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What is the expected bond to be formed between the two atoms atom 1(atomic
number 11) and atom 2(atomic number 17)?
a. Polar covalent positive in one end and negative in the other end (O-H,N-H)
b. Non polar covalent attraction is more equal (C-H)
c. Ionic transfer of electrons so two odd numbers are more likely
d. Hydrogen weak bond made by water molecules so obviously wrong
2. Which of the following non
4. True of polysaccharides
a. Gram negative cell wall is made up of thick layer of peptidoglycans - only
positive,gram neg is thin walled
sulphate has
no COOH
c. A link trisaccaride is found within the structure of glycoprotein only o and n linked
are found here, no A
d. Cellulose contains alpha(1->4) glycosidic linked glucose should be beta 1->4
linkages
5. All of the following statements is correct regarding proteins and amino acids
EXCEPT
a. Amino acids are classified based on the side chain or R group - CORRECT
b. The acid base property of amino acids depends on the ionization character of both
amino and carboxyl groups - CORRECT
c. The quarternary structure of a protein is possible only if the molecule consists of
more than one amount - CORRECT
d. Denaturation of proteins is associated with the disruption of peptide bonds is isnt
6. Which of the following amino acids is classified to be nutritionally
and has a polar
essential
7. The zwitter form of amino acidremember it is net sero charge if zwitter
a. Is the predominant ionic species at the isoelectric ph(ph1)
b. Moves towards the cathode during electrophoresis ask aly hehe
c. Has the maximum buffering function of amino acid only if pka=ph
8. In the delta
designated as carbon 1?
a. Terminal methyl carbon
b. n carbon
c. carbon of the carboxyl group yes, c of cooh is the cabon 1
d. omega carbon
9. in the formation of a ceramide, the fatty acyl group is attached to the alcohol
backbone at this site check handout, page 11(lipids)
a. alpha carbon or carbon 3
b. terminal carbon of the hydrocarbon chain
c. OH group at carbon 1
d. Amino group attached to carbon 2
10. True of the membrane protein figure shown (check
shifting exam 1)
11. This statement correctly describes the chemical nature of biologic
membranes
a. The component lipids and proteins are not essential components of the membranes
structure they are the main components
b. Membranes are solid structures at standard conditions they are fluid structures so
proteins and lipids can pass through
c. The two monolayers are asymmetric in nature- two faces of biologic membranes
always differ from one another
d. Most membranes have equal electrical charges inside and out inside more
negative
12. To cause an uncompetitive
all noncompetitive bind to allosteric sites(other areas not bound by the active site)
-
13. True of an enzyme EXCEPT
a. Ribonuclease molecule dna toh
b. Increase speed of product formation -CORRECT
c. Protein molecule conjugated proteins so correct
d. Catalysis affected by ph yupyup, others that affect are temp, enzyme
concentration, substrate concentration
14. The non protein organic portion of enzymes that acts as acceptor of functional
groups in a reaction is appropriately called
a. Holoenzyme complete active enzyme
15. Which of the following is the correct pair
16. In the calculation
component is the:
a. Energy used for muscular work
b. Obligatory thermogenesis extra energy expenditure for physical acivity
c. Resting metabolic rate energy required in awake state
d. Thermic effect of food increased heat production following intake of food
17. Among the major peptides
utilization, which is the only appetite stimulating?- last 2 pages of doc dakis handout
a. Ghrelin
b. Insulin
c. Leptin
d. PYY,aa
18. In the computati on of the desirable body weight in a Filipino adult. Using the modified
19. According to the chemiosmotic
Mitchell, the driving force behind the formation of ATP thru oxidative phosphorylation
is the
a. Formation of high energy intermediate within the mitochondrial matrix
b. Proton gradient created between the intermembranous space and the mitochondrial
matrix page 7 of bioenergetics
c. Coupling of the exergonic reaction with an endergonic reaction
d. Direct transfer of high energy phosphate to ADP
20. Which of the following components of complexes of the electron
transport
chain is associated with a P/O ratio of 3/1 when the reducing equivalents are
channelled into it? Page 6 of bioenergetics
a. NADH-CoQ oxidoreductase
b. FMN-CoQ dehydrogenase
c. Cytochrome b-c oxidoreductase
d. Cytochrome aa3 oxidase
21. In the phosphorylation of glucose to glucose 6 P catalyzed by hexokinase in the
presence of magnesium ions, an increase in the production of glucose 6 P slows down
the activity of hexokinase. This is an example of what
enzyme activity?
