Universidad del Este

Sono 240

Patologas del Seno

Rosaliyvette Reynoso
S00982226
Prof. A. Gonzalez
10/20/16

Breast Pathology

1. Fibroadenoma- is a benign tumor, they are usually round with smooth circumcised
margins
Cause-cause is unknown
Symptoms- symptoms are at times painless the patient may feel the lump
Group-happen in all age groups but mostly in young women around the 30s

2. Giant fibroadenoma-is larger than 5cm, not usual for it to reach 8-10cm, will have well
defined borders
Cause-cause is unknown
Symptoms-symptoms may be painful because of size
Group-occurs in adolescence and perimenopause

3. Fibrocystic disease- is used to categorize histologic variations that range from normal to
proliferative growth, fibrocystic change consists of cysts lined by attenuated cells
Cause-the cause is unknown but may be related to hormonal abnormality
Symptoms-the patient may feel little to no pain
Group-occurs in 50% of women

4. Intraductal papilloma- they are benign lesions, central lesions often present nipple
discharge
Cause- occurs in breast ducts as proliferation of ductal epithelium with central with
fibrogandular
Symptoms- usually a high risk lesion they are painless at times
Group-occurs age 30-50

5. Granular cell tumor- is rare, patient present with solitary mass

Cause-derived from perineural cells based on their immunophenotypic and ultrastructual
characteristics
Symptoms-it is a painless mass
Group-occurs in both women and men

6. Phylloides tumor-is rare, the cell grows in a leaf like matter, they tend to grow rapidly
but usually dont spread beyond breast
Cause-the cause is unknown
Symptoms-little to no pain
Group- occurs more in women in their 40s

7. Ductal ectasia-it is a benign breast condition

Cause-Caused by normal breast changes that happen with age and nothing is to worry
about
Symptoms-Some pain will happen because of nipple discharge
Group-Occurs in women near menopause and breast age

8. Fat necrosis-benign breast condition, the lump can form in an area of fatty breast tissue

Cause-occurs when there is damaged of fatty tissues, which can occur following needle
biopsy or breast surgery
Symptoms-at times it is pain free but at times can be tender and have pain
Group-occurs in both men and women

9. Mastitis- is when the ducts under the nipple become infected and inflamed
Cause-can be caused if the patient is a smoker or nipple piercings, which get infected
Symptoms-the patient might have tender breast and bloody discharge from the nipple
Group-can affect women of all ages but more common in younger women

10. Paget disease- is an uncommon breast cancer

Cause-a patient with an early stage of cancer may obtain paget disease
Symptoms-the nipple skin will be red and itchy or may have a burning sensation, the
nipple could be inverted
Group-occurs to less than 5% of women with breast cancer, men may also get the disease
but it is very rare

11. Medullary breast cancer- rare type of breast cancer, it is an invasive cancer
Cause-cause is unknown
Symptoms- no pain is present until surgical or therapeutic procedures occur
Group-can occur at any age but more common in younger women

12. Tubular breast cancer- is an invasive breast cancer; it starts in milk ducts and spreads to
the breast tissue. It got its name because when looked microscopically they appear as
tubes
Cause-the cause is unknown but usually discovered during a breast screening
Symptoms-no pain is present until surgical or therapeutic procedures occur
Group-most common in women over 50

13. Ductal carcinoma in situ- is an early from of breast cancer, the cancer cells have
developed in the milk ducts and remain there not spreading outside the duct
Cause-caused by age of patient or microcalcification
Symptoms-it has no symptoms but the patient may notice a lump and some discharge
Group-both men and women can get DCIS but is more common in women

14. Inflammatory breast cancer- is rare, accounts for 1%-4% of breast cancer, it has its
name because the skin of the breast has a red inflamed appearance
Cause-the appearance is caused by breast cancer cells blocking tiny lymph channels in
the breast tissue and skin
Symptoms-it causes some pain, the breast will be swollen and feel sore
Group-can happen to women and rarely to men

15. Lobular carcinoma in situ-the changes occur in the breast lobules and do not affect the
surrounding tissue, it is not a cancer right away with time it could evolve into a cancer
Cause-conditions where cells lining the lobules of the breast are different from normal
cells

