ABSTRACT

Effect Concentration Piper betle L on Growth Candida albicans In Denture plate

Rafika Anggriany1;Chusnul Chotimah*; Muhammad Iqbal**
Faculty of Dentistry, Indonesia Moeslim University, Makassar
Kakatua street No. 27 A, Makssar, Sulawesi Selatan, Indonesia. Kode Pos:
90133
Piper betel L extract is a vine, betel leaves contain essential oils and flavonoids which have
ability of antiseptic, power as antioxidation and fungicides. Aim of this study is to determine the
effect of Piper betle L extract on the growth of Candida albicans which contained in the acrylic
denture. This study takes a sample of the fungus Candida albicans which derived from acrylic
denture plate. Material and Piper betel L is extracted by maceration method using ethanol 96%
test of inhibition is done by using the disc diffusion method using disk blanck, samples were
divided into five groups each group has been given a betel leaf extract with 2%, 4%, 8 %, 10%
and 20% and control while the indicator parameter is measured by attendance zone of inhibition,
then the data were analyzed with SPSS 21. Based on the results of One Way Anova analysis
indicate the value of p = 0.000 (<0.05) that the betel leaf extract can effectively inhibit the
growth of the fungus Candida albicans. Candida albicans fungus cultures size will be decreased
with increasing levels of concentration betel leaf extract
Keywords: Extract Piper betle L, Acrylic denture, Candida albicans