane when the
pressurisation fails.)
5. Breathing is controlled by the levels of CO2 and H+ ions in the blood. These are measured
in two places in the neck (carotid arteries) and just outside the heart (aorta). These regions
have swollen areas known as sinuses which also measure blood pressure. Nerves lead from
these regions to the hypothalamus (hind-brain), which controls most aspects of
homeostasis.
Lung Volumes
TABLE 12.1
Volume or capacit~
Definition
lnsplratory reserve
volume (IRV)
3,000 ml
Expiratory reserve
volume (ERV)
1,100 ml
Residual volume
(RV)
1,200 ml
Functional residual
ca paclty (FRC)
2,300 ml
lnsplratory capacity
(IC)
3,500 ml
4,600 ml
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iTyP.ical valu~
500 ml
5,800 ml
Respiratory System - 9