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ABSTRACT
This study compares associations between
demographic proles, long bone lengths, bone mineral content, and frequencies of stress indicators in the preadult
populations of two medieval skeletal assemblages from
Denmark. One is from a leprosarium, and thus probably
represents a disadvantaged group (Nstved). The other
comes from a normal, and in comparison rather privileged,
medieval community (belholt). Previous studies of the
adult population indicated differences between the two
skeletal collections with regard to mortality, dental size,
and metabolic and specic infectious disease. The two
samples were analyzed against the view known as the
osteological paradox (Wood et al. [1992] Curr. Anthropol.
33:343370), according to which skeletons displaying pathological modication are likely to represent the
healthier individuals of a population, whereas those without lesions would have died without acquiring modications as a result of a depressed immune response. Results
reveal that older age groups among the preadults from
Nstved are shorter and have less bone mineral content
than their peers from belholt. On average, the Nstved
children have a higher prevalence of stress indicators, and
in some cases display skeletal signs of leprosy. This is
likely a result of the combination of compromised health
and social disadvantage, thus supporting a more traditional interpretation. The study provides insights into the
health of children from two different biocultural settings
of medieval Danish society and illustrates the importance
of comparing samples of single age groups. Am J Phys
Anthropol 128:734746, 2005. V 2005 Wiley-Liss, Inc.
C
V
735
MATERIALS
The morbidity and mortality proles of 259 preadult
skeletons from later medieval Sjlland (Zealand) in Denmark were compared. The rst sample comprised 76 preadult skeletons interred in the cemetery connected to St.
Georges Hospital at Aaderup, Nstved (total number
650), one of 31 leprosaria established in Denmark in the
later medieval period (AD 12501550). The second comprised 183 preadults from the cemetery connected to the
Augustinian monastery at belholt between AD 1175
1550 (total number 756). Both sites are contemporane-
736
P. BENNIKE ET AL.
ous and, being only 150 km apart, from the same geographical area.
Mller Christensen excavated the skeletons at belholt
from 19351965 and uncovered burials within the cloister
ambulatory and garth (Bennike, 2002). The adult skeletons, 60% males and 40% females, together with the 183
children, suggested that some individuals were the married servants of the monastic community and their offspring. Further burials in the nave of the church and the
churchyard to the northwest of the monastery represented
monks and privileged lay persons (Mller Christensen,
1982). Thus, those buried in the cemetery probably represent children of farmers connected to and employed by the
monastery, pupils, and the children of parents who could
afford to have them buried within the foundations. This is
supported by the fact that the age distribution at
belholt is very similar to that of other medieval cemeteries in Denmark.
The discoveries at belholt prompted the excavation of
the cemetery at Nstved (19481968). The hospital at
Nstved was rst mentioned in AD 1261 and is known to
have functioned solely as a leprosarium until AD 1542,
when the Ribe Recess ordered all leprosy hospitals in Denmark to be disestablished and patients to be admitted to
larger general hospitals. The socioeconomic status of those
interred at Nstved would have varied, as inmates were
admitted to the hospital from the town of Nstved and
the surrounding area (Mller Christensen, 1961; Andersen, 1969).
Documentary evidence suggests that the Danish medieval community could recognize the classic signs of leprosy
as most of the documents describe the classic facial
changes (Andersen, 1991). In fact, no clear evidence of leprosy was found in over 300 skeletons excavated from an
almshouse (or Helligandshus) in the center of Nstved
(AD 14001800) (Macey, 1996) or in 60 skeletons of a mass
grave nearby dated to the 14th century (Bennike, 2000).
However, in a study of Danish and Swedish medieval skeletons based on a number of specic and nonspecic criteria used for calculation of specicity and sensitivity of the
diagnosis of leprosy, Boldsen (2001) claimed that a high
proportion of the rural Danish population was infected
with leprosy in the 13th century. This conclusion still has
to be proven.