Symptom-does not have symptoms

Group-occurs in women between the age of 40-50

16. Invasive ductal carcinoma- is the most common cancer, it is cancer that has spreaded
from the milk ducts into the breast tissue, with time it can spread into other parts of the
body
Cause-the cause is unknown
Symptom-the patient will feel lumps on their breast, irritation, breast pain and nipple
discharge
Group-can occur at any age but is more common in women over 55

17. Papillary carcinoma- is rare, it usually is a slow growing cancer

Cause-the cause is unknown
Symptom-the will be a change in breast and some nipple discharge it is symptoms less
Group-more common in women

18. Invasive lobular carcinoma- is the second most common breast cancer, is when the
cancer has begun to invade the breast tissue, over time it can spread to the rest of the
body, they from not in a lump but in a line formation
Cause -the cause is unknown
Symptoms-may not cause any symptoms at first then with time the breast will harden
Group-most common in women at any age but occurs more in older women

References

Castro, L. (2016, August 09). Benign breast conditions: Fat necrosis.

Retrieved from https://www.breastcancercare.org.uk/informationsupport/have-i-got-breast-cancer/benign-breast-conditions/fat-necrosis

Chinyama, C. (2013, December 20). Benign Breast Diseases. Retrieved

from https://books.google.com.pr/books?id=Aa3BBAAAQBAJ

DCIS (Ductal Carcinoma In Situ) Explained - Breast Cancer Care. (2016,

June 04). Retrieved from
https://www.breastcancercare.org.uk/information-support/facing-breastcancer/diagnosed-breast-cancer/primary-breast-cancer/ductal-carcinomain-situ-dcis

Lawton, T. (2009, April/May). Breast. Retrieved from

https://books.google.com.pr/books?id=z17R70VGhnsC

LCIS - Lobular Carcinoma In Situ. (2016, February 18). Retrieved from

http://www.breastcancer.org/symptoms/types/lcis

Levie, T. (2016, June). Inflammatory breast cancer | Breast Cancer Care.

Retrieved from https://www.breastcancercare.org.uk/informationsupport/facing-breast-cancer/diagnosed-breast-cancer/primary-breastcancer/inflammatory-breast-cancer

Levie, K. (2016). Periductal mastitis symptoms and treatment - Breast

Cancer Care. Retrieved from
https://www.breastcancercare.org.uk/information-support/have-i-gotbreast-cancer/benign-breast-conditions/periductal-mastitis

Medullary breast cancer. (2016, July 09). Retrieved from

https://www.breastcancercare.org.uk/information-support/facing-breastcancer/diagnosed-breast-cancer/primary-breast-cancer/medullary-breastcancer

Millan, J. (2016). Benign breast conditions: Duct ectasia. Retrieved from

https://www.breastcancercare.org.uk/information-support/have-i-gotbreast-cancer/benign-breast-conditions/duct-ectasia

Morris, E. (2005, April 26). Breast MRI. Retrieved from

https://books.google.com.pr/books?id=5hpBzXTFpB8C

Papillary breast cancer. (2016, June 18). Retrieved from

https://www.breastcancercare.org.uk/information-support/facing-breastcancer/diagnosed-breast-cancer/primary-breast-cancer/papillary-breastcancer.

Pilnik, S. (2003, October 27). Common Breast Lesions. Retrieved from

https://books.google.com.pr/books?id=Xu1ff3CnkZ8C

Schnitt, S. (2012, October 8). Biopsy Interpretation of the Breast.

Retrieved from https://books.google.com.pr/books?id=vIWVFkGBBhUC

Signs and Symptoms of IDC. (2016, February 18). Retrieved from

http://www.breastcancer.org/symptoms/types/idc/symptoms

Signs and Symptoms of ILC. (2016, February 18). Retrieved from

http://www.breastcancer.org/symptoms/types/ilc/symptoms

Smith, T. (2016, July 10). Tubular breast cancer. Retrieved from

https://www.breastcancercare.org.uk/information-support/facing-breastcancer/diagnosed-breast-cancer/primary-breast-cancer/tubular-breastcancer

Walker, L. (2016, April 6). Phyllodes Tumors of the Breast. Retrieved

from http://www.breastcancer.org/symptoms/types/phyllodes

Young, L. (2016, August 01). Symptoms of Paget's disease. Retrieved

from https://www.breastcancercare.org.uk/information-support/facingbreast-cancer/diagnosed-breast-cancer/primary-breast-cancer/pagetsdisease-breast/symptoms