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613 Vowwme 11+ Issue 5 'a8 09 DERMATOLC Improved Texture and Appearance of Human Facial Skin After Daily Topical Application of Barley Produced, Synthetic, Human-like Epidermal Growth Factor (EGF) Serum Jonathan M. Schouest BS, Teresa K. Luu MD, and Ronald L. Moy MD, Moy-Fincher-Chipps Facial Phases and Dermatology, Beverly Hills, CA A three month, open-label, single center study was conducted to determine whether a uniquely darived serum containing barey bio- engineered, humanike epidermal growth factor protein could improve visible signs af photadamage and aging in facial skin. Twenty: rine females, aged 39 to 75 years, with mid to severe, fine and course chytids, photodamage, and pigmentation were enrolled, Subjects then applied the treatment serum par the prescribed protocol twice-daily for 3 months, in addition to the use of a basic sunscraen and facial cleanser. In-person clinical evaluations and subject self-assessment questionnaires were administered at each follow up visit. In addition, clinical photography was completed at baseline, and each subsequent visit. Clinical evaluations showed Statistically significant improvement in the appearance of fine lines and rhytids, skin texture, pore size, and various dyschromatic conditions apparent within the first month of use, and continuing improvement trends for the duration of the study. The treatment serum was well tolerated with minimal treatment-related complications reported throughout. E! icacy of this novel serum and treat- ment protocol resulted in meaningful improvements in photodamage and visible signs of aging, Jor Dermatol. 2012;1 1(5)613-620. reat in aw vty fms and is elena Perens eS ono so 9 rosie nee recaps fem: perl grow tr caves primary rogue and mebiting copay onto ‘Siecyn foots nd arch muscle eal. These fi Ihr" Aa hana nawaly age, EOF rere ECFR) on Fatrspons opens decose "hain oduenud

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