SALT INFORMATION

Amlodipine(5 mg)
MRP:Rs. 25.20 for 1 strip(s) (14 tablet each)
Composition
Amlodipine(5 mg)

Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in chest.

How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces the amount of
calcium that enters the smooth muscles of the blood vessels and heart. As muscle cells require
calcium to contract, reducing the flow of calcium causes the muscle cells to relax and blood
vessels to dilate, reducing blood pressure, force and rate of the heartbeat. It improves blood and
oxygen supply to the heart muscles.

Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness

Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any fixed time
each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision on taking
amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor if it has not
improved.
It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

Pharmacokinetics and pharmacodynamics of amlodipine

Amlodipine is a low-clearance, dihydropyridine calcium antagonist. The slow rate of

elimination (elimination half-life of 40-60 h) confers several pharmacokinetic
characteristics that are not seen with other calcium-antagonist drugs. It has high
oral bioavailability (60-80%) and accumulates to a steady-state with once-daily
administration over a period of 1-1 1/2 weeks. Fluctuation of plasma drug
concentration between doses is between 20 and 25% when once-daily dosing is
used. Onset of effect is gradual after oral administration which is due, in part, to an
intermediate rate of drug absorption (peak plasma drug concentration occurs 6-8 h
after dosing) and perhaps also to the physicochemical characteristics of the drugcell membrane-receptor interaction. The pharmacodynamic profile of the drug in
hypertensive patients is consistent with the disposition of the drug. After single
doses, blood pressure decreases gradually over 4-8 h and may slowly return to
baseline over 24-72 h. No change in heart rate is noted after the dose as the onset
is gradual and physiological reflexes are not activated. During chronic, oral, oncedaily dosing blood pressure is decreased from pretreatment baseline with little
fluctuation over the 24-hour dose interval. Discontinuation of amlodipine treatment
results in a slow return of blood pressure to baseline over 7-10 days, with no
evidence of a 'rebound' effect. Amlodipine is a low-clearance, dihydropyridine
calcium antagonist which is effective for the treatment of hypertension and angina
pectoris with once-daily dosing.

AMLONG 5 MG TABLET
Micro Labs Ltd

MRP:Rs. 49.30 for 1 strip(s) (15 tablet each)

Buy Now

Composition
Amlodipine(5 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.
It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

No AMLODIPINE 5MG TABLET

Jan Aushadhi

MRP:Rs. 3.24 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Amlodipine(5 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not

AMLOPIN 5 MG TABLET
USV Ltd

MRP:Rs. 32.87 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Amlodipine(5 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Expert advice

Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.
It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

AMLOPRES 5 MG TABLET
Cipla Ltd

MRP:Rs. 47.77 for 1 strip(s) (15 tablet each)

Buy Now
Composition
Amlodipine(5 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.
It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

AMLOPIN M 5 MG/50 MG TABLET

USV Ltd

MRP:Rs. 81.50 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Amlodipine(5 mg),Metoprolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Metoprolol(50 mg)
Uses
Metoprolol is a beta-blocker and used to treat high blood pressure, fast and irregular
heartbeat (cardiac arrhythmias especially supraventricular arrhythmia), chest pain
(angina pectoris), overactive thyroid gland (hyperthyroidism), heart failure, early
intervention in heart attack (myocardial infarction) and to prevent migraine attacks.
How it works
It works by relaxing blood vessels and slowing heart rate to improve blood flow and
decrease blood pressure.Early intervention and start of metoprolol in myocardial
infarction reduces infarct size and the incidence of ventricular fibrillation.
Common side effects

Gas or bloating, Depression or dizziness, Nausea, Tiredness, Constipation, Runny nose,

Lightheadedness, Cold hands and feet, A rash or itching on the skin, Vomiting, Rash or itching,
Stomach pain, Heartburn, Dry mouth
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.
It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding

Pharmacokinetics

Absorption
The estimated oral bioavailability of immediate release Metoprolol is about 50% because of presystemic metabolism which is saturable leading to non-proportionate increase in the exposure
with increased dose.
Distribution
Metoprolol is extensively distributed with a reported volume of distribution of 3.2 to 5.6 L/kg.
About 10% of Metoprolol in plasma is bound to serum albumin. Metoprolol is known to cross
the placenta and is found in breast milk. Metoprolol is also known to cross the blood brain
barrier following oral administration and CSF concentrations close to that observed in plasma
have been reported. Metoprolol is not a significant P-glycoprotein substrate.
Metabolism
Metoprolol is primarily metabolized by CYP2D6. Metoprolol is a racemic mixture of R- and Senantiomers, and when administered orally, it exhibits stereoselective metabolism that is
dependent on oxidation phenotype. CYP2D6 is absent (poor metabolizers) in about 8% of
Caucasians and about 2% of most other populations. Poor CYP2D6 metabolizers exhibit severalfold higher plasma concentrations of Metoprolol than extensive metabolizers with normal
CYP2D6 activity thereby decreasing Metoprolols cardioselectivity.
Elimination
Elimination of Metoprolol is mainly by biotransformation in the liver. The mean elimination
half-life of Metoprolol is 3 to 4 hours; in poor CYP2D6 metabolizers the half-life may be 7 to 9
hours. Approximately 95% of the dose can be recovered in urine. In most subjects (extensive
metabolizers), less than 5% of an oral dose and less than 10% of an intravenous dose are
excreted as unchanged drug in the urine. In poor metabolizers, up to 30% or 40% of oral or
intravenous doses, respectively, may be excreted unchanged; the rest is excreted by the kidneys
as metabolites that appear to have no beta-blocking activity. The renal clearance of the stereoisomers does not exhibit stereo-selectivity in renal excretion.
Special populations
Geriatric Patients

The geriatric population may show slightly higher plasma concentrations of Metoprolol as a
combined result of a decreased metabolism of the drug in elderly population and a decreased
hepatic blood flow. However, this increase is not clinically significant or therapeutically relevant.
Renal Impairment
The systemic availability and half-life of Metoprolol in patients with renal failure do not differ to
a clinically significant degree from those in normal subjects.
Hepatic Impairment
Since the drug is primarily eliminated by hepatic metabolism, hepatic impairment may impact
the pharmacokinetics of Metoprolol. The elimination half-life of Metoprolol is considerably
prolonged, depending on severity (up to 7.2 h).
Clinical Studies
Hypertension
In controlled clinical studies, Metoprolol has been shown to be an effective antihypertensive
agent when used alone or as concomitant therapy with thiazide-type diuretics, at dosages of 100
to 450 mg daily. In controlled, comparative, clinical studies, Metoprolol has been shown to be as
effective an antihypertensive agent as propranolol, methyldopa, and thiazide-type diuretics, to be
equally effective in supine and standing positions.
Angina Pectoris
In controlled clinical trials, Metoprolol, administered two or four times daily, has been shown to
be an effective antianginal agent, reducing the number of angina attacks and increasing exercise
tolerance. The dosage used in these studies ranged from 100 to 400 mg daily. A controlled,
comparative, clinical trial showed that Metoprolol was indistinguishable from propranolol in the
treatment of angina pectoris.
Myocardial Infarction
In a large (1,395 patients randomized), double-blind, placebo-controlled clinical study,
Metoprolol was shown to reduce 3-month mortality by 36% in patients with suspected or definite
myocardial infarction.
Patients were randomized and treated as soon as possible after their arrival in the hospital, once

their clinical condition had stabilized and their hemodynamic status had been carefully
evaluated. Subjects were ineligible if they had hypotension, bradycardia, peripheral signs of
shock, and/or more than minimal basal rales as signs of congestive heart failure. Initial treatment
consisted of intravenous followed by oral administration of Metoprolol or placebo, given in a
coronary care or comparable unit. Oral maintenance therapy with Metoprolol or placebo was
then continued for 3 months. After this double-blind period, all patients were given Metoprolol
and followed up to 1 year.
The median delay from the onset of symptoms to the initiation of therapy was 8 hours in both the
Metoprolol- and placebo-treatment groups. Among patients treated with Metoprolol, there were
comparable reductions in 3-month mortality for those treated early (8 hours) and those in whom
treatment was started later. Significant reductions in the incidence of ventricular fibrillation and
in chest pain following initial intravenous therapy were also observed with Metoprolol and were
independent of the interval between onset of symptoms and initiation of therapy.
In this study, patients treated with Metoprolol received the drug both very early (intra-venously)
and during a subsequent 3-month period, while placebo patients received no beta-blocker
treatment for this period. The study thus was able to show a benefit from the overall Metoprolol
regimen but cannot separate the benefit of very early intravenous treatment from the benefit of
later beta-blocker therapy. Nonetheless, because the overall regimen showed a clear beneficial
effect on survival without evidence of an early adverse effect on survival, one acceptable dosage
regimen is the precise regimen used in the trial. Because the specific benefit of very early
treatment remains to be defined however, it is also reasonable to administer the drug orally to
patients at a later time as is recommended for certain other beta-blockers.

AMLOVAS M 5 MG/50 MG TABLET

Macleods Pharmaceuticals Pvt Ltd

MRP:Rs. 83.30 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Amlodipine(5 mg),Metoprolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.

