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REFERENCES
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PD Dr. phil. Jenny Rosendahl
Rahel Klatte, M.Sc.
Universittsklinikum Jena
jenny.rosendahl@med.uni-jena.de
Conflict of interest statement
The authors of all contributions declare that no conflict of interest exists.
CLINICAL SNAPSHOT
A 28-Year-Old Man with Impaired Vision
Osler spots and Janeway lesions on the patients fingers and toes at the time of admission.
A 28-year-old man with acutely impaired vision, headache, and fever was referred to the emergency room because of
suspected meningitis. His vital signs on admission were: blood pressure, 110/75 mmHg; heart rate, 125/min; temperature,
38.5C. Physical examination revealed the skin changes shown in the images. Transesophageal echocardiography was
performed without delay and revealed a threadlike vegetation on the aortic valve. The laboratory findings were: WBC,
14 900/L; platelet count, 30 000/L; CRP, 147 mg/L (normal, <5 mg/L). Antibiotic therapy with ampicillin/sulbactam and
gentamicin was initiated as recommended in the pertinent guidelines; blood cultures taken beforehand were positive 24 hours
later for Staphylococcus aureus. The patients further course was complicated by recurrent endocarditis after aortic valve
replacement and by an intracranial hemorrhage extending into the ventricular system, causing hemiplegia. A bicuspid aortic
valve was a predisposing factor for this patients endocarditis. Impaired vision is a rare initial manifestation of endocarditis and
led to the initial misdiagnosis of meningitis in this case. Magnetic resonance imaging of the brain revealed numerous septic
emboli as the cause of the patients neurologic abnormalities.
Dr. med. Peter Korsten, Klinik fr Nephrologie und Rheumatologie, Universittsmedizin Gttingen, peter.korsten@med.uni-goettingen.de
Prof. Dr. med. Sabine Blaschke, Interdisziplinre Notaufnahme, Universittsmedizin Gttingen
Conflict of interest statement
The authors declare that no conflict of interest exists.
Cite this as: Korsten P, Blaschke S: A 28-year-old man with impaired vision. Dtsch Arztebl Int 2016; 113: 662. DOI: 10.3238/arztebl.2016.0662
Translated from the original German by Ethan Taub, M.D.
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