JBCS

ANOS
ISSN 0103-5053

Journal of the Brazilian Chemical Society Vol. 28, No. 4, April, 2017

Cover Picture

Polymers play a key role in defining the size, morphology and, crystal structure of calcium carbonate particles synthesized
by mixing solutions of inorganic salts. Whilst this is a much cheaper and sustainable method than CO2 gas diffusion, it leads
to small, spherical, and homogeneous particles upon pinpoint choice of the polymer. Details are presented in the Article
Synthesis of Submicrometer Calcium Carbonate Particles from Inorganic Salts Using Linear Polymers as Crystallization
Modifiers by Sara E. Facchinetto, Tanize Bortolotto, Gabrielly E. Neumann, Jean C. B. Vieira, Bryan B. de Menezes, Cristiano
Giacomelli and Vanessa Schmidt on page 547.

Contents

Articles
521 MALDI Imaging Mass Spectrometry of Fresh Water
Cyanobacteria: Spatial Distribution of Toxins and Other
Metabolites
Beatriz B. Sandonato, Vanessa G. Santos, Milena F. Luizete,
Joo L. Bronzel Jr., Marcos N. Eberlin and
Humberto M. S. Milagre

Graphical Abstract
Spatial distribution of toxins and other metabolites of fresh water
cyanobacteria by matrix-assisted laser desorption ionization imaging
mass spectrometry (MALDI-IMS).
iv J. Braz. Chem. Soc.

529 A Sensitive Voltammetric Determination of Anti-Parkinson

Drug Pramipexole Using Titanium Dioxide Nanoparticles
Modified Carbon Paste Electrode
Seyed Karim Hassaninejad-Darzi and Farshad Shajie

Graphical Abstract
A sensor based on titanium dioxide nanoparticles modified carbon paste
electrode (TiO2NPs/CPE) was developed for electrocatalytic oxidation of
pramipexole in pharmaceutical formulations and biological samples in
the phosphate solution at pH 5.0.

540 A Green Extraction of Trace Iodine in Table Salts, Vegetables,

and Food Products Prior to Analysis by Inductively Coupled
Plasma Optical Emission Spectrometry
Nunticha Limchoowong, Phitchan Sricharoen, Suchila
Techawongstien, SupalakKongsri and Saksit Chanthai

Graphical Abstract
Green and efficient ultrasound assisted extraction of iodine from food
products was obtained. Deionized water was used as an extraction
solvent under ultrasonic-assisted extraction (UAE) within 5 min. High
recovery of all samples verified good extraction performance.

547 Synthesis of Submicrometer Calcium Carbonate Particles

from Inorganic Salts Using Linear Polymers as Crystallization
Modifiers
Sara E. Facchinetto, Tanize Bortolotto, Gabrielly E. Neumann,
Jean C. B. Vieira, BryanB. de Menezes, Cristiano Giacomelli
and Vanessa Schmidt

Graphical Abstract
Instead of the typical crystallization of CaCO3 into large
calcite crystals, very small uniform spherical particles
were formed upon addition of polymers.

557 Anodic Oxidation of Sulfide to Sulfate: Effect of the Current

Density on the ProcessKinetics
Paulo C. Caliari, Maria J. Pacheco, Lurdes F. Ciraco and
Ana M. C. Lopes

Graphical Abstract
S2- was oxidized to SO42- at a boron-doped diamond (BDD) anode. The
oxidation occurs with the formation of other intermediate sulfur species,
mainly at low applied current intensity.
Vol. 28, No. 4, 2017 v

567 Computational Study of Electronic Effects from -Substituents

on the Tautomerism of Naphthazarin Derivatives
Fbio S. Grasel, Gabriel O. Castanho, Luiz A. M. Fontoura and
SI online Paulo A. Netz

Graphical Abstract
In this work, computational calculation methods were applied to study
the interconversion between tautomers of several naphthazarin and
5-amino-8-hydroxy-1,4-naphthoquinone -substituted derivatives bearing
electron-donor or electron-withdrawing groups.

