Mechanism and How does Hoodia Extracts Work?

Contents
Botanical Basic Information of Hoodia cactus,Hoodia Gordonii.

What is Hoodia Gordonii Cactus and Hoodia Extract?Why we need Hoodia?.

Mechanism and How does Hoodia Extracts Work?.
Hoodia Gordonii Cactus and Hoodia Extract,the new weight loss miracle?.
How Hoodia Cactus Drive Out Obesity.
Processing of Hoodia Gordoni Cactus Extract.
Hoodia Gordonii:Scientific Support.
Benefit of Hoodia Gordonii Cactus and Hoodia Extract?
Administration Guide and Safety of Hoodia Gordonii Cactus.
Hoodia Cactus:Frequently Asked Questions.
Research Update:Hoodia Gordonii or Asclepiad Trichocaulon.

Mechanism and How does Hoodia

Extracts Work?
Hoodia Contains Steroidal glycosides
When scientists were routinely testing Hoodia, they
discovered that Hoodia contains a previously unknown
molecule, which has since been identified as Steroidal
glycosides.
Whole hoodia powder contains variable amounts of fiber,
organic material, antioxidants and biologically active
substances including steroidal glycosides, which appear to
fool the brain into thinking the stomach is full.
Chemical Name: Beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O- methyl-Beta-D-ribohexopyranosyl)oxy]- 14-hydroxy- 12-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]pregn- 5-en-20one.
Beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O- methyl-Beta-D-ribo-hexopyranosyl)oxy]14-hydroxy- 12-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]pregn- 5-en-20-one.
(3Beta,12Beta,14Beta)-3-[(O-6-Deoxy-3-O-methyl-Beta-D-glucopyranosyl-(1->4)-O-2,6-

dideoxy-3-O-methyl-Beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-Beta-D-ribohexopyranosyl)oxy]-14-hydroxy-12-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]pregn-5-en-20-one
Other names: P57;P57AS3.
Chemical formula: C47H74O15 Molecular mass: 879.08 g/mol CAS No: 384329-61-7

New Constituents Identified from the Hoodia

Chemists identified 10 new C(21)-steroidal derivatives,namely gordonosides A-L were
isolated from a chloroform extract of the aerial parts of Hoodia gordonii.Compounds are
based on 3beta,14beta-dihydroxy-pregn-5-en-17-betaone aglycone.Hoodigosides A-K(111),11 new oxypregnane glycosides and a previously reported oxypregnane glycoside
P57AS3 were isolated from the aerial parts of Hoodia gordonii.The structures of these 12O0beta-tigloyl isoramanone glycosides were determined.A steroidal glycoside with anorectic
activity in animals,termed P57AS3(P57),was isolated from Hoodia gordonii and found to have
homologies to the steroidal core of cardiac
glycosides.
.

How Hoodia Steroidal glycosides

Helps to Reduce Weight
There is a part of your brain, the
hypothalamus. Within that mid-brain there are
nerve cells that sense glucose sugar. When
you eat, blood sugar goes up and these nerve
cells signal that you are full. The Hoodia
Steroidal Glycosides is about 10,000 times as
active as glucose. It goes to the mid-brain and actually makes those nerve cells react as if
you were full. But you have not eaten. Nor do you want to.
Hoodia Steroidal glycosides works by mimicking the effect that glucose has on nerve cells in
the brain : in effect fooling the body into thinking it is full, even when it is not, thus curbing the
appetite.
The irony that some of the world's most overfed people may benefit from some of the
hungriest was not lost on the San.
"At first people here were a bit shocked," said Nigel Crawhall, a professor at the South
African San Institute and a campaigner for the rights of indigenous tribes. "Why would
anybody want to lose weight by eating the hoodia plant? Because it's meant for when you're
traveling across the desert and you don't have
enough to eat. So we thought it was a bit
weird."
hoodia extracts kills the appetite and attacks
obesity, is organic with no synthetic or artificial
appetite control agents, has no known side
effects, contains a miracle molecule (up to
100000 times more powerful than glucose) that
fools the brain into believing you are full, and
even stops you from thinking about food. But it
actually does MORE...

Since Hoodia Contains a powerful molecule that fools your brain into believing you are full,
experts consider that, when properly developed and tested, Hoodia weight loss formula may
be a solution to the obesity epidemic.
Most human users claim that it produces an immediate effect upon eating - an upliftment in
mood immediately, followed by a complete satiation of the appetite. After eating Hoodia one
simply doesn't feel like eating a thing. You might want to eat because you know its lunchtime,
but there's simply no desire to chew and swallow your food.
According to some users of fresh Hoodia it is a wonderful plant to eat. They say it tastes
sweet and bitter, but others say the taste needs to be improved to be as edible to humans as
cucumbers.Though clinical trials on aphrodisiac qualities of the plant have not been
conducted, the reports and testimonials of users are very persistent. Besides alleviating
hunger and thirst, Hoodia also provides a state of alertness but without the jittery feeling
produced by the current Western diet remedy of ephedra stacked with caffeine and aspirin.
Thus it is an ideal choice for days' long hunts where prey is tracked over endless miles and
there is no food available. It is equally useful for people in urban and western societies, when
people are either bored or stressed and overeat to ease the boredom or the stress.
The steroidal glycosides that help Hoodia gordonii to survive by curbing the appetite of
grazers, will have to be present in Hoodia macrantha and ruschii and currari and several
others - where the species differ just by the average height, or how many ribs they have, or
the color of the flowers. According to one contributor to a
gardening forum, Hoodia macrantha cannot be distinguished
from Hoodia gordonii until the plants are some 5 years old and
they start to flower.

Clinical Diet and Weight Loss Trials of Hoodia

The first animal trials for Hoodia were on rats. Rats will eat
literally anything. But after being given Hoodia they stopped
eating completely. When the first human clinical trial was
conducted, a morbidly obese group of people were placed in a
"phase 1 unit", a place like a prison. All the volunteers could do
all day was read papers, watch television, and eat. Half were
given Hoodia, half placebo. Fifteen days later, the Hoodia group had reduced their calorie
intake by 1000 a day. These remarkable weight control results are the reason why scientists
see Hoodia weight loss pills as a potential answer to obesity and severe overweight.