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BIBLIOTHERAPY
AND MINDFULNESS:
1#
PILOT TRIAL
Amit Sood, MD, Kavita Prasad, MD,1 Laura Loehrer, 1 Darrell Schroeder, MS,2
and Bauer Brent, MD1
INTRODUCTION
Stress is a ubiquitous problem that is associated with many
acute and chronic medical conditions such as cardiac arrhythmia,1,2 cardiovascular disease,36 impaired immune function,68
and peptic ulcer disease.9 In moderation, stress is healthily
tolerated; excessive stress, however, is associated with poor
medical outcomes,6 unhealthy coping mechanisms,1012 and
symptoms of anxiety and depression.6,13,14 Stressors are difcult
to remove. However, one can enhance one's ability to handle
stress, an attribute often called resiliency.
Stress Management and Resiliency Training (SMART) was
developed as a structured and simple program at Mayo
Clinic, Rochester to decrease personal stress and enhance
resiliency (A.S.V. Sood, D.R. Schroeder, B. Gorman, stress
management and resiliency training (SMART) program
among Department of Radiology faculty: a pilot randomized
clinical trial, unpublished).15,16 SMART is an abbreviated
248
version of a therapy developed called Attention and Interpretation Therapy (AIT). AIT and SMART focus on two
aspects of human experience: attention and interpretation.
Human attention tends to focus upon threats.17 These
threats, in modern times, may take the form of hurts,
regrets, worries, and fears that can draw our attention away
from the present moment and into the domains of the past
and the future. This can lead to ruminative thinking,
avoidance, and ineffective thought suppression.18,19 Consequently, untrained attention leads to an increase in perceived
stress. SMART teaches learners to focus their attention in the
present moment and to defer unrened judgments. Learners
are also taught to cultivate and guide their interpretations by
higher-order principles such as forgiveness, acceptance, gratitude, compassion, and life's meaning, instead of supercial
prejudices.
Traditionally, an instructor administers the SMART program to participants in an individual or group session. Three
studies have been completed, which have demonstrated the
feasibility and effectiveness of this program (A.S.V. Sood, D.
R. Schroeder, B. Gorman, stress management and resiliency
training (SMART) program among Department of Radiology
faculty: a pilot randomized clinical trial, unpublished).15,16
Subjects demonstrated signicant reductions in perceived
stress and anxiety, and increases in resilience, mindful
attention, and overall quality of life.15,16
(MAAS). The participants completed these web-based baseline surveys during the initial meeting with the study
coordinator or shortly after on their own time. At the end
of the 12 weeks, the web-based surveys were mailed to
participants for completion.
The CD-RISC is a 25-item scale with each of the item rated
on a 04 scale, with higher scores reecting greater resilience.30 CD-RISC has been evaluated for reliability, validity,
and factor structure and has been shown to have good
psychometric properties with the ability to distinguish
between participants with lesser and greater resilience.30,49
PSS is an adequately reliable 14-item self-report tool that
provides a global measure of perceived stress.31 Responses
range on a 5-point scale from never to very often. A higher
score indicates greater stress. The PSS correlates well with
measures of stress from life events and social anxiety. LASA
has respondents rate ve single items on a scale of 010.32
It evaluates overall quality of life, overall mental, physical,
emotional, social, and spiritual well-being.32 The Smith
Anxiety Scale (SAS) is a 22-item self-report tool that differentiates between cognitive and somatic anxiety symptoms,
which are similar to most stress symptoms.3335 Responses
range from 0 as bad as it can be to 10 as good as it can be.
MAAS is a 15-item measure that assesses the frequency of
mindful states in day-to-day life, using both general and
situation-specic statements.36
Study Intervention
For the study intervention, participants were given the book,
Train Your Brain Engage Your Heart Transform Your Life
along with three handouts that summarized the contents of
the book. The 443-page book presents the contents of the
SMART program in 13 sections (Table 1). The book has 523
references to peer-reviewed articles.