The preadults at Nstved may have entered the sample
in a number of ways. Firstly, children may have been
admitted to the hospital when they presented soft-tissue
lesions associated with leprosy. Today, some children born
to parents with lepromatous leprosy normally develop
clinical signs of the disease by age 5 years (Melsom et al.,
1982; Lewis, 2002c). Richards (1977) cited many cases of
children being examined and admitted to leprosaria in his
study of the disease in Scandinavia, and it was not
unusual to separate the child from its parents. However,
today, infants displaying single leprous lesions are often
overlooked if they are concealed by clothing or ignored by
the mother, and the lesions may heal spontaneously (Lara
and Nolasco, 1956), only to recur at a stressful time during the childs development, e.g., during puberty. Therefore, it is unlikely that the youngest preadults in this sample (02.5 years) were admitted to the hospital diagnosed
with leprosy; yet congenital contraction of the disease cannot be ruled out.
There were equal numbers of male and female skeletons, and some children may have accompanied their
infected parent or parents into the hospital if they were
suspected of being contaminated or, more likely, to pre-
METHODS
Age at death
Data from preadult skeletal material are widely
believed to represent the most demographically variable
and sensitive barometer of biocultural change (Van
Gerven and Armelagos, 1983; Roth, 1992). Patterns of infant and child mortality were shown to have a profound
effect on the crude death rates of a population and, when
coupled with evidence of childhood morbidity, have become
accepted as a measure of population tness and an indicator
of fertility (Mensforth et al., 1978). Although the differential
preservation of fragile preadult skeletons, and selective burial due to cultural factors, may present a serious problem
with underrepresentation, preadult data are relatively free
from the problems of age assignment that plague paleodemographic studies based on adult skeletons. Age estimates
of preadult skeletons are derived using age-specic markers
of growth and maturation. The timing and outcome of these
events are thought to be tentatively linked to a genetic blueprint, as opposed to the degenerative age determinants of
adulthood (Rallison, 1986). For this reason, preadult skeletons allow for more precise skeletal age estimation than is
possible for adults.
Growth studies on modern populations showed that
dental development, characterized by tooth formation
and eruption, is less sensitive to environmental inuences such as malnutrition and infection, and is more
genetically controlled than skeletal maturation and size
(Schour and Massler, 1940; Acheson, 1959; Stini, 1985;
Eveleth, 1986). Dental development is believed to be the
most accurate indicator of age-at-death on the preadult
skeleton (Lewis and Garn, 1960; Smith, 1991, Hillson,
2000).
The age distribution of any given skeletal sample is
determined by the mortality and fertility distribution, and
therefore, growth patterns determined from nonsurvivors
may not provide a true reection of the growth pattern of
surviving individuals in an age group (Johnston, 1962; Van
Gerven and Armelagos, 1983; Jantz and Owsley, 1984;
Saunders and Hoppa, 1993; Wood et al., 1992). On the other
Nstved
Age
Mean
SD
Mean
SD
<2.5
2.66.5
6.610.5
10.614.5
14.620.0
43
57
35
17
9
1.17
4.73
8.86
12.20
16.61
0.71
1.13
1.12
0.99
1.87
14
11
17
11
20
1.32
4.98
8.95
12.04
17.62
0.59
0.79
1.20
0.99
2.94
161
6.19
73
9.49
Total mean
737
738
P. BENNIKE ET AL.
RESULTS
Age distribution
In order to assess whether the preadult age distribution at belholt was attritional, and thus comparable to
other contemporary Danish populations, a comparison
was made with a sample of preadult skeletons (n 252)
from a completely excavated medieval rural cemetery at
Tirup (Kieffer Olsen, 1993). Despite a slight difference in
the ranges of age groups, the demographic pattern at
belholt was similar to that of Tirup. There were 60%
and 61% of preadults between 06.5 years at Tirup and
belholt, respectively, with 33% of the sample making up
children between 6.614.5 years, and 6% in the 14.6
20.0-year age categories, with a similar distribution at
both sites. This similarity in age distribution with a normal medieval cemetery seems to indicate that the preadult skeletons at belholt were not a special, selected
group, e.g., one derived from the hospital section of the
monastery. Contrary to this pattern, we found that when
the mortality proles of Nstved and belholt were compared, the two populations had signicantly different distributions in all age groups (2 28.3, df 4, P < 0.01)
(Fig. 1). For example, at Nstved, a signicantly lower
number of individuals was in the 2.66.5-year age group
(2 9.5, P < 0.01), representing only 15% of the total
sample (belholt, 35 %), and a signicantly higher number of 14.620.0-year-olds (2 21.7, P < 0.01), accounting for 27% of the Nstved population (Table 1). Calculations of average age in each age group were rather similar.
