American Society for Clinical Pathology

2004 Resident In-Service Examination

Item Descriptors
Anatomical Pathology
Cytopathology
1.
Desmoid-type fibromatosis; no metastatic potential
2.
Hodgkin's disease; fine-needle aspirate neck
3.
Mesothelial cell; staining pattern
4.
Papillary carcinoma; aspirate thyroid nodule
5.
Chromagranin; fine-needle aspiration liver
6.
Mesothelial cells; effusions
7.
Fine-needle aspiration biopsy; nodular fasciitis
8.
Carcinoma of breast; intracytoplasmic lumens
9.
Radiation effect; Pap smear
10.
Cervical smears; tissue sections
11.
High grade squamous intraepithelial lesion; Pap smear
12.
Atypical squamous cells of undetermined significance; reporting definition
13.
Carcinoma; fine-needle aspiration of breast mass
14.
Subareolar abscess of the breast; ruptured epidermal inclusion cyst
15.
Meningioma; fine-needle aspiration of a scalp lesion
16.
Adenocarcinoma in situ; Pap smear
17.
Colloid carcinoma; fine-needle aspirate breast
18.
Bilateral mass; fine-needle aspirate breast
19.
Reserve cells; small cell undifferentiated carcinoma
20.
Bronchioalveolar carcinoma; fine-needle aspiration lung
21.
Follicle center lymphoma; fine-needle aspiration lymph nodes
22.
Aspirate of solitary thyroid nodule; lesion excised
23.
Busulfan; mimic cancer
24.
Course of acyclovir; Pap smear
25.
Cryptococcus neoformans; fluid aspirated thigh abscess
26.
Warthin's tumor; bilateral parotid tumor
27.
Gleason pattern3+4; prostatic adenocarcinoma
28.
Contamination; urine cytology specimen
29.
Sarcomatoid renal carcinoma; any histologic type
30.
Chromophobe renal carcinoma; outcome
31.
Renal carcinoma; t(X;1) (p11.2;q21) chromosome translocation
32.
Endometrial cells; Bethesda
33.
Intractable gastric ulcers duodenal wall mass; peripancreatic lymph node
34.
Benign mixed tumor; fine-needle aspiration jaw
35.
Warthin tumor; fine-needle aspiration parotid
36.
Small cell carcinoma; sputum
Forensic Pathology
37.
Hypothermia; Anatomic findings
38.
Stomach contents; cocaine toxicity
39.
Incised wound; laceration
40.
Designer drugs; modifying the structure
41.
Gunshot wound; exit
42.
Postmortem change; lesions
43.
Atlantooccipital dislocation; vehicle accident death
44.
Vitreous fluid; hyperglycemia
45.
Drowning; other causes of death
46.
Ateriosclerotic heart disease; sudden and unexpected death
47.
Postmortem interval; > 16 hours
48.
Temporal and frontal lobe contusions; fall on the back of the head
49.
Gunshot wound; high velocity military rifle
50.
Injury on the arm; bite mark impression
51.
Sudden infant death syndrome; heart
52.
Man without a spleen; Gram stain of meninges
53.
Manual strangulation; fracture of the hyoid bone
54.
Homicide; manner of death
55.
Mechanism of death; septicemia

