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Clinician

Information
Manual
The Great Plains Laboratory, Inc.
11813 W. 77th St.
Lenexa, Kansas 66214
CustomerService@GPL4U.com
www.GreatPlainsLaboratory.com
913-341-8949 Toll-Free 800-288-0383

Your Representative
___________________________________
Account Representative
___________________________________
Direct Line
___________________________________
Mobile
___________________________________
E-mail

Revised: 7/13/2015

Clinician Information Manual


Getting Started with Lab Testing

Introduction to The Great Plains Laboratory, Inc.


Test Kit Order Form
Additional Resources Available on Our Website
Brochures Available on Our Website
GPL3 and GPL4 Panels

Clinical Lab Test Recommendations

Top 5 Recommended Tests


Clinical Significance of the Organic Acids Test

Test & Pricing Information

Physician Test Price List


Patient Test Price List
Test Descriptions

Turn-Around Times and Specimen Collection

Insurance Billing, CPT & ICD-9 Codes

Insurance Overview
Insurance Coverage Verification Guide
CPT Codes for Insurance Billing (Individual Tests & Test Panels)
ICD-9 Codes for Insurance Billing

Sample Test Requisition Form

Nutritional Supplements

Distributor Price List


New Client Form

Introduction to Integrative Medicine for Mental Health (IMMH)

Introduction to IMMH & IMMH Website


Recommended Testing for Mental Health Patients
Introduction to Zeebra Formulations
Practitioner Supplement Recommendations

William Shaw, Ph.D., Director

11813 West 77th Street, Lenexa, KS 66214

(913) 341-8949

Fax (913) 341-6207

www.GPL4U.com

Getting Started With Lab Testing

Getting Started
With Lab Testing

Getting Started with Lab Testing

Introduction to The Great Plains Laboratory, Inc.


Welcome to The Great Plains Laboratory, Inc., where customer service is our number one
priority. Our friendly staff is dedicated to helping both medical practitioners and patients to
achieve their maximum potential through accurate and informative laboratory testing. As a
client, you will appreciate the personal, one-on-one service that sets our laboratory apart from
the rest. We hope you will take advantage of the new clinical tests we have to offer based on
the latest research.
Our laboratory staff works diligently with medical practitioners and individual patients to ensure
that test results are thoroughly understood. Our knowledgeable customer service
representatives are available by phone and by email to answer questions and to provide clear
advice about how to order our tests. Our clients receive the maximum value for their test
results, which includes a professional consultation.
At The Great Plains Laboratory, Inc., we have coupled advanced technology with friendly
assistance to offer the most complete, reliable, and understandable laboratory testing available.
We look forward to working with you soon.
Sincerely,

William Shaw, Ph.D.


Laboratory Director

Website: www.GPL4U.com
E-mail: CustomerService@GPL4U.com

Getting Started with Lab Testing

KitOrderForm

Faxto:9133245262

ClinicName:

PhysicianName:

PhysicianPhone:

PhysicianTitle:

PhysicianEmail:

PhysicianFax:

ClinicStreetAddress:
ClinicCity,State&Zipcode:
Quantity TestKits

Quantity TestKits

URINEKITS

BLOODKITS

AminoAcidsUrineTestRandomCollection

AminoAcidsPlasmaTest(USonly)

AminoAcidsUrineTest24HrCollection

AdvancedCholesterolTest
IgEFoodAllergyBasicTest
IgEInhalantAllergyBasicTest

Gluten/CaseinPeptidesTest
GPLTOXProfile
MetalsUrineTestRandomCollection
MicrobialOrganicAcidsTest(MOAT)
OrganicAcidsTest(OAT)
PhospholipaseA2ActivityTest
UricAcidTestRandomCollection

CReactiveProteinTest(hsCRP)
CeliacDiseaseTest
IgGFoodAllergyTestw/Candida
IgGAsianFoodAllergyTestw/Candida
IgEFoodAllergyEssential(12)Test
IgGFoodAllergyTest+IgEFoodAllergyEssential(12)Test
PrealbuminTest
StreptococcusAntibodiesProfile
VitaminDTestSerum

KryptopyrroleTest(USonly)

IgEAllergyAdvancedCombinedTest

MetalsUrineTest24HrorTimedCollection
UricAcidTest24HrCollection

IgEFoodAllergyAdvancedTest
IgEInhalantAllergyAdvancedTest
CeruloplasminTest
Copper/ZincProfile
ComprehensiveFattyAcidsTest(US&Canadaonly)

PorphyrinsTest

STOOLKITS
MetalsFecalTest

IgGFoodAllergyTestw/CandidaDriedBloodSpot(DBS)
IgGAsianFoodAllergyTestw/Candida(DBS)
ImmuneDeficiencyProfile

YeastCulturew/SensitivityTest

MetalsRedBloodCellTest

ComprehensiveStoolAnalysis

COMBOKITS
MOAT+YeastCulturew/SensitivityTestCombo
OAT+AminoAcidsUrineTestComboRandom___24hr___
OAT+IgGFoodAllergyTestw/CandidaDBSCombo
OAT+IgGFoodAllergyTestw/CandidaSerumCombo

MetalsWholeBloodTest
VitaminDTestDriedBloodSpot(DBS)

SALIVAKITS
HormonesComprehensivePanel
HormonesComprehensivePlusPanel
HormonesShortComprehensivePanel

OTHERMATERIALS

OAT+YeastCulturew/SensitivityTestCombo

GPLInformationGuides

GPL3:OAT+IgGFoodAllergyTestDBS+MetalsHair

PediatricCollectionBags

GPL4DBS:OAT+IgGFoodAllergyTestw/Candida
HAIRKIT
+MetalsHair+PhospholipaseA2ActivityTest
GPL4Serum:OAT+IgGFoodAllergyTestw/Candida
MetalsHairTest
+RedBloodCell+PhospholipaseA2ActivityTest

COMPREHENSIVETESTPANELS
ComprehensiveAutismPanel
ComprehensiveAD(H)DPanel
ComprehensiveTourettes&TicsPanel
ComprehensiveFibromyalgia&CFSPanel
ComprehensiveWellnessPanel
ComprehensiveMentalHealthPanel

BASICTESTPANELS
BasicAutismPanel
BasicAD(H)DPanel
BasicTourettes&TicsPanel
BasicFibromyalgia&CFSPanel
BasicWellnessPanel
BasicMentalHealthPanel

Additional Resources Available on Our Website


Free Webinars
The Great Plains Laboratory, Inc. uses the power of the internet to bring educational conferences into the comfort of your
home. These webinars are educational seminars conducted by a wide range of experts on the topic of biomedical treatment
and testing. The information is designed to provide useful information about the clinical manifestations that occur in certain
disorders. The presenters draw from years of clinical experience to bring you important, helpful information about various
situations that can occur in the body to create illness and disease. The presentations explain the topic in detail using language
that is easy to understand. These live webinars are given frequently throughout the year. Specific dates can be found listed on
the Upcoming Webinars section of our home page.

Sign Up to Receive Email Updates


Emails will include information regarding new and updated tests, conferences, and webinars. A special publication called
BioMed Today E-Newsletter is sent out quarterly in addition to the e-mails and includes a featured topic and related
articles about new and updated discoveries in the biomedical field as well as upcoming events, discussions, tips, recent
news, and other resources. Visit E-mail Sign Up under Upcoming Events on our website to sign up.

Books and DVDs


We offer a variety of educational books and DVDs including Dr. Shaws books: Biological Treatments for Autism and
PDD and Autism: Beyond the Basics. To place an order, go to GPL Bookstore under Resources on our website.

Integrative Medicine for Mental Health (IMMH) Clinician Registry & Resources
Integrative medicine for mental health is a whole body approach utilizing multiple fields of medicine and nutritional
sciences. The Integrative Medicine for Mental Health website contains a Registry where medical professionals are listed
as resources to the community. Clinician Registry eligibility is exclusive to practitioners who have either attended an
IMMH Conference or after viewing the IMMH Conference DVD. Visit www.IMMH.org for more information.

Educational Conferences
The Great Plains Laboratory, Inc. regularly hosts, sponsors, and attends conferences around the world. These events
provide patients and practitioners with the opportunity to learn more about the latest research and the clinical significance
of tests and treatments. The conferences hosted by GPL provide an opportunity to learn about the complex metabolic
pathways that are affected in particular disorders, and about environmental and genetic influences that are contributing to
the symptoms of disease. To find out where GPL is participating in a conference, visit Upcoming Events on our website.

Clinician Educational Seminars


The Great Plains Laboratory, Inc. frequently hosts clinician educational seminars designed to improve the scope of
practice. We provide useful tools for practitioners to understand the various influences that complicate metabolic
pathways and explain the connection in our test results. Using the latest research on specific compounds and metabolites,
we bring new insight to the disease process. The practitioner will gain an understanding of the clinical significance of
biomedical testing and a clear comprehension of the appropriate treatment. To find out when and where our next clinician
educational seminar will be held, visit Upcoming Events on our website.

Sample Patient Health History Form


This is a template available for you to use to obtain patient information and assess overall health.

Four Weeks to Dairy-Free


This educational resource is to help those who are trying to embark on a casein-free (CF) or dairy-free diet. The guide
contains information on how to get started, a list of foods that contain casein and their alternatives, recipes, meal ideas,
and more. The daily instructions included in the guide can provide a smooth transition to a dairy-free lifestyle.

Patient Price List


This resource is available for download. When placing kit orders, you can request sets of 12 for waiting room material.

Getting Started with Lab Testing

Brochures Available on Our Website


Test Brochures
William Shaw, Ph.D., Director

Upgraded Organic Acids Test


Now With Additional Markers
The Organic Acids Test
The Organic Acids Test (OAT) provides
a metabolic snapshot based on the
products the body discards through the
urine. These small, discarded organic
acid molecules are byproducts of human
cellular activity, the digestion of foods, and
the metabolism of gastrointestinal flora.
At certain levels, organic acids in urine
may be indicators of toxicity or markers
of the function of metabolic pathways.
Levels of yeast or gastrointestinal bacteria
metabolites are compared to normal
levels of human metabolites, providing an
assessment of yeast and bacterial activity.
The Organic Acids Test includes 74 urinary
metabolites (including creatinine) and two
neurotransmitter ratios. Recently, two new
markers of genetic disease were added to
the panel, one of which has been linked to
autism.

(913) 341-8949

Fax (913) 341-6207

www.GPL4U.com

Oxalate Control

Understanding IgE Reactions

levels of organic acids in their


system. Factors which can cause
or affect the intestinal yeast
overgrowth include oral antibiotic
use, excessive sugars in the diet,
selective or combined immune
deficiencies, genetic and other
factors.

Patients and physicians have reported


significant improvement upon treatment
including: decreased fatigue, regular
bowel movements, increased energy
and alertness, increased concentration,
improved verbal skills, less hyperactivity,
better sleep patterns, and decreased
abdominal pain.

Besides the new markers, the OAT still


evaluates other important compounds
including Krebs cycle metabolites and
neurotransmitters. This reliable test detects
the overgrowth of yeast and a bacteria
species, Clostridia, commonly missed
by conventional culture methods. These
organisms and their metabolites can
produce or magnify symptoms of many
medical conditions. Identification of a
yeast or bacterial overgrowth paired with
a successful treatment can increase the
probability of recovery.

AD(H)D

Alzheimers Disease

Anxiety Disorders

Aspergers Syndrome

Autism Spectrum Disorders

Chronic Fatigue

Colitis and Crohns Disease

Depression

Down Syndrome

Endometriosis

Fibromyalgia

The Importance of IgE Testing


Elimination of IgE-positive foods and reduction of exposure to inhalant allergens can
bring about major improvements in many symptoms and disorders triggered by food
and environmental sources. The Great Plains Laboratory, Inc. (GPL) offers both basic
and advanced serum tests for specific IgE antibodies to a wide range of allergens.
The advanced tests of 93 foods and 69 inhalants increase the probability that
a patient may identify numerous allergy triggers. In the IgE Inhalant Allergy
Advanced Test, we have included Candida and Thimerosal markers.

Learning Disabilities

Movement Disorders

Multiple Sclerosis

Obsessive Compulsive Disorder


Recurrent Infections

Tic Disorders
Tourette Syndrome

(continued on page 2)

Although IgE allergies are associated with immediate and therefore easily
discernible reactions, not all IgE responses are so clear. Testing is an important
adjunct to the patients symptom reporting in identifying triggers.

http://patienteducation.upmc.com/Pdf/
LowOxalateDiet.pdf

Test results show which foods and inhalants are associated with elevated
IgE antibodies that may cause reactions. These results help guide health
practitioners in customizing therapies for their patients.

Gastrointestinal Disorders,
Diarrhea or Constipation

I believe the Great Plains


IgG Food Allergy Test is
a phenomenal tool that I

A free phone consultation with our nutritional consultant


is available to practitioners and patients with physician
approval.

practice on a daily basis


to help treat patients
for a wide variety of
symptoms like headaches,

Better receptive and expressive

IBS, fatigue, abdominal

language

pain, dermatitis, hair loss,

Increased imitation skills

joint pain, acne, thyroid

Increased sociability

disorders, and vitamin

Decreased rigidity

deficiencies. I believe I am

Better sleep

a better physician due to

Reduced self-abusive behavior

this testing transforming

Increased imaginary play

Oxalates in the urine are much higher in


individuals with autism than in normal children
(Figure 1). As a matter of fact, 36% of the
children on the autism spectrum had values
higher than 90 mmol/mol creatinine, the
value consistent with a diagnosis of genetic
hyperoxalurias while none of the normal
children had values this high. 84% of the

Easy to Understand Results

have implemented in my

Benefits reported by parents


using low oxalate diet
according to Susan Owens
Improved gross and fine motor skills
Better counting ability

36% of the children on the autism


spectrum had values higher than 90 mmol/
mol creatinine, the value consistent with
a diagnosis of a genetic hyperoxaluria.

my ability to properly

Improved cognition
Decreased bed wetting

diagnose and treat patients

Less frequent urination

effectively.

Improved handwriting

Bridget, M.D.

Less fatigue and more energy


And many others

Organic Acids Test - Oxalates

Organic Acids Test

For more information or to request a test kit, contact us


Phone: (913) 341-8949 Fax: (913) 341-6207 Toll Free: 1-800-288-0383
www.greatplainslaboratory.com E-mail: customerservice@GPL4U.com

OAT Oxalates Brochure


06/05/13

IgE Food & Inhalant Allergy Tests

Page 1

Organic Acids Test Brochure


8/22/12

Oxalates and Autism


A brand new diet is being extensively used to
treat children with autism and other disorders.
Oxalate and its chemically similar form oxalic
acid are widely used in industry. A researcher
named Susan Owens discovered that the use
of a diet low in oxalates markedly reduced
symptoms in children with autism and PDD.
For example, the mother of an autistic son
reported that he became more focused and
calm, that he played better, that he walked
better, and had a reduction in leg and feet pain
after being on a low oxalate diet. Prior to the
low oxalate diet, her child could hardly walk
up the stairs. After the diet, he walked up the
stairs very easily. Many hundreds of children
with autism throughout the world are now
being placed on this diet with good results.

06/18/14

gE Food & nha ant


A ery Tests

Organ c Ac ds Test
OAT

Page 1

11813 West 77th Street, Lenexa, KS 66214

(913) 341-8949

Fax (913) 341-6207

(913) 341-8949

Fax (913) 341-6207

www.GPL4U.com

Human IgG is separated into four subclasses denoted IgG1, IgG2, IgG3, and IgG4.9
Each subclass varies in abundance and biological function. IgG1 and IgG3 are
predominantly responsible for antibody protection against reinfection. IgG2
antibodies are opsonic (marking a pathogen for ingestion and destruction) and
develop in response to carbohydrate polysaccharide antigens. IgG4 molecules
function as skin-sensitizing immunoglobulins and are thought to block antibodies
produced in response to chronic exposure to antigens.

Antigen Binding Sites

Fab Region

Fc Region

Immunoglobulin
Figure 1 Structure

Clinical Usefulness

(913) 341-8949

Our two test options, plasma and urine amino acids


analyze 40 amino acids and provide a detailed explanation
of the causes and possible consequences of detected
abnormalities, along with nutritional recommendations.
By using The Great Plains Laboratory, Inc. you will receive the benefits
of testing and free consultations with experts, ongoing free e-mail
and phone support, high quality control, detailed explanation of
results, and easy testing procedures.

Most people receive substantial vitamin D through sunlight exposure. Vitamin D


can also come from supplementation and diet; however, there are very few foods
that naturally contain vitamin D. Some foods that contain vitamin D are fatty fish,
fish liver oil, and eggs.
The Vitamin D Test at The Great Plains Laboratory, Inc. can help to determine if
sun exposure is adequate, if dietary vitamin D is sufficient, and can assess the
likelihood of malabsorption or liver disease.

Vitamin D Deficiency By Population


The NHANES provided data on the vitamin D nutritional status of the US
population. Approximately 9% of the pediatric population, representing
7.6 million US children and adolescents, were vitamin D deficient, and 61%,
representing 50.8 million US children and adolescents, did not have optimal levels
of vitamin D. Generally, younger people had higher vitamin D levels than older
people, males had higher levels than females, and non-Hispanic whites had higher
levels than Mexican Americans, who in turn had higher levels than non-Hispanic
blacks. Depending on the population group, 1-9% had levels <11 ng/mL, 8-36%
had levels <20 ng/mL, and the majority (50-78%) had levels <30 ng/mL.

Amino acids
are the building
blocks of all
structural proteins
essential for life.

Test Description
The Vitamin D Test is available in a dried blood spot (DBS) or as a serum assay that
quantitates 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 metabolites. The
metabolite 25-hydroxyvitamin D is the major circulating form of vitamin D in
the body and the best indicator of a patients true vitamin status due to its long
half-life of 2-3 weeks. The major biologic function of vitamin D is to maintain the
normal blood levels of calcium and phosphorus involved in bone mineralization.
Vitamin D also influences expression of more than 2,000 genes, including those
responsible for regulation of cellular proliferation, cell differentiation, apoptosis,
1

Fax (913) 341-6207

Vitamin D

Even with a very


complete and
balanced diet,
nutrients have
to be properly
digested to
transport vitamins
to different parts
of the body.

The Great Plains Laboratory, Inc. can check metal levels in hair, urine, blood, and
stool, using samples appropriate for each specific situation.

Determining the Best Testing Method


Hair is ideal for the initial evaluation because of easy sample collection procedures,
accuracy, and economic price. As blood transports metals to body tissues and hair
follicles, toxic elements get incorporated and excreted in the hair tissue.

Levels of healthy bacterial flora versus


presence of potentially pathogenic bacteria
species, yeast and parasites
Culture and sensitivities of pathogenic yeast
and bacteria

Estrogen
Estradiol
Estriol
Estrone
Progesterone

Osteoporosis
Poor Immunity
Sleep Disorders
Tic Disorder
Tourettes Syndrome
Weak Nails

11813 West 77th Street, Lenexa, KS 66214

(913) 341-8949

Fax (913) 341-6207

Testosterone
DHEA
Cortisol

Measuring hormone levels is an important proactive step in health


maintenance. Many vague symptoms result from hormone imbalance and
can be treated if properly identified.

Symptoms of the reproductive and menopausal years


Breast pain and/or tenderness
Cysts and lumps (breast, uterine)
Fibrocystic breasts
Depression / insomnia

Irregular menstrual cycles


Hot flashes
Weight gain
Brain fog

Why is male sex hormone balance important?


Hormone Markers:
Testosterone
Estradiol
Progesterone
DHEA
Cortisol

Clostridium Difficile

Infectious pathogens: ( EIA evaluation for


Campylobacter, Enterohemorrhagic E.coli
cytotoxin, Giardia lamblia, Cryptosporidium)
Indices and markers of intestinal immune
function (fecal sIgA)

Testosterone is the primary male sex hormone and is released in pulses


throughout the day. Testosterone production rises during puberty. After 35, free
testosterone becomes less available due to increased testosterone-binding
proteins and decrease in testosterone-releasing cells. Low testosterone levels
or high stress in mens early 20s or 30s may cause symptoms similar to going
through the natural decline of testosterone.
DHEA is the precursor to both female and male sex hormones, as well
as to the stress hormone cortisol. The balance of testosterone with other
estrogens, progesterone, DHEA, and cortisol influences mens health. Higher
estrogen levels with low testosterone levels have been correlated with an
increased risk of prostate problems. High cortisol and DHEA can increase
anxiety, lower immunity and destablize blood sugar, as well as the risk of
cardiovascular disease.

Symptoms of declining testosterone:

Indices and markers of inflammation


(lysozyme and lactoferrin levels)

Erectile dysfunction
Decrease mental ability
Insulin resistance
Decreased sex drive

Indices and markers of intestinal physiology


and of intestinal health (presence of RBC,
WBC, mucus, occult blood, fecal pH, and
short chain fatty acids analysis).
1

Lethargy
Weight gain
Difficult Urination
Prostate enlargement

Decline in muscle
strength and mass
Bone loss

ng/dl
1000
800
600
400
200
0

20 25 30 35 40 45 50 55 60 65 70

Decline in testosterone by age

Hormone Health & Your Body

11/26/13

Comprehens ve
Stoo Ana ys s

Hormones

Essent a Fatty Ac ds

Disorder Brochures

sonalized Testing and Treatment

cal routine lab work often falls short of uncovering


le abnormalities which can have a profound effect
ealth. Unless accurately addressed, this vicious cycle
continue to inhibit the various biochemical pathways
ssary for proper neurological and immune function.
resulting complications contribute to, and may even
e, the symptoms of autism.

chieve optimal results, it is critical that potential


medical issues be assessed and included as part
he overall treatment programs for individuals
h autism spectrum disorders.

school, work, or home, resulting in academic or professional


based clinical laboratory offering testing for nutritional
failures,
factors in chronic illnesses such as autism, ADD,
andpoor social skills, low-self-esteem, depression, antisocial
behaviors, or substance abuse.
fibromyalgia. We provide a variety of metabolic
tests
such as immune deficiency evaluation, amino acid,
AD(H)D is considered to be a persistent and chronic
essential fatty acid, cholesterol levels, metal toxicity,
condition for which biomedical intervention can be helpful.
and food allergy tests.
Once the biological causes of AD(H)D are addressed, it may
possible to reduce or eliminate drug therapy.
Recommended Tests for Autism Spectrum be
Disorders:
Advanced Cholesterol Profile
Comprehensive Stool Analysis
Copper/Zinc Profile
Ferritin Test
Gluten/Casein Peptides Test

mprehensive laboratory testing can identify the


siological imbalances that contribute to autism
point to an individualized treatment approach.
tments are designed to restore the body to
nce and optimize function through nutritional
port, diet, detoxification, and reduction of toxic
ronmental influences.

Evaluating the Patient


The Great Plains Laboratory,
Inc. is dedicatedAutism
to assisting
Understanding
healthcare practitioners make a difference by helping The integrative approach to evaluation and treatment
Traditionally, the diagnosis of autism has been based
children, adults, and families achieve their maximum
of and
physical
and psychological
symptoms begins with
on the observation of behavior,
treatment
focused
potential through quality laboratory testing. Our
identifying
multiple
underlying factors that may
primarily on alleviating challenging
behaviors.
However,
laboratory provides the most reliable, comprehensive,
there is a very real biomedicalbe
component
to the
disorderinflammation, immune
responsible:
digestion,
and understandable scientific results, using the latest
in which underlying medical issues
oftenhormone
cause orlevels, oxidative stress, toxicities,
reactions,
technology and proven techniques.

Without treatment, AD(H)D can lead to profound distress at


The Great Plains Laboratory, Inc. is a research-

IgG Food Allergy Test w/ Candida


Immune Deficiency Profile
Metals Hair
Organic Acids Test
Streptococcus Antibodies Profile
Vitamin D Test

AD(H)D

Autism Spectrum
Disorders

contribute to autistic behavior.


microbial infections, and the psychological and spiritual
state of the individual.
Some of the most common problems include gastroRecommended
Tests
forovergrowth
AD(H)D: of Candida and Clostridia,
intestinal
(GI)

Address the Underlying Causes of AD(H)D

Advanced Cholesterol
Profito
le detoxify environmental toxins, and
inability
Many children with AD(H)D have one or more of the following
development
of food intolerances and/or allergies.
Amino Acids Urine
Test
nutritional or metabolic
imbalances:autism
mineral and
vitamin testing, diet,
Treating
through
These
physical
factors limit
thein 50 Americans are estimated
Comprehensive Fatty
Acids
Test and environmental
Approximately
one
deficiencies, toxic metal accumulation, improper diet, hidden
nutrients
available to the brain and body, resulting
and
supplementation
Comprehensive Stool
Analysis
to have fibromyalgia, or between 3 and 6 million
infections, chronic yeast
overgrowth,
or food sensitivities.
in damage to cellular, metabolic, and central nervous
Copper / Zinc Profile
people in the U.S.
system functioning.
Methods of treatment should involve a combination of
Ferritin Test
biomedical treatments, nutritional supplementation, and
- American
College
of Rheumatology
Every individual
with autism exhibits
unique
behavioral
Gluten / Casein Peptides
Test
diet modification. This treatment can be implemented
and w/
cognitive
IgG Food Allergy Test
Candidasymptoms with varying degrees of severity.
in conjunction with behavior modification, medication,

It isfrom
necessary
towe
care
for the whole patient, not just the
children and
adults
suffering
AD(H)D,
have
The Great PlainsIn
Laboratory,
Inc.
is a research-

found profound
nutrient
ciencies
biochemical
disease.and
An evaluation
of each patients biochemistry and
based clinical laboratory
offering testing
fordefi
nutritional
abnormalities.
science
is now
available
to explore
nutritional
needs
is essential for effective treatment. The
factors in chronic illnesses
such asThe
autism,
ADD,
and
these unique
metabolic
profiles
andisbegin
to understand
goal
to restore
health for the long-term, not just reduce
fibromyalgia. We provide
a variety
of metabolic
tests
ourciency
individualized
biochemical
fingerprints. Treating
symptoms.
such as immune defi
evaluation,
amino acid,
the underlying biochemistry addresses the core of the
essential fatty acid, cholesterol levels, metal toxicity,
problem. I believe this is preferable
to only
providingbegins with an analysis of the
Treatment
of
depression
hormones, and food allergy tests.
temporary relief of symptomspatients
throughbiochemical
medication.
profile, focusing on any abnormalities

I had fibromyalgia/chronic
syndrome (FM/CFS)
The Great Plains Laboratory,
Inc. is dedicatedfatigue
The Nutritional
Approach to Treating
suffered with
problems,
varying degrees
to assisting healthcareand
practitioners
makedigestive
a difference
Eating Disorders
of pain,
by helping children, adults,
andanxiety,
familiesdepression,
achieve theiretc., for more than 13
Every treatment plan needs to be specific for each
years. Every
after
work I was exhausted. Some
maximum potential through
qualityevening
laboratory
testing.
individual and should start with a comprehensive
days
wasnt
able to
go to work. Now, I have been
Our laboratory provides
theImost
reliable,
comprehensive,
biochemical evaluation. Then the nutrition-based
mostlyc symptom-free
more than three years and
and understandable scientifi
results, using thefor
latest
treatment can be implemented in conjunction
have
lots of energy.
technology and proven
techniques.