739
DISCUSSION
Is it logical to assume that a group of skeletons displaying pathological lesions and other stress indicators represent the disadvantaged of the society from which they
were derived? Wood et al. (1992) argued that this basic
assumption, commonly used to measure past population
morbidity, is paradoxical. In order to display a stress indicator such as enamel hypoplasia or cribra orbitalia, it is
necessary to recover from the stress that resulted in a cessation of growth (as these lesions only become visible
when normal growth is resumed), or some kind of longstanding condition has to be present. Thus it follows that
only those with a strong immune system and perhaps cultural advantages are likely to survive episodes of stress.
In fact, should not weaker or culturally disadvantaged
individuals enter the mortality sample with no or fewer
skeletal markers of stress and disease because of their
inability to recover from an episode of stress? When all
preadults were combined in each of the two samples, this
assumption could not be conrmed because the less
advantaged group from the leprosy cemetery displayed
more stress-related skeletal modications throughout
(Fig. 3). However, when the various age groups of the two
samples were compared separately, a much more complex
pattern emerged (Table 5) that demonstrates the importance of subdividing a sample into age groups in comparative studies. Contrasting the groups with and without
skeletal stress indicators revealed higher average ages of
those with lesions than those without, except for endocranial lesions. Thus, at least in terms of longevity, yet contra
other parameters, overcoming episodes of stress does
mean surviving them by a measurable margin, which
lends some support to Wood et al. (1992).
In order to assess those most at risk from stress, it is
important to be aware of the environmental and cultural
740
P. BENNIKE ET AL.
TABLE 2. Diaphyseal lengths for long bones (mm)
Diaphyseal lengths (mm)
Humerus
Age (years)
belholt
02.5
2.66.5
6.610.5
10.614.5
14.620.0
26
42
23
9
6
Total
95.8
159.0
208.3
255.1
302.5
6 19.9
6 21.6
621.2
6 27.9
6 24.4
Femur
Range
75.9115.7
137.4180.6
187.1229.5
227.2283.0
278.1326.9
24
39
23
8
5
106
Nstved
02.5
2.66.5
6.610.5
10.614.5
14.620.0
6
6
12
8
13
Total
45
Mean
Tibia
Mean
Range
6
6
6
6
6
82.5144.7
179.5245.1
264.3322.6
319.4399.2
387.3449.9
16
31
20
9
3
113.6
212.3
293.9
359.3
418.6
31.1
32.8
29.6
39.9
31.3
99
99.6
140.8
209.4
228.5
275.6
6
6
6
6
6
13.6
36.9
15.4
24.2
29.6
86.0113.2
103.9177.7
194.0224.8
204.3252.7
246.0305.2
5
4
7
7
10
Mean
Range
96.5
169.9
225.4
292.4
375.0
6
6
6
6
6
24.3
22.6
22.9
33.3
22.6
72.2120.8
147.3192.5
202.5248.3
259.1325.7
352.4397.6
97.5
174.0
235.0
261.0
315.0
6
6
6
6
6
16.0
33.2
16.4
20.4
24.3*
81.5113.5
140.8207.2
218.6251.4
240.6281.4
290.7339.3
79
114.8
224.5
299.7
330.4
380.9
6
6
6
6
6
28.7
39.8
20.7
26.5
29.3*
86.1143.5
184.7264.3
279.0320.4
303.9356.9
351.6410.2
33
3
4
6
6
7
26
belholt
02.5
2.66.5
6.610.5
10.614.5
14.620.0
25
38
22
9
6
Total