575 Central Composite Design to Optimizate the Derivatization

Procedure for Analysis of Biogenic Amines by HPLC-UV
ngela K. Argotty Salazar and Juan J. Lozada Castro

Graphical Abstract
A methodology for biogenic amines derivatization was optimized by
experimental design. The optimal conditions were: 15 L of derivatizing
reagent, 20 C of temperature and 40 min of reaction.

582 Non-Synergistic UV-A Photocatalytic Degradation of

Estrogens by Nano-TiO2 Supported on Activated Carbon
Suzamar M. C. Rosa, Arlene B. S. Nossol, Edson Nossol,
SI online Aldo J. G. Zarbin and PatricioG. Peralta-Zamora

Graphical Abstract
Synergy effect in the photocatalytic degradation of organic substrates by
TiO2/activated carbon nanocomposites.

589 Effect of Sulfamic Acid on 1,3-Dipolar Cycloaddition

Reaction: MechanisticStudiesand Synthesis of 4-Aryl-NH-
1,2,3-triazoles from Nitroolefins
SI online Pankaj Sharma, Niggula P. Kumar, Kishna R. Senwar, Oscar
Forero-Doria, FabianeM. Nachtigall, Leonardo S. Santos and
Nagula Shankaraiah

Graphical Abstract
A facile and new metal-free 1,3-dipolar cycloaddition reaction for
the synthesis of 4-aryl-NH-1,2,3-triazoles from nitroolefins and NaN3
employing NH2SO3H has been developed. The key intermediates
associated with this transformation have been characterized by on line
monitoring of the reaction by using ESI-MS/MS.
vi J. Braz. Chem. Soc.

598 Warmingiins A and B, Two New Dimeric Naphthoquinone

Derivatives from Sinningia warmingii (Gesneriaceae)
Vanessa Winiewski, Maria Helena Verdan, Marcos A. Ribeiro,
SI online Alvaro J. HernandezTasco, Marcos J. Salvador and
Maria Elida A. Stefanello

Graphical Abstract
Two new dimeric naphthoquinone derivatives, warmingiins A and B, were
isolated from the tubers of Sinningia warmingii.

603 Distribution and Sources of Aliphatic and Polycyclic Aromatic

Hydrocarbons in Surface Sediments of Itaja-Au Estuarine
System in Brazil
SI online Morgana Frena, Giovana A. Bataglion, Sara S. Sandini, Katia
N. Kuroshima, Marcos N. Eberlin and Luiz A. S. Madureira

Graphical Abstract
Aliphatic and polycyclic aromatic hydrocarbons were assessed in surface
sediment samples of Itaja-Au estuarine system, in order to determine
the depositional organic matter source.

615 Simultaneous Determination of Antimalarial Agents by

LC-MS/MS and Its Application to Evaluation of Fixed-Dose
Tablets
Breno M. Marson, Raquel O. Vilhena, Flavia L. D. Pontes,
Mrio S. Piantavini and Roberto Pontarolo

Graphical Abstract
Quality control methods to detect poor-quality medicines and counterfeit
antimalarials are essential. This study presents a rapid and reliable
LC-MS/MS method, successfully applied for evaluating the quality of the
antimalarials artesunate and mefloquine.

622 Production, Purification and Physicochemical Properties of

an ExoPolygalacturonase from Aspergillus niger SW06
Yu-ping Ma, Hui Hao, Zhi-fei Chen, Zhi-wei Zhao,
Shun-hui Chen, Si-wen Sun and Chun-ping Xu

Graphical Abstract
SDS-PAGE of standard proteins (left column), exo-PG (middle
column) and purified PG (right column) from DEAE-Sepharose FF
chromatography. After purification, SDS-PAGE analysis of the purified exo-
polygalacturonase from Aspergillus niger SW06 showed a single band with
a molecular mass of 66.2 kDa.
Vol. 28, No. 4, 2017 vii