Fibromyalgia
& Chronic Fatigue

Depression

with traditional treatments, including individualized

The Great PlainsDepression


Laboratory, Inc. is dedicated to
assisting healthcare practitioners make a difference
Depression is a collection of unpleasant emotional and
by helping children,
adults, and families achieve
physical symptoms that can be disabling. The underlying
their maximum potential
through
quality
issues that
contribute
to laboratory
depression are different in each
testing. Our laboratory
provides
thebe
most
reliable,
patient
and must
identifi
ed to effectively treat the
comprehensive, and
understandable
scientific results,
disorder.
Potential contributors
include: sleep disorders,
using the latest technology
and proven
techniques.
toxic chemical
exposure,
poor digestion, food allergies /

Resources, Inc.

Amino Acids Urine Test

C-Reactive Protein
WhatTest
is AD(H)D?

Addressing the underlying causes


of AD(H)D

Metals Hair Test Common symptoms can also include eczema, diarrhea,

lifestyle change, and counseling to help the patient achieve


maximum potential.

constipation, rashes, dark eye circles, and visible stomach


pain.[1]

Organic Acids Test

Streptococcus Antibodies Profile

Our laboratory provides the most reliable, comprehensive,


and understandable scientific results, using the latest
technology and proven techniques. Free webinars are
available on our website.

Vitamin D Test

technology and proven techniques.

Evaluating the Patient


Clinical assessment of a patients symptoms, a thorough
medical history, and appropriate laboratory testing are the
foundation for an effective treatment plan that can lead to
customerservice@GPL4U.com
restoration of a normal life.
www.GPL4U.com
(913) 341-8949
Fax (913) 341-6207

customerservice@GPL4U.com
(913) 341-8949
Fax (913) 341-6207

customerservice@GPL4U.com
(913) 341-8949
Fax (913) 341-6207

from341-8949
these illnesses, remember there is hope. It
(913)
Read
the article
at: www.immh.org/anorexia
isnt the diagnosis that you
should
be concerned
Fax (913) 341-6207
with, but rather the things you can change.

www.GPL4U.net

www.GPL4U.net

www.GPL4U.net

AD H D

Aut sm Spectrum
D sorders

William Shaw, Ph.D., Director

11813 West 77th Street, Lenexa, KS 66214

(913) 341-8949

Fax (913) 341-6207

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Inattention

Facial grimacing

Obsessive-compulsive
symptoms such as intrusive
thoughts or worries and
repetitive behaviors

Shoulder shrugging
Head or shoulder jerking

F bromya g a &
Chron c Fat gue

Cholesterol Balance
Deficiency & Excess
Low cholesterol has been connected to
depression, anxiety, bipolar disorder and
statistically higher frequency of violent
behavior, suicide, Parkinsons disease,
and cancer mortality. Susceptibilities to
tuberculosis and gastrointestinal infections are
also associated with lower cholesterol levels.
Most significantly, the death rate is doubled in
older adults with lower total cholesterol and
stroke and cataracts rates are higher.

Hyperactivity and impulsivity

Perhaps the most dramatic and disabling tics are those that result in self-harm
such as punching oneself in the face, or vocal tics including coprolalia (uttering
swear words) or echolalia (repeating the words or phrases of others).
Early symptoms of TS are almost always noticed first in childhood, with the
average onset between the ages of 7 and 10. TS occurs in all ethnic groups,
and males are affected three to four times more often than females. Although
TS can be a chronic condition with symptoms lasting a lifetime, most people
with the condition experience their worst symptoms in their early teens, with
improvement occurring in the late teens and early adulthood.

Cholesterol is a sterol essential to life and


is found in every animal cell. Cholesterol is
part of our cellular structure and protects our
tissues. Many people fear and focus on high
cholesterol levels, yet never focus on low
cholesterol levels, which can have negative
health effects. Like everything in nature,
balance is the key.

An estimated 200,000
Americans have a severe
form of TS, and as many
as one in 100 individuals
exhibit milder and less
complex symptoms

High cholesterol is statistically associated with


greater risk of cardiovascular disease (CVD),
but less well known is the association of low
cholesterol with poor health and many chronic
disorders. Recent studies have suggested
strongly that lower cholesterol does not
guarantee a long life or high quality of life.

What is Tic Disorder?


Chronic tic disorder, also known as Chronic Motor Tic Disorder involves quick,
uncontrollable movements or vocal outbursts. The condition is more common
than Tourettes syndrome; however, it is not common as transient tic disorder.
Transient tic disorder is a temporary condition in which a person makes one
or many brief, repeated, difficult-to-control movements or noises (tics). Often
considered a mild form of Tourettes syndrome, tics look like nervous behavior,
appear to get worse with stress, and do not occur during sleep.

The Great Plains Laboratory, Inc. (GPL) offers


the Advanced Cholesterol Profile. This profile
is used to determine whether a cholesterol
deficiency is present or if cholesterol is
elevated. This profile also determines if
the body is eliminating potentially toxic
homocysteine and determines risk factors for
vascular disease and/or neurological disease.

Tourette
& Tic
Disorders

What is OCD?
Obsessive-Compulsive Disorder (OCD) is an anxiety disorder
characterized by recurrent, unwanted thoughts (obsessions) and/ or
repetitive behaviors (compulsions). The relationship between OCD
and Tourettes syndrome is well documented and was included in the
original description of TS reported in 1885. Modern-day literature supports
the genetic relationship between TS and OCD also, with the percentage
of OCD in TS reported ranges from 30% to 90%. Interestingly, the clinical
features in patients with TS often appear different than in patients with primary
OCD; for example, the manifestation of images and impulses tend to be sensory
issues such as concern with appearance, fear of saying or doing something
wrong, need to know or remember, and self-injurious behaviors. These
differences have led several researchers to conclude that TS + OCD is more
closely related to TS and may represent a subset of the disorder.

ADHD

Tourettes Syndrome, Tic Disorder, & OCD


07/26/13

contribute to depression and point to an


individual treatment approach to restore
normal mood.

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www.GPL4U.net

Depress on &
B po ar D sorder

Eat ng D sorders

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What is Tourettes Syndrome?


Tourettes syndrome (TS) is a neurological disorder characterized
by repetitive, stereotyped, involuntary movements and vocalizations
called tics. Many individuals with TS experience additional
neurobehavioral problems. Some characteristics include:
Eye blinking and other vision
irregularities

customerservice@GPL4U.com
Comprehensive laboratory testing can
(913) 341-8949
identify the physiological imbalances that
Fax (913) 341-6207

www.GPL4U.net

Tourettes Syndrome, Tic Disorder, & OCD

OCD

Benefits of Cholesterol
Cholesterol serves several important roles
in metabolism: it is a key constituent of all
cell membranes and provides the structural
framework of vitamin D and adrenal and sex
hormones, as well as for bile acids which
help digest fat and increase absorption of fat

Depression

soluble vitamins. Most cholesterol is made in


the liver and is so crucial to metabolism that,
if necessary, it can be synthesized from either
fatty acids or glucose.

The Brain is the Most Cholesterol-Rich


Organ in the Body
Cholesterol synthesized in the brain is the
primary component of the myelin that surrounds
each nerve cell as a protective sheath. Loss of
myelin from disease or injury inevitably causes
neurological damage. Both neurons and glial
(support) cells in the central nervous system
(CNS) contain unbound cholesterol as an
integral part of their cell membranes.

Low Cholesterol Associated with


Mental Disorders & Mortality in Elderly

Cholesterol & Cardiovascular Disease


High cholesterol may be associated with
the onset of CVD, but cholesterol may be
deposited as a patch on inflamed or injured
blood vessels, particularly coronary arteries.
Macrophages scavenge cholesterol along
with other cell debris and may become foam
cells which accumulate in artery walls and
cause atherosclerotic streaks. Assessments of
inflammation such as C-reactive protein (test
available at GPL) or homocysteine level have
been suggested as better predictors of CVD
risk.

Understanding the health consequences of


lower cholesterol has been aided by studying
serious genetic disorders that prevent
cholesterol synthesis in the body. Low cholesterol has been connected to greater risks
of suicide, accidents, violence, and mood
disorders, such as depression.
Cholesterol levels may influence serotonin
activity in the brain. Serotonin is the
neurotransmitter associated with mood,

Homocysteine (Hcy) is a non-protein, nonstructural amino acid that is generated by


metabolism of methionine, an essential amino
acid. Homocysteine can be recycled back to
methionine with folic acid and vitamin B-12 as
co-factors.

Tourette s T c & OCD

Getting Started with Lab Testing

underlying

and bacterial problems, I started feeling better than


I had felt in years. I found outClinical
that eating
organically
Treatment
of Anorexia Nervosa
grown foods and meats free Merits
of antibiotics
growth- by James Greenblatt, M.D.
More and
Attention
hormones is important. Also, vitamins, minerals, and
More than 30 percent of patients with anorexia nervosa
herbal supplements played a role in my recovery.
become chronically ill within 10 years. Ten percent die
within 10 years and 20 percent die within 20 years. We
If you are among the millions
of people
who
suff
er
customerservice@GPL4U.com
should
do better
than
prescribing
drugs that dont work.

- Yvonne Keeny, Executive Director, Fibromyalgia Coalition


International

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Individuals with eating disorders have the highest


mortality rates out of all the mental illnesses. In the
U.S., as many as 10 million women and 1 million men
battle anorexia or bulimia, and many others struggle
with binge eating disorder or compulsive overeating.

Eating Disorders

sensitivities, nutritional deficiencies, immune reactions,


medications and therapy if needed.
that may be contributing to symptoms. Test results can help
After trying the drug route, I researched non-drug
levels,
oxidative
stress,
inflammation, and the
Beneficial Tests for Patients with Depression
Tests Beneficial hormone
for Patients
with
Eating
Disorders
medical practitioners create a treatment plan designed to
solutions and found out many existed.
psychological and spiritual state of the patient.
Advanced Cholesterol Profile
Advanced Cholesterol Profile
A nutritional approach transforms the treatment
restore balance and optimize function through nutritional
eating disorders
from conventional
hit-or-miss
support and diet. This integrative approach can enhance
Amino Acids Plasma
Testhelped even more wasofI learned
Amino Acids Plasma Test
physiological
imbalances that
Understanding the complete
What
aboutIdentifying
the yeast
Understanding and evaluating nutritional
Is Depression an Epidemic?
Comprehensive Stool Analysis
and reinforce traditional
trials to individually focused interventions
Comprehensive Fatty
Acids TestI contacted Themedication
Comprehensive Fatty Acids Test
AD(H)D is a neurobehavioral developmental
disorder treatment methods, increasing the
connection.
Great
Plains
Laboratory,
contribute to depression
causes of eating disorders
factors in fibromyalgia and chronicfatigue
chance
of recovery.
Depression
has a profound impact on society. According
based on laboratory analysis.
Gluten/Casein
Peptides
Test
Comprehensive Stool
that
typically
presents itself during
childhood
and is
Comprehensive
Stool Analysis
Inc. Analysis
and asked for a physician referral to do the testing.
to the
characterized
by a persistent pattern of inattention and /
IgG Food Allergy
Test w/ Candida
Copper/Zinc Profile
Copper/Zinc Profi
le World Health Organization, depression is the
I did have a yeast overgrowth plus a bacterial infection
leading cause of disability in the U.S. for people ages 15or hyperactivity, as well as forgetfulness, poor impulse
Metals Hair Test
Gluten/Casein Peptides
Gluten/Casein Peptides Test
in my Test
gastrointestinal tract. I discovered I was sensitive
44. Depression can affect anyone but is most common in
control, and distractibility. About 60% of children diagnosed
to house
dust, certain foods, molds, and chemicals.
IgG Food Allergy Test
w/ Candida
IgG Food Allergy Test w/ Candida
Organic Acids Test
women.
Mental
Health
America
reports
$31
billion
worth
with AD(H)D retain the condition as adults. Many cases
Metals Hair Test Also, I had hypothyroidism and some hormonal and
Metals Hair Test
Vitamin D Test
of productive time is lost each year to depression among
may be caused by trauma, toxic exposure, food allergies or
Organic Acids Testmineral deficiencies.
Organic Acids U.S.
Testworkers. Mood-altering drugs are being dispensed at
intolerances, or nutritional deficiencies.
Our laboratory provides the most reliable, comprehensive,
Vitamin D Test
Vitamin D Testrecord levels. Unfortunately, antidepressants do not work for
Within a few weeks of starting treatment for the yeast
and understandable scientific results, using the latest
everyone and many have frequent, unwanted side effects.
James Greenblatt, Director of Comprehensive Psychiatric
Recommended-Dr.
testing
for Fibromyalgia include:

Cho estero
De c en y &
Chron c D sorders

www.GPL4U.com

As girls mature to women, hormonal changes


orchestrate the process leading to the beginning
of menstruation. There are two phases during
a womans menstrual cycle, the first phase
is considered the estrogen-dominant phase
(prior to ovulation), and the second phase
is progesterone-dominant (post-ovulation).
The monthly shifts between estrogen to
progesterone are crucial to a womans health.

DHEA is the precursor to both female and male sex hormones and is
released with cortisol under stress conditions.

Candida Albicans

06/18/14

Heavy Meta s

Seizures

Muscular Weakness

Women normally produce small amounts of testosterone. This male


hormone helps women stay strong, fit and sexually active, and may protect
against breast cancer and cardiovascular disease.

Comprehensive Stool Analysis

Heavy Metals Testing


06/18/14

Obsessive-Compulsive
Disorder

William Shaw, Ph.D., Director

The Comprehensive Stool Analysis detects the presence of pathogenic yeast,


parasites, and bacteria, which could be contributing to chronic illness and
neurological dysfunction. It provides helpful information about prescription and
natural products effective against specific microorganism strains detected in the
sample. The test also evaluates beneficial bacteria levels, intestinal immune
function, overall intestinal health (presence of occult blood, short chain fatty
acids analysis, pH, mucus, and other criteria), and inflammation markers.

Elimination efficiency of undigested food


residues and toxins

Inborn Errors of Metabolism


Kidney Stones
Movement Disorders

Our dedication to customer service shows that we


care about our clients continuous well-being and
progress after doing our tests.

Hormone Markers:

About the Test

Absorption of nutrients (cholesterol,


carbohydrates, steatocrit %)

Failure to Thrive
Gastrointestinal Problems

Why analyze female sex hormones?

For example, excessive yeast produces toxic metabolites, which can pass
through the blood-brain barrier and alter neurological functioning causing
brain fog, behavior problems, and learning difficulties. Exposure to certain
pathogens can cause the formation of antibodies that can interfere with the
brain in predisposed individuals, causing problems with motor function. Excess
of toxic by-products of certain bacteria can interfere with neurotransmitters
and cause fatigue. Beneficial bacteria, on the other hand, helps with vitamin
absorption and preventing infections.

Nutrients digestion (chymotrypsin,


triglycerides, muscle fibers, vegetable fibers)

Urine and fecal tests are most sensitive after taking a chelating agent. Chelating
agents help extract heavy metals deposited in the tissues and bone. These tests
are also important for evaluating the efficiency of chelating treatments since they
measure levels of metals excreted from the tissues during the chelation. Urine and
fecal element tests are not recommended unless using a chelating agent before
sample collection.

Dermatitis
Chronic Fatigue

Checking levels of amino acids is an integral part of any metabolic


and nutritional evaluation. Low levels of amino acids can increase
the susceptibility and risk of various diseases, complicate healing
processes, and cause fatigue and general discomfort.

The Importance of Understanding Hormone & Bodily Changes

Comprehensive Stool Evaluation Will Give You Specific


Information About The Following Digestive Criteria:

The blood test is best for detecting recent heavy metals poisoning and for
measuring levels of minerals in the body.

Cardiovascular Problems

Amino acid imbalances are frequent underlying causes of metabolic,


as well as gastrointestinal, neurological, and movement disorders.

Hormone Health & Your Body

At The Great Plains Laboratory, Inc., you will receive the benefit of testing with
experts, easy testing procedures, detailed test interpretations, and ongoing free
e-mail and phone support.

The hair test also provides exact ratios between nutrients and toxic metals. The
results show levels of 39 toxic and essential elements and 5 ratios.

Depression

Amino acids are the building blocks of all structural proteins essential
for life. They play an important role in neurotransmitter functioning,
cholesterol and carbohydrate metabolism, and inflammatory and
detoxification processes. They also help form glutathione, the main
antioxidant controlling detoxification and neutralizing free radicals in
the body.

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The negative role of abnormal intestinal microorganisms in gastrointestinal


disorders is widely known. However, research also shows the relationship
between the gastrointestinal and other systems in the body, such as the
neurological, hepatic, and immune systems.

It is equally important to measure levels of minerals, which play an essential part


in numerous physiochemical reactions within body cells. These reactions include
receiving nutrients, filtering, emulsifying, absorbing vitamins, transforming
energy, eliminating toxins, and many others. Toxic overload and metabolic
imbalances favor minerals depletion.

What is the Role of Amino Acids in the Body?

Am no Ac ds Test

V tam n D

Many chronic disorders come from digestive problems and inadequate nutrient
absorption. Even with a very complete and balanced diet, nutrients have to be
properly digested to transport vitamins to different parts of the body. Proper
gastrointestinal functioning also ensures elimination of toxic molecules, microbes
and undigested food particles from the body to prevent infections, toxic reactions,
allergies, and other health problems.

Why is Metals Testing Important?

Checking levels of amino


acids is an integral part
of any metabolic and
nutritional evaluation.

Recommended for:
Autism Spectrum Disorders

06/18/14

The Importance of the Comprehensive Stool Analysis

Metals testing is important for measuring toxic metals that can impede
development and normal brain functioning, as well as measuring levels of
minerals essential for normal growth and good health.

www.GPL4U.com

Amino Acids Test

07/09/14

Key to maintaining A Healthy Digestive System

Test results frequently show high heavy metal levels coupled with low mineral
levels in people with developmental and neurological disorders, chronic fatigue,
as well as apparently healthy individuals not feeling at 100 percent.

Fax (913) 341-6207

Our dedication to customer service shows that we care about our


clients continuous well-being and progress.

Specimen Requirements: First morning urine (most concentrated), 5


mL or 1 lavender-top tube of whole blood (overnight fasting).

Comprehensive Stool Analysis:

Many symptoms of heavy metals poisoning are identical to symptoms of


neurological and psychiatric disorders; therefore, it is difficult or impossible to
identify their cause without expert laboratory testing.

(913) 341-8949

The Great Plains Laboratory, Inc. Amino Acids Test offers


important clinical data on metabolic, nutritional, and
neurological disorders, directly or indirectly dependent
on the amino acids levels and metabolism evaluated in
the test.

Vitamin D is essential for the formation, growth, and repair of bones. Vitamin D is
necessary for normal calcium absorption and immune function. It also improves
muscle strength and helps reduce inflammation.

The Vitamin D
Test can help
to determine if
sun exposure
is adequate, if
dietary Vitamin
D is sufficient,
and to assess
the likelihood of
malabsorption or
liver disease.

11813 West 77th Street, Lenexa, KS 66214

Benefits of The Great Plains Laboratory


Amino Acids Test

Approximately 70% of American children do not get enough vitamin D. If


childhood deficiencies are not corrected, they could lead to early development of
diabetes, high blood pressure, cardiovascular disease, or any of several forms of
cancer. Deficiency is also prevalent in infants who are solely breastfed and who do
not receive vitamin D supplementation. Adults of all ages who have darker skin
(increased skin melanin) or who always wear sun protection or limit their outdoor
activities, such as homebound elderly persons, are also prone to vitamin D deficits.

The clinical usefulness of IgG food testing was illustrated in an early article
published by an otolaryngologist who reported that the majority of his patients
had substantial health improvements after eliminating foods found positive by IgG
food allergy testing10. The study demonstrated a 71% success rate for all symptoms
achieving at least a 75% relief. Of particular interest was the group of patients
with chronic, disabling symptoms, unresponsive to other intensive treatments.
Symptoms most commonly improved (75%-100%) on the elimination diets
included asthma, coughing, ringing in the ears, chronic fatigue, headaches, gas,
bloating, diarrhea, skin rash and itching, and nasal congestion. The most common
IgG food allergies were to cows milk, garlic, mustard, egg yolk, tea, and chocolate.
A recent study reported that 93% of non-celiac, gluten-sensitive patients showed
anti-gliadin IgG antibody disappearance after a six-month adherence to a glutenfree diet. The IgG disappearance was closely related to a significant improvement
of both gastrointestinal and extra-intestinal symptoms.11

11813 West 77th Street, Lenexa, KS 66214

William Shaw, Ph.D., Director

Amino Acids Test

Detect the Malfunctioning of Your Bodys Building Blocks

Vitamin D deficiency has been linked to increased risk for many common and
serious diseases, including some common cancers, diabetes, cardiovascular
disease, and osteoporosis. Studies suggest that exposure to sunlight, which
enhances the production of vitamin D in the skin, prevents many chronic diseases.

What is IgG?

William Shaw, Ph.D., Director

11813 West 77th Street, Lenexa, KS 66214

The Most Common Vitamin Deficiency in the US

IgG is the major antibody found in serum. IgGs are composed of two fragment
antigen binding (Fab) regions that contain the antigen binding sites and the Fc
region, which is responsible for most of the biologic activity of the antibodies
(Figure 1). An antigen is a substance that causes the immune system to produce
an antibody that specifically reacts with it. IgG-mediated reactions to food antigens
may be delayed by several hours or days, whereas IgE food antibody reactions are
quite immediate.

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Today, with increasing pollution levels, the presence of toxic metals in the
environment is constantly growing. Chemical products, fertilizers, industrial paint,
building materials, fish, silver dental fillings, and vaccines are just some of the
sources of heavy metals in everyday life. Toxic metals may normally be present in the
body in very low levels, but continuous exposure or metabolic abnormalities can
cause accumulation of heavy metals in body tissues, and subsequently, in the brain.

OAT & Yeast Combo

William Shaw, Ph.D., Director

Vitamin D

gG Food A ergy
Test w/ Cand da

Metals Testing: Hair, Blood, Urine and Fecal

G uten/Case n
Pept des Test

www.GPL4U.com

IgG Food Allergy Tests

Heavy Metals and Your Health

Toxic metals,
can affect
development,
neurological
functioning, and
overall health.

Fax (913) 341-6207

08/19/14

Oxa ate Contro

William Shaw, Ph.D., Director

(913) 341-8949

About IgG Food Testing


Immunoglobulin G (IgG) food testing is a useful guide for structuring elimination
diets for patients with many chronic conditions. Individuals with neurological,
gastrointestinal, movement, and behavioral disorders often suffer from IgG food
sensitivities. People may continue to eat offending foods unaware of their potential
adverse effects. Symptoms associated with food sensitivities may occur hours or
days after the offending food was eaten because IgG food antibodies remain for a
much longer time than traditional IgE antibodies. Elimination of IgG-positive foods
may improve symptoms of irritable bowel syndrome, autism, AD(H)D, cystic fibrosis,
rheumatoid arthritis, and epilepsy, according to numerous clinical studies.1-8 The
93 foods tested for in the IgG Food Allergy Test w/ Candida include most classes
of problem foods that can be eliminated from a patients diet. The Great Plains
Laboratory offers a comprehensive Western food panel as well as an Asian panel. The
Asian panel includes specific foods common to Asian cuisine, such as certain spices
and twice as many seafood items as the Western panel. Sampling requires at least 2
mL of serum or 3 dried blood spots.

Oxalate and its acid form oxalic acid are organic


acids that are primarily from three sources:
the diet, from fungus such as Aspergillus and
Penicillium and possibly Candida (1-9), and
also from human metabolism (10).
Oxalic acid is the most acidic organic acid
in body fluids and is used commercially to
remove rust from car radiators. Antifreeze
(ethylene glycol) is toxic primarily because it is
converted to oxalate in the body. Two different
types of genetic diseases are known in which
oxalates are high in the urine. The genetic
types of hyperoxalurias (type I and type II) can
be determined from the Organic Acids Test
done at The Great Plains Laboratory, Inc. (page
4-5). Foods especially high in oxalates include
spinach, beets, chocolate, peanuts, wheat
bran, tea, cashews, pecans, almonds, berries,
and many others. Oxalates are not found in
meat or fish at significant concentrations. Daily
adult oxalate intake is usually 80-120 mg/d; it
can range from 44-1000 mg/d in individuals
who eat a typical Western diet. A complete
list of high oxalate foods is available on the
internet at:

11813 West 77th Street, Lenexa, KS 66214

IgG Food Allergy Test with Candida

(continued on page 3)

High levels of IgE antibodies indicate that the patient is likely to experience
physiological effects from ingesting foods or inhaling environmental allergens to
which they are sensitive.

Elimination of
IgE-positive
allergens can
bring about major
improvements in
many symptoms.

William Shaw, Ph.D., Director

children on the autism spectrum had oxalate


values outside the normal range (mean 2 sd).
None of the children on the autistic spectrum
had elevations of the other organic acids
associated with genetic diseases of oxalate
metabolism, indicating that oxalates are high
due to external sources.

What are Oxalates?

IgE tests measure levels of the IgE antibodies. When the IgE antibodies bind to specific
receptors of mast cells and other white blood cells, an allergic reaction occurs.

A Major New Factor In Autism Therapy

A classic, or Type I, allergy causes immediate reactions to foods/inhalants


characterized by redness, swelling, and heat in the body as a response to elevated
blood levels of Immunoglobulin E (IgE). IgE is one of several antibody types and
is normally present in very small amounts. Human responses to both food and
inhalant antigens vary widely but increase with production of specific IgE. The
severity of allergic response is due to a combination of genetic background and
extent of exposure to allergens. Exposure to microbes, various foods, and the
surrounding environment may all provoke IgE allergies.

Recommended for the


Following Disorders & Diseases:

Once any abnormalities are detected, there


is a variety of options available to treat the
condition. Treatments include antifungal
or antibacterial products, probiotic
supplementation, vitamins, antioxidants
and dietary modification.

Other Important Markers

Importance of the
Organic Acids Test
The Organic Acids Test (OAT) offers the
most complete and accurate evaluation of
intestinal yeast and bacteria. These factors
are of critical importance in neurological,
gastrointestinal, and movement disorders.
Abnormal toxic metabolites of these
microorganisms can cause or worsen
behavior disorders, hyperactivity,
movement disorders, affect energy levels
and immune function. Yeast can attach
to the intestinal wall causing leaky gut
syndrome, which can cause or magnify
food allergies, impede absorption of
vitamins and minerals, and cause intestinal
disorders. Many people with chronic
illness, allergic conditions, and neurological
disorders often have one or more abnormal

11813 West 77th Street, Lenexa, KS 66214

IgE Food & Inhalant Allergy Tests

New markers, same great quality, same specimen requirements

Cho estero
De c en y & Aut sm

While eating disorders begin as preoccupation with


food and weight, they ultimately become brain-based
disorders of profound malnutrition with extreme
physiological consequences.
A common misperception in the medical community is
that eating disorders are purely psychological and do
not have a biological component. Treatment typically
emphasizes psychotherapy and counseling with little
attention to nutritional deficits that may underlie what
appears to be entirely behavioral.

www.GPL4U.com

customerservice@GPL4U.com

913-341-8949

This innovative and valuable panel by the Great Plains Laboratory (GPL) provides an
excellent and accurate description of the patients overall health in regards to their
metabolism, vitamins and mineral levels, food allergies and metal toxicity. Testing for
organic acids, IgGs, food allergies and metals is crucial to detect any malfunctioning
within the body. With the GPL3 panel, no blood draw is required. Included in the panel are:

Organic Acids Test

Food Intolerance

The Organic Acids Test (OAT) provides a metabolic snapshot based on the products the body
discards through the urine. These small, discarded organic acid molecules are byproducts of human
cellular activity, the digestion of foods, and the metabolism of gastrointestinal flora. The Organic
Acids Test includes 74 urinary metabolites, including 9 yeast markers, 8 bacterial markers, 3 oxalate
markers, 3 Glycolytic cycle markers, 6 Krebs cycle markers, 7 neurotransmitter markers, 1 folate
metabolism markers, 8 fatty acid oxidation markers, 8 vitamin markers, 3 indicators of detoxification,
14 Amino Acid metabolites and 1 bone metabolite. This makes it the most comprehensive Organic
Acids test available anywhere.