factors that may buffer or expose the population to physiological disruption. Goodman (1993, p. 284) argued that
evidence from developing countries refutes the idea of the
healthiest individuals having more stress indicators and
Humerus
Mean and SD
0.26
0.64
0.94
1.37
1.85
6
6
6
6
6
0.28
0.23
0.16
0.36
0.79
100
Nstved
02.5
2.66.5
6.610.5
10.614.5
14.620.0
6
5
12
7
13
Total
43
N
24
37
23
8
4
Femur
Mean and SD
0.40
1.04
1.74
2.65
3.56
6
6
6
6
6
0.17
0.29
0.35
0.67
1.64
0.37
0.91
1.91
1.91
2.68
6
6
6
6
6
0.11
0.47
0.28
0.27
0.84
96
0.25
0.55
1.09
1.12
1.39
6
6
6
6
6
0.05
0.28
0.18
0.20
0.46
6
4
7
7
10
34
states: I know of no situation in which a clearly advantaged group, living or past, has more hypoplasia than a
disadvantaged group. He suggested that by taking the
mean age-at-death, the weakest individuals would be
identied as those who died at an earlier age. Although
stress indicators are generally unrelated to the nal cause
of death, the process causing the lesion may have left the
individual more susceptible. Therefore, individuals with
stress indicators may have been prone to die at an earlier
age, something that Saunders and Hoppa (1993) termed
selective mortality. Individuals with certain stress indicators on their skeletons should be entering the mortality
record earlier than those who do not display the lesions.
At belholt, the mortality curve followed a pattern similar to that of rural Tirup, with a high number of infant
deaths and mortality decreasing as children reach adolescence. Here, preadults represent 24% of the total sample,
whereas at Nstved, preadults represent only 12% of the
total sample, and mortality rates increase with age. In
contrast, the group of preadults represented most at
Nstved is between 14.620.0 years of age (27%). This
age distribution cannot be considered an accurate representation of the living population from which the sample
was derived, because normally only sick individuals were
selected for admission, and due to the incubation period of
741
742
24 (13)*
54
(1)
(0)
(2)
(3)
(7)
8
0
15
23
54
8
8
12
8
18
17 (11)
64
(6)
(4)
(1)
(0)
(0)
54
36
9
0
0
13
10
6
8
17
%A, percentage affected of total individuals observed; %b, percentage affected in each age group.
Signicantly higher at Nstved compared to belholt (2, P 0.005).
1
60 (36)
60
Total
35 (14)
39
42 (23)*
55
(2)
(0)
(9)
(5)
(7)
9
0
39
22
30
10
7
12
9
17
19
19
17
17
28
13
10
15
7
15
Nstved
02.5
2.66.5
6.610.5
10.614.5
14.620.0
53 (57)
108
Total
(7)
(7)
(6)
(6)
(10)
54*
70
40
86
67
123
17 (21)
20
0
75
75
56
(2)
(1)
(2)
(2)
(7)
14
7
14
14
50
8 (7)
88
7
5
9
7
11
28
20
22
28
64
112
8 (9)
46
40*
6
0
0
8.5 (7)
82
12
0
17
37
39
0
0
20
27
0
(0)
(0)
(4)
(3)
(0)
0
0
57
43
0
11
36
20
11
4
77
22
0
0
0
25
45
23
12
7
0
8
19
50
0
(0)
(3)
(2)
(2)
(0)
0
3
2
50
0
19
37
21
5
3
0
0
35
44
28
(0)
(0)
(11)
(8)
(2)
19
48
31
18
7
21
58
64
92
60
(6)
(21)
(16)
(11)
(3)
29
37
25
12
5
belholt
02.5
2.66.5
6.610.5
10.614.5
14.620.0
10
37
28
19
5
%b
Age (years)
%A (N)
0
0
52
38
9
%b
%A (N)
(7)
(2)
(0)
(0)
(0)
28
4
0
0
0
%A (N)
%b
%A (N)
N with
sinuses
%A (N)
