Professional Documents
Culture Documents
ORIGINAL RESEARCH
W E N G L . - C . , D A I Y . - T . , H U A N G H - L . & C H I A N G Y - J . ( 2 0 1 0 ) Self-efficacy, selfcare behaviours and quality of life of kidney transplant recipients. Journal of
Advanced Nursing 66(4), 828838.
doi: 10.1111/j.1365-2648.2009.05243.x
Abstract
Title. Self-efficacy, self-care behaviours and quality of life of kidney transplant
recipients.
Aim. This paper is a report of an exploration of the effects of self-efficacy and
different dimensions of self-management on quality of life among kidney transplant
recipients.
Background. Self-efficacy is an important factor influencing self-management.
Patients with higher self-efficacy have better self-management and experience better
quality of life. Self-efficacy influences the long-term medication-taking behaviour of
kidney transplant recipients.
Method. A longitudinal, correlational design was used. Data were collected during
20052006 with 150 adult kidney transplant recipients on self-efficacy, self-management and quality of life using a self-efficacy scale, self-management scale and the
Medical Outcomes Scale SF-36 (Chinese), respectively. Relationships among variables were analysed by path analysis.
Results. Participants with higher self-efficacy scored significantly higher on the
problem-solving (b = 051), patientprovider partnership (b = 044) and self-care
behaviour (b = 055) dimensions of self-management. Self-efficacy directly influenced self-care behaviour and indirectly affected the mental health component of
quality of life (total effect = 014). Problem-solving and partnership did not statistically significantly affect quality of life. Neither self-efficacy nor self-management
had any effect on the physical health component of quality of life.
Conclusion. Transplant care teams should incorporate strategies that enhance selfefficacy, as proposed by social cognitive theory, into their care programmes for
kidney transplant recipients. Interventions to maintain and improve patients
self-care behaviour should continue to be emphasized and facilitated. Support to
enhance patients problem-solving skills and the partnership of patients with health
professionals is needed.
Keywords: kidney transplant recipients, nursing, quality of life, self-care
behaviours, self-efficacy, Taiwan
828
Introduction
Kidney transplantation (KT) is indicated in end-stage renal
disease (ESRD). Almost 50,000 kidney transplantations are
performed annually in the world (WHO 2003). In 2005,
17,429 patients with ESRD underwent kidney transplantation in the United States of America (National Kidney and
Urologic Disease Information Clearinghouse 2005). A total
2536 patients received a kidney transplant (or combined
kidney and pancreas transplant) between April 2008 and
March 2009 in the United Kingdom (organdonation.nhs.uk
2009), while in Taiwan, from 1997 to 2006, 1837 patients
underwent the procedure (Bureau of National Health Insurance 2007). The survival rates of grafts and patients have
dramatically increased during the past decade (Pirsch 2003).
Thus, improving the quality of life (QOL) of patients with KT
has become an important issue for transplantation teams
(Habwe 2006). Quality of life is demonstrated through the
physical, psychological and social domains of health and
appears to be influenced by a persons experiences, beliefs,
expectations and perceptions (Burra et al. 2007).
The KT recipients continue to live with a chronic condition
because they run the risk of chronic rejection, infection or
graft function failure (Pirsch 2003). Thus, these patients need
to take responsibility for their own care after KT. Selfmanagement has been recognized on a worldwide basis as an
important aspect of successful health care (Bodenheimer
et al. 2002, Linnell 2005). Self-management involves several
dimensions: problem-solving, decision-making, resource utilization, patientclinician partnership, self-care behaviours
and active participation in care (Lorig & Holman 2003,
Curtin et al. 2005). Self-management has been shown to
improve health function, decrease readmission rates and
promote QOL (Lorig et al. 2001, Glasgow et al. 2007).
Self-efficacy is a psychological construct defining a persons
confidence in performing a particular behaviour and in
overcoming barriers to that behaviour (Bandura 1994).
Patients with greater self-efficacy have been shown to practise
more self-management behaviours, leading to better disease
control, better physical function and better QOL (Gaines
et al. 2002, Tsay & Halstead 2002). Among KT recipients,
only a few studies have explored the relationship between
self-efficacy and medication-taking behaviour, showing that
KT recipients with higher self-efficacy adhered better to
medication-taking behaviours (De Geest et al. 1995, Christensen et al. 2000, Baines et al. 2002).