IgG Dried Blood Spot - Food Allergies


IgG (immunoglobulin G) testing is a useful guide for structuring elimination diets in many chronic
conditions. Individuals with neurological, gastrointestinal, and movement disorders often suffer
from IgG food allergies. IgG Food allergies do not usually release histamine but cause inflamation
and elevated C-reactive protein. The 93 foods tested in the IgG Food Allergy Test w/ Candida can
identify problem foods so they can be eliminated from the patients diet.

Metals Hair
Gastrointestinal Imbalance

The metals test is important for measuring toxic metals that can impede development and normal
brain functioning, as well as measuring levels of minerals essential for normal growth and good
health. The results indicate levels of 39 toxic and essential elements, 5 ratios and includes an
individualized interpretation.
Today, with increasing pollution levels, the presence of toxic metals in the environment is constantly
growing. Chemical products, fertilizers, industrial paint, building materials, fish, silver dental fillings,
and vaccines are just some of the sources of heavy metals in everyday life. Toxic metals may normally
be present in the body in very low levels, but continuous exposure or metabolic abnormalities can
cause accumulation of heavy metals in body tissues, and subsequently, in the brain.

Value for your money:


Please call your GPL representative to inquire about the different billing options available for the GPL3.

Metal Toxicity

Recommended for the following conditions:


AD(H)D

Chemical Exposure

Multiple Sclerosis

Allergies

Chronic Fatigue

OCD

Alzheimers Disease

Depression

Schizophrenia

Autism

Digestive Disorders

Seizure Disorders

Bipolar Disorder

Eating Disorders

Tourette Syndrome

Candida & Bacteria Overgrowth

Fibromyalgia

Tics disorders and more.

Getting Started with Lab Testing

www.GPL4U.com

customerservice@GPL4U.com

913-341-8949

The value of the GPL4 panel comes from the superior and comprehensive analysis it
provides from a single urine sample and 3 blood tube samples testing for organic acids,
vitamins and mineral levels, food allergies, metal toxicity and Vitamin D. The GPL4 panel
provides an excellent assessment of an individuals metabolism and is targeted to find any
irregularities that are directly related to numerous conditions. Included in the panel are:

Organic Acids Test

Vitamin D

The Organic Acids Test (OAT) provides a metabolic snapshot based on the products the body
discards through the urine. These small, discarded organic acid molecules are byproducts of human
cellular activity, the digestion of foods, and the metabolism of gastrointestinal flora. The Organic
Acids Test includes 74 urinary metabolites, including 9 yeast markers, 8 bacterial markers, 3 oxalate
markers, 3 glycolytic cycle markers, 6 Krebs cycle markers, 7 neurotransmitter markers, 1 folate
metabolism markers, 8 fatty acid oxidation markers, 8 vitamin markers, 3 indicators of detoxification,
14 amino acid metabolites and 1 bone metabolite. This makes it the most comprehensive Organic
Acids test available anywhere.

IgG - Food Allergies Serum


IgG (immunoglobulin G) testing is a useful guide for structuring elimination diets in many chronic
conditions. Individuals with neurological, gastrointestinal, and movement disorders often suffer
from IgG food allergies. IgG Food allergies do not usually release histamine but cause inflamation
and elevated C-reactive protein. The 93 foods tested in the IgG Food Allergy Test w/ Candida can
identify problem foods so they can be eliminated from the patients diet.
Food Intolerance

RBC Metals*
The Red Blood Cell (RBC) Test is an invaluable diagnostic method for assessing insufficiency or
excess of elements that have important functions within cells or on blood cell membranes. Analysis
of red blood cells provides the best diagnostic tool for assessing the status of elements that have
important functions inside cells or on blood cell membranes. Our RBC test provides analysis of 13
essential elements and 5 toxic metals. It is highly recommended for checking levels of deficiency of
minerals and acute exposure to heavy metals.
*The Metals Hair Test is also offered in place of the RBC Metals Test for the Metals Toxicity section in the GPL4 Panel.

Vitamin D
Gastrointestinal Imbalance

Vitamin D is essential for the formation, growth, and repair of bones. Vitamin D is necessary for
normal calcium absorption and immune function. It also improves muscle strength and helps reduce
inflammation. The Vitamin D Test at The Great Plains Laboratory, Inc. measures both D2 and D3 and
can help to determine if sun exposure is adequate, if dietary vitamin D is sufficient, and to assess the
likelihood of malabsorption.

Value for your money:


Please call your GPL representative to inquire about the different billing options available for the GPL4.

Recommended for the following conditions:


AD(H)D
Allergies
Alzheimers Disease
Autism
Bipolar Disorder
Candida & Bacteria Overgrowth

Getting Started with Lab Testing

Chemical Exposure
Chronic Fatigue
Depression
Digestive Disorders
Eating Disorders
Fibromyalgia

Multiple Sclerosis
OCD
Schizophrenia
Seizure Disorders
Tourette Syndrome
Tics disorders and more.

Clinical Lab Test Recommendations

Clinical Lab Test


Recommendations

Clinical Lab Test Recommendations

.com

William Shaw, Ph.D., Director

11813 West 77th Street, Lenexa, KS 66214

(913) 341-8949

Fax (913) 341-6207

www.GPL4U.com

Top Recommended Tests


For Patients with Chronic Illnesses

The Great Plains Laboratory, Inc. (GPL) recommends the following tests for a multitude of
conditions including: bowel disorders, mental health conditions, autoimmune disorders,
autism spectrum disorders, and many other chronic illnesses.

Organic Acids Test (OAT)


GPLs Organic Acids Test (OAT) is the most comprehensive in the market with over 70 markers. It is a snapshot
of the patients metabolism that measures and addresses: yeast and bacteria overgrowth, glutathione and
antioxidant status, vitamin levels and deficiencies, quinolinic acid production (marker for potential brain toxicity
reaction), fatty acid metabolism, in-born errors of metabolism including oxalate and amino acid dysfunction,
neurotransmitters, and Krebs cycle abnormalities.
The OAT, a non-invasive test using a first-morning urine sample, reliably detects the overgrowth of yeast and the
bacterial species Clostridia difficile, which often are not detectable by conventional culture methods. As well as
being markers for microbial growth, abnormally high levels of metabolites from yeast and gastrointestinal bacteria
may be toxic and can contribute to symptoms of many chronic illnesses. GPL is the only lab providing values for
both the Clostridia difficile byproduct 4-Cresol and the marker for other toxic Clostridia species known as HPHPA.
There is also a marker for the beneficial bacteria byproduct DHPPA, which provides a reliable ratio of the bodys
good flora compared to the harmful.
Our OAT is the only lab test with an oxalate section in an organic acids test. Excess oxalates have been implicated
in conditions ranging from kidney stones to fibromyalgia, vulvodynia, and autism. The OAT includes glycolic and
glyceric acids in the oxalate section, which can differentiate between genetic and nutritional components in
disturbed oxalate metabolism.

4- 30
0.88
0.5- 10
4- 20
> 800
273466

Requisition #:

Physician:
Date of Collection:

07/30/2012

Patient Age:

Time of Collection:

08:00 AM

Patient Sex:

Print Date:

08/02/2012

Patient Name:

Metabolic Markers in Urine

Certain uses of the compounds arabinose, citramalic, tartaric, 3-oxoglutaric, carboxycitric,


3,4-dihydroxyphenylpropionic
(DHPPA), and 3-(3-hydroxyphenyl)-3-hydroxypropionic
273466
The Great Plains Laboratory, Inc.
07/30/2012 in our Organic Acids Test and Microbial Organic
(HPHPA) acids in their application to autism
Metabolic Markers in Urine
Reference Range
Patient
Reference Population - Females Under Age 13
Acids Test are protected
by U.S. Patent # 5,686,311, granted Nov. 11, 1997.
Value
Reference Range

Patient
Value

(mmol/mol creatinine)

Reference Population - Females Under Age 13

The Great Plains Laboratory, Inc.

Intestinal Microbial Overgrowth


Yeast and Fungal Markers
1

Citramalic

5-Hydroxymethyl-2-furoic

3-Oxoglutaric

Furan-2,5-dicarboxylic

Furancarbonylglycine

Tartaric

Arabinose

Carboxycitric

Tricarballylic

Requisition #:

Requisition #:

Patient Name:

5.3

3.1

30

7.4

0.52

22

3.1

273466

3.9

0.50

8.6

0.07

11

4-Hydroxyphenylacetic

12

4-Hydroxybenzoic

13

4-Hydroxyhippuric

14

Hippuric

15

3-Indoleacetic

16

Succinic

17

HPHPA (Clostridia Marker)

18

4-Cresol (C. difficile)

19

DHPPA (Beneficial Bacteria)

1.3

0.86

0.08

41

3-Hydroxybutyric

42

Acetoacetic

Malabsorption and Bacterial Markers


2-Hydroxyphenylacetic

34

Indicators
of Detoxification
Patient

Reference Range

1.1

0.45

30

16

43

4-Hydroxybutyric

44

Ethylmalonic

45

27
Methylsuccinic

0.09

2.0

717

11

377

46

Adipic

Suberic

15

48

Sebacic

227

148

76

63

0.73

0.29

6.1
H

Nutritional Markers

4.1

10

59

60

2-Hydroxyisovaleric
3.8

4.315

H
61

4.4
2-Oxoisovaleric

62

5.5
3-Methyl-2-oxovaleric

63

4.1

377

9.7

0.37

0.29

148

64

59

26

1.1

200

101

0.41

Vitamin B5
51

Vitamin B2 (Riboflavin)
52

Glutaric

53

Ascorbic

10

Vitamin Q10 (CoQ10)

01/08/14
54

3-Hydroxy-3-methylglutaric

55

N-Acetylcysteine (NAC)

Biotin (Vitamin H)
56

Methylcitric

5.5

1.2

3.8

0.63

2.4

0.00

5.5

0.00

2.0

0.03

4.4

4.1

39
2-Hydroxyisocaproic

3.2

0.08

2-Oxoisocaproic

0.08

63

1.1

0.70

0.07

0.07

0.54

0.05

0.05

0.03

0.03

0.30

0.28

0.27

2.3

0.51

0.06

1.1

0.59

8.1

2.8

12

0.95

1.6

11

18

6.4

1.7

7 300

2 761

68

70
71

L
73

74

3.0

Page 1 of 9

0.45

Phenylpyruvic
2.7
2.7
Homogentisic
13

13

0.04

4-Hydroxyphenyllactic
N-Acetylaspartic

0.35

0.35

Malonic
0.82
0.82
3-Methylglutaric

0.07

3-Hydroxyglutaric

55

Phosphoric

4.9

0.38

0.38

0.11
L

0.12

1.7

0.11
0.12
0.06
0.59
2.8
1.7
1.6
18

55

3-Methylglutaconic

0.09Metabolites
Bone

76

3.0

Phenyllactic

0.63

Mandelic

75

Glutathione Precursor and Chelating Agent

3.2

2-Oxo-4-methiolbutyric

72

Vitamin C

Top 5 Recommended Tests

66

69

Pantothenic (B5)

1.2

65

Organic Acids Test - Nutritional and Metabolic Profile

52
0.36

0.55

67

Vitamin B6

0.36

2.4

4.6

9.5

52

0.88

1.2

63

2-Hydroxyhippuric

1.2

2.4

3.4

Vitamin B12

Pyridoxic (B6)

7.0

242

Amino
Acid Metabolites
0.55

Testing performed by The Great Plains Laboratory, Inc., Lenexa, Kansas. The Great Plains Laboratory has developed and determined the
6.2
performance characteristics of this test.49
This test Methylmalonic
has not been evaluated
by the U.S. FDA; the FDA does not currently regulate
such testing.

50

Orotic

6.1

39

58

0.45

16

15

47

0.08

2.0

Reference Population - Females Under Age 13

Value
9.0
57
Pyroglutamic

(mmol/mol creatinine)

1.3

(mmol/mol creatinine)
07/30/2012

Date of Collection:

8.6

9.0

Date of Collection:

Physician:

0.50

Metabolic Markers
in Urine
3.6
0.07

Physician:

Patient Name:

7.4

Ketone and
56Fatty
H Acid
242 Oxidation

10

The GPL Organic Acids Test analyzes markers for a number of functional vitamin deficiencies,
including riboflavin, coenzyme Q10, vitamin B12, and biotin. We are the only laboratory with
direct measurement of vitamin C, vitamin B5, and vitamin B6 via urine sample. In addition,
phosphate is an indirect indicator of vitamin D status.

1.7

0.09

1 000 -

4.9

2761

Clinical Lab Test Recommendations

William Shaw, Ph.D., Director

11813 West 77th Street, Lenexa, KS 66214

(913) 341-8949

Fax (913) 341-6207

www.GPL4U.com

IgG Food Allergy Test w/ Candida


GPLs IgG Food Allergy Test identifies sensitivities to 93 foods, including those
commonly eaten as well as several that are used as substitutes for common
trigger foods. IgG antibodies have a much longer half life than the traditional
IgE allergy, and symptoms may occur hours or days after the offending food has
been consumed. Our test also detects IgG antibodies to Candida, a common
yeast species, at no additional charge. Candida overgrowth in the gut may
contribute to food allergies and sensitivities by allowing absorption of partially
digested proteins (peptides), triggering antibody production to foods.
IgG food allergy testing is beneficial for the following conditions: AD(H)D, asthma,
autism, autoimmune and inflammatory disorders, celiac disease, Crohns disease,
diabetes, fatigue, irritable bowel syndrome, migraines, obesity, rheumatoid
arthritis, sleep disorders, and many others.

Date of Collection:
Time of Collection:
Print Date:

est + C. albicans, S. cerevisiae (94)

1.62

High

Egg White

Egg Yolk

Candida Albicans

Milk

Yeast, Bakers *

Yeast, Brewers *

1.92

Whey

Yogurt

Casein

2.50

Cheese

Beef

Goat Cheese

2.01

Lemon

Strawberry

Sorghum

2.16

Moderate

Mozzarella Cheese

2.44

Cranberry

Wheat

4.28

Wheat Gluten

Celery

2.26

Grapefruit

Lettuce

3.92

Garlic

Rye

4.07
2.84
2.37
2.04
2.38
2.17
1.59
2.69
12.84
2.43
3.57
1.98
3.13

Barley

Cocoa

Kidney Bean
Gliadin

Requisition #:
Millet

Patient
Corn Name:
Patient Age:

Low

Sex:

Pinto Bean

Green Bean

Buckwheat

Honey

Chicken

Salmon

Onion

Tomato

Watermelon

Apple

Pear

Pineapple

Pecan

Blueberry

Carrot

Broccoli
Dairy

Banana

Radish

Eggplant

Turkey

Green Pepper

Flax

Cabbage

Cashews

Grape

Pumpkin

3.06
8.40

Lamb

Buckwheat

3.24

Casein

7.15

Corn

3.60

Cheese

7.05

Gliadin

3.95

Goat Cheese

5.91

Millet

3.84

Milk

9.39

Oat

2.11

Mozzarella Cheese

4.65

Rice

1.70

Whey

8.13

Rye

3.88

Yogurt

7.27

Sorghum

5.09

Wheat Gluten

4.34

Wheat

4.72

Legumes - Beans and Peas


Garbanzo Bean

1.96

Green Bean

3.34

Fish

Kidney Bean

4.19

Cod Fish

1.79

Lentil

1.28

Crab

0.99

Lima Bean

1.22

Halibut

1.85

Pea

1.36

Lobster

1.49

Pinto Bean

3.46

Salmon

2.89

Soybean

1.69

Sardine

1.30

Shrimp

0.99

Fruit
Apple

2.60

Apricot

1.81

Meat/Fowl

Banana

2.39

Beef
Chicken

Tuna

1.98
6.39

Blueberry

2.45

Coconut

1.96

Egg White

13.63

Cranberry

4.90

Egg Yolk

12.91

Grape

2.06

Lamb

3.25

3.05

Grapefruit

4.16

Pork

1.68

Lemon

5.40

Turkey

2.26

Orange

2.25

Nuts and Seeds

Papaya

1.78

Almond

1.86

Peach

1.67

Cashews

2.12

Pear

2.60

Flax

2.18

Pineapple

2.59

Hazelnut

1.45

Plum (Prune)

1.69

Peanut

3.77

Strawberry

5.33

Pecan

2.56

Watermelon

2.66

Grains
Barley

Pistachio

2.66

Sesame

2.85

3.61

Mushroom

Date of Collection:

We utilize random split-sample


testing by an independent laboratory to guarantee the accuracy
Time of Collection:
and reliability of our IgG panels.
To
date, all results have corresponded precisely to those obtained
Print Date:
by other, more expensive leading food and environmental
allergy testing facilities.
Requisition #:
Physician Name:

Sesame
Comprehensive
IgG Food Allergy Test + C. albicans, S. cerevisiae (94)
Pistachio

Cane Sugar
Casein
Potato

Cheese

Orange

Goat Cheese

5.91

Millet

9.39

Oat

Mozzarella Cheese

4.65

Rice

Whey

8.13

Rye

Yogurt

7.27

Sorghum

Spinach
Oat

Beet

Patient Name:

Date of Collection:

GPLs IgG Food Allergy Test results are provided inPatient


a semi-quantitative
report which shows
Time of Collection:
Age:
sensitivities in a low, moderate, and high range versus
results from other laboratories that are Print Date:
Sex:
Buckwheat
3.24
shown in a yes / no7.15
report. Our
with food options
Corn results provide rotation diet recommendations
3.60
7.05
Gliadinnew food reactions.
3.95
that patients can use
to prevent
Comprehensive IgG Food Allergy Test + C. albicans, S. cerevisiae

Milk

Wheat Gluten

Garbanzo Bean

1.96

Green Bean

3.34

Fish

Kidney Bean

4.19

Cod Fish

Lentil

1.28

Crab

Lima Bean

1.22

Halibut

Pea

1.36

Lobster

Pinto Bean

3.46

Salmon

Soybean

1.69

Sardine

Fruit

Lenexa, Kansas. The Great Plains Laboratory has developed and determined
Apple
s not been evaluated by the U.S. Food and Drug Administration.

Wheat

Shrimp

Top 5 Recommended Tests


Apricot

2.60
1.81

Meat/Fowl

Banana

2.39

Beef

Blueberry

2.45

Chicken

Coconut

1.96

Egg White

Cranberry

4.90

Egg Yolk

01/08/14

Dairy

At the Great Plains Laboratory, we perform several different methods of quality controls to
ensure the accuracy and reliability of our IgG analysis. We perform a quality control check
using a positive control specimen on each coated micro titer plate lot before we ever put it into
production. By performing the control throughout the lot, we obtain a high level of precision.
To guarantee that there are no false positives reported, we run a no matrix specimen (buffer) on
each batch. Additionally, we incorporate 2 negative controls (no antigen) and 1 positive control
on each individual specimenPhysician
that we
run.
Name:

Legumes - Beans and Peas

8.62

Print Date:

Comprehensive IgG Food Allergy Test + C. albicans, S. cerevisiae (94)

Quality Control

Reactivity Summary

Peanut

Time of Collection:

Sex:

Unlike most other laboratories that test food sensitivities based only on IgG4, GPL offers an affordable measure
of total IgG (IgG1, IgG2, IgG3, and IgG4), providing a more comprehensive and accurate representation of adverse
food-based reactions. IgG4 antibodies do not activate the immune factor termed complement and are incapable of
causing inflammation. Thus, total IgG analysis is far more clinically useful than IgG4 alone.

1.98

2.24

Date of Collection:

Patient Age:

GPL uses an enzyme-linked immunosorbent assay (ELISA) method to measure IgG antibodies in human serum
and dried blood spots (DBS) against offending foods and Candida. The test as a DBS collection is a very easy and
convenient alternative for patients and practitioners who do not have access to a phlebotomist. The specimen can be
collected from the convenience of home and shipped to our laboratory for analysis.

Physician Name:

1.67

Physician Name:

Patient Name:

Testing performed by The Great Plains Laboratory, Inc., Lenexa, Kansas. The Great Plains Laboratory has developed and determined
the performance characteristics of this test. This test has not been evaluated by the U.S. Food and Drug Administration.

Methodology

Requisition #:

Tuna

3.84
2.11

Dairy
Casein
Cheese
Goat Cheese
Milk
Mozzarella Cheese
Whey
Yogurt

1.70
3.88
5.09
4.34
4.72
1.79
0.99

1.85
Legumes - Beans and Peas
1.49
Garbanzo Bean
2.89
Green Bean
Kidney Bean
Lentil
Lima Bean
Pea
Pinto Bean
Soybean

Fruit
Apple

1.30
0.99
1.98
6.39
3.05

13.63
12.91

Buckwheat
7.15

Corn

7.05

Gliadin

5.91

Millet

9.39

Oat

4.65

Rice

8.13

Rye

7.27

Sorghum

1.96

Wheat Gluten
Wheat

3.34

Fish

4.19

Cod Fish

1.28

Crab

1.22

Halibut

1.36

Lobster

3.46

Salmon

1.69

Sardine

2.60

Shrimp
Tuna

.com

IgE Food & Inhalant Allergy Tests


A classic, or Type I, allergy causes immediate reactions to foods/inhalants characterized by
redness, swelling, and heat in the body as a response to elevated blood levels of Immunoglobulin
E (IgE). The symptoms produced by IgE can be subtle and similar to those seen with other
immunoglobulins. GPL offers a serum-based IgE Food Allergy Test that analyzes either 25 (Basic)
or 93 foods (Advanced).
We offer an IgE Inhalant Test that analyzes 36 (Basic) or 69 inhalants (Advanced). The Advanced
IgE Inhalant Test increases the ability of the practitioner to identify numerous offending foods
and/or inhalants, including Thimerosal and Candida which are commonly associated with
neurological, gastrointestinal, and movement disorders.
The use of our IgE Food and Inhalant Allergy Tests can identify sources of allergic reaction to
reduce inflammation, asthma, hives, skin rashes, and other allergic reactions. Elimination of
IgE positive foods and inhalant exposure can bring major improvements in many symptoms or
disorders triggered by common allergens.
Our FDA-approved method of technology maximizes the ability to identify IgE-mediated allergy
response with high specificity and traceability to World Health Organization standards. We perform
several different methods of quality control to ensure the accuracy and reliability of our analysis.

Gluten / Casein Peptides Test


The Great Plains Laboratory is the only lab in the U.S. with an in-house opiate peptides method
that follows federal laboratory regulations. Our peptides test indicates an inability to completely
digest wheat, rye, barley, and milk proteins. Casomorphin is derived from dairy and gliadorphin
is derived from wheat and other gluten-contaminating grains. Individuals who have difficulty
digesting these opiate peptides may experience altered behavior, lack of focus, sleepiness, or
aggression after consumption. Studies show that intolerance to gluten is the cause of multiple
mental disorders, including schizophrenia.
The test indicates sensitivity even when a patient has no IgE- or IgG-mediated response to these
foods, and helps determine whether dietary modifications should be part of an integrated
treatment plan. If either of the peptide results is abnormal, both gluten (from gliadorphin) and
casein (from casomorphin) should be eliminated. Our Gluten/Casein Peptides Test uses the ELISA
method, which is highly specific to the nanogram level (one-billionth of a gram). To accomplish
this, casomorphin and gliadorphin are custom-synthesized to be able to define the very sensitive
standard curve that is required.

Top 5 Recommended Tests

01/08/14

Clinical Lab Test Recommendations

LAB#:
PATIENT:
ID:
SEX:
AGE:

William Shaw, Ph.D., Director

77th Street, Lenexa, KS 66214


11813 West
< 8.0

(913) 341-8949

< 0.080
< 0.020
< 2.0
< 0.15
Heavy metal toxicity, caused by increasing levels of pollution
and the use of
< 1.0
chemicals in industry, is a growing threat to our health
and the development
< 0.40
< 0.005 lead, arsenic, and
of our children. High levels of toxic metals such as mercury,
< 0.010
uranium that are deposited in body tissues and subsequently
in the brain may
< 0.005
< 0.060
cause significant developmental and neurological damage.
< 0.40
< 0.20
< 0.30
The GPL Metals Hair Test is an inexpensive and noninvasive
evaluation of
< 1.0

Fax (913) 341-6207

www.GPL4U.com

Metals Hair Test

LAB#:
PATIENT:
ID:
SEX:
AGE:

< 0.080
< 0.020
< 2.0
< 0.15
< 1.0
< 0.40
< 0.005
< 0.010
< 0.005
< 0.060
< 0.40
< 0.20
< 0.30
< 1.0

39 toxic and essential elements and includes five ratios. The test includes a
total toxic representation, adding weighted factors for each metal. The most
toxic lead, arsenic, cadmium, and mercury
weigh more and increase the

125- 370
representation more.

12- 30
12- 90

As protein is synthesized in the hair follicle, elements12-are40incorporated


permanently into the hair with no further exchange8.0with16other tissues. Scalp
100- 190
0.20- of
0.55one to two cm per
hair is easy to sample, and because it grows an average
0.26- 0.50
month, it contains a temporal record of element metabolism
and exposure
0.030- 0.10
0.050- 0.13
to toxic elements. Synthesis of hair protein concentrates
heavy metals such as
LAB#:
0.60- 4.0
mercuryPATIENT:
to levels 250 times higher than blood.
0.25- 1.3
ID:

< 8.0
< 0.080
< 0.020
< 2.0
< 0.15
< 1.0
< 0.40
< 0.005
< 0.010
< 0.005
< 0.060
< 0.40
< 0.20
< 0.30
< 1.0

125- 370
12- 30
12- 90
12- 40
8.0- 16
100- 190
0.20- 0.55
0.26- 0.50
0.030- 0.10
0.050- 0.13
0.60- 4.0
0.25- 1.3
0.007- 0.023
160- 250
0.95- 1.7
0.16- 1.0
45500- 53000
0.16- 0.80
0.013- 0.035
8.0- 19
0.045- 0.065
0.016- 0.18
0.040- 1.0

4- 30
0.88
0.5- 10
4- 20
> 800

V06.99

0.007- 0.023
160- 250
0.95- 1.7
0.16- 1.0
45500- 53000
0.16- 0.80
0.013- 0.035
8.0- 19
0.045- 0.065
0.016- 0.18
0.040- 1.0

SEX:
AGE:

< 8.0

4- 30
0.88
0.5- 10
4- 20
> 800

V06.99

125- 370
12- 30
12- 90
12- 40
8.0- 16
100- 190
0.20- 0.55
0.26- 0.50
0.030- 0.10
0.050- 0.13
0.60- 4.0
0.25- 1.3
0.007- 0.023
160- 250
0.95- 1.7
0.16- 1.0
45500- 53000
0.16- 0.80
0.013- 0.035
8.0- 19
0.045- 0.065
0.016- 0.18
0.040- 1.0

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About us

The Great Plains Laboratory, Inc. (GPL) is a research-based clinical laboratory offering testing for nutritional
factors in chronic illnesses worldwide. We are dedicated to assisting healthcare practitioners make a difference by
helping children, adults, and families achieve their maximum potential through quality laboratory testing.
We are always happy to hear from our clients and welcome your questions, comments, or suggestions. Were
available to provide consultations for physicians, and help find a medical practitioner in your area.
4- 30
email: customerservice@GPL4U.com
web: www.GPL4U.com phone: (913) 341-8949
0.88
V06.99

0.5- 10
4- 20
> 800

We are providers for Blue Cross Blue Shield, Cigna, Tricare, and United Healthcare.
www.GPL4U.com

Top 5 Recommended Tests


01/08/14

Blue Cross Blue Shield, Cigna, Tricare, and UnitedHealthcare logos are Registered Trademarks of their respective companies. Use of these names and logos
represents the Great Plains Laboratory, Inc.s coverage status with these insurance carriers. The Great Plains Laboratory Inc. is not affiliated with or sponsored
by Blue Cross Blue Shield, Cigna, Tricare, or UnitedHealthcare.