Periostitis
%b
Endocranial lesions
N with
skulls
N with
tibiae
N with
teeth
Enamel hypoplasias
Cribra orbitalia
N with
orbits
Maxillary sinusitis
%b
P. BENNIKE ET AL.
adults at belholt. It may be that in order to develop cribra orbitalia, a threshold level of health-associated factors
(such as infectious diseases or nutrirional deciencies)
needs to be reached. Despite the lack of a signicant peak
in cribra orbitalia in the preadult sample at Nstved, the
frequency of this lesion is still higher than at belholt. At
Nstved, 61% of preadults have cribra orbitalia, compared to 54% at belholt. The similar pattern of cribra
orbitalia of the preadult and adult population of Nstved
may reect the same pathogen load and hygienic and
nutritional factors, while the much lower prevalence in
adults at belholt is thought to represent the expected
distribution, with the presence of most cribra orbitalia in
the preadult group compared to adults (Stuart-Macadam,
1991).
The absence of rhinomaxillary changes in the majority
of Nstved preadults does not necessarily conrm that
they were free from leprosy. While they may have suffered
from leprosy at the lower end of the immunity scale, the
youngest individuals may never have developed leprosy.
Although there is evidence of lepromatous leprosy in 3 of
23 individuals from the 6.610.5-year age group, their
numbers are probably too small for any differences to
affect the BMC and long bone length curves (Fig. 3). It is
unlikely that the youngest members of the sample (06.5
year) entered the site by virtue of having leprosy, which
743
TABLE 5. Mean ages at death for individuals with and without stress indicators
With
Without
Stress indicator
Mean
SD
Mean
SD
Difference
(years)
belholt
Cribra orbitalia
Enamel hypoplasia
Periostitis
Endocranial lesions
Sinusitis
7.62
10.8
8.1
1.62
8.0
3.69
2.53
3.03
0.77
3.49
4.79
6.27
5.6
6.8
5.57
4.4
4.06
4.22
4.34
4.24
2.8
4.5**
2.5
5.1*
2.4*
Nstved
Cribra orbitalia
Enamel hypoplasia
Periostitis
Endocranial lesions
Sinusitis
Rhinomaxillary syndrome
9.91
12.7
13.8
3.4
12.45
14.4
6.28
5.03
5.48
3.02
6.52
4.29
9.3
9.16
9.83
10.9
9.27
8.89
6.57
6.21
5.86
5.89
5.16
5.49
0.6
6.5
3.9
7.5*
3.1
5.5
Statics
(KolmogorovSmimov)
K 2.0
K 1.78
K 1.43
K 1.84
K, Kolmogorov-Smimov.
Signicant at P < 0.05.
**
CONCLUSIONS
Compared with children interred at the monastery site
of belholt, those from the leprosarium at Nstved can
be considered socially disadvantaged and suffering from
compromised health. They displayed higher frequencies of
stress indicators, which is likely an illustration of the
higher exposure to risk and greater susceptibility of these
individuals to infection and malnutrition.
744
P. BENNIKE ET AL.
study shows that it is imperative to be aware of the cultural, historical, and economic context from which a population is derived before the morbidity and mortality patterns of a past society can be reconstructed.
This becomes evident, in particular, when single age
groups rather than bulk categories are examined. While
the combined preadult samples create patterns that favor
traditional views on the meaning of skeletal modications,
only a differential analysis of single age groups reveals the
paradoxical relationship of health, morbidity, and osseous
manifestations that is advocated as typical of skeletal
assemblages. Thus the characteristic distribution of stressrelated skeletal modications across various preadult age
groups lends itself to a biocultural analysis that is able to
identify the more subtle effects of social disadvantage and
compromised health.
ACKNOWLEDGMENTS
The research was funded by grant ERBCHRXCT
930193 to P.B. under EU Program Human Capital and
Mobility and carried out at the Museum of Medical History and Laboratory of Biological Anthropology, University of Copenhagen, Denmark. We are most grateful to
Inger Kjr,Verner Alexandersen and Birgitte Sejersen for
helpful discussions.
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