How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Metoprolol(50 mg)
Uses
Metoprolol is a beta-blocker and used to treat high blood pressure, fast and irregular
heartbeat (cardiac arrhythmias especially supraventricular arrhythmia), chest pain
(angina pectoris), overactive thyroid gland (hyperthyroidism), heart failure, early
intervention in heart attack (myocardial infarction) and to prevent migraine attacks.
How it works
It works by relaxing blood vessels and slowing heart rate to improve blood flow and
decrease blood pressure.Early intervention and start of metoprolol in myocardial
infarction reduces infarct size and the incidence of ventricular fibrillation.
Common side effects

Gas or bloating, Depression or dizziness, Nausea, Tiredness, Constipation, Runny nose,

Lightheadedness, Cold hands and feet, A rash or itching on the skin, Vomiting, Rash or itching,
Stomach pain, Heartburn, Dry mouth
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.

It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

AMLOPIN M 5 MG/50 MG TABLET

USV Ltd
MRP:Rs. 81.50 for 1 strip(s) (10 tablet each)
Composition
Amlodipine(5 mg),Metoprolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Metoprolol(50 mg)

Uses
Metoprolol is a beta-blocker and used to treat high blood pressure, fast and irregular
heartbeat (cardiac arrhythmias especially supraventricular arrhythmia), chest pain
(angina pectoris), overactive thyroid gland (hyperthyroidism), heart failure, early
intervention in heart attack (myocardial infarction) and to prevent migraine attacks.
How it works
It works by relaxing blood vessels and slowing heart rate to improve blood flow and
decrease blood pressure.Early intervention and start of metoprolol in myocardial
infarction reduces infarct size and the incidence of ventricular fibrillation.
Common side effects

Gas or bloating, Depression or dizziness, Nausea, Tiredness, Constipation, Runny nose,

Lightheadedness, Cold hands and feet, A rash or itching on the skin, Vomiting, Rash or itching,
Stomach pain, Heartburn, Dry mouth
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.
It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

METOCARD AM TABLET 5 MG/50 MG

Torrent Pharmaceuticals Ltd

MRP:Rs. 82 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Amlodipine(5 mg),Metoprolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Metoprolol(50 mg)
Uses
Metoprolol is a beta-blocker and used to treat high blood pressure, fast and irregular
heartbeat (cardiac arrhythmias especially supraventricular arrhythmia), chest pain
(angina pectoris), overactive thyroid gland (hyperthyroidism), heart failure, early
intervention in heart attack (myocardial infarction) and to prevent migraine attacks.
How it works
It works by relaxing blood vessels and slowing heart rate to improve blood flow and
decrease blood pressure.Early intervention and start of metoprolol in myocardial
infarction reduces infarct size and the incidence of ventricular fibrillation.
Common side effects

Gas or bloating, Depression or dizziness, Nausea, Tiredness, Constipation, Runny nose,

Lightheadedness, Cold hands and feet, A rash or itching on the skin, Vomiting, Rash or itching,
Stomach pain, Heartburn, Dry mouth
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.
It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding

EVIMETO AM 5 MG/50 MG TABLET

Jubilant Life Sciences

MRP:Rs. 62 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Amlodipine(5 mg),Metoprolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.

How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Metoprolol(50 mg)
Uses
Metoprolol is a beta-blocker and used to treat high blood pressure, fast and irregular
heartbeat (cardiac arrhythmias especially supraventricular arrhythmia), chest pain
(angina pectoris), overactive thyroid gland (hyperthyroidism), heart failure, early
intervention in heart attack (myocardial infarction) and to prevent migraine attacks.
How it works
It works by relaxing blood vessels and slowing heart rate to improve blood flow and
decrease blood pressure.Early intervention and start of metoprolol in myocardial
infarction reduces infarct size and the incidence of ventricular fibrillation.
Common side effects

Gas or bloating, Depression or dizziness, Nausea, Tiredness, Constipation, Runny nose,

Lightheadedness, Cold hands and feet, A rash or itching on the skin, Vomiting, Rash or itching,
Stomach pain, Heartburn, Dry mouth
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.

It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

TELMA AM 40MG/5MG TABLET

Glenmark Pharmaceuticals Ltd
MRP:Rs. 150 for 1 strip(s) (15 tablet each)
Buy Now
Composition
Telmisartan(40 mg),Amlodipine(5 mg)
SALT INFORMATION
Telmisartan(40 mg)
Uses
Telmisartan belongs to a class of medicines known as angiotensin II receptor
blockers. It is used to treat high blood pressure, prevention and treatment of heart
attack (myocardial Infarction) and heart failure; when heart is unable to pump
sufficient blood. It is also used for kidney failure in patients with diabetes.
How it works
Telmisartan blocks the action of a substance (angiotensin II) responsible for
narrowing of the blood vessels. It relaxes the blood vessels; thereby lowering blood
pressure.
Common side effects

Low blood pressure, Rapid swelling of the facial skin, Itching, Cough, Vomiting, Bloating,
Hypersensitivity reactions, Muscle cramps and pain
Amlodipine(5 mg)
Uses

Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Expert advice

Get your blood pressure, potassium, and kidney function checked 1 week
after starting the medicine, then routinely after.