Surgical Pathology
56.
Pagets disease; regional carcinoma
57.
Thyroid cancer; age
58.
Breast neoplasms; worst prognosis
59.
Intramuscular myxoma; gelatinous tumor of the thigh
60.
Gynecomastia; Ultrastructural features
61.
Intratubular germ cell neoplasia; placental alkaline phosphatase
62.
Anogenital verrucous carcinoma; description
63.
Renomedullary interstitial cell tumor
64.
Renal artery; Fibromuscular dysplasia
65.
Adenocarcinoma of the urinary bladder; enteric carcinomas
66.
Erythema nodosum; characterization
67.
Contact allergy; Lichenoid interface dermatitis
68.
Progressive multifocal leukoencephalopathy; characteristics
69.
Fibroadenoma of the breast; greatest incidence
70.
Mulitcystic renal dysplasia; renal mass, primitive ducts
71.
Dermatofibrosarcoma protuberans; CD34 positive
72.
Subacute sclerosing panencephalitis; slowly progressive neurodegenerative disease
73.
Osteoblastoma; flat bones
74.
Dermatitis herpetiformis; gluten-sensitive enteropathy
75.
Colon biopsy; labeling of collagen
76.
Pulmonary lesion; lumen of a large airway
77.
Seminoma
78.
Cervical tunnel clusters; dilated endocervical glands
79.
Testicular tumor; 1-year-old
80.
Solitary fibrous tumor of pleura; increased recurrence
81.
Familial adenomatous polyposis syndrome; genetic abnormality
82.
Ground glass hepatocytes; Hepatitis B
83.
Malakoplakia; Escherichia coli
84.
Primary sclerosing cholangitis; primary biliary cirrhosis
85.
Metastatic papillary cancer; good prognosis
86.
Hashimoto's thyroiditis; thyromegaly
87.
Giant cell (temporal) arthritis; Associated findings
88.
Pure hepatic canalicular cholestasis; sepsis
89.
Adenomatoid tumor
90.
Cerebral hematoma metastatic tumor; beta HCG
91.
Kaposi's sarcoma; multiple organs
92.
Biopsy from the great toe; polarized light
93.
Cervical lymph node biopsy; Epstein Barr-virus testing
94.
Enchondroma; low grade central chondrosarcoma
95.
Gastrectomy specimen; ascites and bilateral ovarian masses
96.
Osteoarthritis; femoral head
97.
Yelloe fever; necrosis
98.
Small intestinal tumor; interstitial cells of Cajal
99.
Low grade sil; eventual regression
100.
Gastrointestinal tract dysplasia; unequivocally neoplastic epithelium
101.
Gallbladder; stones
102.
Adenocarcinoma of the lung; predictor of survival
103.
Invasive mammary carcinoma; appearance
104.
Liposarcomas; prognostic indicator
105.
Thymoma; myasthenia gravis
106.
Polymorphous low-grade adenocarcinoma of minor salivary gland; oral cavity
107.
Lobular carcinoma of the breast; Classic-type invasive
108.
Pseudoangiomatous change; breast
109.
Inflammatory breast cancer; dermal lymphatic invasion
110.
Osteoid osteoma; osteoblastoma
111.
Common primary malignant neoplasm; malignant fibrous histiocytoma
112.
Nodular fasciitis; characteristics
113.
Epithelioid sarcoma; positive for cytokeratins
114.
Esophagitis; mid-esophagus biopsy
115.
Crohn's disease; a gastric biopsy
116.
Anti-gliadin antibodies; lymphocytic colitis

117.
118.
119.
120.
121.
122.
123.
124.
125.
126.
127.

Peutz-Jehger's polyposis; small bowel

Jejuno-ileal carcinoid tumors; fibroblastic reaction
Ulcerative colitis; biopsies
Colon biopsies; H&E and trichrome-stained
Focal nodular hyperplasia; young women
Genetic hemochromatosis; stainable iron
Primary sclerosing cholangitis; cholangiocarcinoma
Esophageal adenocarcinoma; gastroesophageal reflux
Helicobacter pylori gastritis; atrophic gastritis
Gastric adenocarcinoma; atrophic gastritis
Gastric stromal tumors; c-kit gene

Clinical Pathology
Clinical Chemistry
128
Major intracellular cation; K+
129.
Prostate specific antigen; monitoring
130.
Serum osmolality; calculation
131.
Transthyretin; nutritional status
132.
Distal renal tubular acidosis; normal anion gap
133.
Loop diuretics; mechanism
134.
Methanol ingestion; serum osmole gap
135.
LDL cholesterol levels; 160 mg/dL
136.
LDL subclasses; Higher risk
137.
PKU; screening tests
138.
Pituitary gland; prolactin secreting tumor
139.
Method comparison; precision
140.
Fetal fibronectin; negative
141.
Diabetes Mellitus; Fructosamine
142.
Acute leukemia; elevated potassium
143.
Sensitivity of MCV; screen iron deficiency
144.
Distribution of the values: 25th percentile
145.
NT-proBNP: description
146.
Linearity; regression
147.
Cholesterol; maximum bias
148.
CML in blast crisis; glucose
149.
Fasting hypoglycemia; C-peptide
150.
Blunt head trauma; distinguishing fluids
151.
Canavan disease; mutation in aspartoacylase
152.
Fetal fibronectin; preterm labor
153.
Nitric oxide; peroxynitric acid
154.
BNP; congestive heart failure
155.
Drugs of abuse; metabolite of crack cocaine
156.
High-sensitivity C-reactive protein; levels of >15 mg/L indicate active inflammation
157.
Circulating alkaline phosphatase; condition

