Extraction of Active Chemical Constituent of Herbal Medicinal Plant

Using Microwave-Assisted Extraction Technique

...


1.

2.
3.
4.

(model)
1

(isolation)
(purification)

2
Soxhlet extraction

Soxhlet extraction
Soxhlet extraction

2
(Microwave assisted extraction)
3

3 x 102 3 x 105
0.001 1 Far infrared

(FM broadcast radio) 4

2 dipole rotation ionic
conduction dipole

ionic conduction
dipole
dipole rotation 2450 electric component
4.9 x 104

2450 electrical component
2450 electrical component
2


(convection) (conduction) (radiation)
(thermal gradient)

(molecular interaction)

Dissipation factor (tan )

tan
loss factor () dielectric constant ()
5
tan =

( )

dielectric
constant 1

dielectric constant
dissipation factor
superheating




(solid matrix)

dipole rotation 5
1 5

2-

Dielectric constanta
()
20.7
37.5
24.3
1.89
32.6
19.9
78.3

Dissipation factor
(tan ) ( 10-4)
5,555
2,500
6,400
6,700
1,570

b c
(C)
(cP)
56
0.30
82
78
0.69
69
0.30
65
0.54
82
0.30
100
0.89

- (1:1)
a

6.02

5,316

77
52

0.43

20 C, b 101.4 kPa, c 25 C

1. (S/F ratio)




dielectric constant


5
(yield)
tan ether linkages
(soluble fraction)

(reflux) (permeation) (solubilization)

(transparent) 2

6 (volatile oil)

5, 7


6

10:1 30:1 (
)8-14

2.

30

Wang 15 2
30 Ginsenoside Panax ginseng

Guo 12 30 puerarin
Radix puerariae 5.44 180 puerarin
6.05

3. (Microwave power)


Yan 14 50 C 70 C
astragalosides Radix Astragali 70 C
astragalosides


16
4.




(preleaching extraction) 17



5
5.


S/F ratio 5

2
2

Artemisia annua

Artemisinin

60-80

S/F
ratio
(mL/g)
100:1

Taxus baccata

Paclitaxel

95

10:1.5

0.0059

Thea sinensis

Polyphenols
Caffeine
Total
triterpenoid
saponins
Polyphenols

50%

95%

85-90

20:1

90

25:1

30
4
0.968

80%

80

20:1

Puerarin

70%

50%

90

30:1

5.94

18

50

20:1

1.679
0.082
1.159
2.939

Ganoderma atrum

Camellia sinensis,
Salvia officinalis,
Achillea millefolium,
Alchemilla vulgaris
Radix puerariae

Cinnamomum zeylanicum, Phenolic

Coriandrum sativum,
compounds
Cuminum cyminum,
Crocus sativus
a

()
(C)

a
(%w/w)
0.73

Misra
3
Talebi
8
Pan
9
Chen
10

Bekdeser
11

Guo
12
Gallo
13

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