Professional Documents
Culture Documents
Many people are opposed to embryonic stem cell research; arguing that
human embryos should not be used for experimentation as each is potentially
a human life.
e.g.
for
transplanting into damaged
tissues (Stem cell therapy).
Remember asexual
reproduction?
Asexual reproduction is a
form of cloning.
Remember that some
organisms can reproduce
(by mitosis) e.g.
remember strawberry
plants - which form
runners, that become new
plants.
This was an example of
asexual reproduction
since the new plants have
exactly the same genes as
the parent plant (there is no
genetic variation) the
plants are clones!
But what about cloning
animals?
Well that were we
intervene
This form of
reproduction is
called: Asexual
reproduction.
All offspring
have exactly the
same genes as
the parent.
and Strawberries
1) They removed differentiated mammary cells from the udder of a six-year-old sheep. The cells were grown in
tissue culture, and then the concentration of nutrients was reduced for 5 days, causing them to pause at the
beginning of the cell cycle
2) Simultaneously, eggs obtained
from a ewe were enucleated.
3) Mammary cells and egg cells were surgically
combined in a process called somatic cell
nuclear transfer (SCNT).
Mammary cells and eggs were fused to
introduce the mammary nucleus into egg.
4) 29 developed into embryos,
which were then placed into the
reproductive tracts of surrogate mothers.
5) 5 months later, on July 5, 1996, one sheep
gave birth to a lamb named Dolly, the first clone
generated from a fully differentiated animal cell.
Therapeutic Cloning
First, skin cells are
isolated; then, using the
same procedure that
created Dolly, an
embryo is assembled.
After removing the
nucleus from the skin
cell, they insert it into an
egg whose nucleus has
already been removed.
Cloning mammals could help provide organs for organ transplants (which
would help solve the organ shortage problem).
Remember, if a
population is closely
related (few genetically
different alleles) and a
new disease appeared, it
could potentially wipe
out the population. This
is because there may not
be a disease resistant
allele in the population.
For example, the cloning procedure often fails to produce a viable clone. Dolly
the sheep is the most famous example of a cloned mammal and she only lived
to be 6 years old (which is about half the age many healthy sheep live to).
Dolly had to put down because she had many age related problems e.g.
arthritis and lung disease