Eldrid Langester, 2009

Series of dissertations submitted to the
Faculty of Medicine, University of Oslo
No. 845
ISBN 978-82-8072-366-6
All rights reserved. No part of this publication may be
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Cover: Inger Sandved Anfinsen.

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Systemic Vascular Resistance (dynes.sec/cm5)

1500
B10/Phenyl
B10/Placebo
B7/Phenyl
B7/Placebo

1400
1300
1200
1100
1000
900
800
700

100

200
300
400
500
Time after spinal anesthesia (sec)

600

Figure 1. Mean differences in SVR between the four treatments groups. Baseline is marked on the y-

axis. SE (standard error) for each group is marked as error bars. (Paper I).
10
B10/Phenyl
B10/Placebo
B7/Phenyl
B7/Placebo

9.5

Cardiac Output (L/min)

9
8.5
8
7.5
7
6.5
6
5.5
5

100

200
300
400
500
Time after spinal anesthesia (sec)

600

Figure 2. Mean differences in CO between the four treatments groups. Baseline is marked on the yaxis. SE (standard error) for each group is marked as error bars. (Paper I).








 




 


  











 



 
 


 
 

 
 


  














 
 
 



 
  


9
Phenylephrine
Placebo

8.5

Cardiac Output (L/min)

7.5

6.5

5.5
0

100

200
300
400
500
Time after spinal anesthesia (sec)

600

  



100
Phenylephrine
Placebo
95

Heart Rate

90

85

80

75

70

100

200
300
400
500
Time after spinal anesthesia (sec)

600

 





 



 



   






 






  




   






   


  


   






 
 











 
 



































 















 
 
 
 
 
    


   
  





 
 

  
 
   


 
 






 





 




   

  


 











   





  












 













   






























  


 

  











Hemodynamic effects of oxytocin 5 units

CO (L/min)

12

8
6

SVR (dynes.sec.cm-5)

Healthy
Preeclampsia

10

20

40

60

80

100

120

140

160

20

40

60

80

100

120

140

160

20

40

60

80

100

120

140

160

20

40

60
80
100
Time (in seconds)

120

140

160

1400
1200
1000
800
600
400

SBP (mmHg)

160
140
120
100
80

110
SV (ml)

100
90
80
70