According to social cognitive theory, greater self-efficacy
may improve outcomes through specific behaviours (Bandura
1994). To determine whether one variable (explanatory)
can influence another variable (outcome), the explanatory
2010 Blackwell Publishing Ltd
Background
Quality of life among patients with kidney transplant
Cross-sectional research suggests that overall QOL improves
after KT (Chen et al. 2007, Smith et al. 2008) and is better
than that of patients receiving other renal replacement
therapy (Niu & Li 2005, Liem et al. 2007). However, the
long-term QOL of KT recipients has been reported not to be
equal to that of healthy controls in the general population
(Karam et al. 2003, Neipp et al. 2006). The QOL of KT
recipients has been shown to be affected by symptom distress
(De Geest & Moons 2000, Matas et al. 2002, Chen et al.
2007), anxiety and depression (Perez-San-Gregorio et al.
2006), and rejection and infection (Rebollo et al. 2000, Griva
et al. 2002). Moreover, personal and psychosocial environmental factors that influence QOL need to be specified more
clearly in kidney transplantation (Dew 1998).
Design
A panel design was used to collect data from adult KT
recipients at two points in time: at the time of the first crosssectional data collection (beginning in September 2005) and
6 months after the first collection.
Participants
Patients who had received kidney transplants were recruited
from the outpatient clinic of a 3,000-bed tertiary private
hospital in northern Taiwan. To be included in the study,
they had to (i) have received a KT at least 6 months and no
longer than 10 years prior (we thought that acute phase and
long-term survivors might have different stressors and receive
different treatment protocols, which could affect the results);
(ii) be at least 18 years old; (iii) be in a stable medical
condition; and (iv) agree to participate. Taking into consideration access to participants and the need for certain
statistics, we used PASS (power analysis and sample size)
software to estimate the number of participants needed.
Setting the a level at 005 and the power at 080, we
determined that we needed to include 120 patients as well as
allowing for a 10% attrition rate. Thus, the sample size was
set at 132.
The data were collected over a 15-month period in 2005
2006. Of the 186 patients who met the inclusion criteria, 31
refused to participate. Thus, the sample for the first data
collection included 155 patients (155/186, 833%). For the
second data collection (6 months later), four patients did not
complete the questionnaire after two telephone reminders,
and another was lost to follow-up. Thus, the final sample
included 150 KT recipients (150/155, 968%). Examination
of age, sex, time after transplantation (years) and renal graft
function showed no statistically significant differences among
patients who refused to participate or who did not complete
the second questionnaire and the final sample.
The study
Data collection
Aim
The aim of the study was to explore the effects of self-efficacy
and different dimensions of self-management on quality of
life among KT recipients.
Three hypotheses were addressed: (i) self-efficacy is
positively and significantly related to each dimension of selfmanagement, (ii) self-efficacy is positively and significantly
830
chose the response for each item that best matched their
situation over the past 2 weeks. Total scores range from 0 to
63, with higher scores representing more depressive symptoms. To examine validity, we used exploratory factor
analysis and principal component analysis, followed by a
varimax rotation. A two-factor structure for the 21 items of
the Beck Depression Inventory was identified. The percentage
of variance explained was 403%. We used the sum of the
scores of the scales for analysis, and Cronbachs a for this
study was 089.
earlier (SD = 27) (Table 1). The number of men and women
was nearly equal. The majority had religious beliefs (667%),
were married (678%), and were employed (687%). The
largest proportion had completed high school (374%). The
majority (513%) of patients had over three mismatches in
HLA typing, and most (853%) received a cadaver kidney.
Among the 22 recipients from a live donor, most received the
new kidney from a sibling.
Among the mean scores for the eight SF-36 subscales, the
highest was for bodily pain, followed by physical function,
social function, role-emotional, mental health, role-physical
and vitality (Table 2). The lowest subscale score was for
general health. The mean MCS score was 459 (SD = 102)
and PCS was 509 (SD = 72). Average scores for the selfmanagement dimensions of problem-solving, patientprovider partnership and self-care behaviours were 304, 119
and 393 respectively. The average score for self-efficacy was
423, depressive symptoms was 83, symptom distress was
137, the physical stress index was 17 and the cGFR was 545
(Table 2).