The Clinical Signicance


of the Organic Acids Test
The Organic Acids Test (OAT) provides an accurate metabolic
snapshot of what is going on in the body. Besides offering
the most complete and accurate evaluation of intestinal
yeast and bacteria, it also provides information on important
neurotransmitters, nutritional markers, glutathione status,
oxalate metabolism, and much more. The test includes
74 urinary metabolite markers that can be very useful for
discovering underlying causes of chronic illness.
Patients and physicians report that treating yeast and bacterial
abnormalities reduces fatigue, increases alertness and energy,
improves sleep, normalizes bowel function, and reduces
hyperactivity and abdominal pain.

The Great Plains


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Dont miss our upcoming events, including


one-day Organic Acids Testing workshops!
Visit www.GreatPlainsLaboratory.com
for event dates and locations.
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Organic Acids Test

Clinical Significance of the Organic Acids Test


04/09/15

Page 1

1.2

- Nutritional and

Metabolic Profi
le

Page 2 of 8

William Shaw, Ph.D., Director

11813 West 77th Street, Lenexa, KS 66214

(913) 341-8949

Fax (913) 341-6207

www.GPL4U.com

The following pages list the 74 metabolite markers of the Organic Acids Test. Included is the name of the metabolic marker, its clinical
significance, and usual initial treatment.
INTESTINAL MICROBIAL OVERGROWTH
Yeast and Fungal Markers
Citramalic Acid

Elevated citramalic acid is produced mainly by Saccharomyces species or Propionibacteria overgrowth.


High-potency, multi-strain probiotics may help rebalance GI flora.

5-Hydroxy-methyl-furoic Acid

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription or
natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth levels.

3-Oxoglutaric Acid

Indicates a possible yeast overgrowth in the GI tract. High-potency, multi-strain probiotics may help
rebalance GI flora.

Furan-2,5-dicarboxylic Acid

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription or
natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth levels.

Furancarbonylglycine

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription or
natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth.

Tartaric Acid

Produced by action of Candida hyaluronidase on the intercellular cement, hyaluronic acid. Oxidation of
the hyaluronic acid breakdown by white blood cell hypochlorite produces tartaric acid and arabinose.
Antifungal treatment and high-potency, multi-strain probiotics may help rebalance GI flora.

Arabinose

Produced by action of Candida hyaluronidase on the intercellular cement, hyaluronic acid. Oxidation of
the hyaluronic acid breakdown by white blood cell hypochlorite produces tartaric acid and arabinose.
Antifungal treatment and high-potency, multi-strain probiotics may help rebalance GI flora.

Carboxycitric Acid

Elevated yeast/fungal metabolites indicate overgrowth in the GI tract. Prescription or natural


antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth.

Tricarballylic Acid

A chemical byproduct released from fumonisins during passage through the gastrointestinal tract.
Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused by
the intake of corn or corn-based food contaminated with fumonisins.

Bacterial Markers
Hippuric Acid

A bacterial product of phenylalanine metabolism. Most hippuric acid in urine is derived from microbial
breakdown of chlorogenic acid, a common substance found in beverages and in many fruits and
vegetables. Higher levels indicate GI bacterial overgrowth that can be reduced with natural antibacterial agents and/or high-potency, multi-strain probiotics.

2-Hydroxyphenylacetic Acid

Elevated 2-hydroxyphenylacetic acid is associated with intestinal bacteria overgrowth. High-potency,


multi-strain probiotics may help rebalance GI flora.

4-Hydroxybenzoic Acid

A marker for intestinal dysbiosis. Results may also show elevated values as a result of ingestion of
foods such as jams and pie fillings containing paraben preservatives. The use of probiotics and the
exclusion of paraben-containing foods is the first treatment consideration.

4-Hydroxyhippuric Acid

A glycine conjugate of 4-hydroxybenzoic acid, a metabolite of paraben preservatives. May be elevated


after exposure to paraben antimicrobials in certain foods and cosmetics. Intake of fruits containing
polyphenols rich in anthocyanins, flavonols, and hydroxycinnamates may increase this compound in
the urine. Avoid exposure to parabens.

DHPPA in urine indicates intake of chlorogenic acid, a common substance in beverages and many fruits
and vegetables. Harmless or beneficial bacteria such as Lactobacilli, Bifidobacteria, and E. coli increase
DHPPA
(dihydroxyphenylpropionic acid) the breakdown of chlorogenic acid to DHPPA, so high values are mainly associated with increased
amounts of these species in the GI tract.

Clostridia Bacterial Markers


4-Hydroxyphenylacetic Acid

A tyrosine metabolic product of GI bacteria. Elevated levels are associated with bacterial overgrowth
or small bowel disease. May also indicate celiac disease.

HPHPA (3-(3-hydroxyphenyl)-3hydroxypropionic acid)

An elevated value indicates an overgrowth of certain Clostridia bacteria in the GI tract including
C. sporogenes, C. caloritolerans, and C. botulinum. This metabolite is commonly elevated in autism,
psychiatric disorders, and GI disorders. This metabolite inhibits the enzyme dopamine-betahydroxylase, leading to a derangement of neurotransmitter balance.

4-Cresol

An elevated value indicates an overgrowth in the GI tract of C. difficile. This metabolite is commonly
elevated in autism, psychiatric disorders, and GI disorders. This metabolite inhibits the enzyme,
dopamine-beta-hydroxylase, leading to a derangement of neurotransmitter balance.

3-Indoleacetic Acid

3-Indoleacetic acid is a tryptophan byproduct of the following Clostridia species: C. stricklandii, C.


lituseburense, C. subterminale, and C. putrefaciens. Very high amounts of this metabolite derived from
tryptophan may indicate a depletion of tryptophan needed for other physiological functions.

OXALATE METABOLITES
Glyceric Acid

Elevated in genetic hyperoxaluria type II. Normal values of glyceric acid rule out genetic causes of
significant elevation of oxalic acid in urine.

Glycolic Acid

Very elevated in genetic hyperoxaluria type I. Normal values of glycolic acid rule out genetic causes of
significant elevation of oxalic acid in urine. This genetic disease can be confirmed by DNA testing at the
Mayo Clinic.

Oxalic Acid

Elevated oxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, and possibly
Candida, or from high doses of vitamin C. If yeast or fungal markers are elevated, antifungal therapy
may reduce oxalates. Elevated oxalic acid may also result from anti-freeze (ethylene glycol) poisoning.

GLYCOLYTIC CYCLE METABOLITES

Lactic Acid

Elevated by a number of nonspecific influences, such as vigorous exercise, bacterial overgrowth of the
GI tract, shock, poor perfusion, B-vitamin deficiency, mitochondrial dysfunction or damage, and anemia,
among others. Tiglylglycine is a more specific indicator of mitochondrial dysfunction or damage. The
possibility of an inborn error of metabolism increases when the lactic acid value exceeds 300 mmol/
mol creatinine. There are many inborn errors of metabolism that are present with elevated lactic acid,
including disorders of sugar metabolism, pyruvate dehydrogenase deficiency, and mitochondrial
disorders.

Pyruvic Acid

Elevated by a number of non-specific factors, including vigorous exercise, bacterial overgrowth of


the GI tract, shock, poor perfusion, B-vitamin deficiency, mitochondrial dysfunction or damage, and
anemia, among others. High pyruvic acid indicates the possibility of an inborn error of metabolism
when the value exceeds 100 mmol/mol creatinine.

Clinical Significance of the Organic Acids Test


04/09/15

William Shaw, Ph.D., Director

11813 West 77th Street, Lenexa, KS 66214

(913) 341-8949

Fax (913) 341-6207

www.GPL4U.com

MITOCHONDRIAL MARKERS - KREBS CYCLE METABOLITES


Succinic Acid

An elevated result may indicate a relative deficiency of riboflavin and/or coenzyme Q10. Also
produced by bacterial degradation of unabsorbed glutamine supplement. Low levels may indicate
the need for leucine/isoleucine supplementation. Suggest supplementation with riboflavin and/or
coenzyme Q10.

Fumaric Acid

Increased urinary fumaric acid may be due to impaired Krebs cycle function, a defect in the enzyme
fumarase, or in mitochondrial function. To support mitochondrial function, supplement with
coenzyme Q10, nicotinamide adenine dinucleotide (NAD+), L-carnitine and acetyl-L-carnitine,
riboflavin, nicotinamide, biotin, and vitamin E.

Malic Acid

Slightly elevated values usually indicate a higher need for nutrients such as niacin and coenzyme
Q10. When malic acid is simultaneously elevated with citric, fumaric, and 2-ketoglutaric acids, a
mitochondrial energy pathway dysfunction is strongly suggested.

2-Oxoglutaric Acid

Increased values in urine may be due to dietary vitamin deficiencies or the intake of 2-ketoglutaric acid
as a supplement. The conversion of 2-oxoglutaric acid to succinyl-CoA requires coenzyme A (derived
from pantothenic acid), flavin adenine dinucleotide (FAD) derived from riboflavin, and thiamine.

Aconitic Acid

Aconitase, the enzyme that metabolizes citric and aconitic acids, is dependent upon glutathione.
Elevated in mitochondrial disorders (e.g. Complex I and Pierson Syndrome). Elevated aconitic acid may
indicate an additional requirement for reduced glutathione.

Citric Acid

Elevations may be due to increased intake of citric acid-containing foods or result from intestinal
yeast-producing citric acid, or perhaps inhibiting the human citric acid cycle. Increased citric acid
may also indicate depletion of glutathione, which is required for the enzyme, aconitase to metabolize
both aconitic and citric acids. If pyroglutamic acid values are low, consider supplements containing
glutathione, or n-acetyl-cysteine.

MITOCHONDRIAL MARKERS - AMINO ACID METABOLITES


3-Methylglutaric Acid
3-Methylglutaconic

Significant increase is due to a reduced ability to metabolize the amino acid, leucine. This abnormality
is found in the genetic disease, methylglutaconic aciduria and in mitochondrial disorders.
3-Methylglutaconic acid may also be elevated. Supplementation with coenzyme Q10, niacin,
L-carnitine and acetyl-L-carnitine, riboflavin, nicotinamide, biotin, and vitamin E may be useful.

3-Hydroxyglutaric

Marker of glutaryl CoA dehydrogenase deficiency. This enzyme is involved in the breakdown of
lysine, hydroxylysine, and tryptophan, and is associated with the genetic disease, glutaric aciduria
type 1. Elevated 3-hydroxyglutaric acid may occur in combination with glutaric and glutaconic acids.
Symptoms of glutaryl CoA dehydrogenase deficiency are varied. Some individuals appear normal,
while others display encephalopathy, autism, cerebral palsy, and additional neurological abnormalities.
Treatment includes adherence to a diet low in lysine and supplementation with carnitine.

NEUROTRANSMITTER METABOLISM
Phenylalanine and Tyrosine Metabolites
HVA and VMA

HVA (homovanillic acid), a dopamine metabolite, and VMA (vanillylmandelic acid), a metabolite of
epinephrine and norepinephrine, are often elevated due to stress increasing catecholamine output
from the adrenal gland, or from lead toxicity. Elevated HVA may also result from the intake of L DOPA,
dopamine, phenylalanine, or tyrosine, or due to Clostridia metabolites.

HVA/VMA Ratio

An elevated ratio is often the result of a decreased conversion of dopamine to norepinephrine by the
enzyme, dopamine beta-hydroxylase. Inhibition of this enzyme is commonly caused by Clostridia byproducts, including HPHPA, 4-cresol, and 4-hydroxyphenylacetic acid.
Continued on the next page

Tryptophan Metabolites

5-Hydroxyindoleacetic Acid

Metabolite of the neurotransmitter, serotonin. Elevated values may result from supplementing
tryptophan or 5 hydroxy tryptophan (5-HTP). Low values may indicate inadequate production of the
neurotransmitter, serotonin. Often slightly elevated by ingestion of foods high in serotonin, such as
avocado, banana, tomato, plum, walnut, pineapple, or eggplant. High values are found in carcinoid
syndrome.

Quinolinic Acid

Increased values in urine may be caused by various factors such as chronic inflammation from
microbial infections, central nervous system degeneration, excessive tryptophan supplementation,
or even exposure to phthalates. Reduce excess quinolinic acid by eliminating tryptophan
supplementation and also reduce exposure to infections and environmental pollutants. Brain damage
induced by quinolinic acid can be mitigated by supplements containing acetyl L-carnitine, melatonin,
B6, turmeric, and garlic.

Kynurenic Acid (KYNA)

The most common causes of elevated kynurenic acid are the use of tryptophan supplements and
the presence of chronic infections. Very high urine values are found in genetic disorders involving
kynureninase deficiency.

Quinolinic Acid / 5-HIAA Ratio

A high ratio indicates excessive inflammation due to recurrent infections, excessive tryptophan intake,
immune overstimulation, excessive adrenal production of cortisol, or excessive exposure to phthalates.

PYRIMIDINE METABOLITES - FOLATE METABOLISM


Uracil

Because folic acid is involved as a methyl donor in the conversion of uracil to thymine, elevated uracil
may indicate a defect in folic acid metabolism. Elevated uracil is found in about 10% of children with
autism.

Thymine

Slightly elevated urinary thymine has no clinical significance. High values are associated with
inflammatory diseases and cancer. Elevated pyrimidines and elevated thymine have been reported in
dihydropyrimidine dehydrogenase deficiency, a rare genetic disease, which has been associated with
seizures and autism.

KETONE AND FATTY ACID OXIDATION


3-Hydroxybutyric Acid
Acetoacetic Acid

Ketones, such as 3-hydroxybutyric and acetoacetic acids, are the end-products of rapid or excessive
fatty acid breakdown. Common causes of elevated ketones are prolonged fasting, protein malnutrition,
high fat diet, vitamin B12 deficiency, severe GI Candida overgrowth, and pulmonary infections.

4-Hydroxybutyric Acid

A moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplements
containing 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may
indicate the genetic disorder involving succinic semialdehyde dehydrogenase deficiency.

Adipic Acid

Slightly elevated adipic acid may result from excessive ingestion of gelatin or other junk food
containing adipic acid as an additive. Elevated adipic acid may also indicate an abnormality in fatty
acid metabolism. Dietary supplements containing L-carnitine or L-acetyl-carnitine may be beneficial.

Suberic Acid
Sebacic Acid
Ethylmalonic Acid
Methylsuccinic Acid

Increased urinary products of the omega fatty acid metabolism pathway may be due to carnitine
deficiency, fasting, or increased intake of triglycerides from coconut oil, or some infant formulas. Very
elevated values may indicate a genetic disorder. Fatty acid oxidation defects are associated with
hypoglycemia and lethargy. Regardless of cause, intake of dietary supplements containing L-carnitine
or acetyl-L-carnitine may improve clinical symptoms.

Clinical Significance of the Organic Acids Test


04/09/15

William Shaw, Ph.D., Director

11813 West 77th Street, Lenexa, KS 66214

(913) 341-8949

Fax (913) 341-6207

www.GPL4U.com

NUTRITIONAL MARKERS
Methylmalonic Acid
(Vitamin B12)

Slightly elevated methylmalonic acid is commonly associated with vitamin B12 deficiency, or other
factors such as pernicious anemia, GI bacterial metabolism, malabsorption, or gastroenteritis in very
young infants. Very elevated values may indicate a genetic disorder.

Pyridoxic Acid
(Vitamin B6)

A major metabolite of vitamin B6. High pyridoxic acid indicates high recent intake of vitamin B6.
Because some individuals may require very high doses of vitamin B6, high values do not necessarily
indicate the need to reduce vitamin B6 intake. Low values are associated with low B6 status, high
oxalates, and/or low neurotransmitters.

Pantothenic Acid
(Vitamin B5)

An essential vitamin (vitamin B5). High pantothenic acid indicates high recent intake of pantothenic
acid. Since some individuals may require very high doses of pantothenic acid, high values do not
necessarily indicate the need to reduce pantothenic acid intake.

Glutaric Acid
(Vitamin B2)

Elevation indicates riboflavin deficiency (vitamin B2), a common factor in moderate urinary increases
of glutaric acid. Other possible factors include fatty acid oxidation defects and metabolic effects of
valproic acid (Depakene), or celiac disease. The probability of a genetic disease is higher with very high
values. The use of dietary supplements containing riboflavin and coenzyme Q10 may improve clinical
symptoms. This compound may be elevated in about 10% of children with autism.

Ascorbic Acid
(Vitamin C)

Commonly elevated by supplementation. High values are usually of no concern, except in individuals
with extremely high intake (>2000 mg/day), in whom ascorbic acid may be converted to oxalic acid,
increasing the risk of kidney stones. It is unlikely that elevated vitamin C will contribute to kidney
stone formation if oxalic acid is in the normal range.

The precursor of coenzyme Q10 and cholesterol. Slightly increased values may be caused by
3-Hydroxy-3-methylglutaric Acid gastrointestinal yeast overgrowth. A moderate increase in urine HMG may also indicate decreased
(Coenzyme Q10)
synthesis of coenzyme Q10. Certain cholesterol-lowering drugs may inhibit the synthesis pathway and
result in high HMG values. Very elevated values may be caused by the genetic disorder, HMG aciduria.
N-Acetylcysteine Acid

A powerful antioxidant that increases the glutathione reserves in the body. Together with glutathione,
acetylcysteine directly binds to toxic metabolites. Although acetylcysteine may be beneficial under
certain conditions, excessive use of the supplement could be harmful.

Methylcitric Acid
(Biotin (Vitamin H)

Elevation usually indicates a biotin deficiency (Vitamin H). Biotin deficiency may be due to
malabsorption, excessive intake of raw egg white, dietary deficiency, or dysbiosis. Higher levels may
indicate the presence of genetic disorders involving biotin-dependent enzymes and may require biotin
supplementation at very high doses.

INDICATORS OF DETOXIFICATION
Glutathione

Pyroglutamic Acid

Pyroglutamic acid is a metabolite of glutathione. Glutathione serves as an antioxidant and is also


conjugated to toxic compounds in the liver. Elevated values are most commonly caused by glutathione
deficiency due to toxic exposure, such as acetaminophen toxicity. Elevated pyroglutamic acid may
also result from a genetic disorder, metabolic effects of certain antibiotics, or intake of certain infant
formulas. Supplementation with liposomal glutathione or N-acetyl-cysteine can raise glutathione
levels. Selenium is essential to the antioxidant activity of glutathione; usually, adequate selenium can
be obtained from a quality multivitamin.

2-Hydroxybutyric Acid

Elevated 2-hydroxybutyric acid is a byproduct of the breakdown of the sulfur amino acid metabolite,
cystathionine, which may be formed in excess during oxidative stress or when toxic exposures increase
the need for detoxification. When glutathione is depleted by excessive toxic exposure, pyroglutamic
acid may also be elevated. High values of 2-hydroxybutyric acid may also be associated with the onset
of diabetes mellitus or significant alcohol intake. This compound may also be elevated in certain
genetic diseases such as lactic acidosis, glutaric aciduria type II, dihydrolipoyl dehydrogenase (E3)
deficiency, and propionic aciduria.
Continued on the next page

Ammonia Excess
Orotic Acid

Elevations are most commonly associated with ammonia toxicity. Elevated ammonia may result from
drug toxicity to the liver, viral liver infection, gastrointestinal bleeding, or inborn errors of ammonia
metabolism. Confirmation of a genetic disorder requires testing plasma amino acids.

Aspartame, Salicylates, or GI bacteria


2-Hydroxyhippuric Acid

A conjugate of the amino acids, glycine and hydroxybenzoic acid (salicylic acid). Intake of aspirin
(salicylates) or the growth of salicylate-producing gastrointestinal bacteria may elevate levels. Also
increased after the ingestion of the artificial sweetener, aspartame (Nutrasweet).

AMINO ACID METABOLITES


2-Hydroxyisovaleric Acid
2-Oxoisovaleric Acid
3-Methyl-2-oxovaleric Acid
2-Hydroxyisocaproic Acid
2-Oxoisocaproic Acid

A moderate increase of branched-chain amino acid metabolites in urine may result from lactic acidosis,
episodic ketosis, or deficiencies of the vitamins, thiamine or lipoic acid. Elevated 2-hydroxyisocaproic
acid in urine has also been linked to short bowel syndrome. A significant increase of branched-chain
amino acid metabolites is associated with the genetic disorders, maple syrup urine disease (MSUD)
and pyruvate dehydrogenase deficiency. Patients with slight to moderate elevations may use dietary
supplements containing thiamine to improve clinical symptoms.

2-Oxo-4-methiolbutyric Acid

Elevated in an inborn error of methionine metabolism. Confirmation of the genetic disorder requires
testing of plasma amino acids.

Mandelic Acid

Increased by dietary phenylalanine or phenylalanine supplementation, but also due to exposure


to styrene, a toxic environmental compound. Significant elevation is found in the genetic disorder,
phenylketonuria (PKU). A plasma phenylalanine test will rule out PKU.

Phenyllactic Acid

A metabolite of phenylalanine. Elevated values indicate increased intake of dietary phenylalanine or


the heterozygous carrier status (homozygosity) for the genetic disease, phenylketonuria (PKU). Values
observed in clinically diagnosed PKU typically exceed 200 mmol/mol creatinine.

Phenylpyruvic Acid

Moderate elevations may result from intake of phenylalanine, from genetic carrier status for PKU, or
from a deficiency in production of biopterin, a cofactor required for phenylalanine metabolism. Very
high values are associated with the genetic disease, PKU.

Homogentisic Acid

Homogentisic acid is elevated in the genetic disorder, homogentisic aciduria (alkaptonuria). Slight
increases may indicate the heterozygous genetic carrier state of the disease.

4-Hydroxyphenyllactic Acid

Increased values are commonly associated with tyrosinemias, which can result from immature
development of enzyme synthesis in infants or genetic deficiencies. Slight increases may be due to
increased tyrosine intake, bacterial gut metabolism, short bowel syndrome, or liver disease.

N-Acetylaspartic Acid

Elevated N-acetylaspartic acid is due to the genetic disorder, Carnavans disease, a potentially fatal
disease causing spongy degeneration of the brain.

Malonic Acid

Associated with the genetic disorders, malonyl-CoA decarboxylase deficiency and malonic aciduria
with normal malonyl-CoA decarboxylase activity. Slightly elevated values in urine are unlikely to be
clinically significant.

MINERAL METABOLITES

Phosphoric Acid

Phosphate urinary excretion is directly proportional to dietary intake. Processed foods high in
phosphate include: sodas, candy, ice cream, chocolate, mayonnaise, frozen pizza, commercially baked
goods, and meats. Excess phosphate is also associated with hyperparathyroidism, vitamin D-resistant
rickets, immobilization following paraplegia or fracture due to bone resorption, vitamin D intoxication,
blood lead levels above 1.5 ppm, renal tubular damage, familial hypophosphatemia, and metabolic
acidosis. Low urinary phosphate is most common in low phosphate intake and in vitamin D deficiency.

