Professional Documents
Culture Documents
Company Background
Superpositioning of a steviol
glycoside with cannabidiol
Leadership
Cannabinoids in Medicine
Cannabinoid Drug
Companies
GW
Zynerba
Vitality
Prodrug Background
Treatment of Inflammatory
Bowel Disease
10
Treatment of Inflammatory
Bowel Disease
Patients
(%)
n=56
Abdominal
pain
83.9%
Abdominal
cramping
76.8%
Joint pain
48.2%
Diarrhea
28.6%
11
Site-Specific Delivery of
THC Enables More Potent Local Effects
Current medications deliver psychoactive THC into the
bloodstream/brain, so low doses are always required
12
The New England Journal of Medicine has written that the rising death
toll has been rivaled in modern history only by that at the peak of the
AIDS epidemic in the early 1990s.
13
Treatment of Narcotic
Bowel Syndrome
14
15
Treatment of Narcotic
Bowel Syndrome
16
Clinical Indications
Status
VB100
VB210
Phase 1 Studies to
initiate in 2017
Additional Drug
Formulations
Preclinical
17
18
Internal Drug
Manufacturing Capacity
19
Platform Technology
Steviol
Cannabinoids
Steviol
Glycosides
Cannabinoid
Glycosides
(Reb A, D, M,
Next-gen Sweetener)
(Cannaboside Prodrugs)
20
Cannabinoid Prodrugs
21
22
Cannabinoid Prodrugs
Intellectual Property
New international patent
filing with PCT covering
compositions of matter for
more than 20 cannabinoid
prodrugs with modified
solubility and stability,
including glycoside prodrugs
of THC, CBD, and CBDV, with
protection that would extend
to 2035 or longer with PTEs
Manufacturing system for
glycosides, geared for lowcost efficient production of
steviol and cannabinoid
glycosides
Company Highlights
of cannabis pharmaceuticals
using a low-cost, low-risk prodrug
strategy
Proprietary glycosylation