type of control
22.Hormone synthesis is after cleavage of signal sequence of the precursor
peptide:get from pheobe
a. Glucagon
b. Epinephrine
c. Dopamine
d. Vasopressin
23.Hormone which undergoes signal transduction after binding
to cell surface receptorfrom pheobe
a. Calcitonin
b. Calcitriol
c. Cortisol
d. Thyroxine
24. The form of estrogen
alpha reductase
a. Androsterone mineralocorticoid of the most potent form
b. Androstenediol
c. Androstenedione - major androgen from zona reticularis
d. Dihydrotestosterone - page 10 of steroid hormones
26. The second
27. Which enzyme
28. The most
carboxylase, utilizes the following to carry out its reaction -----------------says biotin
sa handout...check
a. Biotin, AMP, CH3
b. Biocytin, ATP, HCO3
c. ATP, biopterin, CO3
d. ADP, CH2, folate
30. These two opposing pathways , namely glycogenolysis
and
31.Key enzyme in protein digestion that activates the other digestive
enzymes of the pancreatic phase: page 3 of digestion of proteins
a. Chymotripsin
b. Elastase
c. Trypsin
d. Aminopeptidase
32. The most
33. The major
34. All of the following amino acids can serve as substrates
for
35.Action of pancreatic lipase on dietary lipids will produce which
of the following digestive products page 4 of lipid digestion
a. Cholesterol and 1 free fatty acid
b. Phophatidic acid and 1 free fatty acid
c. 1 free fatty acid and diacylglycerol
d. 2 free fatty acids and monoacyl glycerol
36. The end
via beta oxidation page 3 and 4 of fatty acid metab(confirm with aly)
a. Malonyl CoA
b. Propionyl CoA
c. Acetoacetyl CoA
d. Acetyl CoA
37. Which condition correctly
38. the synthesis
40. An isoform
a. COX 1
b. COX 2
c. LOX
d. Cytochrome p450
41. Complete hydrolysis of 1
yield the components: glycerol, fatty acid, phosphate and ethanolamine. In which of the
following molar reactions? See samplex of modifications of this question( 2nd shift quiz,
2nd shifting exam and other finals)
a. 1:1:2:1
b. 2:1:2:1
c. 1:1:1:1
d. 1:2:1:1
42. The nitric
b. Endothelial cells
c. RBCs
d. Post synaptic neuron
43. Which organ id dependent on fatty
metabolic integration
a. Brain
b. Heart
c. Kidney
d. Liver
44. With an abundant blood supply of metabolic fuels after
45. The TCA
blood
generalities page 4
a. Embden-meyerhof pathway ATP and NADH
b. Rappoport leubering shunt 2 3 DPG
c. Hexose monophosphate shunt
d. Methemoglobin reductase pathway NADH from EMP
47. Protein separation based on molecular
48. Which of the following is NOT
49. Which statement pertains to the biological
function of
immunoglobulin M(IgM)-page 7 of immunoglobulins
a. Binds and fixes complement
b. Chief immunoglobulin in mucosal surfaces and secretions
c. Mediates allergic reactions by activation of mast cells
50. Which region
51. Figure of immunoglobulin review figures in handout
a. IgE
b. IgM
c. IgA
d. IgD
52. One of the following is true
53. Which of the following steps is the final
incorporates ferrous iron into protoporphorin IIIto produce heme? Page 11 of iron and
heme metabolism
a. Ferrochalatase - occurs in mitochondria
b. ALA dehydrogenase
c. Uroporphyrinogen 1 synthase of HMB synthase
d. Protoporphyrinogen oxidase
54.Haemoglobin is a better O2 transporter than myoglobin
because:
a. Haemoglobin has a higher affinity for oxygen
b. Haemoglobin binds to oxygen in a cooperative manner
c. The concentration of haemoglobin is higher than myoglobin within erythrocyte
d. Haemoglobin exists in either the T state or the R state
55. Principal transport
56. True of the oxygen
58. True of oxygen
59. Which of the following reactive
60. The intermediate of glutamine
renal cells in generating the much needed energy in the form of ATP through Krebs
cycle page 5 of kassie wassie notes 2009
a. Alpha-ketoglutarate
b. Glutamate y-semialdehyde
c. Glutamate
d. Isocitrate
61. The source of energy
62.Guanine is linked to the ribose sugar at ____________position
page 7 of chemistry of nucleic acids. Remember A&G is N9, C&T is N1
a. N1
b. N9
c. N6
d. N12
63. True about physical
65. One of the following conditions will lead
page 41 or 42 of ppt
a. Low levels of PRPP synthetase dapat high levels
b. Low activity of PRPP amido-transferase dapat loss of feedback inhibition
c. High levels of HGPRTase should be low levels
d. Impaired uric acid excretion
66. Which of the following DOES
review video
a. Separation of dsDNA to ssDNA in prepriming stage
b. RNA Pol catalyzing the synthesis of the RNA primer in the lagging strand