Hematopathology
159.
Hodgkins disease; lymph node excision
160.
Plasma cell leukemia; peripheral blood smear
161.
Sickle cell disease; hemoglobin electrophoresis patterns
162.
Small megakaryocytes; chronic myelogenous leukemia
163.
Abetalipoproteinemia; peripheral blood smear
164.
Chronic myelomonocytic leukemia; peripheral blood smear
165.
Anemia of chronic disease; lymphadenopathy
166.
Plasma cell myeloma; WHO
167.
Severe neutropenia in the neonatal age; bacterial sepsis
168.
chronic myelogenous leukemia; absolute basophilia
169.
Chloroacetate esterase; myeloid sarcoma
170.
Beta-thalassemia trait; hemoglobin A2
171.
Hyperdiploid karyotype; peripheral blood slide
172.
Toxoplasmosis; lymph node

173.
174.
175.
176.
177.
178.
179.
180.
181.
182.
183.
184.
185.
186.
187.
188.
189.
190.
191.
192.
193.
194.
195.
196.
197.
198.
199.
200.
201.
202.
203.

Mantle cell lymphoma; CD5-expression

CD15 positive neoplastic cells; slide
Monoclonal chronic large granular lymphocyte proliferations; neutropenia
Acute lymphoytic leukemia; cytochemical reactions
Hairy cell leukemia; tartrate-resistant acid phosphatase
Thrombotic thrombocytopenic purpura; platelet count
Refractory anemia; peripheral blood smear and laboratory studies
S-beta thalassemia; hemoglobin electrophoresis
Platelet function; inhibition
Bernard-Soulier disease; platelet aggregation study
Essential thrombocythemia; platelet count
B-cell lymphoma; immunoglobulin
Post-transfusion purpura; P1A1 antigen
B-cells; Hairy cell leukemia
Cold agglutinin disease; red cell finding
Alder-Reilly anomaly; mucopolysaccharidoses
Thrombotic thrombocytopenic purpura; pathogenesis
Factor XII deficiency; bleeding risk
Liver disease; coagulation results
Viral infection; blood smear shown
Osteoblasts; bone marrow smear
Chediak-Higashi syndrome; peripheral blood smear
Thrombotic thrombocytopenic purpura; blood smear
Specimen requirement for CBC; Quality Control
Spleen; PAS/diastase stains
Mean cell volume (MCV); hyperglycemia
nemias Hemolytic
Megaloblastic anemia; bone marrow aspirate smear
Prothrombin G20210A mutation; predispositions
Hereditary bleeding disorder; von Willebrand disease
Platelet glycoprotein Ib; von Willebrand factor

Microbiology
204.
Coxsackieviruses; persistent viral infection
205.
Susceptibility testing; disk selection
206.
Listeria; gram positive bacillus
207.
Staphylococcus aureus; coagulase test
208.
Staphylococcus aureus; colony characterizations
209.
Prevotella intermedi; pleural fluid
210.
Granulomatous dermatitis; microscopic appearance
211.
Anaplasma phagocytophilia; human granulocytic ehrilichiosis (HE)
212.
Rickettsia rickettssii; camping trip
213.
Staphylococcus aureus; mec A gene
214.
FTA-ABS test; Treponema pallidum
215.
Streptococcus pyogenes; blood culture slide
216.
Enterococcus faecalis; blood culture slide
217.
Stool assay; post-antibiotic diarrhea
218.
Ascaris lumbricoides; cysticercosis
219.
Highly pathogenic; non immunocompromised human hosts
220.
Bartonella henselae; cat scratch disease
221.
Pneumocococus; erythromycin resistance
222.
Mycobacterium tuberculosis; nitrate positive
223.
Trichophyton species; infections of hair follicles
224.
Penicillin resistant S. pneumoniae; oxacillin disk
225.
Parvovirus B19; "fifth's" disease
226.
Clostridium difficile toxin assays; hospitalized adult patient
227.
Neonate sepsis; blood culture
228.
Bovine spongioform encephalopathy; Creutzfeldt-Jacob disease
229.
Epstein-Barr virus infection; post-transplant lymphoproliferative disorders
230.
Malarial infection; red blood cell morphologic alterations
231.
Colonic spirochetosis; identified histologically
232.
Toxoplasma encephalitis; multifocal necrotizing lesions

233.
234.
235.
236.
237.
238.
239.
240.

