PHARMACOLOGY CONTROL TEST-1

Batch 305-SAITM
(Antimicrobials, Fe.Metabolism, Vitamins, Ca and
phosphate Metabolism)

1) T/F regarding antibiotics?

(a)Bactericidal drugs are more effective against rapidly dividing
organisms.T
(b)Minimum inhibitory concentration (MIC) is an indicator of potency of an
antibiotic. T
(c)Inappropriate use of broad spectrum antibiotics provides antibiotic
resisteance. T
(d)Initiation of empirical therapy is microbiologically guided.F
(e)Chemoprophylaxis indicated for large bowel surgery.T
2) T/F regarding antimycobacterial drugs;
(a)Dapsone is known to cause red usrine. F
(b)streptomycin can be safely given in pregnancy. F
(c) Ethambutol is known to cause optic neuritis.T
(d)Miliary TB is treated with the standard drug regime given for 8months.
T
(e)Pyrazinamide is the least likely out of the standard anti-TB drugs to
cause hepatotoxixity.F
3) T/F regarding antibiotics;
(a)Benzyl penicillin is given once in 21-28 days for rheumatic fever. T
(b)Gentamycin is well absorbed following oral administration. F
(c)Erythromycin is C/I in patients with penicillin allergy. F
(d) Chloramphenicol is known to cause grey baby syndrome. T
(e)Metronidazole is used to treat pseudomembranous colitis. T
4) T/F regarding B-lactam antibiotics;
(a)Cephalosporins inhibits the formation of peptidoglycan cross links in
bacterial cell wall.T
(b)Benzyl penicillin is acid stable.F
(c) Reduced dose of Benzyl penicillin are required by patients with renal
impairement.T
(d)Have a low therapeutic index.F
(e)Amoxicillin is B-lactamase resistant.F

5) Chloroquine;
(a)is a blood schizonticidal drug.T
(b)produces radical cure of plasmodium vivax infection.F
(c)has a large volume of distribution.T
(d)is C/I in pregnancy.F
(e)Hypotension is a risk seen during IV administration.T
6) T/F regarding anti-viral and anti-fungal drugs?
(a)Acyclovir is given IV in herpes simplex encephalitis.T
(b)acyclovir reduces the severity of herpes zoster infection is started
early.T
(c)Oseltamivir(Tamiflu) is recommended for post exposure prophylaxis of
healthy individuals.F
(d)Oral Nystatin is effective in the treatment of superficial candidiasis.T
(e)Anta-acids reduces the absorption of Ketoconazole.T
7) T/F regarding Vitamins;
(a) Hyperkalaemia is known to occur during the treatment of
pernicious anaemia.
(b)Vitamin B12 absorption is dependant on lipid metabolism.
(c) Vit.A is used for the treatment of psoriasis.
(d)Folic acid supplements are given via the oral route.
(e) Anta-acid can cause Pyridoxine deficiency.
8) In drug treatment for osteoporosis;
(a)Hormone replacement therapy in post-menopausal women is known to
increase the risk of endometrial carcinoma.
(b) Raloxifene reduces the incidence of hip fractures.
(c)Alendronate is safely prescribed in renal failure.
(d)Etidronate causes gastric irritation.
(e)Alendronate suppresses the bone resorption by osteoclasts.
9) T/F regarding Fe. Therapy;
(a)taking Fe with tea enhances absorption.
(b)Total Iron binding capacity is decreased in Fe. Deficiency anaemia.
(c)Serum Transferrin level is a measurement of Fe.stores.
(d)Ferrous gluconate has a higher efficacy than Ferrous sulfate.
(e)Discolouration of stools known to occur with Fe replacement therapy.

10) Best of 5:- For which of the following conditions is Tetracycline the drug
of first choice?
(a)Amoebiasis.
(b)Treatment of Chronic hyponatraemia due to syndrome of inappropriate
anti-diuretic hormone (SIADH) secretion.
(c)Prophylaxis of Malaria.
(d)Mycoplasma pneumonia of adults.
(e)Soft Tissue infections in patients who are allergic to B-lactams.