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What are the 7 principal functions of the


skeletal system?

Support, protection, body movement,


hemopoiesis (blood formation), Mineral
storage, hormone production, fat storage

Compact bone

Outer, dense white osseous tissue,


smooth and solid

Spongy bone

Loosely organized osseous tissue


enclosed by compact bone

Diaphysis

Shaft; surrounds marrow cavity

Epiphysis

Ends of a bone; spongy bone

Epiphysis plate

Region of bone growth in children


(hyaline cartilage)

Epiphysis line

Transparent line in adult bone; left after


bone growth ends

Articular cartilage

Hyaline cartilage that caps epiphysis and


facilitates movement between two bones

Medullary cavity

Space filled with either red or yellow


bone marrow

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Red bone marrow

Hemopoietic bone marrow (youth:


entire marrow; adulthood: only skull,
ribs, vertebrae, sternum, pelvis, head
humerus and femur)

Yellow bone marrow

Stores fat

Periosteum

White, double layered membrane;


covers external surface of bone; has
many bloo vessels and nerves and is a
point of tendon attachment

Endosteum

Delicate connective tissue membrane;


lines medullary cavity, trabeculae, canals

Osteoblast

Bone forming cells

Osteocytes

Maintain healthy bone

Osteoclasts

Bone remodeling cells

Osteon

Unit of one central canal and its lamellae

Lamellae

Layers of matrix arranged around a


central canal

Central canal

Blood and nerve supply for living


osseous tissue

Lacunae

Contain osteocytes

Canaliculi

Connections between lacunae containing


cytoplasmic extensions of osteocytes

Endochondral ossification

Process in which bone develops from a


preexisting cartilaginous model

Bony collar

Perichondrium starts producing


osteoblasts around middle of cartilage
model

Primary ossification center

Enlargement and death of chondrocytes


in middle of cartilage model

Vascular invasion

Blood vessels penetrate bony collar and


invade primary ossification center

Primary marrow cavity

Center of model is hollowed out and


filled with blood and stem cells

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Secondary ossification center

Epiphysis of model is hollowed out and


filled with blood and stem cells

Condyle

A rounded knob

Head

The prominent expanded end of a bone,


sometimes rounded

Crest

A narrow ridge

Epicondyle

A projection superior to a condyle

Line

Slightly raised, elongated ridge

Process

Any bony prominence

Protuberance

A bony out growth or protruding part

Spine

A sharp, slender or narrow process

Trochanter

Two massive processes unique to the


femur

Tubercle

A small, rounded process

Tuberosity

A rough surface

Alveolus

A pit or socket

Fossa

A shallow, broad, or elongated basin

Fovea

A small pit

Sulcus

A groove for a tendon, nerve, or blood


vessel

Canal

A tubular passage or tunnel in a bone

Fissure

A slit through a bone

Foramen

A hole through a bone usually round

Meatus

An opening into a canal

Sinus

An air-filled space in a bone

Cartlilage doesn't contain what?

blood vessels and nerves

What is the name of the dense irregular


connective tissue surrounds cartilage?

Perichondrium

Cartilage contains cells called _____


which live in cavities called _____, and
________

Chondrocytes, lacunae, extracellular


matrix

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What are the three types of Cartilage


and examples of where you would find
it?

Hyaline cartilage (Nose, costal and


larynx cartilage)
Elastic cartilage (Ear and epiglottis)
Fibrocartilage (intervertebral discs and
meniscus)

What is the Axial Skeleton?

Cranium, Rib cage, and Vertebral


column

What is the Appendicular Skeleton?

Upper limbs, Lower Limbs, Pectoral,


Pelvic Girdle

Osteogenic cells

Mitotically active stem cells in


periosteum and endosteum

Osteoblasts

Bone forming cells, reponsible for bone


growth; secrete matrix

Osteocytes

Mature bone cells that maintain and


monitor the bone matrix

Osteoclasts

Giant, multinucleate cells for bone


resorption (break down the bone)

Osteon

Structural unit o compact bone (elongate


cylinder)

Concentric lamellae

Hollow tubes of matrix arranged around


one central canal

Central canal

Runs through ceter of osteon; contains


blood vessels and nerves

Perforating canal

Run at right angles to central conal;


conatins blood vessels and nerves

Lacunae

Small cavities that house osteocytes

Canaliculi

Hairlike canals that connect neighboring


lacunae (communication)

Circumferential lamellae

Lamellae that extend around entire


surface of diaphysis

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What is the chemical composistion of


bone?