c. Elongation of the chain catalyzed by DNA pol III
d. DNA pol 1 for nick translation
67.True of eukaryotic cells
a. Gene expression is controlled at the level of transcription and translation review
video
b. Transcription and translation occur simultaneously
c. There are 3 release factors for the termination of translation
68.Transition, as a mechanism of mutation, is exemplified by a base
change from: it is the replacement of a purine to purie or pyrimidine to pyrimidine(a&g
purine, c&t-pyrimidines)
a. Adenine->cytosine
b. Adenine->guanine
c. Cytosine->guanine
d. Thymine->adenine
69. The most common consequence of excessive
exposure of DNA to UV
70. Which one of these genes is classified as a tumor
71. Formation of the Philadelphia chromosome in chronic
myelogenous
a. Point mutation
b. Amplification
c. Gene translocation
d. Tumor gene suppression
72.PCR which temperature allows denaturing lab notes
a. 20-25 -none
b. 54-60 - annealing
c. 72-75 elongation
d. 90-95
73.Southern blot transfer is a specific hybridization method for:
a. DNA
b. DNA-protein southwestern
c. Protein western
d. RNA northern
74. DNA analysis can be used to initially determine at least how many male factors are
involved in a gang
75. For the locus TPOX, and individual is HETEROZYGOUS with allele tandem
repeats of 13, 15 and with frequencies of 1, 0.33 to compute the probability based on
HARDY Weinberg Equilibrium, the formula is:
a. PP homo dominant
b. qq homo recessive
c. 2Pq
d. QRS-none
76.Inborn errors of metabolism are a result from first page of IEM.
Correction in test
a. Deficiency of substrate - no
b. Accumulation of products no
c. Inhibition of secondary pathways yes
d. Accumulation of co factors - no
77.Treatment modalities for decreasing substrate
availability in IEM include: mentioned in lecture
a. Modification of diet
b. Co factor supplementation
c. Gene therapy
d. Increased disposal of toxic metabolites
78. Which of the following is responsible for the increased
amount of
c. Adrenotoxin
d. NADPH
79. The major
80. In the synthesis of collagen
the formation of disulfide bonds between cysteine residues in extension peptides occur
in the? Page 10, biochemistry of connective tissue
a. Mitochondria
b. Endoplasmic reticulum
c. Vacuoles
d. Golgi sac
81.William Beuren disease is associated with this: page 6 of biochem of
connective tissue
a. Keratin defects
b. Deletion of the elastin gene
c. Defective procollagen peptidase
d. Decrease levels of procollagen
82. The brain:-over emphasized
83. The most
lecture
a. Acetylcholine
b. Glutamate
c. Dopamine
d. Aspartate
84. Which accessory
Review of physio
a. Titin
b. Troponin C
c. Calsequestrin
d. Tropomyosin
85. Which of the following is true
87. In the olfactory
88. Which of the following is/are the taste receptors of the taste
bitter page 5 of
taste
a. T2R
b. T1R1 and T1R3
c. T1R2 and T1R3
d. PKD2L1
89. The type
90.Werners syndrome, a premature again syndrome is brought about by
mutation in:page 6 biochemistry of aging
a. SOD gene
b. Lamin gene
c. WRN gene
d. Bcl gene
91. The oxidative
contribute to the overall effects of aging, the following is an example of free oxygen
radical review of doc bautistas lecture
a. Superoxide dismutase
b. Hydrogen peroxide
c. Catalase
d. Peroxidise
92. Which nutritional advice is correct
overemphasized
a. A daily intake of 40 grams is recommended
b. A high fiber intake should be accompanied by sufficient fluid intake
c. Cellulose and hemicellulose are better preffered than pectins and mucilages
d. Soluble fiber should be emphasized over the insoluble form
93. To maintain optimum health in a Filipino adult, which proportions of carb-protien-
b. 60-15-25
c. 70-10-20
d. 80-10-10
94. Which of the following is NOT
95. Cardinal sign
96. Most common cause
a. Iron deficiency
b. Vitamin a deficiency
c. Iodine deficiency
d. Undernutrition
97. Which experiment separated substances based
on their relative
a. Lipid profile
b. Vitamin c saturation test
c. Amino acid titration
d. Paper chromatography
98. Which laboratory procedure tested the behaviour
of ampholitic
electrolytes (ampholytes), such as amino acids, in the
presence of varying concentrations of acid (HCI) and base (NaOH)? lab notes
a. Centrifugation
b. Immunoassay
c. Titration
d. Precipitation
99. This laboratory experiment involved the reproduction
of several copies
ELISA
b. SEC
c. PCR
d. PAGE
100.This dye is used