Table 1. Train Your Brain Engage Your Heart Transform Your Life
Section I
Section II
Section III
Section IV
Section V
Section VI
Section VII
Section VIII
Section IX
Section X
Section XI
Section XII
Section XIII
Appendices
Content summary
Education on neuropsychology related
to stress and resilience
Overview of the SMART program
Concepts and skills of attention training
Concepts related to interpretations
Gratitude
Compassion
Acceptance
Meaning and purpose
Forgiveness
Relationship skills
Meditation and prayer
Growth and transformation
IIV Instruction in relaxation using breath
and body as anchor, physical exercise,
diet, and other tips from the SMART program
Table 2. Demographicsa
Characteristic
Age (years)
Gender
Male
Female
a
b
SMART (n 33 )
b
48.1 11.5
5 (15%)
28 (85%)
Statistical Analyses
Study endpoints included changes in resilience (CD-RISC),
stress (PSS), anxiety (SAS), overall quality of life (LASA), and
mindful attention (MAAS). These assessments were evaluated
at baseline and at week 12. Data were summarized as both raw
scores and also as changes from baseline. Measurements were
compared to baseline using the paired t-test. A sample size of
n 40 was originally selected for this pilot study after
weighing statistical considerations along with logistical and
resource constraints. In general, for a paired t-test a sample
size of n 40 provides statistical power (two-tailed, 0.05)
of 87% to detect a change (pre versus post) of 0.5 standard
deviation units.
RESULTS
Demographics
All participants were employees of Mayo Clinic. Of the 90
respondents, 37 fullled the enrollment criteria: 12 nurses,
three physicians, and the rest allied health staff (four physical/
occupational therapists, two unit secretaries, one P.A.-C, one
audiologist, and 14 others). There were four dropouts, leaving
33 participants who completed the study. The majority of the
study participants were women (85%), with the mean age of
48.1 years (Table 2).
Study Outcomes
Measure of resilience (CD-RISC) increased signicantly from
73.4 10.8 at baseline to 81.8 13.8 at the end of the 12week period in participants (P o .001). Perceived stress (PSS)
decreased signicantly from 25.7 5.6 initially to 19.5
7.3 after 12 weeks (P o .001). Measures of anxiety (SAS)
decreased from 55.5 15.4 at baseline to 41.7 14.9 in
participants (P o .001). Mindful attention (MAAS) increased
from 3.7 0.7 at baseline to 4.3 0.9 after 12 weeks (P
.001). Overall, quality of life (LASA) increased from 7.0
DISCUSSION
This pilot study demonstrates that a self-directed stress
management program using only bibliotherapy for decreasing
perceived stress and enhancing resilience is feasible. The study
also suggests that the intervention has the potential to
improve resiliency, stress, anxiety, quality of life, and mindful
attention. The brief duration and self-directed aspect of the
training are particularly appealing characteristics of the
intervention.
Stressors are a common presence in the lives of many
people. Small amounts of perceived stress can be healthily
tolerated by individuals. However, when stress becomes
prolonged, repetitive, and intense, it may lead to health
problems ranging from cardiovascular disease36 to depression.6,13,14 The expectations of modern society often make it
difcult to reduce the stressors that individuals face on a dayto-day basis. However, we can enhance the ability of
individuals to cope with that stress or their resiliency. By
enhancing resiliency, we are able to reduce perceived stress
and its accompanying anxiety.15,16
A self-directed SMART program has the potential to
reduce stress and increase resiliency in a large number of
people. Several other resiliency training programs have demonstrated positive results in randomized controlled trials.37,38
However, many of these programs require several sessions of
in-person instruction sometimes lasting several weeks.20
26,39,40
This can be expensive and a time commitment that
is difcult for many people to make. Several randomized
control trials of SMART in-person training have been conducted as well. These trials have shown similar effectiveness
for stress reduction and resiliency training in one or more inperson sessions followed by self-directed practice (A.S.V.
Sood, D.R. Schroeder, B. Gorman. Stress management and
resiliency training (SMART) program among Department of
Radiology faculty: a pilot randomized clinical trial, unpublished).15,16 This result is consistent with a meta-analysis that
found guided self-help comparable in reducing anxiety and
depression as face-to-face therapy.29 Observing similar
effectiveness with bibliotherapy as we did with in-person
training is encouraging for our ability to more broadly scale
the program.
Our results are also consistent with several other studies
and meta-analyses that have found bibliotherapy effective in
the treatment of stress,4143 anxiety,28,29,41,43 well-being,43 and
Table 3. Outcome Measures at Baseline and Week 12 Among Those Who Completed the Study (n 33)a
Scale
Connor Davis Resilience Scale
Mindful Attention Awareness Scale
Perceived Stress Scale
Smith Anxiety Scale
Overall quality of life
a
Baseline
73.4
3.7
25.7
55.5
7.0
10.8
0.7
5.6
15.4
1.7
Week 12
o.001
o.001
o.001
o.001
.001
81.8
4.3
19.5
41.7
8.0
13.8
0.9
7.3
14.9
1.5
Scores at baseline and week 12 are summarized using mean SD. Changes from baseline to week 12 were assessed using the paired t-test.
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