Consult your doctor about any dizziness or muscle weakness that doesn't go
away.

Get immediate medical help if you notice any swelling, especially around your
head and neck.

Do not start or continue telmisartan tablets and consult your doctor if you
are allergic (hypersensitive) to telmisartan or to any other ingredients of the
drug.

Pharmacokinetics of oral doses of telmisartan

This randomized, single-blind, parallel-group study was performed to assess
pharmacokinetic interactions potentially occurring during concomitant use of
telmisartan and nisoldipine. Patients with essential hypertension (n = 37) were
treated with once-daily doses of telmisartan, nisoldipine, or their combination for 6
weeks. The regimen was started at low dose with an increase of dosage after 3
weeks of treatment. AUC(ss) (132%; P < .01) of telmisartan applied in doses of 80
mg was significantly higher after concomitant application with nisoldipine (10 mg),
whereas CL/f(ss) (-54%; P < .05) and Vz/f(ss) (-72%; P < .05) were significantly
lower. Regarding pharmacokinetic parameters of nisoldipine, significant differences
between treatment groups were not detected. In conclusion, the results of this study
strongly suggest that concomitant treatment with nisoldipine enhances telmisartan
bioavailability in hypertensive individuals. Larger crossover trials will have to
establish these observations and investigate whether interaction of both drugs
affects telmisartan efficacy and tolerability in clinical use.

TELVAS AM 40MG TABLET

Aristo Pharmaceuticals Pvt Ltd

MRP:Rs. 58.50 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Telmisartan(40 mg),Amlodipine(5 mg)
SALT INFORMATION
Telmisartan(40 mg)
Uses
Telmisartan belongs to a class of medicines known as angiotensin II receptor
blockers. It is used to treat high blood pressure, prevention and treatment of heart
attack (myocardial Infarction) and heart failure; when heart is unable to pump
sufficient blood. It is also used for kidney failure in patients with diabetes.
How it works
Telmisartan blocks the action of a substance (angiotensin II) responsible for
narrowing of the blood vessels. It relaxes the blood vessels; thereby lowering blood
pressure.
Common side effects

Low blood pressure, Rapid swelling of the facial skin, Itching, Cough, Vomiting, Bloating,
Hypersensitivity reactions, Muscle cramps and pain
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Expert advice

Get your blood pressure, potassium, and kidney function checked 1 week
after starting the medicine, then routinely after.

Consult your doctor about any dizziness or muscle weakness that doesn't go
away.

Get immediate medical help if you notice any swelling, especially around your
head and neck.

Do not start or continue telmisartan tablets and consult your doctor if you
are allergic (hypersensitive) to telmisartan or to any other ingredients of the
drug.

TELSARTAN AM 40MG/5MG TABLET

Dr Reddy's Laboratories Ltd

MRP:Rs. 110 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Telmisartan(40 mg),Amlodipine(5 mg)
SALT INFORMATION
Telmisartan(40 mg)
Uses
Telmisartan belongs to a class of medicines known as angiotensin II receptor
blockers. It is used to treat high blood pressure, prevention and treatment of heart
attack (myocardial Infarction) and heart failure; when heart is unable to pump
sufficient blood. It is also used for kidney failure in patients with diabetes.
How it works
Telmisartan blocks the action of a substance (angiotensin II) responsible for
narrowing of the blood vessels. It relaxes the blood vessels; thereby lowering blood
pressure.

Common side effects

Low blood pressure, Rapid swelling of the facial skin, Itching, Cough, Vomiting, Bloating,
Hypersensitivity reactions, Muscle cramps and pain
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Expert advice

Get your blood pressure, potassium, and kidney function checked 1 week
after starting the medicine, then routinely after.

Consult your doctor about any dizziness or muscle weakness that doesn't go
away.

Get immediate medical help if you notice any swelling, especially around your
head and neck.

Do not start or continue telmisartan tablets and consult your doctor if you
are allergic (hypersensitive) to telmisartan or to any other ingredients of the
drug.