Clinical Significance of the Organic Acids Test


04/09/15

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Page 1 of 8
Organic Acids Test - Nutritional and Metabolic Profile

thi

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Glu
58

Test & Pricing Information

Test & Pricing


Information

Test & Pricing Information

Physician Price List


Nutritional, Environmental, and Metabolic Assessments
Organic Acids Test (OAT) (74) Urine
Microbial Organic Acids Test (MOAT) (21) Urine

Physician Billing
Price*

Patient Cash
Price**

List Price***

Out-of-Network Down
Payment****

$239
$159

$299
$199

$599
$449

$120
$90

$135

$27

Advanced Cholesterol Profile Serum

$85

$110

Amino Acids Test - Plasma or Urine (24 hr. or Random) (43)

$199

$229

Insurance Not Available

C-Reactive Protein Test (hs-CRP) Serum

$55

$70

$85

Ceruloplasmin Test Serum

$60

$85

$95

$19

Comprehensive Fatty Acids Test Serum

$209

$239

$299

$60

(when ordered with the OAT/MOAT)

$199 ($149)

$219 ($169)

Insurance Not Available

$129

$129

Insurance Not Available

(when ordered with the OAT/MOAT)

$99 ($39)

$99 ($39)

$55

$70

$85

$17

$65 ($29)

$65 ($29)

$85 ($39)

$17 ($8)

$48

$58

$99

$20

Physician Billing
Price*

Patient Cash
Price**

List Price***

Out-of-Network Down
Payment****

GPL-TOX (Toxic Organic Chemical Profile)


Kryptopyrrole Test Urine
Phospholipase A2 Activity Test (PLA2)
Prealbumin Test Serum
Uric Acid Test (24 hr. or Random) Urine

(when ordered with the OAT/MOAT)

Vitamin D Test Serum or Dried Blood Spot (DBS)


DNA Methylation Pathway
DNA Methylation Pathway Profile Dried Blood Spot (DBS)
Stool Tests
Comprehensive Stool Analysis with Parasitology
Yeast Culture w/ Sensitivity Test
Hormone Tests
Hormones Comprehensive Panel
Hormones Comprehensive Plus Panel
Hormones Short Comprehensive Panel

$17

Insurance Not Available

$429

$459

Physician Billing
Price*

Patient Cash
Price**

Insurance Not Available


List Price***

Out-of-Network Down
Payment****

$295
$140

$345
$170

$599
$225

$92
$45

Physician Billing
Price*

Patient Cash
Price**

List Price***

Out-of-Network Down
Payment****

$215
$225

$225
$275

$255
$325

$51
$65

$195

$215

$225

$45

Physician Billing
Price*

Patient Cash
Price**

List Price***

Out-of-Network Down
Payment****

IgG Food Allergy Test w/ Candida (94) Serum or Dried Blood Spot (DBS)
IgG Asian Food Allergy Test w/ Candida (94) Serum or Dried Blood Spot (DBS)

$165
$165

$219
$219

$325
$325

$65
$65

Celiac Disease Test Serum

$85

$109

$165

$33

Gluten / Casein Peptides Test Urine

$85

$110

$119

$24

IgE Allergy Advanced Combined Test (93 / 69) Serum

$700

$729

$800

$160

Food Allergies, Sensitivities, and Immune System

IgE Food Allergy Essentials Test (12) Serum

$75

$75

$119

$24

IgE Food Allergy Basic Test (25) Serum


IgE Food Allergy Advanced Test (93) Serum

$219
$449

$270
$479

$379
$579

$76
$116

IgE Inhalant Allergy Basic Test (36) Serum


IgE Inhalant Allergy Advanced Test (69) Serum

$219
$349

$270
$379

$379
$449

$76
$90

Immune Deficiency Profile Serum


Streptococcus Antibodies Profile Serum

$179
$55

$239
$70

$299
$85

$60
$17

Physician Billing
Price*

Patient Cash
Price**

List Price***

Out-of-Network Down
Payment****

Metals Hair Test (39)


Copper Test Serum

$115
$35

$140
$35

$250
$60

$50
$12

Copper / Zinc Profile Serum

$135

$165

$215

$43

Metals Fecal Test (13)

$115

$140

$250

$50

Metals Red Blood Cell Test (18)

$235

$285

$360

$72

Metals Urine (24 hr., Timed or Random) Test (37)

$165

$185

$299

$60

Metals Whole Blood Test (20)

$180

$210

$320

$64

Porphyrins Profile Urine

$85

$109

$145

$29

Zinc Test Serum

$35

$35

$60

$12

Metals and Essential Elements

Physician Billing
Price*

Patient Cash
Price**

List Price***

Out-of-Network Down
Payment****

OAT + Amino Acids Urine Test Combo Urine


OAT + IgG Food Allergy Test w/ Candida Combo Urine & Serum or Dried Blood Spot
(DBS)
OAT + Yeast Culture w/ Sensitivity Test Combo Urine & Stool

$425

$515

$899

$180

$399

$499

$699

$140

$319

$399

$699

$140

MOAT + Yeast Culture w/ Sensitivity Test Combo Urine & Stool

$239

$299

$549

$110

GPL3: Organic Acids Test + Metals Hair + IgG Dried Blood Spot (DBS)

$514

$559

$949

$190

$562

$599

$1048

$210

$682

$699

$1,158

$232

$279

$444

$89

Combo Tests

GPL4-DBS: Organic Acids Test + IgG Food Allergy Test + Metals Hair + Phospholipase A2
Activity Test
GPL4-Serum: Organic Acids Test + IgG Food Allergy Test + Red Blood Cell +
Phospholipase A2 Activity Test
IgG Food Allergy Test w/ Candida + IgE Food Allergy Essentials Test Serum

Test Panels

$225
Physician Billing Price*

Patient Cash
Price**

List Price***

Out-of-Network Down
Payment****

$1,495

$1,835

$2,599

$492

$894

$1,094

$1,667

$305

$1,716

$2,070

$3,124

$597

$808

$988

$1,367

$273

$1,686

$2,070

$3,124

$597

$753

$918

$1,268

$254

$1,188

$1,457

$2,376

$447

$599

$749

$1,068

$214

$1,366

$1,655

$2,440

$488

$723

$878

$1,248

$250

$1,570

$1,895

$2,714

$515

$1,007

$1,217

$1,666

$333

Comprehensive Autism Panel


Advanced Cholesterol Profile
Comprehensive Stool Analysis
Copper / Zinc Profile
Ferritin Test

Gluten / Casein Peptides Test


IgG Food Allergy Test w/ Candida
Immune Deficiency Profile
Metals Hair Test

Organic Acids Test


Streptococcus Antibodies Profile
Vitamin D Test

IgG Food Allergy Test w/ Candida


Metals Hair Test

Organic Acids Test

Basic Autism Panel


Comprehensive Stool Analysis
Gluten / Casein Peptides Test

Comprehensive AD(H)D Panel


Advanced Cholesterol Profile
Amino Acids Urine Test
Comprehensive Fatty Acids Test
Comprehensive Stool Analysis

Copper / Zinc Profile


Ferritin Test
Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida

Metals Hair Test


Organic Acids Test
Streptococcus Antibodies Profile
Vitamin D Test

IgG Food Allergy Test w/ Candida


Metals Hair Test

Organic Acids Test

Basic AD(H)D Panel


Comprehensive Fatty Acids Test
Gluten / Casein Peptides Test

Comprehensive Tourettes & Tics Panel


Advanced Cholesterol Profile
Amino Acids Urine Test
Comprehensive Stool Analysis
Copper / Zinc Profile

Ferritin Test
Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida
Immune Deficiency Profile

Metals Hair Test


Organic Acids Test
Streptococcus Antibodies Profile
Vitamin D Test

Basic Tourettes & Tics Panel


Advanced Cholesterol Profile
Ferritin Test

IgG Food Allergy Test w/ Candida


Metals Hair Test

Organic Acids Test


Streptococcus Antibodies Profile

Comprehensive Fibromyalgia & CFS Panel


Amino Acids Urine Test
C-Reactive Protein Test
Comprehensive Stool Analysis

Gluten / Casein Peptides Test


IgG Food Allergy Test w/ Candida
Metals Hair Test

Organic Acids Test


Vitamin D Test

Basic Fibromyalgia & CFS Panel


Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida

Metals Hair Test


Organic Acids Test

Comprehensive Wellness Panel


Advanced Cholesterol Profile
Amino Acids Urine Test
Comprehensive Fatty Acids Test
Copper / Zinc Profile

Ferritin Test
Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida
Metals Hair Test

Organic Acids Test


Vitamin D Test

Basic Wellness Panel


Comprehensive Fatty Acids Test
IgG Food Allergy Test w/ Candida

Metals Hair Test


Organic Acids Test

Comprehensive Mental Health Panel


Advanced Cholesterol Profile
Amino Acids Plasma Test
Comprehensive Fatty Acids Test
Comprehensive Stool Analysis

Copper / Zinc Profile


Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida
Metals Hair Test

Organic Acids Test


Vitamin D Test

Basic Mental Health Panel


Amino Acids Plasma Test
Comprehensive Fatty Acids Test

Gluten / Casein Peptides Test


IgG Food Allergy Test w/ Candida

Metals Hair Test


Organic Acids Test

* Physician billing is unavailable in New Jersey and Rhode Island.


** Payment must be submitted with sample. We accept checks, money orders, wire transfers, and all major credit cards.
*** Price commonly billed to insurance. See insurance section on website or Test Requisition Form for exceptions.
**** Out-of-network down payment (approx. 20% of list price) due upon submission (no up-front payment for in-network billing: some BCBS, Tricare, and Medicare).
All prices are subject to change without prior notice.

Revised 07/10/15

Patient Price List


Nutritional, Environmental, and Metabolic Assessments
Organic Acids Test (OAT) (74) Urine

Cash Price*

List Price**

Out-of-Network Down
Payment***

$299

$599

$120

Microbial Organic Acids Test (MOAT) (21) Urine

$199

$449

$90

Advanced Cholesterol Profile Serum

$110

$135

$27

Amino Acids Test Plasma or Urine (24 hr. or Random) (43)

$229

C-Reactive Protein Test (hs-CRP) Serum

$70

Insurance Not Available

$85

$17

Ceruloplasmin Test Serum

$85

$95

$19

Comprehensive Fatty Acids Test Serum

$239

$299

$60

GPL-TOX (Toxic Organic Chemical Profile)

(when ordered with the OAT/MOAT)

$219 ($169)

Insurance Not Available

$129

Insurance Not Available

(when ordered with the OAT/MOAT)

$99 ($39)

Prealbumin Test Serum


Uric Acid Test (24 hr. or Random) Urine
(when ordered with the OAT/MOAT)
Vitamin D Test Serum or Dried Blood Spot (DBS)

$70
$65 ($29)
$58

$85
$85 ($39)
$99

$17
$17 ($8)
$20

DNA Methylation Pathway

Cash Price*

List Price**

Out-of-Network Down
Payment***

Kryptopyrrole Test Urine


Phospholipase A2 Activity Test (PLA2)

DNA Methylation Pathway Profile Dried Blood Spot (DBS)

$459

Insurance Not Available

Insurance Not Available

Cash Price*

List Price**

Out-of-Network Down
Payment***

Comprehensive Stool Analysis with Parasitology

$345

$599

$92

Yeast Culture w/ Sensitivity Test

$170

$225

$45

Cash Price*

List Price**

Out-of-Network Down
Payment***

$225

$255

$51

Stool Tests

Hormones Tests
Hormones Comprehensive Panel
Hormones Comprehensive Plus Panel

$275

$325

$65

Hormones Short Comprehensive Panel

$215

$225

$45

Cash Price*

List Price**

Out-of-Network Down
Payment***

IgG Food Allergy Test w/ Candida (94) Serum or Dried Blood Spot (DBS)

$219

$325

$65

IgG Asian Food Allergy Test w/ Candida (94) Serum or Dried Blood Spot (DBS)

$219

$325

$65

Celiac Disease Test Serum

$109

$165

$33

Gluten / Casein Peptides Test Urine

$110

$119

$24

IgE Allergy Advanced Combined Test (93 / 69) Serum

$729

$800

$160

IgE Food Allergy Essentials Test (12) Serum

$75

$119

$24

Food Allergies, Sensitivities, and Immune System

IgE Food Allergy Basic Test (25) Serum

$270

$379

$76

IgE Food Allergy Advanced Test (93) Serum

$479

$579

$116

IgE Inhalant Allergy Basic Test (36) Serum

$270

$379

$76

IgE Inhalant Allergy Advanced Test (69) Serum

$379

$449

$90

Immune Deficiency Profile Serum

$239

$299

$60

Streptococcus Antibodies Profile Serum

$70

$85

$17

Cash Price*

List Price**

Out-of-Network Down
Payment***

Metals Hair Test (39)

$140

$250

$50

Copper Test Serum

$35

$60

$12

Copper / Zinc Profile Serum

$165

$215

$43

Metals Fecal Test (13)

$140

$250

$50

Metals Red Blood Cell Test (18)

$285

$360

$72

Metals Urine (24 hr., Timed or Random) Test (37)

$185

$299

$60

Metals Whole Blood Test (20)

$210

$320

$64

Porphyrins Profile Urine

$109

$145

$29

Zinc Test Serum

$35

$60

$12

Metals and Essential Elements

Cash Price*

List Price**

Out-of-Network Down Payment***

OAT + Amino Acids Urine Test Combo Urine

$515

$899

$180

OAT + IgG Food Allergy Test w/ Candida Combo - Urine & Serum or Dried Blood Spot (DBS)

$499

$699

$140

OAT + Yeast Culture w/ Sensitivity Test Combo Urine & Stool

$399

$699

$140

MOAT + Yeast Culture w/ Sensitivity Test Combo Urine & Stool

$299

$549

$110

GPL3: Organic Acids Test + Metals Hair + IgG Dried Blood Spot (DBS)

$559

$949

$190

GPL4-DBS: Organic Acids Test + IgG Food Allergy Test + Metals Hair + Phospholipase A2 Activity Test

$599

$1048

$210

GPL4-Serum: Organic Acids Test + IgG Food Allergy Test + Red Blood Cell + Phospholipase A2
Activity Test

$699

$1,158

$232

IgG Food Allergy Test w/ Candida + IgE Food Allergy Essentials Test Serum

$279

$444

$89

Cash Price*

List Price**

Out-of-Network Down Payment***

Combo Tests

Test Panels
Comprehensive Autism Panel:
Advanced Cholesterol Profile
Comprehensive Stool Analysis
Copper / Zinc Profile
Ferritin Test

Gluten / Casein Peptides Test


IgG Food Allergy Test w/ Candida
Immune Deficiency Profile
Metals Hair Test

Organic Acids Test


Streptococcus Antibodies Profile
Vitamin D Test

$1,835

$2,599

$492

Metals Hair Test


IgG Food Allergy Test w/ Candida

Organic Acids Test

$1,094

$1,667

$305

$2,070

$3,124

$597

$988

$1,367

$273

$2,070

$3,124

$597

$918

$1,268

$254

$1,457

$2,376

$447

$749

$1,068

$214

$1,655

$2,440

$488

$878

$1,248

$250

$1,895

$2,714

$515

$1,217

$1,666

$333

Basic Autism Panel


Comprehensive Stool Analysis
Gluten / Casein Peptides Test

Comprehensive AD(H)D Panel


Advanced Cholesterol Profile
Amino Acids Urine Test
Comprehensive Fatty Acids Test
Comprehensive Stool Analysis

Copper / Zinc Profile


Ferritin Test
Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida

Metals Hair Test


Organic Acids Test
Streptococcus Antibodies Profile
Vitamin D Test

Metals Hair Test


Organic Acids Test

IgG Food Allergy Test w/ Candida

Basic AD(H)D Panel


Comprehensive Fatty Acids Test
Gluten / Casein Peptides Test

Comprehensive Tourettes & Tics Panel


Advanced Cholesterol Profile
Amino Acids Urine Test
Comprehensive Stool Analysis
Copper / Zinc Profile

Ferritin Test
Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida
Immune Deficiency Profile

Organic Acids Test


Streptococcus Antibodies Profile
Vitamin D Test
Metals Hair Test

Basic Tourettes & Tics Panel


Advanced Cholesterol Profile
Ferritin Test

Metals Hair Test


Organic Acids Test

IgG Food Allergy Test w/ Candida


Streptococcus Antibodies Profile

Comprehensive Fibromyalgia & CFS Panel


Amino Acids Urine Test
C-Reactive Protein Test
Comprehensive Stool Analysis

IgG Food Allergy Test w/ Candida


Metals Hair Test
Organic Acids Test

Gluten / Casein Peptides Test


Vitamin D Test

Basic Fibromyalgia & CFS Panel


Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida

Metals Hair Test


Organic Acids Test

Comprehensive Wellness Panel


Advanced Cholesterol Profile
Amino Acids Urine Test
Comprehensive Fatty Acids Test
Copper / Zinc Profile

Ferritin Test
Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida

Metals Hair Test


Organic Acids Test
Vitamin D Test

Basic Wellness Panel


Comprehensive Fatty Acids Test
IgG Food Allergy Test w/ Candida

Metals Hair Test


Organic Acids Test

Comprehensive Mental Health Panel


Advanced Cholesterol Profile
Amino Acids Plasma Test
Comprehensive Fatty Acids Test
Comprehensive Stool Analysis

Copper / Zinc Profile


Gluten / Casein Peptides Test
IgG Food Allergy Test w/ Candida

Metals Hair Test


Organic Acids Test
Vitamin D Test

Basic Mental Health Panel


Amino Acids Plasma Test
Comprehensive Fatty Acids Test

IgG Food Allergy Test w/ Candida


Metals Hair Test

Gluten / Casein Peptides Test


Organic Acids Test

All prices are subject to change without prior notice.


* Payment must be submitted with sample. We accept checks, money orders, wire transfers, and all major credit cards.
** Price commonly billed to insurance. Some BCBS plans are not considered in-network, see insurance section on website or Test Requisition Form for exceptions.
*** Out-of-network down payment (approx. 20% of list price) due upon submission (no up-front payment for in-network billing: some BCBS, Tricare, and Medicare).

Revised 07/10/15

Test / Turn Around Time


Advanced Cholesterol Profile
2 - 4 weeks

Amino Acids Urine Test (43)


Amino Acids Plasma Test (43)
2 - 4 weeks

C-Reactive Protein Test (hs-CRP)


1 - 3 weeks

Description
Total cholesterol, Apolipoprotein A-1 (Apo A-1), Apolipoprotein B (Apo B), Lipoprotein (a) (Lp (a)), Homocysteine
Alanine, Beta-Alanine, Alpha-Aminoadipic, Alpha-Aminobutyric, Gamma-Aminobutyric, Beta-Aminoisobutyric, Ammonia, Anserine, Arginine, Asparagine, Aspartic,
Carnosine, Citrulline, Cystathionine, Cysteine, Cystine, Ethanolamine, Glycine, Glutamic, Glutamine, Histidine, Homocysteine, Hydroxyproline, Isoleucine,
Leucine, Lysine, Met Sulfoxide, Methionine, 1-Methylhistidine, 3-Methylhistidine, Ornithine, Phenylalanine, Phosphoethanolamine, Phosphoserine, Proline,
Sarcosine, Serine, Taurine, Threonine, Tryptophan, Tyrosine, Valine, Urine Only Creatinine and Urea
High Sensitivity C-Reactive Protein

Celiac Disease Test (2 - 4 weeks)

Transglutaminase Antibody, Confirmatory test for Celiac Disease

Ceruloplasmin Test (1 - 3 weeks)

Ceruloplasmin

Comprehensive Fatty Acids Test

Total Saturated, Total Monounsaturated, Total Polyunsaturated, Total Omega 3, Total Omega 6, Total Fatty Acids. Omega 3 Series: Alpha-Linolenic,
Eicosapentaenoic, Docosapentaenoic, Docosahexaenoic. Omega 6 Series: Linoleic, Gamma-Linolenic, Dihomo-Gamma-Linolenic, Arachidonic,
Docosapentaenoic, Docosatetraenoic. Omega 9 Series: Eicosatrienoic. Monosaturated Series: Lauroleic, Myristoleic, Palmitoleic, Hexadecenoic, Vaccenic,
Oleic, Nervonic. Saturated: Caprylic, Lauric, Myristic, Palmitic, Stearic, Arachidic, Docosanoic, Tetracosanoic, Hexacosanoic. Branched-chain: Pristanic,
Phytanic. Ratios: Triene-to-Tetraene.
Bacterial culture: 73 potential species of imbalanced and dysbiotic bacteria, 4 species of beneficial bacteria. Yeast (Mycology) culture: 48 potential yeast and
fungal species. Parasite isolation: 22 potential parasites. Digestion and Absorption markers: Elastase, Fat Stain, Muscle Fibers, Vegetable fibers, and
Carbohydrates. Inflammation markers: Lysozyme, Lactoferrin, White Blood Cells, Mucus. Immunology: Secretory Immunoglobulin A (sIgA). Short Chain Fatty
Acids: Acetate, Propionate, Butyrate, Valerate. Intestinal Health markers: Red Blood Cells, pH, Occult Blood, Yeast (microscopy). Yeast sensitivity to:
Fluconazole, Itraconazole, Nystatin, Flucytosin, Berberine, Caprylic acid, Uva Ursi, Goldenseal, Tanalbit, Oregano. Bacterial sensitivity to: Augmentin,
Cefpodoxime, Cefuroxime, Ciprofloxacin, Tetracycline, Trimeth-sulfa, Berberine, Black Walnut, Caprilic Acid, Cats Claw, Goldenseal, Mastica, Oregano, Uva Ursi

1 - 3 weeks

Comprehensive Stool Analysis


2 - 4 weeks

Copper Test (1 - 3 weeks)

Copper

Copper / Zinc Profile (1 - 3 weeks)

Bound Copper, Unbound Copper, Total Copper, Zinc, Ceruloplasmin

DNA Methylation Pathway Profile

ACAT / 1-02, AHCY 1/2/19, BHMT 1, 3, 4, 8, CBS C699T/ A360A/ N212N, COMT V158M, H62H, 61, MAO A/ R297R, MTHFR C677T/A1298C/3, MTR/ A2756G,
MTRR, A66G/H595Y/K350A/R415T/S257T/11, NOS / D298E, SHMT/ C1420T, SUOX/ S370S, VDR Taq1/ Fok1

5 6 weeks

Gluten / Casein Peptides Test


1 - 2 weeks

Gliadorphin (peptide from wheat) and Casomorphin (peptide from dairy products)

GPL3 (2 - 3 weeks)

See Organic Acids Test (OAT) (74), Metals Hair Test (39) and IgG Food Allergy Test w/ Candida (94)

GPL4-DBS (2 - 3 weeks)

See Organic Acids Test (OAT) (74), IgG Food Allergy Test w/ Candida (94), Metals Hair Test (39) and Phospholipase A2 Activity

GPL4-Serum (2 - 3 weeks)

See Organic Acids Test (OAT) (74), IgG Food Allergy Test w/ Candida (94), Metals Red Blood Cell Test (18) and Phospholipase A2 Activity

GPL-TOX (11) (1 2 weeks)

2-,3-,4-Methylhippuric Acid (2MHA, 3MHA,4MHA), 2,4-Dichlorophenoxyacetic Acid (2,4D), 2-Hydroxyisobutyric Acid (2HIB), 3-Phenoxybenzoic Acid (3PBA),
Diethylphosphate (DEP), Dimethylphosphate (DMP), Monoethyl Phthalate (MEP), N-acetyl phenyl cysteine (NAP), Phenylglyoxylic Acid (PGO), Thiodiglycolic
Acid (TDG), Tiglyglycine (TG)

Hormones Comprehensive Panel


1 - 3 weeks

Hormones Comprehensive Plus Panel


1 - 3 weeks

Hormone Short Comprehensive Panel


1 - 3 weeks

Estradiol, Progesterone, Testosterone, DHEA, am/noon/evening/pm Cortisol


Estrone, Estradiol, Estriol, Progesterone, Testosterone, DHEA, am/noon/evening/pm Cortisol
Estradiol, Progesterone, Testosterone, DHEA, am /pm Cortisol

IgE Allergy Advanced Combined Test


See IgE Food Allergy Advanced Test (93) and IgE Inhalant Allergy Advanced Test (69) for test descriptions.
(93 / 69)
1 - 2 weeks

IgE Food Allergy Essentials Test (12)


1 - 2 weeks

Almond, Beef, Chicken, Corn, Egg White, Milk, Orange, Peanut, Shrimp, Soybean, Tomato, Wheat

IgE Food Allergy Basic Test (25)


1 - 2 weeks

IgE Food Allergy Advanced


Test (93)
1 - 2 weeks

IgE Inhalant Allergy Basic Test (36)


1 - 2 weeks

IgE Inhalant Allergy Advanced


Test (69)
1 - 2 weeks

Almond, Apple, Barley, Bean (White), Beef, Chicken, Chocolate, Corn, Egg (Whole), Garlic, Milk, Oat, Onion, Orange, Peanut, Pork, Potato, Rice, Shellfish Mix
(Cod, Shrimp, Mussel, Tuna, Salmon), Soybean, Tomato, Tuna, Vegetable Mix (Green Bean, White Bean, Carrot, Potato), Wheat, Yeast (Bakers)
Almond, Apple, Apricot, Asparagus, Avocado, Banana, Barley, Beef, Beet, Blueberry, Broccoli, Buckwheat, Cabbage, Cane Sugar, Carrot, Casein, Cashews,
Celery, Cheese, Chicken, Coconut, Cod Fish, Cocoa, Coffee, Corn, Crab, Cranberry, Eggplant, Egg White, Egg Yolk, Flax, Garbanzo Bean, Garlic, Gluten, Goats
Milk Cheese, Grape, Grapefruit, Green Bean, Green Pepper, Halibut, Hazelnut, Honey, Kidney Bean, Lamb, Lemon, Lentil, Lettuce, Lima Bean, Lobster, Mango,
Milk, Millet, Mushroom, Oat, Onion, Orange, Papaya, Pea, Peach, Peanut, Pear, Pecan, Pineapple, Pinto Bean, Pistachio, Plum, Pork, Potato, Pumpkin, Radish,
Raisin, Rice, Rye, Salmon, Sardine, Sesame, Shrimp, Soybean, Spinach, Strawberry, Sunflower, Sweet Potato, Tomato, Turkey, Tuna, Walnut, Watermelon,
Wheat, Whey, Yogurt, Yeast (Bakers), Yeast (Brewers), Zucchini
Alder (Speckled), Alternaria, Ash (White), Aspergillus, Beech (American), Bermuda Grass, Birch (Common Silver), Box Elder (Maple), Burning Bush, Cat,
Cladosporium, Cocklebur, Cockroach, Cottonwood Tree, Dog, Elm (White), Hickory (White), House Dust, Lambs Quarters, Marsh Elder (Rough), Meadow
Fescue, Mite (D. Farinae), Mugwort, Nettle, Oak (White), Orchard Grass/Cocksfoot, Penicillium, Pigweed, Pine Ponderosa, Plantain (English), Privet, Ragweed
(Short), Rye (Perennial), Sheep Sorrel, Sycamore (American), Timothy Grass
Acacia, Alder (Smooth), Alternaria, Amoxicillin, Ash (White), Aspergillus, Bahia Grass, Bermuda Grass, Bluegrass (Kentucky), Box Elder (Maple), Brome Grass,
Candida, Cat, Cedar (Mountain), Cladosporium, Cocklebur, Cockroach, Corn (Cultivated), Cottonwood Tree, Cypress (Bald), Dockweed (Yellow), Dog, Elm (American
and Fall Blooming), Ferret, Fescue (Meadow), Gerbil, Goldenrod, Hickory (White), House Dust, Iodine Bush, Johnson Grass, Lambs Quarters, Maple (Red), Marsh
Elder (Rough), Mexican Tea, Mite (D. Farinae), Mouse, Mulberry (Red and White), Nettle, Oak (Live, White, and Red), Oats, (Cultivated), Oat Grass Tall, Pecan Tree,
Penicillium, Pigweed (Spiny and Rough), Plantain (English), Poplar (White), Privet, Rabbit, Ragweed (Giant and Short), Rye (Cultivated), Rye Grass (Perennial), Salt
Cedar, Salt Grass, Sheep Sorrel, Sweet Gum, Sycamore, Timothy Grass, Tree of Heaven, Walnut (Black), Western Water Hemp, Wheat (Cultivated), Willow (Black)

IgG Food Allergy Test w/ Candida (94) Almond, Apple, Apricot, Asparagus, Avocado, Bakers Yeast (Saccharomyces cerevisiae), Banana, Barley, Beef, Beet, Blueberry, Brewers Yeast

(Saccharomyces cerevisiae),Broccoli, Buckwheat, Cabbage, Candida albicans, Cane Sugar, Carrot, Cashews, Casein, Celery, Cheese, Chicken, Cocoa, Coconut,
Cod fish, Coffee, Corn, Crab, Cranberry, Eggplant, Egg White, Egg Yolk, Flax, Garbanzo Beans, Garlic, Gliadin, Goats Milk Cheese, Grape, Grapefruit, Green
Bean, Green Pepper, Halibut, Hazelnut, Honey, Kidney Bean, Lamb, Lemon, Lentil, Lettuce, Lima bean, Lobster, Milk, Millet, Mozzarella Cheese, Mushroom, Oat,
Onion, Orange, Papaya, Pea, Peach, Peanut, Pear, Pecan, Pineapple, Pinto Bean, Pistachio, Plum (Prune), Pork, Potato, Pumpkin, Radish, Rice, Rye, Salmon,
Sardine, Sesame, Shrimp, Sorghum, Soybean, Spinach, Strawberry, Sunflower, Sweet Potato, Tomato, Tuna, Turkey, Wheat Gluten, Walnut, Watermelon,
Wheat, Whey, Yogurt

1 - 2 weeks

IgG Food Allergy Test w/ Candida + IgE


See IgG Food Allergy Test w/ Candida and IgE Food Allergy Essentials Test for test descriptions.
Food Allergy Essentials Test
1 - 2 weeks

