sVIII.

DRUG STUDY

Metronidazole

Drug Action Indication Adverse Reaction Nursing Patient Teaching

Consideration
Generic: Direct-acting -For Intestinal CNS: headache, -Do not give by IV -Instruct pt. to take
Metronidazole trichomonacide and amoebiasis, seizure, ataxia, bolus. extended-release
amebicide that Bacterial infections dizziness, syncope, tablets at least 1hr
Brand: works inside and caused by anaerobic in coordination, -Monitor liver before or 2hrs. After
Flagyl outside the intestine. microorganisms, confusion, function test results meals but to take all
It’s thought to enter Clostridium irritability, carefully in elderly other oral form with
Dose: the cells difficcile-associated depression, pt. food to minimize
500mg microorganisms that with diarrhea and weakness, insomnia G.I upset.
contain colitis. C.V: flattened T- -Observe pt. for
Route: nitroreductase, wave, edema, edema, especially if -Report lack of
Per Orem forming unstable -To reduce flushing, he’s receiving response , any
compounds that postoperative thrombophlebitis, corticosteroid; symptoms of CNS
Frequency: bind to DNA and anaerobic infection after I.V infusion Flagyl IV RTU may toxicity such as
TID for 10 days inhibit synthesis, following surgery. EENT: rhinitis, cause sodium numbness, seizures
causing cell death. sinusitis, retention and unusual
pharyngitis bleeding
G.I: nausea, -record number of
abdominal cramping stools and character -Do not perform
or pain, stomatitis, when drug is used tasks that require
epigastric distress to treat amoebiasis. mental alertness
-Drug may turn
urine brown; do not
be alarmed

Nexium
 Drug Action Indication Adverse Reaction Nursing Patient Teaching
Consideration
Generic: Suppresses the final -Reduce occurrence GI: diarrhea, -store between 15- -may take antacids
Esomeprazole step in gastric acid of gastric ulcers nausea, flatulence, 30°C with container -avoid alcohol and
Magnesium production by associated with abdominal pain, tightly closed OTC drugs products
inhibiting the continuous NSAID constipation, -reconstitute with unless approved
Brand: H+/K+ ATPase in therapy melena, vomiting 5ml of 0.9% NaCl -drug is for short
Nexium the gastric parietal CNS: headache, injection; withdraw term use only
cells. This decreases anorexia, confusion, 5ml of the -long term use may
Dose: gastric acid dizziness, migraine, reconstituted cause side effects
40mg secretion. sleep disorder, solution and give
insomnia over no less than 3
Route: CV: hypertension, minutes
Per Orem tachycardia -for use by IV
GU: dysmenorrhea, injection over 10-30
Frequency: mental disorder, minutes,
OD vaginitis, cystitis, reconstitute the
hematuria, polyuria contents of 1 vial
with 5ml of 0.9%
NaCl, lactated
ringer’s injection, or
D5W; further dilute
to a final volume of
50ml; give the final
diluted solution as
an IV infusion over
10-30 minutes

Celebrex
Drug Action Indication Adverse Reaction Nursing Patient Teaching
Consideration
Generic: Inhibits Anaphylactic >instruct client on how and when
Celecoxib prostaglandin > to decrease level reactions, renal > assess patient to take the pain medication
synthesis, producing of pain experienced toxicity, in history of
Brand: peripherally by the patient Hallucination, asthma, rhinitis, >Instruct patient to take
Celebrex mediated analgesia. ageusia, anosmia, uticaria and use medication exactly as directed. If
Also have anti- aseptic menlugitis, of aspirin dose is missed, it should Be taken
Dose: inflammatory vasculitis, GI as soon as remembered if not
200mg properties. hemorrhage, > assess almost time for the next dose. Do
Hepatitis, liver patients pain not double dose
Route: failure, interstitial
> obtain lab >may cause drowsiness or
Per Orem nephritis,
results of dizziness.
photosensitivity
urinalysis
Frequency: reaction, exfoliative >Advice patient to avoid driving
BID dermatitis, erythema to other activities requiring
multiforme, alertness until response to the
Stevens-Johnson medication is known.
syndrome, toxic
epidermal >instruct patient to avoid the
necrolysis & concurrent use of aspirin, alcohol,
menstrual disorder, NSAIDS, acetaminophen or other
Cerebral OTC medications without
hemorrhage, consulting medical practitioners.
fulminant hepatitis,
liver necrosis, >advise patient to inform health
hyponatremia, care provider of medication
conjunctivitis regimen prior to treatment and
surgery

Amlodipine

Drug Action Indication Adverse Reaction Nursing Patient Teaching

 Consideration
Generic: Inhibits influx of Headache, edema, >foods does not >take as directed,
Amlodipine calcium through the >Hypertension fatigue, affect once daily
cell membrane, >angina somnolence, nausea, bioavailability of >may take without
Brand: resulting in a >myocardial abdominal pain, Amlodipine meals; but foods
Norvasc depression of >ischemia flushing, >can be given help decrease
automaticity and >Reduce the risk of palpitations, safely with beta stomach upset
Dose: conduction velocity coronary dizziness. Asthenia, blockers, nitrates >report signs and
5mg in cardiac muscle. revascularization vasodilation & and nitrogycerin or symptoms of chest
Decreases SA and >fetal coronary epistaxis thiazides pain, shortness of
Route: AV conduction and heart disease >review list of breath, dizziness,
Per Orem prolongs AV node >non-fatal MI drugs prescribed to swelling of
effective and >stroke prevent interactions extremities
Frequency: functional refractory >use caution, may
OD periods. Slight experience light
decreases in HR. headedness or
dizziness
>may ask for
generic; cost
savings

Monowel

Drug Action Indication Adverse Reaction Nursing Patient

 Consideration Teaching
Generic: -Peritonitis & other G.I: nausea, vomiting -check if patient -instruct
intra-abdominal & intrapelvic has patient to report
infections, septicemia, Phlebitis and hypersensitivity any side effects
Brand: endocarditis, gynecological, inflammation at injection to cephalosporins experienced
respiratory tract, site
bone & joint, skin & -instruct patient
Dose: soft tissue infections, -chech with to report
UTI including uncomplicated doctor if patient swelling or pain
gonorrhea. has renal over the
Route: insufficiency, injection site
Intravenous pregnant and
lactating
Frequency:
Every 8 hours -To reduce postoperative -Observe pt. for
infection phlebities and
following surgery. inflammation on
site

-record number
of stools and
character when
drug is used to
treat amoebiasis.