ABSTRACT

OVERVIEW OF DEMOGRAPHIC AND CLINICAL CHARACTERISTICS OF PATIENT

WITH FEBRILE NEUTROPENIA AFTER CHEMOTHERAPY IN DR. SARDJITO
HOSPITAL 2014-2015
Iswandi Darwis1, Mardiah Suci Hardianti2
Resident in Department of Internal Medicine
2
Hematology-Oncology Divisions, Department of Internal Medicine Faculty of Medicine
Universitas Gadjah Mada Dr. Sardjito Hospital
1

Background. Febrile neutropenia is a frequent complication in patients with cancer who are
undergoing chemotherapy and can lead to death if untreated. Dr. Sardjito hospital does
chemotherapy in patients, but does not have data on the demographic and clinical picture of
febrile neutropenic patients after chemotherapy. The purpose of this study is to describe the
demographic and clinical patient with febrile neutropenia after chemotherapy in Dr. Sardjito
Hospital in 2014-2015.
Methods. This study is a retrospective study, data is extracted from medical records of patients
who experience febrile neutropenia receiving chemotherapy from the year 2014 to 2015. The
population in this study were all patients aged over 18 years who are undergoing chemotherapy
and has a febrile neutropenia treated in Dr. Sardjito Hospital in 2014-2015.
result. Obtained 23 patients febrile neutropenia after chemotherapy with a high risk of 69.57%.
The mean age is 55 years old male patient (52.17%) and 56.52% high school background.
Mortality for patients as much as 43.48% with the cause of death was septic shock (55.56%).
Length of stay of patients an average of 8 days. Most types of cancer are given chemotherapy is
the NHL and also many causes febrile neutropenia is RCHOP 34.78%. On examination of blood
cultures in patients on admission, obtained growth of germs as much as 13,04%, include
Streptococcus viridans 66.67% that still sensitive to cephalosporins 3rd generation.
Conclusions. 23 cases of febrile neutropenia were found with a mortality rate of 43.48% with the
cause of death was septic shock.
Keywords. Fever, mortality, neutropenia