TELISTA AM 40MG/5MG TABLET

Lupin Ltd

MRP:Rs. 99.50 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Telmisartan(40 mg),Amlodipine(5 mg)
SALT INFORMATION
Telmisartan(40 mg)
Uses
Telmisartan belongs to a class of medicines known as angiotensin II receptor
blockers. It is used to treat high blood pressure, prevention and treatment of heart
attack (myocardial Infarction) and heart failure; when heart is unable to pump
sufficient blood. It is also used for kidney failure in patients with diabetes.
How it works

Telmisartan blocks the action of a substance (angiotensin II) responsible for

narrowing of the blood vessels. It relaxes the blood vessels; thereby lowering blood
pressure.
Common side effects

Low blood pressure, Rapid swelling of the facial skin, Itching, Cough, Vomiting, Bloating,
Hypersensitivity reactions, Muscle cramps and pain
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Expert advice

Get your blood pressure, potassium, and kidney function checked 1 week
after starting the medicine, then routinely after.

Consult your doctor about any dizziness or muscle weakness that doesn't go
away.

Get immediate medical help if you notice any swelling, especially around your
head and neck.

Do not start or continue telmisartan tablets and consult your doctor if you
are allergic (hypersensitive) to telmisartan or to any other ingredients of the
drug.

TELLZY AM 40MG/5MG TABLET

Alembic Pharmaceuticals Ltd

MRP:Rs. 149.91 for 1 strip(s) (15 tablet each)

Buy Now
Composition
Telmisartan(40 mg),Amlodipine(5 mg)
SALT INFORMATION
Telmisartan(40 mg)
Uses
Telmisartan belongs to a class of medicines known as angiotensin II receptor
blockers. It is used to treat high blood pressure, prevention and treatment of heart
attack (myocardial Infarction) and heart failure; when heart is unable to pump
sufficient blood. It is also used for kidney failure in patients with diabetes.

How it works
Telmisartan blocks the action of a substance (angiotensin II) responsible for
narrowing of the blood vessels. It relaxes the blood vessels; thereby lowering blood
pressure.
Common side effects

Low blood pressure, Rapid swelling of the facial skin, Itching, Cough, Vomiting, Bloating,
Hypersensitivity reactions, Muscle cramps and pain
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.
How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Expert advice

Get your blood pressure, potassium, and kidney function checked 1 week
after starting the medicine, then routinely after.

Consult your doctor about any dizziness or muscle weakness that doesn't go
away.

Get immediate medical help if you notice any swelling, especially around your
head and neck.

Do not start or continue telmisartan tablets and consult your doctor if you
are allergic (hypersensitive) to telmisartan or to any other ingredients of the
drug.

AMLOKIND-AT 5 MG/50 MG TABLET

Mankind Pharma Ltd

MRP:Rs. 17.49 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Amlodipine(5 mg),Atenolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.

How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Atenolol(50 mg)
Uses
Atenolol is used to control high blood pressure (hypertension), prevent chest pain
(angina), treat uneven heart beats (arrhythmias) and in the early treatment
following a heart attack (myocardial infarction).
How it works
Atenolol belongs to class of medications called beta blockers. It acts by blocking
receptors (beta-1 adrenergic receptor) in the heart and peripheral blood vessels
resulting in slowing of heart rate and relaxing of blood vessels thereby lowering
blood pressure. Atenolol reduces oxygen requirement at any level of activity making
it useful for long-term management of heart attacks caused by restricted blood flow
to the heart.
Common side effects

Rapid weight gain, Diarrhea and nausea, Excessive tiredness, Dizziness or lightheadedness,
Drowsiness, Cough or shortness of breath, Swelling of hands and feet, Cns depression, Fainting
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.

It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

Clinical pharmacokinetics of atenolol

Atenolol is a hydrophilic betareceptor blocking drug, which is predominantly
eliminated via the kidneys, only about 5% of the atenolol is metabolised by the liver.
After oral administration atenolol is incompletely absorbed from the intestine, so
about 50% of the beta blocker are finally biovailable. In plasma only 3% of atenolol
are protein-bound. There exists a linear relationship between the atenolol plasma
levels and the degree of beta blocking effect measured by inhibition of the exerciseinduced tachycardia. No correlation was found between plasma levels of atenolol
and blood pressure lowering activity of the drug. After oral administration
elimination half life of atenolol is calculated from 6 to 9 h by different authors. In
patients with impaired renal function elimination half life of atenolol gradually
increases to values of 36 h in uraemic patients (glomerular filtration rate (GFR) less
than 10 ml/min). Between GFR and atenolol plasma clearance as well as renal
clearance a close significant correlation is described. Prolongation of elimination half
life requires a dosage adjustment of atenolol in patients with renal failure. A marked
interaction of atenolol is found when calcium or aluminium hydroxide are
concurrently administered with the beta blocker whereas cimetidine does not
influence atenolol kinetics.

AMLONG A 5 MG/50 MG TABLET

Micro Labs Ltd

MRP:Rs. 87.90 for 1 strip(s) (15 tablet each)

Buy Now
Composition
Amlodipine(5 mg),Atenolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.