Ethical considerations
The study was approved by the research ethics committee of
the study site.
Data analysis
Data were primarily analysed by path analysis. Hypothesized
relationships among variables were examined by multiple
linear regression analysis (Frankfort-Nachmias & Nachmias
2000, Chiu 2003). Variables were entered into each regression model by forced entry. The causeeffect relationship
between self-efficacy and self-management was analysed as
the time-interval effects between these variables. Thus, the
measurement of self-efficacy was based on the data collected
at the first point in time, while the measurement of selfmanagement and QOL was based on data collected at the
second point. Other data, which served as control variables,
were used for the first-time data in the regression model.
Before path analysis, the assumptions of normal distribution, homoscedasticity, multicollinearity for dependent (outcome) variables and the normality of residuals (Loether &
McTavish 1980) were examined and assured (Weng 2008).
Results
Participant characteristics
Participants had a mean age of 418 years old (SD = 104) and
had received their kidney transplant a mean of 46 years
832
Mean
Age (years)
418
Time since kidney
46
transplant (years)
Gender
Male
Female
Tissue typing
2 mismatches
3 mismatches
Immunosuppressant regimen
Neoral-based
FK 506-based
Other
Source of kidney transplant
Cadaveric
Living relative
SD
104
27
73
77
487
513
73
77
487
513
66
77
7
440
513
47
128
22
853
147
Mean
SD
825
622
849
593
602
782
707
674
509
459
175
392
187
204
183
189
370
180
72
102
305
119
393
423
83
137
17
545
64
32
72
69
76
98
10
204
Range
15100
0100
10100
0100
5100
0100
0100
8100
286663
141661
1240
016
1552
1752
041
145
06
891223
014 (055 self-efficacy 025 self-care behaviour). No statistically significant, indirect effect of self-efficacy on physical
health was found, however. Among the three dimensions of
self-management, only self-care behaviour had a direct,
positive and statistically significant effect (b = 025,
P < 005) on mental health (Table 3). The simple relationships among self-efficacy, self-management, and mental and
physical health are shown in Figure 1.
Discussion
Study limitations
This study had several limitations. First, the generalization of
results may have been compromised by recruiting patients
from only one study site, although having one site ensured
homogeneity of the study sample as treatment protocols may
differ among medical centres. Further research should
balance generalization and homogeneity by including patients
from different transplantation centres.
Another limitation was that patients were included only if
they had received KT at least 6 months earlier. Thus, our
results do not reflect the situation of patients during the first
6 months after transplantation. In addition, the interval
between first data collection and follow-up was only
6 months, which might have been too short of a time for
study variables to react.
PS
Self-efficacy
Self-management
Patientprovider partnership (PPP)
Self-care behaviour (SC)
Problem-solving (PS)
Physical stress
Symptom distress
Depressive symptoms
Age
Time since kidney transplant
Gender
Organ source (1 = cadaveric)
Tissue typing
cGFR
R2
Adj. R2
F
P
PPP
SC
PCS
MCS
051**
044**
055**
006
010
002
018
003
008
008
001
005
005
003
026
021
496
000**
012
010
003
015
002
002
006
-001
007
027
021
503
000**
003
005
011
021*
017*
004
003
004
001
044
040
170
000**
001
011
003
005
012
017
025*
017
022*
006
010
010
021
013
278
0002*
006
025*
002
003
022*
030**
007
006
003
001
005
009
036
029
578
000**
833
006
Problem-solving
051**
Self-efficacy
003
PCS
011
055**
Self-care
behaviour
001
044**
Patient-provider
partnership
025**
002
006
MCS
010
Time 1
Time 2
Quality of life
Our results show that kidney transplant recipients had an
overall average QOL. They did not suffer from functional
limitation or distress related to pain, reflecting our inclusion
criterion of a stable medical condition (good renal graft
function). Perception of general health was the poorest
among the eight SF-36 subscales, consistent with previous
studies (Griva et al. 2002, Houle et al. 2002, Ekberg et al.