/Organic components: Cells and


matirx (Flexibility and strength
/Inorganic components:
hydroxyapatites= mineral salts, mainly
calcium phosphate crystals (Hard and
compresssional strength)

Endochondral ossification

process in which bone forms by


replacing hyaline cartilage models

Intermembranous ossification

process in which bone forms from


fibrous membranes

Primary ossification center

region in middle of shaft; endochondral


ossification begins here

Bone collar

forms around diaphysis of hylaline


cartilage model

Secondary ossification center

appear in epiphyses after medullary


cavities have formed in diaphyses

Epihyses ossify

Plates and articular cartilages

Interstitial growth

Bone growth in lngth of long bones at


epiphyseal plates

Appositional growth

bone growth in width of bones


(throughtout life)

What three hormones regulate bone


growth?

Thyroid hormone, Growth hormone and


Testosterone/ Estrogen

What are the two hormones that


regulate blood calcium levels?

Parathyroid hormone and calcitonin

Calcitonin

Lowers blood calcium levels

Wolff's Law

Bone grows or remodels in response to


demands/stress placed on it.

What are the four stages of Bone


Repair?

1. Hematoma forms (mass of clotted


blood)
2. Fibrocartilaginous callus forms
3. Bony callus forms
4. Bone remodeling occurs

The integumentary system is composed


of ___ and its ___, ____ and ____.

Skin, glands, hair and nails

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What are the 6 functions of the skin?

Protection, Body Temperature


Regulation, Making Vitamin D,
Cutaneous Sensation, Blood Reservoir,
and Excretion through sweat.

The two layers of the skin are called ___


and ___.

Epidermis and dermis

Stratified keratinized squamous


epithelium is found in the ___.

Epidermis

Dense irregular and elastic connective


tissue with blood vessels, nerves,
receptors, etc. ____

Dermis

Subcutaneous layer, not actually part of


the skin

Hypodermis

Adipose and loose connective tissue with


blood vessels and nerves

Hypodermis

Stratum basale

Lowest layer of the epidermis

The stratum basale is a single layer of


what cuboidal main cell type that is
firmly attached to the dermis?

Keratinocytes

The stratum basale sits on the ___ and


is ___ active

Basement membrane; mitotically

Stratum corneum

Upper layer of the epidermis that


contains up to 20-30 layers of dead,
flattened keratinocytes

Hypodermis

Subcutaneous layer is not part of the


skin and binds the skin to underlying
muscles.

What are the 3 components of the


hypodermis?

loose connective tissue (areolar),


adipose tissue, blood vessels and nerves

What are the 3 main parts of the hair?

Shaft, root and bulb

What supplies blood for nutrition of


cells growing in the bulb region?

hair papilla

What contracts involuntary when you're


scared or cold?

Piloerector muscle

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Nails are ______.

Scaly cells that are heavily keratinized

What is resposible for nail growth?

Nail matrix

What are the 3 types of cutaneous


glands?

Sebaceous, sudiferous, ceruminous

Sebaceous gland

associated with hair follicle; secretes


sebum; lubricates and waterproofs the
stratum corneum (oil)

Eccrine sweat gland

Widely distributed over body; cooling

Apocrine sweat gland

Open via hair follicle; in axillary and


pubic regions; and odoriferous

Ceruminous gland

Found in the external ear; water and


bacteria repellent; secretes cerumen
(wax)

Which stratum consists of several layers


of kerationcytes united by desomes?

Spinosum

Which stratum is thin, about 4 to 6 lyers,


cells accumulate keratin granules and
lamellar granules, which make the skin
water resistant?

