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Title:
SECTIONAL STUDY
Authors:
DR G BALA SREENIVAS , DR P .GANDAIAH ,
DR VENKATESWARLU N
Institution(s):
MAHABUBNAGAR
Abstract Category:
Infectious Diseases
Methods: This one year cross sectional study was done from JULY 2015 to JUNE 2016 in the
Department of Medicine, SVS MEDICAL COLLEGE& HOSPITAL, Mahabubnagar.A total 50 Patients
presented with malaria infection were investigated for serum lipid profile changes.
Results: Majority of the patients were males (82%) with male to female ratio4.5:1. The mean age was
33.96+/-12.72 years. At presentation all the patients had fever with chills and rigors(100%) while
generalized body pain was noted in 80%and the commonest clinical sign was pallor (40%) systemic
examination revealed, splenomegaly in 40% . Majority (86%) of the patients were positive for
Plasmodium vivax. Thrombocytopenia was noted in 64% of the patients. Serum lipid profile estimation in
these patients revealed that 60% of the patients had low total cholesterol levels(100 to 150mg/dl),56% of
them had low LDL levels with value being less than 50 mg /dl and ,58% of patients had low HDL levels
(<20 mg/dl )whereas 92% of the patients with hypertriglyceridemia (>150mg/dl). Incidentally we found
that patients with low LDL cholesterol level had low platelet count (51.25+29.67: p= 0.035)
Conclusions: Patients with malaria infections may have lipid parameters alteration in terms of
hypocholesterolemia, low HDL, low LDL levels and hypertriglyceridemia.
G.BALA SREENIVAS
Designation
POST GRADUATE
Mobile
9440295744
e-mail:
DRSREENU@GMAIL.COM