2007). After receiving KT, patients experience fewer uncomfortable symptoms and less pain, as well as no longer needing
to be attached to a machine. However, the need for long-term
medication, frequency of medical follow-ups, laboratory
examinations, and threat of rejection or infection made some
participants feel that their health status was not good enough.
Time 2
Conclusion
Self-efficacy can improve self-management and will benefit
QOL indirectly for patients with KT. Their self-efficacy can be
promoted by four strategies: mastery, modelling, persuasion
and learning. Transplantation nurses can help patients experience mastery by guiding them to set goals and develop action
plans to restore physical activity, adhere to a medication
regimen, and re-engage in social interaction. The second
strategy, modelling, could be achieved by introducing a
835
patient with KT to someone who has had a successful selfmanagement experience. In the third strategy, persuasion,
nurses can encourage and support patients to adopt healthy
behaviours by explaining to them that they have the ability
take care of themselves. The last strategy, learning, involves
thoroughly explaining the bodys responses to patients.
Transplantation nurses could help patients to learn about
the effects of KT treatment and how the body responds. Thus,
they will learn to more efficiently manage their symptoms,
which will result in a sense of confidence and well-being.
Self-care behaviour was found to be positively and directly
associated with QOL. We should realize that the scope of
self-care behaviour goes beyond taking medication and
regularly visiting a clinic. Educating and coaching patients
after KT should include the full range of self-monitoring
strategies, prevention of side effects, help-seeking behaviours
and mental adjustment. Further, nurses should discuss with
patients any difficulties that they might have in applying selfcare behaviours in daily life, and suggest strategies to help
resolve these difficulties. The goal is to familiarize patients
with these behaviours, encourage them to participate in their
care, give them confidence, and help them to realize their
responsibility in post-KT care.
Funding
This study was supported in part by a grant from the National
Council of Science in Taiwan (NSC95-2314-B-182-051).
Conflict of interest
No conflict of interest has been declared by the authors.
Author contributions
WLC and DYT were responsible for the study conception
and design. WLC and HHL performed the data collection.
WLC performed the data analysis. WLC, DYT, HHL and
CYJ were responsible for the drafting of the manuscript.
WLC, DYT, HHL and CYJ made critical revisions to the
paper for important intellectual content. WLC, DYT and
HHL provided statistical expertise. WLC obtained funding.
DYT and CYJ provided administrative, technical or material
support. WLC and DYT supervised the study.
References
Baines L.S., Joseph J.T. & Jindal R.M. (2002) Compliance and late
acute rejection after kidney transplantation: a psychomedical
perspective. Clinical Transplantation 16, 6973.
836
837
Weng L.C., Dai Y.T., Wang Y.W., Huang H.L. & Chiang Y.J. (2008)
Effects of self-efficacy, self-care behaviour on depressive symptom
of Taiwanese kidney transplant recipients. Journal of Clinical
Nursing 17(13), 17861794.
World Health Organization (2003). Human Organ and Tissue
Transplantation. Retrieved from http://www.who.int/ethics/topics/
en/human_transplant_report.pdf on 10 October 2009.
The Journal of Advanced Nursing (JAN) is an international, peer-reviewed, scientific journal. JAN contributes to the
advancement of evidence-based nursing, midwifery and health care by disseminating high quality research and
scholarship of contemporary relevance and with potential to advance knowledge for practice, education, management
or policy. JAN publishes research reviews, original research reports and methodological and theoretical papers.
For further information, please visit the journal web-site: http://www.journalofadvancednursing.com
Reasons to publish your work in JAN
High-impact forum: the worlds most cited nursing journal within Thomson Reuters Journal Citation Report Social
Science (Nursing) with an Impact factor of 1654 (2008) ranked 5/58.
Positive publishing experience: rapid double-blind peer review with detailed feedback.
Most read journal globally: accessible in over 6,000 libraries worldwide with over 3 million articles downloaded online
per year.
Fast and easy online submission: online submission at http://mc.manuscriptcentral.com/jan with publication within 9
months from acceptance.
Early View: quick online publication for accepted, final and fully citable articles.
838