Granulosum

Which stratum will you only find in


thick skin, few rows of flat, dead
keratinocytes?

Lucidum

The statum corneum consits essentially


of flat membranous sacs filled with
what?

Protein

Apoptosis

Controlled cellular suicide

What are the cells of the dermis?

Fibroblasts, Macrophages, and


occasionally mast cells and WBC (White
Blood Cells)

The dermis provides what for the


epidermis?

Blood supply

What does the dermis contain?

Nerve fibers and lymphatic vessels

The dermis contains what epidermal


derivatives?

Hair follicles, oil and sweat glands

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What are the two layers of the dermis?

Papillary layer and reticular layer

Papillary layer consists of what?

Loose Areolar connective tissue with


collagen and elastic fibers

The reticular layer is strong and resilient


and is made of what?

Dense irregular connective tissue which


also contains lots of collagen and elastic
fibers.

The papillary layer has dermal papillae


which form the base of what?

Dermal ridges

Skin marrkings include what?

Cleavage lines (Important for surgeons)


and Flexure lines (Hand)

The reticular layer is the leather of the


skin and if its fibers are torn can cause
what?

Scars

What pigments contribute to skin color?

Melanin, Carotene, and Hemoglobin

Blue skin color, due to low _____ of


hemoglobin

Oxygenation

Red skin color, due to fever,


hypertension, _____, allergy

Erythema

White skin color, due to anemia, low BP,


fear, anger

Pallor

Yellow skin color due to _____ disorder

Jaundice

What Epidermal tissue sheath folds


down from epidermis into dermis?

Hair follicles

What type of cutaneous gland contains


the eccrine and apocrine sweat glands?

Sudoriferous gland (Sweat)

Mammary glands

Modified apocrine gland in breast tissue


(secrete milk)

What does a keratinocyte?

A cell that produces keratin, the fibrous


protein that helps give the epidermis its
protective properties.

What is a melanocyte?

A cell that produces the pigment


melanin, protection against UV damage.

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What are the layers of the stratums from


superficial to deep?

Stratum corneum, Stratum lucidum,


Stratum granulosum, Stratum spinosum,
and Stratum basale

The dermal papillae are what?

Indentions in the epidermis that


contain: capillary loops, nerve endings
(pain receptors) and touch receptors.

Meissner's (tactile) corpuscle are what?

Touch receptors

Pacinian (lamellated) corpuscle

Larger receptors for vibration and


pressure.

Eponychium

Nail cuticle

What are the three types of skin cancer?

Basal cell Carcinoma (Most Common),


Squamous cell Carcinoma (2nd Most
Common), and Melanoma (Most
Dangerous

First degree burn

Epidermal damage; red, swollen,


(edema) and pain

Second degree burn

Epidermal and upper dermal damage;


blisters appear

Third degree burn

Entire skin; skin is gray-white, cherry


red, or blackened, not painful (nerve
endings destroyed) or swollen and skin
grafting usually need

How can you estimate loss of fluids due


to burns?

Using the "Rule of Nine"

Histology

The study of tissues

Tissues

Groups of cells of common origin and


function

Epithelial tissue

Cover body surfaces or line a body cavity

Connective tissue

Connect, bind and support

Nervous tissue

Initiate and transmit impulses

Muscular tissue

Contractile tissues

What 3 things compose tissue?

Cells, fibers and ground substance

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Fibers and ground substance are


collectively called what?

Matrix

What three things you do to get a tissue


ready for microscopy?

Fixation, Sectioning, Staining

The layering of epithelial tissue can be


____or ____

Simple, Stratified

The cell shape of epithelial tissue can be


____, ____ or ____.

Squamous, cuboidal or columnar

What is the basement membrane made


of?