How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Atenolol(50 mg)
Uses
Atenolol is used to control high blood pressure (hypertension), prevent chest pain
(angina), treat uneven heart beats (arrhythmias) and in the early treatment
following a heart attack (myocardial infarction).
How it works
Atenolol belongs to class of medications called beta blockers. It acts by blocking
receptors (beta-1 adrenergic receptor) in the heart and peripheral blood vessels
resulting in slowing of heart rate and relaxing of blood vessels thereby lowering
blood pressure. Atenolol reduces oxygen requirement at any level of activity making
it useful for long-term management of heart attacks caused by restricted blood flow
to the heart.
Common side effects

Rapid weight gain, Diarrhea and nausea, Excessive tiredness, Dizziness or lightheadedness,
Drowsiness, Cough or shortness of breath, Swelling of hands and feet, Cns depression, Fainting
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.

It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

AMLOVAS-AT 5 MG/50 MG TABLET

Macleods Pharmaceuticals Pvt Ltd

MRP:Rs. 61.50 for 1 strip(s) (15 tablet each)

Buy Now
Composition
Amlodipine(5 mg),Atenolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.

How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Atenolol(50 mg)
Uses
Atenolol is used to control high blood pressure (hypertension), prevent chest pain
(angina), treat uneven heart beats (arrhythmias) and in the early treatment
following a heart attack (myocardial infarction).
How it works
Atenolol belongs to class of medications called beta blockers. It acts by blocking
receptors (beta-1 adrenergic receptor) in the heart and peripheral blood vessels
resulting in slowing of heart rate and relaxing of blood vessels thereby lowering
blood pressure. Atenolol reduces oxygen requirement at any level of activity making
it useful for long-term management of heart attacks caused by restricted blood flow
to the heart.
Common side effects

Rapid weight gain, Diarrhea and nausea, Excessive tiredness, Dizziness or lightheadedness,
Drowsiness, Cough or shortness of breath, Swelling of hands and feet, Cns depression, Fainting
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.

It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

AMLOPRES AT 5 MG/50 MG TABLET

Cipla Ltd

MRP:Rs. 84.50 for 1 strip(s) (15 tablet each)

Buy Now
Composition
Amlodipine(5 mg),Atenolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.

How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Atenolol(50 mg)
Uses
Atenolol is used to control high blood pressure (hypertension), prevent chest pain
(angina), treat uneven heart beats (arrhythmias) and in the early treatment
following a heart attack (myocardial infarction).
How it works
Atenolol belongs to class of medications called beta blockers. It acts by blocking
receptors (beta-1 adrenergic receptor) in the heart and peripheral blood vessels
resulting in slowing of heart rate and relaxing of blood vessels thereby lowering
blood pressure. Atenolol reduces oxygen requirement at any level of activity making
it useful for long-term management of heart attacks caused by restricted blood flow
to the heart.
Common side effects

Rapid weight gain, Diarrhea and nausea, Excessive tiredness, Dizziness or lightheadedness,
Drowsiness, Cough or shortness of breath, Swelling of hands and feet, Cns depression, Fainting
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.

It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

AMCARD AT 5 MG/50 MG TABLET

Systopic Laboratories Pvt Ltd

MRP:Rs. 28.50 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Amlodipine(5 mg),Atenolol(50 mg)
SALT INFORMATION
Amlodipine(5 mg)
Uses
Amlodipine is used to treat high blood pressure (hypertension) and severe pain in
chest.

How it works
Amlodipine belongs to a class of drugs called calcium channel blocker. It reduces
the amount of calcium that enters the smooth muscles of the blood vessels and
heart. As muscle cells require calcium to contract, reducing the flow of calcium
causes the muscle cells to relax and blood vessels to dilate, reducing blood
pressure, force and rate of the heartbeat. It improves blood and oxygen supply to
the heart muscles.
Common side effects

Andheadache, Facial flushing, Lightheadedness, Swelling of hands and feet, Drowsiness, Upset
stomach, Chest pain, Abdominal or stomach pain, Fainting, Dizziness, Pounding heartbeat,
Extreme tiredness
Atenolol(50 mg)
Uses
Atenolol is used to control high blood pressure (hypertension), prevent chest pain
(angina), treat uneven heart beats (arrhythmias) and in the early treatment
following a heart attack (myocardial infarction).
How it works
Atenolol belongs to class of medications called beta blockers. It acts by blocking
receptors (beta-1 adrenergic receptor) in the heart and peripheral blood vessels
resulting in slowing of heart rate and relaxing of blood vessels thereby lowering
blood pressure. Atenolol reduces oxygen requirement at any level of activity making
it useful for long-term management of heart attacks caused by restricted blood flow
to the heart.
Common side effects

Rapid weight gain, Diarrhea and nausea, Excessive tiredness, Dizziness or lightheadedness,
Drowsiness, Cough or shortness of breath, Swelling of hands and feet, Cns depression, Fainting
Expert advice
Take the appropriate dose of amlodipine with any liquid, with or without food at any
fixed time each day.
Do not drive if you experience side effects like dizziness, sleepiness or blurred vision
on taking amlodipine.
Check your blood pressure one week after starting this drug and conuslt your doctor
if it has not improved.

