Professional Documents
Culture Documents
Clinical Study
75 40 35
4
(P<0.05)
1 Clinical Data
1.1 Diagnostic criteria
Diabetes is diagnosed in reference to the diabetic
diagnostic criteria issued by the American Diabetes
Association in 1997.
The diagnostic criteria of peripheral neuropathy
cover the following aspects.
Sensory neuropathies are manifested by pain
(the pain can be burning, stabbing, dull or bursting,
etc.), hypersensitivity to temperature, numbness,
and stocking-glove distribution.
Motor neuropathies are manifested by
instability of gait, loss of ability to walk on heels, or
limited motion.
Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag Berlin Heidelberg 2010 249
2 Methods
Prior to treatment, all patients had received a
diabetic diet, studied the knowledge about diabetes
mellitus, and they were undergoing kinetotherapy.
And they had also learnt to self-detect the severity
of diabetes and to take hypoglycemic agents
3 Results
3.1 Evaluation indexes
3.1.1 Evaluation of symptoms and signs
The symptoms and signs were examined by the
same doctor, in accordance with the Guiding
Principles for Clinical Study of New Chinese
Medicines.
Marked effectiveness: The patient tells that the
symptoms and signs are diminished.
Effectiveness: The patient tells that the symptoms
and signs are reduced.
Failure: The patient complains of no
improvement in symptoms or signs.
250 Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag Berlin Heidelberg 2010
Pre-treatment
Post-treatment
Treatment
40
2.260.49
1.120.591)2)
Control
35
2.190.51
1.640.45
Table 2. The comparison of nerve conduction velocity between pre-treatment and post-treatment ( x s, m/s)
Groups
Treatment
40
Control
35
Time
MCV
Median nerve
SCV
Peroneal nerve
Median nerve
Peroneal nerve
Pre-treatment
41.111.46
39.914.23
36.453.61
33.493.64
Post-treatment
47.656.131)
46.705.931)
41.826.511)
40.696.421)
Pre-treatment
39.092.74
38.703.98
36.123.42
33.992.91
Post-treatment
40.344.59
39.793.66
38.433.941)
37.284.011)
4 Discussion
Diabetes mellitus is a commonly encountered
metabolic and endocrine disease. It falls under the
category of "Xiao Ke (wasting & thirsting
disorder)" in traditional Chinese medicine. DPN is
one of the chronic complications and causes for
disability, usually preceding the occurrence of
Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag Berlin Heidelberg 2010 251
References
[1] Dyck PJ. Detection, Characterization, and Staging of
Polyneuropathy: Assessed in Diabetics. Muscle Nerve,
1998, 11(1): 21-32.
[2] CHANG Hong. The Detective Analysis on the
Comprehensive Electrophysiology of EMG, SCV, MCV
and SEP in Diabetic Peripheral Neuropathologies. Acta
Academiae Medicinae Xuzhou, 2000, 20(5): 427-428
[3] ZHENG Hui-tian, LI Yong-fang, CHEN Guo-mei, et al.
Influence of the Kidney-tonifying and Meridian-dredging
Method in Acupuncture on Nerve Conduction Velocity of
Diabetic Peripheral Neuropathy. Acta Universitatis
Traditionis Medicalis Sinensis Pharmacologiaeque
Shanghai, 2000, 14(2): 58-60
[4] SUN Yuan-zheng, XU Ying-ying. Clinical Observations
on Treatment of 26 Diabetic Peripheral Neuropathy
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[5] ZHANG Xiu-hong. Clinical Study on Diabetic Peripheral
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Therapy. Chinese Journal of Urban and Rural Industrial
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[6] YAN Ji-hong. Treatment of 46 Cases with Diabetic
Peripheral Neuropathy by Acupuncture plus Methycobal.
Shanghai J Acu-mox, 2007, 26(9): 14-15.
Translator: HONG Jue ()
Received Date: April 20, 2010
252 Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag Berlin Heidelberg 2010