Glycoprotein plus collagenous and


reticular fibers

Simple squamous epithelium can be


found ____

In the inner lining of blood vessels,


external lining of organs such as the
lungs

Simple cuboidal epithelium can be


found ____

In the kidney tubules

Simple columnar epithelium can be


found ____

In the epithelium of the small intestines

pseudostratified columnar epithelium


can be found ___

In the trachea and bronchus

Stratified squamous epithelium that is


keratinized can be found ____

In the skin

Stratified squamous epithelium that isn't


keratinized can be found ____

In the esophagus and vagina

Transitional Epithelium can be found


____

Lining of the bladder

What are the 3 types of fibers found in


connective tissue

Elastic, collagenous and reticular fibers

What are the loose fibrous connective


tissues?

Areolar tissue, reticular tissue and


adipose tissue

What are the dense connective tissues?

Dense regular connective tissue, Elastic


connective tissue and dense irregular
conective tissue

Areolar tissue is found ___

In the hypodermis and messentery

Reticular tissue is found ____

In the spleen and lymph nodes

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Adipose tissue is found ___

In the breasts and surrounding organs

Dense regular tissue (white fibers) is


found ___

In tendons and ligaments

Dense regular tissue (yellow fibers) is


found ___

In the vocal cords

Dense irregular tissue is found ___

In the skin (dermis- reticular layer)


perichondrium, periosteum, etc.

Elastic connective tissue can be found


___

The walls of large arteries

What are the Supportive connective


tissues?

Hyaline cartilage and compact bone

Hyaline cartilage is found ___

In the costal cartilage and trachea

Elastic Cartilage can be found ___

On the flexible skeleton of the ear

Fibrocartilage can be found ____

In the intervertebral discs, meniscus

Compact bone is found ___

In the skeleton

What is the fluid connective tissue?

Blood

Blood is found ___

matrix: liquid plasma


cells: formed elements

What special structures are found in


areolar tissue?

Fibroblast, collagenous and elastic fibers

What special structures are found in


adipose tissue?

Adipose cells, fat storage

What special structures are found in


dense regular connective tissue (white
fibers)?

Collagenous fibers and fibroblast


(nucleus)

What special structures are found in


cartilage?

Chondrocyte and Lacuna

What special structures are found in


bone?

Osteocyte, central canal, lamella and


canaliculi

Gland

Cell or organ that secretes or excretes


substances

Endocrine gland

Gland that has no duct and secretes


hormones directly into blood

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Exocrine gland

Gland that secretes by way of duct to


body surface or organ cavity

Serous gland

Exocrine gland that secretes thin, watery


secretion

Mucous gland

Exocrine gland that secretes thick,


mucus secretion

Mixed gland

Exocrine gland that contains serous and


mucous cells

Where can the endocrine glands be


found?

Thyroid gland and islet cells of pancreas

Where can the exocrine glands be


found?

Sweat gland, mammary glands and acini


of pancreas

Where can the serous glands be found?

Sweat glands and pancreas

Where can the mucous glands be found?

Tongue, roof of mouth and respiratory


passages

Where can the mixed glands be found?

Salivary glands

Merocrine glands

Exocrine glands that secrete by


exocytosis

Holocrine glands

Exocrine glands that accumulate


products and then rupture.

Apocrine glands

Exocrine glands that accumulate


products, but only apex ruptures

What is an example and the functions of


the cutaneous membrane?

Skin; protection

What is an example and the functions of


the mucous membrane?

Digestive tract and respiratory passages;


to make protect from chemical and
physical abrasion and make things easier
to move

What is an example and the functions of


the serous membrane?

Stomach, peritoneum and pleurae; make


them moist/ secretes serous fluid

What two things are unicellular glands


that secrete mucus

Mucous Cells and Goblet cells

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What are the 3 Stages of tissue repair?

