FACULTY RECRUITMENT TEST

CATEGORY-A

International Olympiads (Senior)

BIOLOGY
PAPER I
Time: 60 Minutes.

Maximum Marks: 40

Name: ........................................................................................................
Marks:
Subject: .....................................................................................................

Instructions:
Attempt all questions.
This question paper has Two Parts I and II. Each question of Part I carries 2 marks and of
Part II carries 4 marks.
PART I
1.

What is the role of lysosomes in lung fibrosis, rheumatoid arthritis and gout?

2.

How does mitosis in a cancer cell differ from in a normal somatic cell?

3.

(a) What is the molecule shown below?

D
C

b) What kind of bonds is indicated by the gray lines?

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FRT (APT / SAT / IO)2011-2012-[PAPER I]Biology2

4.

Facial Herpes is a human disease caused by a virus with genes of double-stranded DNA molecules.
What is a likely explanation for the periodic eruptions of symptoms in a person infected with the
herpes virus?

5.

Define photorespiration. Name the cell organelles involved in photorespiration.

6.

A woman with blood type O has a child with blood type O. She claims that a friend of hers is the
A
B
child's father. In the ABO system, I and I are both dominant to i and are codominant to each other.
ABO genotypes are summarized below

a) Her friends blood type is A. Can he be excluded as the father on this evidence alone?
b) Does the fact that the accused man's mother has type A and his father has type AB exclude him
from being the parent?

7.

How will you interpret the ECG (electrocardiogram) in which the time taken in QRS complex is higher?

8.

Fill the correct answer.

i) Homo sapiens emerged ____________years ago.
(p) 5,000
(q) 50,000
(r) 500,000
(s) 5,000,000

(t) 50,000,000

ii) There are __________________billion letters (bases) in the human genome.

(p) one
(q) three
(r) thirty
(s) 3 hundred
9.

Briefly mention the mechanism of action of FSH in males?

10.

Monoclonal antibodies have been called Magic Bullets by medical researchers. Write some of the
biological uses of monoclonal antibodies.

PART II
11.

You have identified a new, rapidly reproducing species of dog that you have named the
mitbull. The mitbull is diploid and two autosomal chromosomes are shown. One
chromosome carries gene A with two alleles designated A and a. The other chromosome
carries gene B with two alleles designated B and b.
Diagram mitosis in a heterozygous (AaBb) mitbull cell shown below. Draw your diagrams in
the outlines of the ovals adjacent to the stages. Include the alleles and the mitotic spindle in
your diagrams.

Mitbull cell

Metaphase

Prophase

Anaphase

Telophase

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FRT (APT / SAT / IO)2011-2012-[PAPER I]Biology3

12.

How do we code, codon, and anticodon differ?

13.

Mark the correct answers.

(a) With respect to the outside, the inside of a neuron at rest is:
(i) More negatively charged
(ii) More positively charged
(iii) The same charge
(b) Na+ and Cl- are:
(i) More concentrated inside the neuron
(ii) More concentrated outside the neuron
(iii) Are found in equal concentrations inside and outside the neuron
(c) K+ is:
(i) More concentrated inside the neuron
(ii) More concentrated outside the neuron
(iii) Is found in equal concentrations inside and outside the neuron
(d) The resting membrane potential of a neuron is determined by:
(i) Ions which can travel freely through channels in the resting neuron
(ii) Ions which cannot cross the resting neuron membrane
(iii) All ions (okay)
(iv) Ions do not determine the resting membrane potential

14.

You are reading a book out loud. Trace the path through the brain that the information takes from the
printed to the spoken words.

15.

Order the steps below in the life cycle of AIDS

a) Viral RNA degrades
b) cDNA integrated into host genome
c) New virus buds from cell
d) Viral proviral DNA becomes double stranded
e) Viral RNA translated into protein
f) Viral envelope fuses with host cell plasma membrane
g) viral RNA produced from host genome
h) Reverse transcriptase makes cDNA
i) cDNA enters the nucleus
j) New viruses are assembled
k) HIV binds to CD4 proteins

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