It can cause ankle or foot swelling. Consult your doctor if it it doesn't improve over
time.
Do not start or continue amlodipine tablets and consult your doctor:

If you are allergic (hypersensitive) to amlodipine or any of its other

ingredients.

If you are pregnant or planning to become pregnant or breast feeding.

LOSAR 50MG TABLET

Unichem Laboratories Ltd

MRP:Rs. 74.65 for 1 strip(s) (15 tablet each)

Buy Now
Composition
Losartan(50 mg)
SALT INFORMATION
Losartan(50 mg)
Uses
Losartan is used in the treatment of high blood pressure (essential hypertension),
kidney disease in adult patients with high blood pressure and type 2 diabetes

mellitus, treatment of chronic heart failure, and prevention of stroke in adult

patients high blood pressure and heart disorder (left ventricular hypertrophy).
How it works
Losartan belongs to a class of medications called angiotensin II receptor
antagonists. It works by blocking the action of certain natural substances that
tighten the blood vessels and also by inhibiting the aldosterone secreting effect of
angiotensin II, allowing the blood to flow more smoothly and the heart to pump
more efficiently.
Common side effects

Decreased sensitivity to touch, Heartburn, Hoarseness, Leg pain, Swelling of face and lips, Bone/
joint pain, Throat, Back pain, Difficulty in swallowing, Muscle cramp, Chest pain
Expert advice

The drug can make you dizzy for first few days. Be careful while driving and
while operating heavy machinery.

Consult your doctor if you get dizziness, fatigue, cough, or throat irritation
that doesn't go away.

Do not take this drug if you are pregnant or breast feeding.

Check your blood pressure 1 week after starting the drug and consult your
doctor if it does not improve.

Consult your doctor immediately if you have unexplained muscle pain,

tenderness, or weakness especially if you also have fever, unusual tiredness,
and dark colored urine

Clinical pharmacokinetics of losartan.

Losartan is the first orally available angiotensin-receptor antagonist without agonist
properties. Following oral administration, losartan is rapidly absorbed, reaching
maximum concentrations 1-2 hours post-administration. After oral administration
approximately 14% of a losartan dose is converted to the pharmacologically active
E 3174 metabolite. E 3174 is 10- to 40-fold more potent than its parent compound
and its estimated terminal half-life ranges from 6 to 9 hours. The pharmacokinetics
of losartan and E 3174 are linear, dose-proportional and do not substantially change
with repetitive administration. The recommended dosage of losartan 50 mg/day can
be administered without regard to food. There are no clinically significant effects of
age, sex or race on the pharmacokinetics of losartan, and no dosage adjustment is
necessary in patients with mild hepatic impairment or various degrees of renal

insufficiency. Losartan, or its E 3174 metabolite, is not removed during

haemodialysis. The major metabolic pathway for losartan is by the cytochrome P450
(CYP) 3A4, 2C9 and 2C10 isoenzymes. Overall, losartan has a favorable drug-drug
interaction profile, as evidenced by the lack of clinically relevant interactions
between this drug and a range of inhibitors and stimulators of the CYP450 system.
Losartan does not have a drug-drug interaction with hydrochlorothiazide, warfarin or
digoxin. Losartan should be avoided in pregnancy, as is the case with all other
angiotensin-receptor antagonists. When given in the second and third trimester of
pregnancy, losartan is often associated with serious fetal toxicity. Losartan is a
competitive antagonist that causes a parallel rightward shift of the concentrationcontractile response curve to angiotensin-II, while E 3174 is a noncompetitive
"insurmountable" antagonist of angiotensin-II. The maximum recommended daily
dose of losartan is 100mg, which can be given as a once-daily dose or by splitting
the same total daily dose into two doses. Losartan reduces blood pressure
comparably to other angiotensin-receptor antagonists. Losartan has been
extensively studied relative to end-organ protection, with studies having been
conducted in diabetic nephropathy, heart failure, post-myocardial infarction and
hypertensive patients with left ventricular hypertrophy. The results of these studies
have been sufficiently positive to support a more widespread use of angiotensinreceptor antagonists in the setting of various end-organ diseases. Losartan, like
other angiotensin-receptor antagonists, is devoid of significant adverse effects.