IgG Asian Food Allergy Test


w/ Candida (94)
1 - 2 weeks

Immune Deficiency Profile


1 - 3 weeks

Kryptopyrrole Test

Abalone, Adzuki Bean, Almond, Apple, Bamboo Shoot, Banana, Barley, Beef, Black Pepper, Bonito, Buckwheat, Burdock (Gobo), Cabbage, Candida albicans,
Carrot, Casein, Cauliflower, Celery, Cheese, Cherry, Chestnut, Chicken, Clam, Cocoa, Coconut, Coffee, Corn, Crab, Cucumber, Curry Powder, Duck, Egg,
Eggplant, Garlic, Ginger, Grape, Green Bean, Green Pepper, Green Tea, Honey, Jack Mackerel, Kiwi, Kombu (Kelp), Lamb, Laver (Nori), Lettuce, Lotus Root,
Mackerel, Mango, Melon, Milk, Miso, Mushroom-Enoki, Mushroom-Shiitake, Mustard, Oat, Olive, Onion, Oolong Tea, Orange, Oyster, Pacific Saury, Pea, Peach,
Peanut, Pear, Pineapple, Pistachio, Pork, Potato, Pumpkin, Radish-Daikon, Red Pepper, Rice, Rye, Salmon, Sardine, Seaweed (Wakame), Sesame, Shrimp,
Soybean, Spinach, Squid, Strawberry, Sunflower, Sweet Potato, Tomato, Tuna, Vanilla Bean, Wheat, Wheat Gluten, Whey, Yeast (Brewers), Yogurt
Immunoglobulins IgA, IgM, IgE, IgG and IgG Subclasses 1, 2, 3 and 4, and Zinc
Kryptopyrrole

2 - 3 weeks

Metals Fecal Test (13)


2 - 3 weeks

Metals Hair Test (39)

Toxic: Antimony, Arsenic, Beryllium, Bismuth, Cadmium, Copper, Lead, Mercury, Nickel, Platinum, Thallium, Tungsten, Uranium
Nutritional: Calcium, Magnesium, Sodium, Potassium, Copper, Zinc, Manganese, Chromium, Vanadium, Molybdenum, Boron, Iodine, Lithium, Phosphorus, Selenium,
Strontium, Sulfur, Barium, Cobalt, Iron, Germanium, Rubidium, Zirconium. Ratios: Calcium/Magnesium, Sodium/Potassium, Zinc/Copper, Zinc/Cadmium,
Calcium/Phosphorus Toxic: Aluminum, Antimony, Arsenic, Beryllium, Bismuth, Cadmium, Lead, Mercury, Platinum, Thallium, Thorium, Uranium, Nickel, Silver, Tin,
Titanium

2 - 3 weeks

Metals Red Blood Cell Test (18)


2 - 3 weeks

Metals Urine Test (37)


2 - 3 weeks

Metals Whole Blood Test (20)


2 - 3 weeks

Microbial Organic Acids Test (MOAT) (21)


1 - 2 weeks

Microbial Organic Acids Test + Yeast


Culture w/ Sensitivity Test Combo
2 - 3 weeks

Organic Acids Test (OAT) (74)


1 - 2 weeks

Organic Acids Test +


Amino Acids Urine Test Combo

Nutritional: Boron, Chromium, Calcium, Copper, Iron, Magnesium, Manganese, Molybdenum, Phosphorus, Potassium, Selenium, Vanadium, Zinc Toxic:
Arsenic, Cadmium, Lead, Mercury, Thallium
Nutritional: Boron, Calcium, Chromium, Cobalt, Copper, Iron, Magnesium, Manganese, Molybdenum, Phosphorus, Potassium, Selenium, Sodium, Strontium,
Sulfur, Vanadium, and Zinc Toxic: Aluminum, Antimony, Arsenic, Barium, Beryllium, Bismuth, Cadmium, Cesium, Gadolinium, Lead, Mercury, Nickel, Palladium,
Platinum, Tellurium, Thallium, Thorium, Tin, Tungsten, Uranium
Nutritional: Calcium, Copper, Lithium, Magnesium, Manganese, Molybdenum, Selenium, Strontium, Zinc Toxic: Arsenic, Barium, Cadmium, Cobalt, Lead,
Mercury, Nickel, Platinum, Silver, Thallium, Uranium
Citramalic, 5-Hydroxymethyl-2-Furoic, 3-Oxoglutaric, Furan-2,5-Dicarboxylic, Furancarbonylglycine, Tartaric, Arabinose, Carboxycitric, Tricarballylic, 2Hydroxyphenylacetic, 4-Hydroxyphenylacetic, 4-Hydroxybenzoic, 4-Hydroxyhippuric, HPHPA (Clostridia marker), 4-Cresol, DHPPA (beneficial bacteria), Hippuric,
3-Indoleacetic, 3-Hydroxy-3-methylglutaric, 2-Hydroxyhippuric, Creatinine
See Microbial Organic Acids Test and Yeast Culture w/ Sensitivity Test for test descriptions.
Citramalic, 5-Hydroxymethyl-2-furoic, 3-Oxoglutaric, Furan-2,5-dicarboxylic, Furancarbonylglycine, Tartaric, Arabinose, Carboxycitric, Tricarballylic, 2-Hydroxyphenylacetic, 4Hydroxyphenylacetic, 4-Hydroxybenzoic, 4-Hydroxyhippuric, Hippuric, 3-Indoleacetic, Succinic, HPHPA (Clostridia marker), 4-Cresol (C. difficile), DHPPA (beneficial bacteria),
Glyceric, Glycolic, Oxalic, Lactic, Pyruvic, 2-Hydroxybutyric, Fumaric, Malic, 2-Oxoglutaric, Aconitic, Citric, Homovanillic Acid (HVA), Vanillmandelic Acid (VMA), HVA/VMA
Ratio, 5-Hydroxyindoleacetic (5-HIAA), Quinolinic, Kynurenic, Quinolinic / 5-HIAA Ratio, Uracil, Thymine, 3-Hydroxybutyric, Acetoacetic, 4-Hydroxybutyric, Ethylmalonic,
Methylsuccinic, Adipic, Suberic, Sebacic, Methylmalonic (Vitamin B12), Pyridoxic (Vitamin B6), Pantothenic (Vitamin B5), Glutaric (Vitamin B2-Riboflavin), Ascorbic (Vitamin C),
3-Hydroxy-3-methylglutaric (Vitamin Q10-CoQ10), N-Acetylcysteine (Glutathione precursor and chelating agent), Methylcitric (Vitamin H-Biotin), Pyroglutamic, Orotic, 2Hydroxyhippuric, 2-Hydroxyisovaleric, 2-Oxoisovaleric, 3-Methyl-2-oxovaleric, 2-Hydroxyisocaproic, 2-Oxoisocaproic, 2-Oxo-4-methiolbutyric, Mandelic, Phenyllactic,
Phenylpyruvic, Homogentisic, 4-Hydroxyphenyllactic, N-Acetylaspartic, Malonic, 3-Methylglutaric, 3-Hydroxyglutaric, 3-Methylglutaconic, Phosphoric, Creatinine
See Organic Acids Test and Amino Acids Urine Test for test descriptions.

1 - 3 weeks

Organic Acids Test + IgG Food Allergy


See Organic Acids Test and IgG Food Allergy Test w/ Candida for test descriptions.
Test w/ Candida Combo
1 - 3 weeks

Organic Acids Test + Yeast Culture w/


See Organic Acids Test and Yeast Culture w/ Sensitivity Test for test descriptions.
Sensitivity Test Combo
2 - 3 weeks

Phospholipase A2 Activity Test


1 - 2 weeks

Porphyrins Profile
Prealbumin Test

(2 - 3 weeks)
(1 - 3 weeks)

Streptococcus Antibodies Profile


1 - 3 weeks

Uric Acid Test (1 - 3 weeks)

Phospholipase A2 Activity
Coproporphyrin I and III (CP), Heptacarboxy (7-CP), Hexacarboxy (6-CP), Pentacarboxy (5-CP), Precoproporphyrin (PreCP), Uroporphyrins (UP)
Prealbumin
DNase antibodies in serum (ADB); Antistreptolysin O titer (ASO)
Uric Acid, Creatinine

Vitamin D Test: Serum


25-Hydroxyvitamin D2 (ergocalciferol), 25-Hydroxyvitamin D3 (cholecalciferol)
Vitamin D Test: Dried Blood Spot (DBS)
Serum: 2 - 3 weeks DBS: 3 - 4 weeks

Yeast Culture w/ Sensitivity Test


2 - 3 weeks

Yeast (Mycology) culture: 48 possible yeast and fungal species; Yeast (microscopy - visible presence of yeast cells); Yeast sensitivity to: Berberine, Caprylic
Acid, Uva Ursi , Tannic Acid, Oregano, Undecylenic Acid, Citrus Seed Extract, Nystatin, Fluconazole, Itraconazole, Ketoconazole

Zinc Test (2 - 3 weeks)

Zinc

PLEASE NOTE: *SST tubes are not sent in international test kits - Navy blue top tubes with (no additive) are provided in international test kits.
Revised 07/10/15

Turn-Around-Times and Specimen Collection

Turn-Around-Times
and Specimen
Collection

Turn-Around-Times and Specimen Collection

70mLUrineCollectionCup
70mLUrineCollectionCup
4Tubes
4Tubes
4Tubes
1SerumSeparatortube(goldtop)
2SerumSeparatortube(goldtop)
3SerumSeparatortubes(goldtop)
2SerumSeparatortubes(goldtop)
3SerumSeparatortubes(goldtop)
6SerumSeparatortubes(goldtop)
1SerumSeparatortube(goldtop)
Notubes/DBSBloodCollectionCard

GPLTOX(ToxicOrganicChemicalProfile)

Gluten/CaseinPeptidesTest

HormonesComprehensivePanel

HormonesComprehensivePlusPanel

HormonesShortComprehensivePanel

IgEFoodAllergyEssentialsTest(12)
IgEFoodAllergyBasicTest(25)
IgEFoodAllergyAdvancedTest(93)
IgEInhalantAllergyBasicTest(36)
IgEInhalantAllergyAdvancedTest(69)
IgEAllergyAdvancedCombinedTest(93/69)
IgGFoodAllergyTestw/Candida Serum
IgGFoodAllergyTestw/Candida DBS
IgGFoodAllergyTestw/Candida+IgEFoodAllergy
EssentialsTest
ImmuneDeficiencyProfile
KryptopyrroleTest(USAonly)
MetalsWholeBloodTest

2Bluetoptubes(PotassiumEDTA)
70mLUrineCollectionCup

MetalsUrineTest

2Bluetoptube(noadditive)
Amberplasticvial(w/additive),frozen,packonice
1Bluetoptube(PotassiumEDTA)
1whiteorbluecappedtubeprovided,nomorethan7days
old
Collectfromnapeoftheneck

MetalsRedBloodCellTest

MetalsHairTest

MetalsFecalTest

1Bluetoptube(noadditive)
2Bluetoptube(noadditive)
1SerumSeparatortube(goldtop)
Notubes/DBSBloodCollectionCard
1SerumSeparatortube(goldtop)

CopperTest
Copper/ZincProfile
CReactiveProteinTest(hsCRP)
DNAMethylationPathwayProfile
FerritinTest(onlyavailableinpanels)

1SerumSeparatortube(goldtop)

2yellow,1green,1white(frozen),nomorethan5daysold

1SerumSeparatortube(goldtop)
1Bluetoptube(noadditive)
1SerumSeparatortube(goldtop)ForUS1
Bluetoptube(noadditive)CanadaGelPouch

ComprehensiveStoolAnalysis(CSAP2)

ComprehensiveFattyAcidsTest(USA&Canada)

CeliacDiseaseTest
CeruloplasminTest

AminoAcidUrineTest(43)

70mLUrineCollectionCup,Bluespecimenvialtothefill
line,packonice

2SerumSeparatortube(goldtop)
1Lavendertop(EDTA)tube;(overnightfast)mixedwithacid
tube

AdvancedCholesterolProfile

AminoAcidPlasmaTest(USAonly)

TypeofTube/Vial

Test

FirstMorn.Urine,24hrortimed
urineFreezeSample

PackedCells

Hair

Stool

Serum
Urine
WholeBlood

Serum

Serum
Serum
Serum
DriedBloodSpot
Serum
FirstMorningUrineFreeze
Sample
FirstMorningUrineFreeze
Sample
CollectsalivaFour(4)timesin
oneday
CollectsalivaFour(4)timesin
oneday
CollectsalivaFour(4)timesin
oneday
Serum
Serum
Serum
Serum
Serum
Serum
Serum
DriedBloodSpot

Stool

Serum

Serum
Serum

FirstMorningUrineor24hr
UrineFreezeSample

Plasma

Serum

TypeofSpecimen

2mL

Requested
Amount
4mL

FillLine

4mL
10mL
7mL

3mL

40mL

50mL

.25grams
1gram
2mLPk
4mLPkCells
Cells

1/2full

3mL
8mL
7mL

2mL

EachTube
3/4full
EachTube
3/4full
EachTube
3/4full
2mL
5mL
8mL
5mL
8mL
12mL
1mL
5spots

EachTube
3/4full
EachTube
3/4full
EachTube
3/4full
1mL
2mL
6mL
3mL
5mL
10mL
.5mL
3spots

23weeks

23weeks

23weeks

23weeks

13weeks
23weeks
23weeks

12weeks

12weeks
12weeks
12weeks
12weeks
12weeks
12weeks
12weeks
12weeks

710businessdays

710businessdays

710businessdays

12weeks

10mL
5mL

13weeks
13weeks
13weeks
45Weeks
13weeks

24weeks

13weeks

12weeks

3mL
4mL
1mL
5spots
3mL

FillLine

2mL

13weeks
13weeks

24Weeks

24Weeks

24Weeks

TurnAroundTime

10mL

5mL

2mL
3mL
.5mL
3spots
2mL

1mL

20mL,blue
25mL,blue
vialtofill
vialtofillline
line
2mL
3mL
1mL
2mL

1mL

Absolute
Minimum
3mL

TurnAroundTimes&SpecimenRequirements

70mLUrineCollectionCup
70mLUrineCollectionCup
70mLUrineCollectionCup
1SerumSeparatortube(goldtop)
1Amberplasticvial,noadditive(lightsensitive)
1SerumSeparatortube(goldtop)
70mLUrineCollectionCup

MicrobialOrganicAcidsTest(MOAT)(20)

OrganicAcidsTest(72)

PhospholipaseA2ActivityTest

PrealbuminTest
PorphyrinsProfile
StreptococcusAntibodiesProfile

UricAcidTest(24HrorRandom)

FirstMorningUrineFreeze
Sample
FirstMorningUrineFreeze
Sample
FirstMorningUrineFreeze
Sample
Serum
Urine
Serum
FirstMorningUrineor24hr
FreezeSample

TypeofSpecimen

10mL

1mL
10mL
3mL

.5mL
5mL
2mL
5mL

10mL

10mL

10mL

Requested
Amount

5mL

5mL

5mL

Absolute
Minimum

13weeks

13weeks
23weeks
13weeks

12weeks

12weeks

12weeks

TurnAroundTime

YeastCulturew/SensitivityTest

1greenororangecappedtubeprovided,nomorethan7
23weeks
Stool
FillLine
daysold
VitaminDTestSerum
1SerumSeparatortube(goldtop)
Serum
1mL
2mL
23weeks
VitaminDTestDBS
Notubes/DBSBloodCollectionCard
DriedBloodSpot
3spots
5spots
34weeks
ZincTest
1Bluetoptube(noadditive)
Serum
1mL
2mL
13weeks
Pleasenote:ForInternationalTestKitsBlueTopTubesaresentinplaceofSerumSeparatorTubes(goldtop).Updated7/13/15

TypeofTube/Vial

Test

TurnAroundTimes&SpecimenRequirements

Specimen Collection & Shipping Instructions


The following test instructions are available for download on our website at
www.greatplainslaboratory.com/home/eng/sample.asp.
All test instructions are shipped with each kit.

Blood Tests & Phlebotomy Blood Draw Instructions


Comprehensive Stool Analysis (Thermo bag version)
Comprehensive Stool Analysis (Styrofoam version)
DMSA Challenge Test for Heavy Metal Poisoning
Dried Blood Spot (DBS) Test
Metals Fecal Test
Metals Hair Test
Organic Acids Test (OAT) + IgG Food Allergy w/ Candida Test Combo (DBS)
Organic Acids Test (OAT) + IgG Food Allergy w/ Candida Test Combo (Serum)
Organic Acids Test (OAT) + Yeast Culture w/ Sensitivity Test Combo
Urine Tests (Thermo bag version)
Urine Tests (Styrofoam version)
Yeast Culture w/ Sensitivity Test
Test Panels Instructions (U.S. Only)

Blood Draw Service Options


If you do not have a phlebotomist and are interested in ordering blood tests:

We recommend using Any Lab Test Now. Visit www.anylabtestnow.com/locations to find a


location near you.

For the Los Angeles and Orange County Areas: (MPS) Mobile Phlebotomy Services can do blood draw
from your home. The cost is $80. Call 909-985-5562 to make appointment. Standard hours of operation
are 6:00 a.m. to 3:00 p.m.

Other options (We recommend contacting these service providers first as we cannot guarantee that they will
provide blood draw services):

LabCorp or Quest Diagnostics

We recommend that physicians set up an account and advise the laboratory prior to referring patients for blood draw
services. We also recommend taking a GPL test kit to the laboratory and discussing the process together.

Local Hospital
Childrens Hospital
Urgent Care
Local Medical School
Suggestions from patients insurance company
An associate in another office that has a phlebotomist

Phlebotomists customarily charge a fee for the blood draw, which most insurances companies cover.
For the IgG Food Allergy Test, try the popular and convenient dry blood spot instead that you can
perform in-home.

Turn-Around-Times and Specimen Collection

Insurance Billing, CPT & ICD-9 Codes

Insurance Billing,
CPT & ICD-9 Codes

Insurance Billing, CPT & ICD-9 Codes

Revised
7/10/15

Insurance Overview
Provider
Blue Cross Blue Shield
(BCBS)

Contracted Plans
BCBS of Illinois
BCBS of Kansas City
PPO
BCBS of Minnesota
BCBS of Vermont

BCBS of Illinois: Comprehensive Stool


Analysis not covered*
Capital Blue Cross, Highmark, and
Blue Shield of California: IgG Food
Allergy Test w/ Candida not covered*

Blue Cross of Idaho PPO

Federal Employee
Program

Blue Shield of California*


*Blue Shield Covered

Highmark Blue Shield


of Pennsylvania

California and plans that


begin with ID# XEK
are Non-Contracted
Plans, see guidelines
below.

Keystone Health Plan


West - Pennsylvania
(HMO)
Highmark West Virginia

Capital Blue Cross


of Pennsylvania

Contracted
Insurance
Providers

Restrictions

Carefirst BCBS
includes Maryland,
Washington DC, and
parts of Northern
Virginia

Tricare

Tricare Prime
Tricare Standard
Tricare for Life

Medicare

Medicare
Medicare Advantage PPO

*These tests must be paid in full at the time of


Service

Tests not covered: Microbial Organic


Acids Test, Porphyrins Profile,
Kryptopyrrole Test, Comprehensive
Fatty Acids Test. Hormones Panels
cannot be billed for Tricare South
Medicare Advantage HMO
For non-eligible tests, refer to the
Advance Beneficiary Notice (ABN)
included in the Test Requisition Form

Medicare/Medicare Advantage does not pay for tests for which the documentation, including the
patient record, does not support that the tests were reasonable or necessary, and does not cover
routine screening tests. It is the responsibility of the ordering physician to document and maintain
the medical necessity of each test in the patients medical record.
Requirements:
Comprehensive Stool Analysis requires payment of $94.44
Signed ABN required (see Test Requisition Form)

Provider
Non-contracted Blue
Cross Blue Shield
(BCBS)
Anthem Blue Cross of
California
Blue Cross of
Massachusetts HMO
Cigna
Harvard Pilgrim
Tufts
United Healthcare

Non-Contracted
Plans

Non-Covered Tests

Eligibility
All Non-Contracted plans will require a 20% down
payment (see price list)
Any restricted plans or tests must pay in full at the
time of service

Restrictions
Contracted Insurance Providers and
Non-Covered Plans
IgG Food Allergy Test not covered for:
Anthem BCBS of California
BCBS of North Carolina

The Great Plains Laboratory files the insurance claim on behalf of the patient. Some insurance
companies provide payment and Explanation of Benefits (EOB) to the patients directly. If the
patient is paid directly, the endorsed check and EOB must be forwarded to The Great Plains
Laboratory (endorse back of check: Pay to the order of The Great Plains Laboratory and sign).

Amino Acids Plasma or Urine Test

DNA Methylation Pathway Profile

Kryptopyrrole Test

Phospholipase A2 Activity Test

GPL-TOX (Toxic Organic Chemical Profile)

We are not in-network with any of these plans and will not bill to these insurance carriers.
Full cash price payment required and must be submitted with specimens. A receipt will be sent to the patient.
HMO plans (except those listed
Aetna
UMR
above)
All non-eligible plans (see above)
United Healthcare of the River Valley

Non-Covered Plans

BCBS of Florida
BCBS of Iowa
BCBS of Arizona
BCBS of Texas

Humana

Wellmark BCBS of Iowa

Medicaid
Silver Direct Access (a plan under
Anthem Blue Cross of California)

Wellmark BCBS of South Dakota

GEHA

For any questions regarding insurance coverage, please call 913-341-8949 or 913-754-0459
Always call your insurance provider to confirm benefits as insurance coverage is subject to change. Patients are responsible for any
deductibles, copayments, cost shares, coinsurance, or balance. If for any reason your insurance company deems your lab work as a noncovered or medically unnecessary service, you will be responsible for the full amount of the charge.
We are currently applying for in-network coverage with several individual BCBS state programs. Please check our website for updated
information at www.GPL4U.com/Insurance_Overview. Also available at this location is our insurance coverage verification guide to assist in
determining coverage.
NOTE: Insurance is filed in the state where the referring physicians NPI is registered, or where the referring physician's NPI is currently located.
Page 1 of 1

Revised 07/10/15

Guide to Determining Insurance Coverage


By calling your insurance provider, you can verify your coverage and gather information to determine any
out-of-pocket expenses. This is not a guarantee of coverage or reimbursement from your insurance plan; rather, it is
meant to be a guide to determining whether to file insurance or to pay cash price. The Great Plains Laboratory will file
insurance for both contracted and non-contracted insurance plans (see insurance overview for participating carriers).

Before You Call


Have the following ready when you call your insurance company:
1) Your Insurance Card You will need the ID number and group number
2) CPT (Current Procedural Terminology) Codes On the next page of this guide
3) Diagnosis (ICD-9) Codes Must obtain these from your physician
4) The Great Plains Laboratory, Inc. Tax ID number is 48-1192412
5) The Great Plains Laboratory, Inc. NPI number is 1942282496

When You Call


1) Document Your Call
Insurance Representatives Name:__________________Date of Call:____________Time of Call:______

2) Verify Coverage
A) Tell the representative that you would like to verify coverage of laboratory tests. If they ask if this is medical
or routine, inform them it is medical.
B) Provide the gathered information above (see Before You Call)

3) Ask the following questions:


A)
B)
C)
D)

Is the test covered? Yes No If the answer is no you will need to pay the discounted cash price
How much of my deductible is remaining? $____________
What is my co-insurance? (Usually 20%-50%) __________
How much of my annual out-of-pocket expense is remaining? $____________

If your deductible or co-insurance is higher than the total cash amount, it is recommended to pay the cash price
then file with your insurance company once youve received your billing statement from the Great Plains
Laboratory. If the test is not covered, then pay the lower cash price.

