Human derived umbilical cord blood stem cell therapy:

New therapeutic weapon for cardiomyopathy

What is Cardiomyopathy?
Cardiomyopathy is disease of the heart muscle in which the heart muscle becomes infected,
enlarged, thick, or rigid.

Current Treatment
Treatment options can only manage cardiomyopathy or reduce risks and they depend on the type of
cardiomyopathy the patient has, the severity of the symptoms and complications, age and overall
health. Current treatment options cannot completely cure the disease. Treatments may include:

Heart-healthy lifestyle changes

Medicines
Surgery and implanted devices

The main goals of current treatments cardiomyopathy include:

Controlling signs and managing symptoms so that patient can live as normally as possible
Managing any conditions that cause or contribute to the disease
Reducing complications and the risk of sudden cardiac arrest
Stopping the disease from getting worse
Cardiomyopathy incidences in India
Cardiovascular diseases (CVDs) have emerged as the leading cause of mortality worldwide. In India,
1.7-2.0 million deaths are attributed to CVDs annually. The South Indian region, which is home to
one-fifth of the total population of India, accounts for ~25% of total CVD-related deaths in the
country. It is estimated that by 2030, death linked to cardiovascular complications will rise to 17.9
million in India alone, which is approximately 10 times the CVD-related mortality in the US.

Prevalence of cardiomyopathy is reported to be higher in the South Asian population as compared to

Western population. In India cardiomyopathy accounts for about 15-20% of sudden cardiac deaths.
Umbilical cord blood stem cell therapy to treat Cardiomyopathy
With a focus on recent advances that highlight the vascular potential exhibited by umbilical cord
blood stem cells, new found study proves the efficacy of umbilical cord stem cells in the cure of
cardiomyopathy. Umbilical cord blood stem cells have a significant potential to regenerate into
cardiac muscle cells. Potential mechanisms of umbilical cord blood stem cells and amelioration of
IDCM myocardium, consideration of these issues show that umbilical cord blood stem cells are
conceivably new therapeutic agents for this complex and elusive human disorder. Indeed umbilical
cord blood banking can create a healthier society.
Cord blood for transplants is collected from the umbilical cord after a newborn baby is delivered.
The stem cells from this cord blood are extracted in a Cell Processing Centre and preserved in -196
C liquid nitrogen tanks for future use.
Umbilical Cord Blood Banking Process

Considering the incidences of cardiac diseases, life threatening complications of cardiomyopathy and
high potential of umbilical cord blood stem cells; make the need for umbilical cord blood banking in
India evident.

Thank You
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