1. Inflammation
2. Organization
3.Regeneration and Fibrosis (Scarring)

axial skeleton (80) & appendicular


skeleton (126)

two divisions of the skeleton

skull bones, auditory ossicles, hyoid


bone, ribs, sternum, and bones of the
vetebral column

the axial skeleton consists of:

upper & lower limbs, and the bones


forming the girdles

the appendicular skeleton consists of:

frontal, parietal (2), occipital, sphenoid,


ethmoid, temporal (2)

name the 8 cranial bones

2 nasal bones, 2 maxillae, 2 zygomatic,


the mandible, 2 lacrimal, 2 palatine, 2
inferior nasal conchae, vomer

name the 14 facial bones

supraorbital margin

superior to the orbits, the frontal bone


thickens and forms:

supraorbital foramen

within the supraorbital margin, slightly


medial to its midpoint is a hole called:

supraorbital notch

if the supraorbital foramen is


incomplete, we refer to this as:

zygomatic process of temporal bone

projects from the temporal bone;


articulates with the temporal process of
the zygomatic bone

zygomatic process of temporal bone &


temporal process of zygomatic bone

two processes that form the zygomatic


arch

temperomandibular joint (TMJ)

the mandibular fossa of the temporal


bone and the articular tubercle
articulate with the mandible to form:

mastoid process

point of attachment for several neck


muscles

styloid process

serves as a point of attachment for


muscles and ligaments of the tongue &
neck

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coratid foramen

a foramen contained in the temporal


bone that the carotid artery passes

jugular foramen

a foramen contained in the temporal


bone that is a passageway for the juglar
vein and cranial nerves

foramen magnum

the inferior part of the bone that is the


opening through which the spinal cord
connects to the lower brain

medulla oblongata

inferior part of the brain that connects


with the spinal cord within the forman
magnum

occipital condyles

oval processes with convex surfaces on


either side of the foramen magnum;
articulate with the depressions on C1 to
form atlanto-occipital joint

alanto-occipital joint

allows your head to nod

hypoglossal foramen

allows the passage pf the hypoglossal


nerve, which innervates the tongue from
beneath; superior to each occipital
condyle

external occipital protuberance

a relatively prominent midline


projection on the posterior surface of
the occiptal bone

superior and inferior nuchal lines

two curved ridges that extend laterally


from the protuberance; allows the
attachment point for muscles

sella turcica

part of the sphenoid bone that is the


cube-like medial portion whose superior
surface is called the;

sella turcica

bony projection that surrounds and


protects the pituitary gland

greater wings

part of the sphenoid bone that projects


laterally from the body of the sphenoid;
and form the antero-lateral body of the
cranium

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lesser wings

part of the sphenoid bone; smaller and


form a ridge of bone anterior

ethmoid bone

major supporting structure of the nasal


cavity

superior & middle nasal conchae

scroll shaped projections on the lateral


walls of the nasal cavity; they increase
vascular & mucus membrane surface
area in the nasal cavities, which aids in
the snese of smell, and warm, moisten
and filter incoming air

nasal bones

paired bones which meet at the midline


of the nose and form the bridge of the
nose

maxillae

unite to form the upper jawbone; they


articulate with every bone of the face
except the mandible

palantine process

a horizonontal projection of the maxilla


that forms the anterior 3/4 of the hard
palate

zygomatic bones

bone that forms the prominences of the


cheek and part of the lateral wall and
floor of each orbit

lacrimal bones

bones that are line and small and form


part of the medial wall of each orbit

lacrimal sac

gathers tears and passes them to the


nasal cavity

lacrimal fossa

a groove that houses the lacrimal sac

vomer

a rougly triangular bone on the floor of


the nasal cavity; it forms the inferior
portion of the nasal septum

sutures

immovable joints found only between


skull bones

fontanels

mesenchyme filled spaces ina pre-born


pr new born infant skull commonly
called "soft spots"

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hyoid bone

a single "u-shaped" bone which is


suspended from the styloid process of
the temporal bone by ligaments and
muscles; it supports the tongue, and
commonly fractured during
strangulation; located in anterior of neck
between the mandible and larynx