Insurance Billing, CPT & ICD-9 Codes

CPT Codes
Revised 5/23/13

Test

CPT Code(s)

Comprehensive Hormone Panel

82670 84144 84402 82626 82530*4

Comprehensive Plus Hormone Panel

82679 82670 82677 84144 84402 82626 82530*4


82272 82492 82656 83516 83631 83986 85549 87045 87046
87102 87177*2 87209*2 87328 87329 89125 89160

Advanced Cholesterol Profile Serum


Amino Acids Plasma or Urine Test
C-Reactive Protein Test (hs-CRP) Serum
CBC Test w/ Differential Serum
Celiac Disease Test Serum
Ceruloplasmin Test Serum
Comprehensive Fatty Acids Test Serum

Comprehensive Stool Analysis Stool


Copper Test Serum
Copper / Zinc Profile Serum
Gluten / Casein Peptides Test Urine
GPL3

GPL4-DBS

GPL4-Serum
Hormones Comprehensive Panel
Hormones Comprehensive Plus Panel
Hormones Short Comprehensive Panel
IgE Allergy Advanced Combined Test (93/69) Serum
IgE Food Allergy Basic Test (25) Serum
IgE Food Allergy Advanced Test (93) Serum
IgE Inhalant Allergy Basic Test (36) Serum
IgE Inhalant Allergy Advanced Test (69) Serum
IgG Food Allergy Test w/ Candida (94) Serum/DBS
IgG Asian Food Allergy Test w/ Candida (94) Serum/DBS
Immune Deficiency Profile Serum
Metals Fecal Test (13)
Metals Hair Test (39)
Metals Red Blood Cell Test (18)
Metals Urine Test (38)
Metals Whole Blood Test (20)
Microbial Organic Acids Test (MOAT) (21) Urine
Organic Acids Test (OAT) (74) Urine
OAT + Amino Acids Urine Test Combo - Urine
OAT + IgG Food Allergy Test w/ Candida Combo
Urine & Serum/Dried Blood Spot (DBS)
Porphyrins Profile Urine
Prealbumin Test Serum
Short Comprehensive Hormone Panel
Streptococcus Antibodies Profile Serum
Uric Acid Test Urine
Vitamin D Test Serum/DBS
Yeast Culture w/ Sensitivity Test Stool
Zinc Test Serum

Insurance Billing, CPT & ICD-9 Codes

82172*2 82465 83090 83695 83718


82139*1 82140 82492 84540
86141
85027
82492
82390
82544*30 No Medicare Coverage

No Medicare Coverage

82525
82390 82525 84630
82570 83519*2 No Medicare Coverage
82108 82131 82300 82507 82525 82570 83018*28 83150 83497 83605
83655 83735 83785 83825 83885 83921*63 83945 84100 84207 84210
84255 84585 84591 84630 86001*93 86628 86671*2 No Medicare
Coverage
82108 82131 82300 82306 82507 82525 82542 82570 83018*28 83150
83497 83605 83655 83735 83785 83825 83885 83921*63 83945 84100
84207 84210 84255 84585 84591 84630 86001*93 86628 86671*2 No
Medicare Coverage
82131 82175 82300 82306 82310 82495 82507 82525 82542 82570
83015 83018*4 83150 83497 83605 83655 83735 83785 83825
83921*63 83945 84100 84132 84207 84210 84255 84585 84591 84630
86001*93 86628 86671*2
No Medicare Coverage
82670 84144 84402 82626 82530*4
82679 82670 82677 84144 84402 82626 82530*4
82670 84144 84402 82626 82530*2
86003*162 No Medicare Coverage
86003*25 No Medicare Coverage
86003*93 No Medicare Coverage
86003*36 No Medicare Coverage
86003*69 No Medicare Coverage
86001*93 86628 86671*2 No Medicare Coverage
86001*93 86628 86671*2 No Medicare Coverage
82784 82785 82787*4 84630
82175 82300 82525 83015 83655 83825 83885
No Medicare Coverage
82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100
84255 84630 No Medicare Coverage
82175 82300 82310 82495 82525 83015 83018*4 83655 83735 83785
83825 84100 84132 84255 84630
No Medicare Coverage
82108 82175 82300 82495 82525 82570 83018 83540 83655 83735
83785 83825 83885 84100 84133 84255 84300 84630 No Medicare
Coverage
82310 82495 82525 83018*7 83655 83735 83825 84132 84255 84285
84295 84630 No Medicare Coverage
82570 83921*20
82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210
84585 84591
82131 82139*1 82140 82507 82492 82570 83150 83497 83605
83921*63 83945 84207 84210 84540 84585 84591
86001*93 86628 86671 82131 82507 82570 83150 83497 83605
83921*63 83945 84207 84210 84585 84591
No Medicare Coverage
84120*6
84134
82670 84144 84402 82626 82530*2
83883 86215
84560
82306 82542 No Medicare Coverage
87102 87106 87184 87220
84630

CPT Codes: Test Panels


Basic Autism Panel
Comprehensive Stool Analysis

82272 82492 82656 83516 83631 83986 85549 87045 87046 87102 87177*2
87209*2 87328 87329 89125 89160 No Medicare Coverage

Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test

86001*93 86628 86671*2

Metals Hair Test

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

No Medicare Coverage
No Medicare Coverage

No Medicare Coverage

Comprehensive Autism Panel


Advanced Cholesterol Profile

82172*2 82465 83090 83695 83718

Comprehensive Stool Analysis

82272 82492 82656 83516 83631 83986 85549 87045 87046 87102 87177*2
87209*2 87328 87329 89125 89160 No Medicare Coverage

Copper/Zinc Profile

82390 82525 84630

Ferritin Test

82728

Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Immune Deficiency Profile

82784 82785 82787*4 84630

Metals Hair Test

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

Streptococcus Antibodies Profile

83883 86215

Vitamin D Test

82306 82542

No Medicare Coverage
No Medicare Coverage

No Medicare Coverage

No Medicare Coverage

Basic AD(H)D Panel


Comprehensive Fatty Acids Test

82544*30

Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Metals Hair Test

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

Page 1 of 5

No Medicare Coverage
No Medicare Coverage
No Medicare Coverage

No Medicare Coverage

Revised 01/15/14

Insurance Billing, CPT & ICD-9 Codes

Comprehensive AD(H)D Panel


Advanced Cholesterol Profile

82172*2 82465 83090 83695 83718

Amino Acids Urine Test

82139*1 82140 82492 84540

Comprehensive Fatty Acids Test

82544*30

Comprehensive Stool Analysis

82272 82492 82656 83516 83631 83986 85549 87045 87046 87102 87177*2
87209*2 87328 87329 89125 89160 No Medicare Coverage

Copper/Zinc Profile

82390 82525 84630

Ferritin Test

82728

Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Metals Hair Test

No Medicare Coverage

No Medicare Coverage
No Medicare Coverage

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

No Medicare Coverage

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

Streptococcus Antibodies Profile

83883 86215

Vitamin D Test

82306 82542

No Medicare Coverage

Basic Tourettes & Tics Panel


Advanced Cholesterol Profile

82172*2 82465 83090 83695 83718

Ferritin Test

82728

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Metals Hair Test

No Medicare Coverage

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

No Medicare Coverage

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

Streptococcus Antibodies Profile

83883 86215

Comprehensive Tourettes & Tics Panel


Advanced Cholesterol Profile

82172*2 82465 83090 83695 83718

Amino Acids Urine Test

82139*1 82140 82492 84540

Comprehensive Stool Analysis

82272 82492 82656 83516 83631 83986 85549 87045 87046 87102 87177*2
87209*2 87328 87329 89125 89160 No Medicare Coverage

Copper/Zinc Profile

82390 82525 84630

Ferritin Test

82728

Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Immune Deficiency Profile

82784 82785 82787*4 84630

Metals Hair Test

No Medicare Coverage
No Medicare Coverage

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

No Medicare Coverage

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

Streptococcus Antibodies Profile

83883 86215

Vitamin D Test

82306 82542

No Medicare Coverage

Page 2 of 5

Insurance Billing, CPT & ICD-9 Codes

Revised 01/15/14

Basic Fibromyalgia & CFS Panel


Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Metals Hair Test

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

No Medicare Coverage
No Medicare Coverage

No Medicare Coverage

Comprehensive Fibromyalgia & CFS Panel


Amino Acids Urine Test

82139*1 82140 82492 84540

C-Reactive Protein Test

86141

Comprehensive Stool Analysis

82272 82492 82656 83516 83631 83986 85549 87045 87046 87102 87177*2
87209*2 87328 87329 89125 89160 No Medicare Coverage

Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Metals Hair Test

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

Vitamin D Test

82306 82542

No Medicare Coverage
No Medicare Coverage

No Medicare Coverage

No Medicare Coverage

Basic Wellness Panel


Comprehensive Fatty Acids Test

82544*30

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Metals Hair Test

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

No Medicare Coverage
No Medicare Coverage

No Medicare Coverage

Comprehensive Wellness Panel


Advanced Cholesterol Profile

82172*2 82465 83090 83695 83718

Amino Acids Urine Test

82139*1 82140 82492 84540

Comprehensive Fatty Acids Test

82544*30

Copper/Zinc Profile

82390 82525 84630

Ferritin Test

82728

Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Metals Hair Test

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

Vitamin D Test

82306 82542

Page 3 of 5

No Medicare Coverage

No Medicare Coverage
No Medicare Coverage

No Medicare Coverage

No Medicare Coverage

Revised 01/15/14

Insurance Billing, CPT & ICD-9 Codes

Basic Mental Health Panel


Amino Acids Urine Test

82139*1 82140 82492 84540

Comprehensive Fatty Acids Test

82544*30

Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Metals Hair Test

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

No Medicare Coverage
No Medicare Coverage
No Medicare Coverage

No Medicare Coverage

Comprehensive Mental Health Panel


Advanced Cholesterol Profile

82172*2 82465 83090 83695 83718

Amino Acids Urine Test

82139*1 82140 82492 84540

Comprehensive Fatty Acids Test

82544*30

Comprehensive Stool Analysis

82272 82492 82656 83516 83631 83986 85549 87045 87046 87102 87177*2
87209*2 87328 87329 89125 89160 No Medicare Coverage

Copper/Zinc Profile

82390 82525 84630

Gluten/Casein Peptides Test

82570 83519*2

IgG Food Allergy Test w/ Candida

86001*93 86628 86671*2

Metals Hair Test

82108 82300 82525 83018*28 83655 83735 83785 83825 83885 84100 84255 84630

Organic Acids Test

82131 82507 82570 83150 83497 83605 83921*63 83945 84207 84210 84585 84591

Vitamin D Test

82306 82542

No Medicare Coverage

No Medicare Coverage
No Medicare Coverage

No Medicare Coverage

No Medicare Coverage

Page 4 of 5

Insurance Billing, CPT & ICD-9 Codes

Revised 01/15/14

ICD-9 Codes
Abnormal chemistry

790.6

Abnormal weight gain

783.1

Abnormal findings

796

ADD, without hyperactivity

314

ADHD, with hyperactivity

314.01

Adrenal disorder

255.8

Adrenal hypofunction

255.5

Allergic rhinitis

477

Allergic rhinitis

477

Allergies

995.3

Anxiety

300

Anxiety, generalized

300.02

Asthma, unspecificied; with acute exacerbation

493.92

Asthma, unspecified, with status asthmaticus

493.91

Asthma, unspecified;unspecified

493.9

Autoimmune disease

279.4

Bipolar

296.8

Candidiasis (insurance usually asks for two numbers)

112; 112.85

Celiac

579

Chronic fatigue syndrome

780.71

Constipation

564

Corticoadrenal insufficiency

255.4

Crohns

555

Delayed milestones

783.42

Depression

311

Depression, neurotic

300.4

Depression, recurrent

296.32

Depression psychosis, unspecified

296.2

Dermatitis

692.4

Diarrhea

787.91

Disorder of thyroid

246.9

Disorders of amino-acid transport and metabolism

270

Disorders of urea cycle metabolism

270.6

Disturbances of sulphur-bearing amino-acid metabolism

270.4

Dysmenorrhea

625.3

Endocrine disorder

259.9

Fatigue, weakness and lethargy

780.79

Please note that these change often and may need to be verified.

Revised 1/1/10

Insurance Billing, CPT & ICD-9 Codes

Fibromyositis/myalgia

729.1

Flatulence/bloating

787.3

Following psychotherapy and other treatment for mental disorder

V66.3

Following psychotherapy and other treatment for mental disorder

V67.3

Food allergy

693.1, 692.5

Functional diarrhea

564.5

Gastroenteritis, diarrhea

558.9

Gastrointestinal symptoms

787.9

Headache

784

Hyperglycemia

790.29

Hyperlipidemia

272.4

Hyperlipidemia, mixed

272.2

Hypersomnia due to mental disorder

327.15

Hypersomnia with sleep apnea

780.53

Hypoglycemia

251.2

Hypothyroidism

244.9

Immune disorders

279.9

Immunodeficiency, unspecified

279.03

Insomnia

780.52

Insomnia due to mental disorder

327.02

Irritable bowel syndrome

564.1

Irritable colon (Colitis)

564.1

Lipoprotein deficiencies

272.5

Malabsorption

579.9

Malabsorption of carbohydrates metabolism disorder

277.9

Metal Toxicity

985.9

Migraine, classical

346

Migraine, variants

346.2

Nutritional deficiency, unspecified

269.9

Obesity

278

Obesity, morbid

278.01

Observation for suspected mental condition

V71.09

Other mental disorders

V11.8

Other mental problems

V40.2

Other specified drug-induced mental disorders

292.8

Other specified mental disorders and developmental handicaps

V79.8

Other specified transient mental disorders due to conditions classified elsewhere

293.8

Other suspected mental condition

V71.09

Personal history of mental disorder

V11.8

Please note that these change often and may need to be verified.

Revised 1/1/10

Insurance Billing, CPT & ICD-9 Codes

Rhinitis due to pollen

477

Special screening for mental disorders and developmental handicaps

V79

Stomach dysfunction

536.9

Unspecified disorder of amino-acid metabolism

270.9

Unspecified disorder of calcium metabolism

275.4

Unspecified disorder of carbohydrate transport and metabolism

271.9

Unspecified disorder of lipoid metabolism

272.9

Unspecified disorder of metabolism

277.9

Unspecified disorder of mineral metabolism

275.9

Unspecified mental disorder and developmental handicap

V79.9

Unspecified mental or behavioral problem

V40.9

Unspecified mental retardation

319

Please note that these change often and may need to be verified.

Revised 1/1/10

Insurance Billing, CPT & ICD-9 Codes

Sample Test Requisition Form

Sample Test
Requisition Form

Sample Test Requisition Form

800-288-0383
www.GPL4U.com

Test Requisition Form


Information in RED is required to process sample.

Please print clearly.

Patient Information
First Name

Last Name

Address

City

Country

Male Female

Phone

Date of Birth (MM/DD/YYYY)

State

Zip

Age

Weight

Our laboratory does not accept specimens from patients who reside in or physicians who practice in the state of New York.

Person Responsible for Charges

(If different than above)

First Name

Last Name

Address

City

Country

State

Home Phone

Zip

Cell Phone

E-mail

Physician Information

(Signature required to process sample)

First Name

Last Name

Credentials

Institution
Address

City

Country

State

Phone

Zip

Fax

E-mail

NPI

Physician Signature

REQUIRED

ICD-9 Codes (required for insurance)

Method of Payment & Insurance Information (select one)


Bill Insurance (Non-Contracted) Must enclose 20% down payment
See price list attached for amount due and select payment type below.
Bill Insurance (Contracted)

See Insurance Overview on page 3 to determine whether your


insurance is considered contracted, non-contracted, or non-covered.
Medicare/Medicare Advantage must fill out Advance Beneficiary
Notice of Noncoverage (ABN) form.

Self Pay Must enclose full payment (select payment method below)
Check Money Order PayPal Visa MasterCard American Express Discover
Amount: $_______________________
Credit Card #: _______________________________________ Exp. Date: ________ Security Code: _____

MUST FILL OUT


TEST ORDERS ON
REVERSE

Name on Card: ____________________________________ Signature: ______________________________


Bill Physician Physicians Name: __________________________________________________________

Primary Insurance

(include photocopy of insurance card (both sides)

Secondary Insurance (include photocopy of insurance card (both sides)

Company & Plan Name (ex. BCBS of Kansas City)

Company & Plan Name (ex. BCBS of Kansas City)

Insurance Company Address

Insurance Company Address

City

State

Zip

City

State

Insurance Company Phone (required)

Insurance Company Phone (required)

Name of Insured

Name of Insured

Date of Birth of Insured (MM/DD/YYYY)

Patient Relationship to Insured

Date of Birth of Insured (MM/DD/YYYY)

Self Spouse Child Other


Subscriber #

Group #

Zip

Patient Relationship to Insured

Self Spouse Child Other


Subscriber #

Group #

I authorize and request payment of medical benefits be made directly to The Great Plains Laboratory for the requested lab work on this
Form. I authorize the release of any medical information necessary to process this claim. I understand that any reimbursement checks
and explanation of benefits (EOBs) received by the patient must be submitted to The Great Plains Laboratory. I agree to be personally and
fully responsible for any portion of the claim not covered by my insurance and agree to make such payment within 30 days. A service
charge of 1.5% per month may be charged on balances over 30 days. I permit a copy of this to be used in place of the original.
Patient/Guarantor Signature:

Date (MM/DD/YYYY):

Internal Use Only: O ____ A ____ DE ____ C ____ SR ____ Carevoyant # ______________ F ____ M ____ E ____ I ____ DR _________
Page 1 of 5

Revised 07/10/15

Date and time of collection REQUIRED to process specimens.

STOP

URINE:

Collection Date: __________ Time: ________


Has urine been frozen? Yes No

AM PM

STOOL 1: Collection Date: __________ Time: ________ AM PM


STOOL 2: Collection Date: __________ Time: ________ AM PM

BLOOD: Collection Date: __________ Time: ________ AM PM

URINE

HAIR:

Collection Date: __________ Time: ________

AM PM

BLOOD, SERUM & HAIR

Amino Acids Test (43) Random Collection 24 Hr. Total vol. ____ mL
Gluten / Casein Peptides Test
GPL-TOX (Toxic Organic Chemical Profile)
Kryptopyrrole Test
Metals Urine Test (38) (select type of collection)
Random
Timed

# of hrs. _____________ Total vol. _________ mL

24 Hr. Total vol. __________ mL


Pre or

Post Provoking agent __________ dosage ________

Microbial Organic Acids Test (MOAT) (21) (included in OAT)


Organic Acids Test (OAT) (74)
Phospholipase A2 Activity Test
Porphyrins Profile
Uric Acid Test Random Collection 24 Hr. Total vol. ____ mL
Other _______________________________________________

STOOL
Comprehensive Stool Analysis x 2
Metals Fecal Test (13) Pre or Post
Provoking agent _____________ dosage___________
Does the patient have dental amalgams?

Yes

No; If so, how many? ____

Yeast Culture w/ Sensitivity Test


Other _______________________________________________

COMBO TEST ORDERS *


Microbial Organic Acids Test + Yeast Culture w/ Sensitivity Test
Combo
Organic Acids Test + Amino Acids Urine Test Combo
Random Collection

24 Hr. Total vol. ____ mL

Amino Acids Plasma Test (43) (requires overnight fast)


Advanced Cholesterol Profile
C-Reactive Protein Test (hs-CRP)
Celiac Disease Test (Transglutaminase)
Ceruloplasmin Test
Comprehensive Fatty Acids Test (requires overnight fast and frozen sample)
Copper Test
Copper / Zinc Profile
DNA Methylation Pathway Profile
IgE Allergy Advanced Combined Test (93 foods & 69 inhalants)
IgE Food Allergy Essential Test (12)
IgE Food Allergy Basic Test (25)
IgE Food Allergy Advanced Test (93)
IgE Inhalant Allergy Basic Test (36)
IgE Inhalant Allergy Advanced Test (69)
IgG Food Allergy Test w/ Candida - Dried Blood Spot (DBS) (94)
IgG Food Allergy Test w/ Candida - Serum (94)
IgG Asian Food Allergy Test w/ Candida - Dried Blood Spot (DBS) (94)
IgG Asian Food Allergy Test w/ Candida - Serum (94)
Immune Deficiency Profile
Metals Test: Hair (39) Whole Blood (20) Red Blood Cell (18)
Prealbumin Test
Streptococcus Antibodies Profile
Vitamin D Test - Dried Blood Spot (DBS)
Vitamin D Test - Serum
Zinc Test
Other _______________________________________________

TEST PANEL ORDERS

Organic Acids Test + IgG Food Allergy Test w/ Candida Dried

Comprehensive Autism Panel

Blood Spot (DBS) Combo

Basic Autism Panel


Comprehensive AD(H)D Panel
Basic AD(H)D Panel
Comprehensive Tourettes & Tics Panel

Organic Acids Test + IgG Food Allergy Test w/ Candida Serum


Combo
Organic Acids Test + Yeast Culture w/ Sensitivity Test Combo
GPL3: Organic Acids Test + Metals Hair + IgG Dried Blood Spot
GPL4-DBS: Organic Acids Test + IgG Food Allergy Test w/ Candida
+ Metals Hair + Phospholipase A2 Activity Test
GPL4-Serum: Organic Acids Test + IgG Food Allergy Test w/
Candida + Red Blood Cell + Phospholipase A2 Activity Test
IgG Food Allergy Test w/ Candida + IgE Food Allergy Essential Test
* Combo discounts only apply for kits that arrive in same FedEx Clinical Pak

Basic Tourettes & Tics Panel


Comprehensive Fibromyalgia & CFS Panel
Basic Fibromyalgia & CFS Panel
Comprehensive Wellness Panel
Basic Wellness Panel
Comprehensive Mental Health Panel
Basic Mental Health Panel

NOTE: Individual tests


included in these panels
can be found on the
Price List.

GPL is required by law to maintain the privacy of your Protected Health Information. The complete privacy policy can be found online at www.gpl4u.com/privacy

May we use your test data for research purposes without any identifying information being released? Yes

No

If yes, please fill the boxes below as applicable to this patient.


ADD/ADHD
Alzheimers
Aspergers

Autistic symptoms
Chronic fatigue
Colitis

Crohns disorder
Depression
Down syndrome

Fibromyalgia
Irritable bowel
Multiple sclerosis

OCD
PDD
Psychosis

Schizophrenia
Tourette syndrome
Tic Disorder

Other (please list): _______________________________________________________________________________________________________________

Check here if you do not wish to receive future mailings and research updates from the Great Plains Laboratory, Inc.

Name: _______________________________________________ Signature:____________________________________ Date: ______________


Page 2 of 5

Revised 07/10/15

Revised
7/10/15

Insurance Overview
Provider
Blue Cross Blue Shield
(BCBS)

Contracted Plans
BCBS of Illinois
BCBS of Kansas City
PPO
BCBS of Minnesota
BCBS of Vermont

BCBS of Illinois: Comprehensive Stool


Analysis not covered*
Capital Blue Cross, Highmark, and
Blue Shield of California: IgG Food
Allergy Test w/ Candida not covered*

Blue Cross of Idaho PPO

Federal Employee
Program

Blue Shield of California*


*Blue Shield Covered

Highmark Blue Shield


of Pennsylvania

California and plans that


begin with ID# XEK
are Non-Contracted
Plans, see guidelines
below.

Keystone Health Plan


West - Pennsylvania
(HMO)
Highmark West Virginia

Capital Blue Cross


of Pennsylvania

Contracted
Insurance
Providers

Restrictions

Carefirst BCBS
includes Maryland,
Washington DC, and
parts of Northern
Virginia

Tricare

Tricare Prime
Tricare Standard
Tricare for Life

Medicare

Medicare
Medicare Advantage PPO

*These tests must be paid in full at the time of


Service

Tests not covered: Microbial Organic


Acids Test, Porphyrins Profile,
Kryptopyrrole Test, Comprehensive
Fatty Acids Test. Hormones Panels
cannot be billed for Tricare South
Medicare Advantage HMO
For non-eligible tests, refer to the
Advance Beneficiary Notice (ABN)
included in the Test Requisition Form

Medicare/Medicare Advantage does not pay for tests for which the documentation, including the
patient record, does not support that the tests were reasonable or necessary, and does not cover
routine screening tests. It is the responsibility of the ordering physician to document and maintain
the medical necessity of each test in the patients medical record.
Requirements:
Comprehensive Stool Analysis requires payment of $94.44
Signed ABN required (see Test Requisition Form)

Provider
Non-contracted Blue
Cross Blue Shield
(BCBS)
Anthem Blue Cross of
California
Blue Cross of
Massachusetts HMO
Cigna
Harvard Pilgrim
Tufts
United Healthcare

Non-Contracted
Plans

Non-Covered Tests

Eligibility
All Non-Contracted plans will require a 20% down
payment (see price list)
Any restricted plans or tests must pay in full at the
time of service

Restrictions
Contracted Insurance Providers and
Non-Covered Plans
IgG Food Allergy Test not covered for:
Anthem BCBS of California
BCBS of North Carolina

The Great Plains Laboratory files the insurance claim on behalf of the patient. Some insurance
companies provide payment and Explanation of Benefits (EOB) to the patients directly. If the
patient is paid directly, the endorsed check and EOB must be forwarded to The Great Plains
Laboratory (endorse back of check: Pay to the order of The Great Plains Laboratory and sign).

Amino Acids Plasma or Urine Test

DNA Methylation Pathway Profile

Kryptopyrrole Test

Phospholipase A2 Activity Test

GPL-TOX (Toxic Organic Chemical Profile)

We are not in-network with any of these plans and will not bill to these insurance carriers.
Full cash price payment required and must be submitted with specimens. A receipt will be sent to the patient.
HMO plans (except those listed
Aetna
UMR
above)
All non-eligible plans (see above)
United Healthcare of the River Valley

Non-Covered Plans

BCBS of Florida
BCBS of Iowa
BCBS of Arizona
BCBS of Texas

Humana

Wellmark BCBS of Iowa

Medicaid
Silver Direct Access (a plan under
Anthem Blue Cross of California)

Wellmark BCBS of South Dakota

GEHA

For any questions regarding insurance coverage, please call 913-341-8949 or 913-754-0459
Always call your insurance provider to confirm benefits as insurance coverage is subject to change. Patients are responsible for any
deductibles, copayments, cost shares, coinsurance, or balance. If for any reason your insurance company deems your lab work as a noncovered or medically unnecessary service, you will be responsible for the full amount of the charge.
We are currently applying for in-network coverage with several individual BCBS state programs. Please check our website for updated
information at www.GPL4U.com/Insurance_Overview. Also available at this location is our insurance coverage verification guide to assist in
determining coverage.
NOTE: Insurance is filed in the state where the referring physicians NPI is registered, or where the referring physician's NPI is currently located.
Page 3 of 5

Revised 07/10/15

(A) Notifier(s):
(B) Patient Name:

(C) Identification Number:

ADVANCE BENEFICIARY NOTICE OF NONCOVERAGE (ABN)


NOTE: If Medicare doesnt pay for the tests in section (D) below, you may have to pay.
Medicare does not pay for everything, even some care that you or your health care provider have good reason to think you need. We expect
Medicare may not pay for the tests in section (D) below.

(D)

(E) Reason Medicare May Not Pay:

Comprehensive Fatty Acids Test


Comprehensive Stool Analysis:
Lysozyme, Short Chain Fatty
Acids, Secretory IgA, Occult Blood

Medicare does not pay for experimental or research use tests.

$299.00

Medicare never pays for these tests.

$94.44

GPL-TOX (Toxic Organic Chemical Profile)

Medicare does not pay for experimental or research use tests.


Medicare does not pay for experimental or research use tests.
Medicare does not consider these tests to be medically necessary
Medicare does not consider these tests to be medically necessary
Medicare does not consider these tests to be medically necessary
Medicare does not consider these tests to be medically necessary
Medicare does not consider these tests to be medically necessary
Medicare does not consider these tests to be medically necessary
Medicare does not consider these tests to be medically necessary
Medicare does not pay for experimental or research use tests.
Medicare does not pay for experimental or research use tests.
Medicare does not pay for experimental or research use tests.
Medicare does not pay for experimental or research use tests.
Medicare does not pay for experimental or research use tests.
Medicare does not pay for experimental or research use tests.
Medicare does not pay for experimental or research use tests.
Medicare does pay for the Organic Acid Test, but does not pay
for the combo.
Medicare does not pay for this test for my condition.

$219.00
$119.00
$119.00
$379.00
$579.00
$379.00
$449.00
$325.00
$325.00
$129.00
$245.00
$245.00
$345.00
$299.00
$305.00
$99.00

Gluten/Casein Peptides Test


IgE Food Allergy Essential Test
IgE Food Allergy Basic Test
IgE Food Allergy Advanced Test
IgE Inhalant Allergy Basic Test
IgE Inhalant Allergy Advanced Test
IgG Food Allergy Test w/ Candida
IgG Asian Food Allergy Test
Kryptopyrrole Test
Metals Fecal Test
Metals Hair Test
Metals Red Blood Cell Test
Metals Urine Test
Metals Whole Blood Test

Phospholipase A2 Activity Test


OAT + IgG Food Allergy Test
w/ Candida Combo
Vitamin D Test

(F) Estimated Cost:

$699.00
$99.00

WHAT YOU NEED TO DO NOW:

Read this notice, so you can make an informed decision about your care.
Ask us any questions that you may have after you finish reading.
Choose an option below about whether to receive the tests listed above in section (D).
Note: If you choose Option 1 or 2, we may help you to use any other insurance that you might have, but Medicare
cannot require us to do this.

(G) OPTIONS: Check only one box. We cannot choose a box for you.
OPTION 1. I want the tests listed above. You may ask to be paid now, but I also want Medicare billed for an official
decision on payment, which is sent to me on a Medicare Summary Notice (MSN). I understand that if Medicare doesnt pay, I
am responsible for payment, but I can appeal to Medicare by following the directions on the MSN. If Medicare does pay,
you will refund any payments I made to you, less co-pays or deductibles.
OPTION 2. I want the tests listed above, but do not bill Medicare. You may ask to be paid now as I am responsible for
payment. I cannot appeal if Medicare is not billed.
OPTION 3. I dont want the tests listed above. I understand with this choice I am not responsible for payment, and I
cannot appeal to see if Medicare would pay.

(H) Additional Information:


This notice gives our opinion, not an official Medicare decision. If you have other questions on this notice or
Medicare billing, call 1-800-MEDICARE (1-800-633-4227/TTY: 1-877-486-2048).
Signing below means that you have received and understand this notice. You also receive a copy.

(I) Signature:

(J) Date:

According to the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it displays a valid OMB control
number. The valid OMB control number for this information collection is 0938-0566. The time required to complete this information collection is estimated
to average 7 minutes per response, including the time to review instructions, search existing data resources, gather the data needed, and complete and
review the information collection. If you have comments concerning the accuracy of the time estimate or suggestions for improving this form, please write
to: CMS, 7500 Security Boulevard, Attn: PRA Reports Clearance Officer, Baltimore, Maryland 21244-1850.