Cryptococcal meningitis; CSF titers of cryptococcal antigen

Cytomegalovirus; Latent infection
SARS; Coronavirus
West Nile Virus; meningoencephalitis
Food-borne infections; screening
Anaerobe specimens; synovial fluid
Enterobius vermicularis; Cellulose tape preparations
Actinomyces israelii; oral surgery

Transfusion Medicine
241.
Irradiation of Blood; CMV
242.
Red blood cell preservative or; approved shelf life
243.
Plasmapheresis for TTP; replacement solution
244.
Cord red blood cells; Lea
245.
Transfusion records; FDA
246.
Dosage; Kidd
247.
Gamma irradiation; GVHD
248.
Cold-reactive agglutinin; anti-I
249.
TRALI; pulmonary edema
250.
Autologous donor; Requirements
251.
Plasmodium vivax; Fy(a-b-)
252.
Transfusion reaction; additional transfusions
253.
Platelet pheresis donors; Requirement
254.
HLA-identical match; siblings
255.
Enzyme treatment; S antigen
256.
Donor reaction; treatment is
257.
Blood preservation; pH
258.
Massively transfused patient; bleeding
259.
HIV infections; EIA-detectable antibodies
260.
Critical titer of anti-D; amniocentesis
261.
TRALI; anti-leukocyte antibodies
262.
Leukocyte-reduced Red Blood Cells; cytomegalovirus
263.
Infectious mononucleosis; anti-I
264.
Massive transfusion; platelet transfusion
265.
Donor Collection; additional blood
266.
Chronic Transfusion; chelators
267.
Anti-K and anti-Fya; Enzyme techniques
268.
Malaria; Haiti
269.
Antithetical platelet antigens; GPIIIa
270.
Rh null phenotype; stomatocytes
271.
Plasma products; expiration
272.
Bleeding complications; central line placement
273.
Anti-M; glycophorin A
274.
Apheresis catheter placement; patient management
275.
Cryoprecipitate; minimum factor
276.
Mislabeled Specimen; RBC unit issue
277.
Lewis antibody; first pregnancy
278.
Granulocyte transfusion; graft versus host disease
279.
T cell depletion; engraftment failure
280.
Blood component preparation; order of steps
Special Topics
Immunopathology
281.
Paroxysmal nocturnal hemoglobinuria; Ham's test
282.
Immunofluorescence Lupus Band Test; skin
283.
IgA molecules; placenta
284.
IgA deficiency; Caucasians
285.
Severe renal pathology; autoantibody
286.
Silicone breast implants; autoimmune disease
287.
Bence Jones protein; chemical structure
288.
Anti-mitochondrial antibody; symptoms
289.
Acute-phase reaction; indicator

290.
291.
292.
293.
294.
295.
296.
297.
298.
299.

C-reactive protein; pneumoccocal C-polysaccharide

Acute-phase reaction; electrophoresis
Systemic vasculitis; abnormal serologic test
CREST variant of scleroderma; anti-centromere antibody
HIV disease Monitoring; CD34 enumeration
Acute leukemias; immunophenotypic analysis
Hemoglobin F; replacement assay
Linear deposition of IgG and C3; Bullous pemphigoid
Amyotrophic lateral sclerosis; superoxide dismutase-1 (SOD-1) gene
Huntington's chorea; trinucleotide repeat disorder

Laboratory Administration
300.
Maslow; highest level
301.
Motivation technique; empowerment
302.
Accrediting organization; JCAHO
303.
CLIA waived tests; FDA review
304.
Internet connection; T1
305.
Archive hypertext documents; CD-RW
306.
Retention of laboratory reports; time requirements
307.
Current Procedural Terminology; code for a medical procedure or service
308.
Flow chart; symbol
309.
Medicare Part B reimbursement; pathologist services
310.
Specimen referral; illegal
311.
Laboratory employees; Hepatitis B vaccine
312.
majority of tests; type of laboratory
313.
Medicare; billing notification
Special Techniques
314.
Flow cytometry; lymphocyte scatter
315.
HLA type; disease association
316.
Angioimmunoblastic lymphadenopathy; gene rearrangements
317.
Mantle cell lymphoma; phenotypic marker
318.
Acute myelogenous leukemia; retinoic acid therapy
319.
Anaplastic large cell lymphoma; CD30 positivity and t(2;5) translocation
320.
Synovial sarcoma; t(X;18)(p11;q11)
321.
Fragile X syndrome; trinucleotide expansion disease
322.
Hairy cell leukemia; CD11c, CD22, CD25, and CD103
323.
Myelodysplastic syndromes; chromosome changes
324.
Multiple Endocrine Neoplasia type 2; RET gene
325.
Inherited thrombophilia; factor V Leiden mutation