LOSACAR-50 TABLET
ZYDUS CADILA

MRP:Rs. 49.81 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Losartan(50 mg)

SALT INFORMATION
Losartan(50 mg)
Uses
Losartan is used in the treatment of high blood pressure (essential hypertension),
kidney disease in adult patients with high blood pressure and type 2 diabetes
mellitus, treatment of chronic heart failure, and prevention of stroke in adult
patients high blood pressure and heart disorder (left ventricular hypertrophy).
How it works
Losartan belongs to a class of medications called angiotensin II receptor
antagonists. It works by blocking the action of certain natural substances that
tighten the blood vessels and also by inhibiting the aldosterone secreting effect of
angiotensin II, allowing the blood to flow more smoothly and the heart to pump
more efficiently.
Common side effects

Decreased sensitivity to touch, Heartburn, Hoarseness, Leg pain, Swelling of face and lips, Bone/
joint pain, Throat, Back pain, Difficulty in swallowing, Muscle cramp, Chest pain
Expert advice

The drug can make you dizzy for first few days. Be careful while driving and
while operating heavy machinery.

Consult your doctor if you get dizziness, fatigue, cough, or throat irritation
that doesn't go away.

Do not take this drug if you are pregnant or breast feeding.

Check your blood pressure 1 week after starting the drug and consult your
doctor if it does not improve.

Consult your doctor immediately if you have unexplained muscle pain,

tenderness, or weakness especially if you also have fever, unusual tiredness,
and dark colored urine.

ZAART 50MG TABLET

Cipla Ltd

MRP:Rs. 49.75 for 1 strip(s) (10 tablet each)

Buy Now
Composition
Losartan(50 mg)
SALT INFORMATION

Losartan(50 mg)
Uses
Losartan is used in the treatment of high blood pressure (essential hypertension),
kidney disease in adult patients with high blood pressure and type 2 diabetes
mellitus, treatment of chronic heart failure, and prevention of stroke in adult
patients high blood pressure and heart disorder (left ventricular hypertrophy).
How it works
Losartan belongs to a class of medications called angiotensin II receptor
antagonists. It works by blocking the action of certain natural substances that
tighten the blood vessels and also by inhibiting the aldosterone secreting effect of
angiotensin II, allowing the blood to flow more smoothly and the heart to pump
more efficiently.
Common side effects

Decreased sensitivity to touch, Heartburn, Hoarseness, Leg pain, Swelling of face and lips, Bone/
joint pain, Throat, Back pain, Difficulty in swallowing, Muscle cramp, Chest pain
Expert advice

The drug can make you dizzy for first few days. Be careful while driving and
while operating heavy machinery.

Consult your doctor if you get dizziness, fatigue, cough, or throat irritation
that doesn't go away.

Do not take this drug if you are pregnant or breast feeding.

Check your blood pressure 1 week after starting the drug and consult your
doctor if it does not improve.

Consult your doctor immediately if you have unexplained muscle pain,

tenderness, or weakness especially if you also have fever, unusual tiredness,
and dark colored urine.

LOSARTAN 50MG TABLET

Jan Aushadhi

MRP:Rs. 9.02 for 1 strip(s) (10 tablet each)

Buy Now
Composition

Losartan(50 mg)
SALT INFORMATION
Losartan(50 mg)
Uses
Losartan is used in the treatment of high blood pressure (essential hypertension),
kidney disease in adult patients with high blood pressure and type 2 diabetes
mellitus, treatment of chronic heart failure, and prevention of stroke in adult
patients high blood pressure and heart disorder (left ventricular hypertrophy).
How it works
Losartan belongs to a class of medications called angiotensin II receptor
antagonists. It works by blocking the action of certain natural substances that
tighten the blood vessels and also by inhibiting the aldosterone secreting effect of
angiotensin II, allowing the blood to flow more smoothly and the heart to pump
more efficiently.
Common side effects

Decreased sensitivity to touch, Heartburn, Hoarseness, Leg pain, Swelling of face and lips, Bone/
joint pain, Throat, Back pain, Difficulty in swallowing, Muscle cramp, Chest pain
Expert advice

The drug can make you dizzy for first few days. Be careful while driving and
while operating heavy machinery.

Consult your doctor if you get dizziness, fatigue, cough, or throat irritation
that doesn't go away.

Do not take this drug if you are pregnant or breast feeding.

Check your blood pressure 1 week after starting the drug and consult your
doctor if it does not improve.

Consult your doctor immediately if you have unexplained muscle pain,

tenderness, or weakness especially if you also have fever, unusual tiredness,
and dark colored urine.