33

# of vertebrae during early development

26

# of vertebrae in adults

7 cervical, 12 thoracic, 5 lumbar, 1 fused


sacral, & 1 fused coccyx

describe the vertebral column

thoracic & sacral

name the 2 convex curves of the


vertebral

cervical and lumbar

name the 2 concave curves of the


vertebral

body of vertebrae

the thick, disc-shaped anterior portion


which is the weight bearing portion

vertebral arch

include the pedicle and laminae; goes


together with the body to surround the
spinal cord

tranverse process

in the thoracic region, the articulation


site for the ribs

spinous process

in the lumbar region, is for muscle


attachment

superior and inferior articular processes

are for connecting the vertebrae


together

thorax

refers to entire chest

thoracic cage

skeletal part of the thorax

sternum, costal cartilages, ribs, and the


bodies of thoracic vertebrae

parts of the thoracic cage

sternum (or breastbone)

flat, narrow bone located in the center of


the anterior thoracic wall; it is composed
of 3 parts: manubrium, body, xiphoid
process

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ribs

12 pairs; gives structural support to the


sides of the thoracic cavity; they increase
in length from 1-7 and then decrease in
length from 7-12

true ribs

the first 7 pair of the ribs; each have a


piece of costal cartilage attaching them
to the sternum

false ribs

the last 5 pairs of ribs

floating ribs

rib 11 & 12 are flase ribs but also have


another name because they do not
attach to the sternum at all

hyaline cartilage

type of cartilage that makes up costal


cartilage

atlas

term for C1 cervical vertebrae

axis

term for C2 cervicle vertebrae

clavicle & scapula

each human has 2 pectoral girdles


consisting of which 2 bones:

clavicle

anterior bone that articulates with the


manubrium

scapula

articulates with the clavicle and with the


humerus; DOES NOT articulate with the
vertebral column

sternal end

rounded medial end of clavicle

acromial end

broad, flat lateral end of clavicle

scapula

large, triangular, flat bone situated in the


superios part of the posterior thorax at
the level of the 2nd and 7th rib

spine

prominent ridge on the posterior side of


the scapula

acromion

the lateral end of the spine; a flattened


process

glenoid cavity

inferior to the acromion; accepts the


head of the humerus

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body

the flattened triangular part of the


scapula bone

medial border

edge of scapula that is closer to the


vertebral column

scapular notch

a prominent indentation along the


superior border of the scapula

30

# of bones in the upper limb

humerus, radius, ulna, 8 carpals, 5


metacarpals, & 14 phalanges

the 30 bones in the upper limb are:

humerus

the longest and largest bone in the upper


limb; articulates proximally with the
scapula and distally at the elbow with 2
bones: ulna & radius

head

the proximal end of the humerus that is


rounded and articulates with the glenoid
cavity

anatomical neck

distal to the head of the humerus;


visable as an oblique groove

greater tubercle

lateral projection distal the anatomical


neck of the humerus

lesser tubercle

projects anteriorly from humerus; distal


to anatomical neck

surgical neck

the place where the bone consticts to


form the shaft; distal to tubercles

capitulum

a rounded knob on the lateral aspect of


the bone that articulates with the head
of the radius

trochlea

located medially to the capitulum and


articulates with the ulna

coronoid fossa

an anterior depression (receives the


head of the radius when forearm is
flexed) ; located on humerus

olecranon fossa

a posterior depression of humerus


(receives the olecranon of the ulna when
the forearm is extended)

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Anatomy and Physiology Test 2 (Ch. 4-7) flashcards | Quizlet

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medial and lateral epicondyles

rough projections on either side of the


distal end of the humerus where
tendons of muscles of the forearm attach

ulna

located on the medical aspect of the


forearm (pinky side) and is longer than
the radius

olecranon

at the proximal end of the ulna; forms


the prominence of the elbow

coronoid process

an anterior projection of the ulna that


receives the trochlea of the humerus

trochlear notch

a large curved area between the


olecranon and the coronoid process that
forms part of the elbow

radial notch

on the lateral side of the coronoid


process of the ulna; receives the head of
the radius

ulnar tuberosity

inferior to the coronoid process of the


ulna to which the biceps brachii muscles
attach

styloid process

located on the posterior side of the distal


end of the ulna (attachment of
ligaments)

radius

located on the lateral aspect of the


forearm (thumb side)

head of radius

the proximal end of the radius that


articulates with the capitulum of the
humerus and the radial notch of the
ulna

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