629 Identification of Glycoside Compounds from Tobacco by High

Performance Liquid Chromatography/Electrospray Ionization
Linear Ion-Trap Tandem Mass Spectrometry Coupled with
Electrospray Ionization Orbitrap Mass Spectrometry
Chunxiao Jia, Yonghua Zhu, Jinjie Zhang, Jing Yang,
Chunping Xu and DuobinMao
Graphical Abstract
Twenty-two glycoside compounds have been separated from tobacco
after ultrasonic assistant extraction and purified by Amberlite AB-8
column. The structures of the tobacco glycosides were reliably identified
by high performance liquid chromatography electrospray ionization linear
ion-trap tandem mass spectrometry (HPLC-ESI-LIT/MSn) coupled with
electrospray ionization orbitrap mass spectrometry (ESI-Orbitrap-MS).

641 Influence of Textural Properties and Surface Fractal

Dimensions on the Cobalt Adsorption Behavior of Rice Hull
Ash Prepared via Solid Combustion
Norma A. Snchez-Flores, Francisco Granados-Correa and
Silvia Bulbulian

Graphical Abstract
Surface fractal dimensions of rice hull ash samples prepared by
solidcombustion with corresponding Co2+ adsorption.

649 Nanocomposites Based on Cassava Starch and Chitosan-

Modified Clay: PhysicoMechanical Properties and
Biodegradability in Simulated Compost Soil
SI online Gustavo F. Perotti, Thitisilp Kijchavengkul, Rafael A. Auras
and VeraR.L.Constantino

Graphical Abstract
Starch-based material comprising chitosan-modified clay showed a
decrease of decomposition rate in composting test in comparison to
pristine thermoplastic starch.

659 Concentration Profiles of Regulated and Unregulated

Pollutants Emitted from the Combustion of Soybean Biodiesel
and Diesel/Biodiesel Blend Originating of a Diesel Cycle
SI online Engine
Beatriz S. Amaral, Luciana M. B. Ventura, Ariane S. Amaral,
Francisco R. A. Neto and Adriana Gioda

Graphical Abstract
This figure shows the concentration profiles of emitted pollutants in
biofuels and blends from a stationary engine.
viii J. Braz. Chem. Soc.

669 Modification of Vietnam Natural Rubber via Graft

Copolymerization with Styrene
Tran Anh Dung, Nguyen Thi Nhan, Nghiem Thi Thuong,
Phan Trung Nghia, Yoshimasa Yamamoto, Kenichiro Kosugi,
Seiichi Kawahara and Tran Thi Thuy

Graphical Abstract
The graft copolymerization of styrene onto deproteinized natural rubber
has been studied. The core-shell arrangement was obtained in styrene-
deproteinized natural rubber copolymer. This structure resulted in the
outstanding thermal and mechanical properties of graft copolymer.

Short Reports
676 Influence of Water and Ultraviolet Irradiation on the
Induction Period of the Oxidation of Biodiesel
Willian L. G. da Silva, Acacia A. Salomo, Marta M. D. C. Vila
and MatthieuTubino

Graphical Abstract
How light, water and oxygen can affect biodiesel during storage?

681 New Strategies for Molecular Diversification of 2-[Aminoalkyl-

(1H-1,2,3-triazol-1-yl)]-1,4-naphthoquinones Using Click
Chemistry
SI online Ronaldo N. de Oliveira, Mauro G. da Silva, Moara Targino da
Silva, Valentina N. Melo, Wagner O. Valena, Josinete Angela
da Paz and Celso A. Camara

Graphical Abstract
Click-chemistry protocol aims to access molecular diversity based
on two strategies to obtain scaffolds of 2-amino-alkyl substituted
natural and synthetic 1,4-naphthoquinones linked to the 1,2,3-triazole
heterocyclicring.

689 Smartphone for Point-of-Care Quantification of Protein by

Bradford Assay
Camila L. de Camargo, Marcia B. R. Vicentini, Angelo L.
SI online Gobbi, Diego S. T. Martinez and Renato S. Lima

Graphical Abstract
The use of a negatoscope to illuminate the samples was a simple,
lowcost and effective output to suppress the interferences from
externallight.