Form CMS-R-131 (03/08)

Page 5 of 5

Form Approved OMB No. 0938-0

Revised 07/10/15

Nutritional Supplements

Nutritional
Supplements

Nutritional Supplements

ORDER

Distributor
Prices

Product

PACKAGES
Code

Description

Nutritional Support Starter Package


(BNP, CLMG, CLOL, ANTX & ZNCP-180)
Syndion Nutritional Support Starter
Package (SYND-P, CLOL & CLMG)
Yeast Control Package - Liquid
(GLDN-L, UVA-L, BWAL, & ALL-L)

NSSP
SNSP
YCPL

ANTIOXIDANTS (cont)

Amt.

Retail Distrib. Qty.


Price
Price

1 pack

$133.00

$93.10

1 pack

$123.00

$86.10

1 pack

$85.00

$59.50

MULTI-VITAMINS
BNP
DRES
ONE-30
SYND-C
SYND-P
SSM-U
SSV

Basic Nutrients Plus


Daily Resource
One n Only
Syndion Capsules
NEW!
Syndion Powder
BrainChild S.S. II Minerals - Unflavored
BrainChild S.S. II Vitamins - Lemon Lime

BCOM
BIOT
FOLN
MFOL
NIAC-100
NIAC-500
P5PM
VB1
VB12-L
VB6
VITA
VITC
VITC-C
VITC-T
VITD-L
VITD
VITE
VITE-L
VITK-60

B-Complex
Biotin 1000 mcg
Folinic Acid 400 mcg
Methyl-Folate 1000 mcg
Niacin, 100 mg
Niacinamide 500 mg
P-5-P with Magnesium
Vitamin B1 Thiamine 100 mg
Methyl-Mate - Liquid Methylcobalamin
Vitamin B6, 50 mg
Micellized Vitamin A 5025 IU
Vitamin C Chewable 250 mg
Buffered Vitamin C
Vitamin C Powder from Tapioca
Micellized Vitamin D 1000 IU
Vitamin D 1000 IU
Vitamin E 400 IU
Aqua-E Vitamin E
Vitamin K2 (Menatetrenone) 5 mg

CALC-180
CALI
CAL-P
CLMG
CLMG-C
CMTE
CPRI
IODC
IRNI
LITH
LITH-60
MAGC-120
MAG-P
MAGI
MLBDI
POTI
SLNM
SELL
ZNCR
ZNCI
ZNCP
ZNCP-180

Chelated Calcium
Liquid Calcium - Ionic
Calcium Citrate Powder
Calcium Chewable w/Magnesium
Cal/Mag Citrate
Chelate-Mate - Ionic
Liquid Copper - Ionic
Iodine Complex, 6.25
Liquid Iron - Ionic
Liquid Lithium - Ionic
Lithium Orotate
Chelated Magnesium 235 mg
Magnesium Citrate Powder
Liquid Magnesium - Ionic
Liquid Molybdenum - Ionic
Liquid Potassium - Ionic
Chelated Selenium 250 mg
Selenium Liquid 250 mcg
Chelated Zinc 50 mg
Liquid Zinc - Ionic
Zinc Picolinate 50 mg
Zinc Picolinate 25 mg

180 caps
240 caps
30 caps
180 caps
188 g
32 oz
32 oz

$26.00
$44.00
$15.00
$59.00
$69.00
$54.50
$54.50

$18.20
$30.80
$10.50
$41.30
$48.30
$54.50
$54.50

$19.00
$10.00
$13.00
$27.00
$6.00
$9.00
$22.00
$5.00
$35.00
$8.00
$18.00
$7.00
$22.00
$30.00
$21.00
$8.00
$22.00
$40.00
$21.00

$13.30
$7.00
$9.10
$18.90
$4.20
$6.30
$15.40
$3.50
$21.00
$5.60
$12.60
$4.90
$15.40
$21.00
$14.70
$5.60
$15.40
$28.70
$14.70

$29.00
$29.00
$18.00
$29.00
$22.00
$43.00
$20.00
$14.00
$20.00
$26.00
$21.00
$24.00
$27.00
$29.00
$20.00
$20.00
$12.00
$13.00
$14.00
$21.00
$13.00
$18.00

$20.30
$20.30
$12.60
$20.30
$15.40
$30.10
$14.00
$9.80
$14.00
$18.20
$14.70
$16.80
$18.90
$20.30
$14.00
$14.00
$8.40
$9.10
$9.80
$14.70
$9.10
$12.60

VITAMINS
90 caps
100 tabs
120 caps
120 caps
100 tabs
100 caps
100 caps
100 tabs
30 ml
100 tabs
1 fl. oz
100 tabs
180 caps
150 g
1 fl. oz
100 soft gels
100 soft gels
8 fl. oz
60 caps

MINERALS
180 caps
16 fl oz
300 g
250 tabs
250 caps
16 fl oz
50 ml
90 caps
50 ml
50 ml
60 caps
120 caps
300 g
16 fl oz
50 ml
50 ml
90 caps
2 fl oz
60 caps
50 ml
60 caps
180 caps

ANTIOXIDANTS
ANTX
COEQ
GLUT
LGSH-L

Antioxidant Formula
Coenzyme Q-10 25 mg w/L-Taurine
L-Glutathione 75 mg
Essential GSH-Liposomal Glutathione

Mental Health Support =

7797 Quivira Road,

180 caps
60 caps
60 caps
4 fl oz

$35.00
$21.00
$20.00
$60.00

$24.50
$14.70
$14.00
$42.00

Total

Code

Description

Amt.

NAC
NADH
PYC-120
UBIQ

N-Acetyl Cysteine 500 mg


NADH 5 mg
Pycnogenol 25 mg
Ubiquinol 100 mg

5HTP
ALC
CAR
CARN
GABA
GLTM
GLY
LYS
SAMe
TAUR
TYRO

5 HTP 50 mg
Acetyl-L-Carnitine 500 mg
L-Carnitine 250 mg
L-Carnosine 500 mg
GABA 500 mg
L-Glutamine 500 mg
Glycine 500 mg
L-Lysine 500 mg
SAMe 200 mg (Physician Referred)
L-Taurine 500 mg
Tyrosine 500 mg

BALP
CLOC
CLOC-L
CLOL
CLOL-NLM
CLOL-S
EPO
UO3-120
VFFO-L

Balance Plus
Carlson's Cod Liver Oil 1000 mg
Carlson's Cod Liver Oil 1000 mg
Carlsons Cod Liver Oil (lemon flavored)
Carlsons Cod Liver Oil (unflavored)
Nordic Naturals Cod Liver Oil (strawberry)
Evening Primrose Oil
Ultra Omega-3 Fish Oil
Carlson's Very Finest Fish Oil

CLTR
PROB-60
PROB
SBC
PBP
THBC
THBD
THER
VSL3-C

Culturelle 10 billion cells


30 caps
Probiotic Support Formula
60 caps
Probiotic Support Formula
30 caps
Saccharomyces Boulardii
50 caps
NEW! 15 packets
Pro-Bio Premium
Ther-Biotic Complete (Physician Referred)
60 caps
Ther-Biotic Detox Support(Phys. Referred) 60caps
Theralac
30 caps
VSL#3 Capsules
60 caps

CNDX-120
DIZ-100
INT-120
INTP-120
NFEN

ZYME-CHEW

Candex
DiZorb
NEW!
Interfase (Physician Referred)
Interfase Plus (Physician Referred)
Houstons No-Fenol
Houstons No-Fenol Chewable
Houstons AFP Peptizyde
Houstons AFP Peptizyde Chewable
Houstons TriEnza
Houstons TriEnza Chewable
Houstons Zyme Prime
Houstons Zyme Prime Chewable

AIF-120
AIF-CHEW
MLRN
MIMM

A & I Formula
A & I Formula Chewable
Monolaurin 600 mg
Transfer Fact. Multi-Immune (Phys. Ref.)

ALL-C
ALL-L
ARCH
BWAL
CDF
CYF
CURC

Allimax Allicin Capsules


Allimax Liquid
Artichoke Extract
Black Walnut Extract Liquid
Candida Defense Formula
Candida Yeast Formula
Curcumin 250

60 caps
60 tabs
120 caps
60 soft gels

Retail Distrib. Qty.


Price
Price

$22.00
$30.00
$38.00
$58.00

$15.40
$21.00
$26.60
$40.60

$20.00
$30.00
$17.00
$21.00
$15.00
$9.00
$12.00
$12.00
$48.00
$12.00
$16.00

$14.00
$21.00
$11.90
$14.70
$10.50
$6.30
$8.40
$8.40
$33.60
$8.40
$11.20

$21.00
$14.00
$20.00
$35.00
$35.00
$24.00
$19.00
$37.00
$35.00

$14.70
$9.80
$14.00
$24.50
$24.50
$16.80
$13.30
$25.90
$24.50

$22.00
$47.00
$26.00
$21.00
$52.00
$43.00
$52.00
$45.00
$48.00

$17.60
$32.90
$18.20
$14.70
$36.40
$30.10
$36.40
$31.50
$42.00

$49.00
$16.00
$48.00
$32.00
$25.00
$38.00
$25.00
$38.00
$48.00
$44.00
$24.00
$38.00

$34.30
$11.20
$33.60
$22.40
$17.50
$26.60
$17.50
$26.60
$33.60
$30.80
$16.80
$26.60

$34.00
$15.00
$33.00
$45.00

$23.80
$10.50
$23.10
$31.50

$33.00
$33.00
$13.00
$20.00
$29.00
$25.00
$24.00

$23.10
$23.10
$9.10
$14.00
$20.30
$17.50
$16.80

Total

AMINO ACIDS
100 caps
60 caps
60 caps
30 caps
60 caps
60 caps
100 caps
100 caps
60 tabs
100 caps
100 caps

ESSENTIAL FATTY ACIDS


90 soft gels
100 soft gels
250 soft gels
500 ml
500 ml
8 fl. oz
100 soft gels
120 soft gels
500 ml

PROBIOTICS

ENZYMES

NFEN-CHEW

PEPT-AFP

PEPT-CHEW

TRI-180
TRI-CHEW
ZYME

120 caps
100 caps
120 caps
120 caps
90 caps
180 tabs
90 caps
180 tabs
180 caps
180 tabs
90 caps
180 tabs

IMMUNE SUPPORT
120 caps
60 tabs
90 caps
60 caps

BOTANICAL EXTRACTS
NEW!

NEW!

Lenexa, KS 66215 Phone: (913) 754-0458 Fax: (913) 248-7609


Web: www.nbnus.com
E-mail: info@nbnus.com

30 caps
10 ml
60 caps
1 fl oz
90 caps
2 oz
100 caps

Toll Free: 1-877-575-2467

Nutritional Supplements

ORDER

Distributor
Prices

Product

BOTANICAL EXTRACTS (cont)


Code

Description

Amt.

GLDN
GLDN-L
GSE-L
MCT
MILT
OLXT
ORGL
PARA
SMTO-L
THEA
UVA
UVA-L

Goldenseal Extract 125 mg


Goldenseal Extract Liquid
Grapefruit Seed Extract Liquid
M.C.T. Liquid
Milk Thistle 200 mg
Olive Leaf Extract 500 mg
Oreganol P73
Parasite Formula
Samento (Cat's Claw)
L-Theanine 100 mg
Uva Ursi 250 mg
Uva Ursi Extract Liquid

AKG
CHAR
CHOL
DMG
ESC
INOS
MAL
MELA-60
TMG
TRUF

Alpha-Ketoglutaric Acid
Activated Charcoal
Sonic Cholesterol (Physician Referred)
DMG-125 mg (Dimethylglysine)
Epsom Salts Cream
Inositol Powder
Malic Acid 500 mg
Melatonin 1 mg
TMG Powder (Trimethylglycine)
TruFiber Powder

Retail Distrib. Qty.


Price
Price

30 caps
1 fl. oz
2 fl. oz
8 fl. oz
60 caps
60 caps
60 soft gels
2 fl. oz
30 ml
60 caps
60 caps
1 fl. oz

$17.00
$20.00
$12.50
$14.00
$20.00
$17.00
$31.00
$25.00
$48.00
$19.00
$13.00
$20.00

$11.90
$14.00
$8.75
$9.80
$14.00
$11.90
$21.70
$17.50
$33.60
$13.30
$9.10
$14.00

$16.00
$10.00
$32.00
$26.00
$15.00
$34.00
$12.00
$7.00
$12.00
$33.00

$11.20
$7.00
$19.20
$18.20
$10.50
$23.80
$8.40
$4.90
$8.40
$23.10

SPECIALTY PRODUCTS
60 caps
90 caps
120 caps
100 tabs
2 oz
10 oz
100 caps
60 tabs
60 g
6.2 oz

DETOXIFICATION
Bio-Chelat

BIOC

100 ml
45 caps
120 caps
30 supp

DMSA-100 DMSA 100 mg (Physician Referred)


DMSA-25 DMSA 25 mg (Physician Referred)

DTXM

Detoxamin 750 mg

COCO
DARI
DARI-C
EGPZ
KCSC
PBPE
RPP
XGMP
XGMS
XYKT
XYLI
XYSM

Coconut Oil
DariFree Potato Milk
DariFree Chocolate Potato Milk
Ener-G Foods Wylde Pretzels
KinniTOOs Choc. Sand. Cremes Cookies
Gorge Delights Pear Bar
Rice Protein Plain
Spry Peppermint Gum w/ Xylitol
Spry Spearmint Gum w/ Xylitol
Sugar Free Ketchup
Smart Sweet XYLITOL
Sugar Free Maple Syrup

$39.00 $27.30
$41.00 $28.70
$32.00 $22.40
$240.00 $168.00

FOOD / COOKING
32 oz
Makes 6 qts
Makes 5 qts
8 oz
8 oz
40 g
21 oz
10 pc. pack
10 pc. pack
10 oz
1.5 lbs
8.5 oz

$18.00
$12.00
$12.00
$4.00
$6.00
$1.75
$18.00
$1.25
$1.25
$6.00
$14.00
$6.00

$14.40
$10.60
$10.60
$3.20
$4.80
$1.40
$14.40
$1.00
$1.00
$4.80
$11.20
$4.80

PERSONAL CARE
DEOC
DEOL
DEOU
ECO
REPL
XNSL
XTHP
XTHP-BGUM

T. Naturals Deodorant Stick - Citrus Sport


T. Naturals Deodorant Stick - Lavender
T. Naturals Deodorant Stick - Unscented
eco All-Natural Body Sunscreen
All Natural Bug Repellent
Spry Nasal Wash
Spry Toothpaste Tube w/ Xylitol
Branam Kids Bubblegum Toothpaste

55 g
55 g
55 g
3.5 oz
4 oz
1.5 oz
4 oz
5 oz

$6.00
$6.00
$6.00
$17.00
$12.00
$8.00
$5.50
$7.00

$4.80
$4.80
$4.80
$13.60
$9.60
$6.40
$4.40
$6.50
SUBTOTAL

TAX (8.9% for KS residents only)


DISCOUNT (when applies)
SHIPPING
TOTAL

Total

Ordered by:
First Name:

Middle Name:

Last Name:

Address:

State / Province:

City:
Zip/Postal Code:

Country:
Fax:

Phone:
E-Mail:

Ship to (if different):


First Name:

Middle Name:

Last Name:

Address:

State / Province:

City:
Zip/Postal Code:

Country:
Fax:

Phone:
E-Mail:

Notes:

Payment Method
Amount To Be Charged:
Money order

$
Check*

Credit Card (check one)

*Make checks payable to New Beginnings Nutritionals. 7797 Quivira Rd., Lenexa, KS 66216

MasterCard

Visa

American Express

Discover

Account #
Name as it appears on card:

Exp. Date

Card Code

Unopened products may be returned within 30 days of purchase.


Shipping charge will not be refunded and all returned items are subject
to a 10% restocking fee. Items cannot be returned after 30 days from
the date of purchase. Probiotics may not be returned for any reason.

6/15/12

Quality Gluten/Casein Free Nutritional Supplements


7797 Quivira Road,

Lenexa, KS 66215 Phone: (913) 754-0458 Fax: (913) 248-7609


Web: www.nbnus.com
E-mail: info@nbnus.com

Nutritional Supplements

Toll Free: 1-877-575-2467

Helping Children, Adults, and Families Make a Difference

Nutritional Supplements

New Beginnings Nutritionals


7797 Quivira Road, Lenexa, KS 66215 Phone: (913) 754-0458 Fax: (913) 248-7609

Toll Free: 1-877-575-2467

Nutritional Supplements

New Beginnings Nutritionals

Introduction to Integrative Medicine for Mental Health

Introduction to
Integrative Medicine
for Mental Health

Introduction to Integrative Medicine for Mental Health

Introduction to Integrative Medicine for Mental Health


The Integrative Medicine approach to treating mental health disorders utilizes multiple fields of
medicine, nutritional sciences and biochemistry. This approach is supported by peer reviewed
studies and successful clinical practice.
Integrative Medicine for Mental Health (IMMH) seeks to improve the health and well-being of
those affected with mental health disorders by recognizing that individual biochemistry plays a
significant role in the way a patient responds to treatment. Traditional and specialized
laboratory testing provide a roadmap to identify underlying causes and guide treatment to
relieve symptoms.
It is important to recognize that seemingly unrelated health issues can profoundly affect mental
functioning. For example under-functioning thyroid, hormonal imbalances, nutritional
deficiencies, food and environmental allergies, chemical sensitivities, infections, and exposure
to environmental toxins all can influence mental health.
Linus Pauling coined the term Orthomolecular Medicine as a treatment for disease and in
particular, mental health. Traditional psychiatric and behavioral therapies can be greatly
enhanced by understanding the bodys unique biochemistry and incorporating the right
nutrients, in the proper amounts and form to support systemic functions. Molecules that support
optimal mental functioning include vitamins, minerals, trace minerals, amino acids, essential
fatty acids, enzymes and more.
In previous generations, our foods contained much higher concentrations of nutrients than
todays food sources. Mega-farming, fast food, immune system dysfunction, exposure to
infectious conditions and the daily exposure to thousands of environmental chemicals all
contribute to imbalanced brain chemistry. Our cultural climate of fast-paced, high stress and
sedentary lifestyles greatly influences the prevalence of mental health disorders.
The zeebra formulations supplement line has been designed to meet the unique needs of
individuals who suffer from a variety of mental health related disorders and is exclusively
available through New Beginnings Nutritionals www.nbnus.com.
The goal of this program is to advance the knowledge and improve the practice and treatment of
mental health disorders by providing support to the mental health practitioner. IMMH offers a
wealth of knowledge on research-based therapies through conferences, workshops, webinars,
newsletters and other web-based resources. For updates, news and to contribute content
please visit www.immh.org.

Website: www.immh.org
E-mail: info@integrativemedicineformentalhealth.com

Introduction to Integrative Medicine for Mental Health

Website: www.immh.org
This website provides important information and resources for you and for patients seeking
IMMH trained practitioners.
The following is available on the website:
Clinician Registry
IMMH Clinician Manual
Password protected for Great Plains Laboratory clients only.
Contact your account representative for more information.
Upcoming Conferences and Workshops
Recorded Webinars
Books and DVDs
Scientific Research and Articles
Newsletter Sign-Up
Other Resources

Introduction to Integrative Medicine for Mental Health

Recommended Testing for Mental Health Patients


Through The Great Plains Laboratory, Inc.
Comprehensive Mental Health Panel
Advanced Cholesterol Profile
Amino Acids Urine Test
Comprehensive Fatty Acids Test
Comprehensive Stool Analysis
Copper/Zinc Profile
Gluten/Casein Peptides Test
IgG Food Allergy Test w/ Candida
Metals Hair Test
Organic Acids Test
Vitamin D Test

Basic Mental Health Panel


Amino Acids Urine Test
Comprehensive Fatty Acids Test
Gluten/Casein Peptides Test
IgG Food Allergy Test w/ Candida
Metals Hair Test
Organic Acids Test

Other GPL Testing


Celiac Disease Test
IgE Food & Inhalant Allergy Tests
Metals Hair, Urine & Stool Tests
Streptococcus Antibodies Profile
Uric Acid Test
Testing to Consider Through Traditional Labs*
Complete Blood Count (CBC) Test
Comprehensive Chemistry Panel
Dehydroepiandrosterone-Sulfate (DHEA-S) Test
Ferritin Test
Thyroid Panel (TSH, T3, T4)
*Unlike comprehensive biomedical testing, routine lab work often fails to
uncover subtle abnormalities which can have a profound effect on health.

Introduction to Integrative Medicine for Mental Health

New Beginnings Nutritionals


7797 Quivira Road
Lenexa, KS 66216
Phone: (913) 754-0458
Fax: (913) 248-7609
Toll Free: (877) 575-2467
E-mail: info@nbnus.com

Whatarezeebraformulationsallabout?
ZeebraformulationsisanewproductlinebeingdistributedexclusivelybyNewBeginningsNutritionals.This
productlineisdesignedtomeettheuniqueneedsofindividualswhosufferfromavarietyofmentalhealth
relateddisordersincludingdepression,anxiety,bipolar,OCD,eatingdisorders,etc.Thesenewproductsand
formulationsaremadeavailableunderthecarefuldirectionofDr.JamesGreenblatt,achildandadult
psychiatristwhohasbeensuccessfullytreatingpatientswithmentalhealthdisordersforover20yearsusing
anintegrativemedicalapproach

WhoisDr.JamesGreenblatt?
JamesM.Greenblatt,M.D.isaduallyboardcertifiedchildandadultpsychiatristandistheFounderand
MedicalDirectorofComprehensivePsychiatricResources(CPR),anintegrativepsychiatrypractice.Dr.
GreenblattreceivedhismedicaldegreeandcompletedhisadultpsychiatryresidencyatGeorgeWashington
UniversityinWashingtonD.C.,andcompletedafellowshipinchildandadolescentpsychiatryatJohnsHopkins
MedicalSchool.Dr.GreenblattisanAssistantClinicalProfessoratTuftsUniversityMedicalSchool,
DepartmentofPsychiatry.Forover20years,Dr.GreenblatthasbeenaleaderinIntegrativeMedicine,
lecturingthroughoutNorthAmericaonthescientificevidencefornutritionaltreatmentsinpsychiatryand
eatingdisorders.Dr.GreenblattnowservesasMedicalConsultantforMentalHeathDisordersforNew
BeginningsNutritionals.Inhissuccessfulpractice,Dr.Greenblattincorporatesspecializedlaboratorytesting,
dietarychanges,nutritionalsupplementsandotherbiomedicaltherapieswithtraditionaltreatmentsand
therapiestoimprovethetreatmentoutcomesofhispatients.

Whatdoesthenamezeebramean?
ThewordzeebraismnemoniccreatedfromDr.Greenblattsworkondepressionwhichemphasizesthat
everyaspectofapersonmind,bodyandspiritneedstobeinvestigated.Themostcriticalconceptto
understandisthatjustasthestripepatternoneveryzebraiscompletelyunique,eachindividualalsohasa
completelyuniquebiochemistrythatneedstobeexploredthroughtestingbeforeeffectivetreatmentscanbe
applied.Withmentalhealthdisorders,justasinautism,aonesizefitsallapproachisnoteffective.

Introduction to Integrative Medicine for Mental Health

Whatzeebraproductsareavailablenow?
BalancePlus(Omega3,6,and9s)

DailyResource(wholefoodbasedmultivitamin)
DiZorb(HClandpepsindigestiveenzyme)

IodineComplex(IodineandIodide)

ZincSync(zincsufficiencytastetest)

MethylFolate
Niacin100mg
Niacinamide500mg
LTyrosine500mg
LithiumOrotate

Arethesetheonlyproductshelpfulformentalhealthdisorders?
No.ManyotherproductswithintheNewBeginningsproductlinecanbeeffectivelyusedtosupporthealthy
mentalfunctioning.VisittheMentalHealthSupportproductcategoryfromthehomepageoftheNew
BeginningsNutritionalswebsiteforcomprehensivelistofsupportingproducts.

Aretheseproductsgoodfortheautismpopulationaswell?
WiththeexceptionoftheDailyResourceMultivitamin,whichcontainscopper,zeebraproductscanbeused
forindividualswithautismbecausetheycontainthesamepurityandhighstandardsthatarefoundintheNew
Beginningsproductline.Itisrecommendedthatyoufirstseektherecommendationofyourhealthcare
practitionerforappropriateproductanddosagerecommendations.

HowdoIlearnmoreaboutintegrativemedicinefortreatingmentalhealth
disorders?
Visitwww.IMMH.organdsignuptoreceiveafreeenewsletterthatwillincludevitalinformation(upcoming
conferences,freewebinars,research,etc.)relatedtomentalhealthissues.

Introduction to Integrative Medicine for Mental Health

New Beginnings Nutritionals

7797 Quivira Road, Lenexa, KS 66216


Contact us for product information, pricing and support
Web: www.nbnus.com E-mail: info@nbnus.com
Toll Free: 877-575-2467

Practitioner Supplement Recommendations


Physician Information:
Patient
Date

Date:

__________________________
Name: __________________________
of Birth: __________ Weight: _________

Zeebra Formulations
_____Daily Resource 4 capsules, 2x daily with food
_____ Methyl-Folate 2 capsules daily with food
_____ Niacin, 100 mg 1-3 tablets daily
_____ Niacinamide 500 mg 1-4 capsules daily
_____ Iodine Complex 1 capsule daily with food
_____ Lithium Orotate 1 capsule daily with food
_____ ZincSync Read recommended use in catalog or at www.nbnus.com
_____ Tyrosine 1-4 capsules daily, between meals
_____ Balance Plus 3 capsules daily with food
_____ DiZorb 1-2 capsules after start of meal, do not take on empty stomach
Related Products
_____ Methyl-Mate/ Methylcobalamin 5 drops daily, hold under tongue 1 min. before swallowing
_____ Buffered Vitamin C 2 or more capsules daily
_____ Mycellized Vitamin D 5 drops per day
_____ Vitamin D 1000 IU 2-5 soft gels daily with meals
_____ Liquid Lithium- Ionic Adults: 10 drops daily with food; Children: 3-5 drops daily with food
_____ Chelated Magnesium 1-2 capsules, 2x daily with or without food
_____ Magnesium Citrate Powder 1 scoop, 3x daily with meals
_____ Liquid Magnesium- Ionic 1.5 tsp in juice, 2x daily
_____ Liquid Zinc 10 drops daily with food, take separate from calcium
_____ Zinc Picolinate 50 mg 1 capsule daily, taken separate from calcium
_____ Zinc Picolinate 25 mg 1-2 capsules daily, taken separate from calcium
_____ L-Glutathione 1-2 caps daily
_____ 5 HTP 1-2 caps daily between meals
_____ GABA 1-4 capsule daily
_____ L-Glutamine 1-2 capsules daily
_____ Glycine 1-2 capsules daily with food
_____ L-Taurine 1-2 capsules daily
_____ Evening Primrose Oil 1 gelcap daily with food
_____ Ultra Omega-3 Fish Oil 1-2 gelcaps daily with food
_____ Very Finest Fish Oil 1-2 tsp daily with food
_____ Houstons AFP Peptizyde Capsules 1-2 capsules before eating, not to exceed 9 daily
_____ Houstons TriEnza Capsules 2 capsules with or just before each meal
_____ Epsom Salts Cream 1 or more grams to fatty areas, 2x daily
_____ Inositol Powder -1 tsp daily
_____ Melatonin 1 mg 2-4 tablets, 30 minutes prior to bedtime
_____ Other _____________________________________________
_____ Other _____________________________________________

Introduction to Integrative Medicine for Mental Health

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