Effect of Local Infiltration Anesthesia With Ropivacaine on

Postoperative Pain After Hip Hemiarthroplasty

Status: Recruiting
Study Phase: N/A
Start Date: December 2015|Completion Date: December 2017
Condition(s): Femoral Neck Fractures
Full Title of Study
Effect of Local Infiltration Anesthesia With Ropivacaine on Postoperative Pain After
Hip Hemiarthroplasty
Overview
At St.Olavs Hospital each year about 400 patients are treated for femoral neck
fractures, 250 of them receiving hemiarthroplasty. Implementation of fast-track
clinical pathways reduces morbidity and enhances recovery of patients undergoing
hemiarthroplasty. One of the key prerequisites for early rehabilitation is optimized
pain relief. Local infiltration anesthesia with Ropivacaine is part of a multimodal pain
regimen for patients receiving hemiarthroplasty at St.Olavs Hospital, although the
pain reducing effect of local Ropivacaine after hemiarthroplasty has not been
investigated in clinical trials. In this study it will be investigated whether a single shot
with Ropivacaine reduces acute postoperative pain and opioid requirement after
hemiarthroplasty. The findings of this study will have a direct impact on patient
treatment.

Study Details
Study Type: Interventional
Study Design: Allocation: Randomized, Endpoint Classification: Efficacy Study,
Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver,

Investigator, Outcomes Assessor), Primary Purpose: Treatment

Investigator Details
Lead Sponsor: St. Olavs Hospital
Collaborator: Norwegian University of Science and Technology
Study Director: Olav Foss, Phd Ortopedisk forskningssenter, St.Olavs Hospital

Trial Location Details

Facility: Ortopedisk forskningssenter, St.Olavs Hospital Trondheim, Norway

Interventions
Drug: Ropivacaine
Drug: Epinephrine
Drug: Saline

Published Research
Saltvedt I, Prestmo A, Einarsen E, Johnsen LG, Helbostad JL, Sletvold O. Development and delivery of patient treatment in the
Trondheim Hip Fracture Trial. A new geriatric in-hospital pathway for elderly patients with hip fracture. BMC Res Notes. 2012 Jul
16;5:355. doi: 10.1186/1756-0500-5-355.
Hofstad JK, Winther SB, Rian T, Foss OA, Husby OS, Wik TS. Perioperative local infiltration anesthesia with ropivacaine has no effect on
postoperative pain after total hip arthroplasty. Acta Orthop. 2015;86(6):654-8. doi: 10.3109/17453674.2015.1053775. Epub 2015 May
22.

Information Source

ID Number: 2015/1201
NCT Identifier: NCT02585011
Health Authority: Norway:National Committee for Medical and Health Research Ethics
Full Source of Clinical Trial Data: https://clinicaltrials.gov/show/NCT02585011
ClinicalTrials.gov processed this data on May 22, 2016
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