4/20/2011

DrugInformationResources
TertiaryResources
Drug Information Resources
DrugInformationResources Secondary Resources
SecondaryResources
PrimaryResources
ContinuingProfessionalPharmacyDevelopment
InternetResources
(CPPD)
ConsumerHealthInformation
20April2011
Maguy El Hajj BScPharm PharmD
MaguyElHajj,BScPharm,PharmD
AssistantProfessorandChair
ClinicalPharmacyandPractice
CollegeofPharmacy,
QatarUniversity,Doha,Qatar
MHApril202011

TertiaryResources TertiaryResources
Theyinclude: Advantages:
Textbooks
T tb k Convenience
C i
Compendia Easeofuse
Reviewarticles Completeinformation
Othergeneralinformationsuchasmaybefound
ontheinternet

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

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TertiaryResources TertiaryResources
Drawbacks: Resourceselection:
Lagtimelesscurrentinformation
L ti l ti f ti Practicesetting
P ti tti
Incompleteinformationduetospace Availablefunding
restrictionsandincompleteliteraturesearchby Patientsseen
theauthor Typeofinformationneeded
Possibleerrorsintranscription,humanbias, g q g y
Druginformationrequestcategory
i
incorrectinterpretationofinformationorlackof
ti t t ti fi f ti l k f
expertisebyauthors

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

TertiaryResources TertiaryResources
Request Type Examples ofTertiary Resources
Evaluationoftertiaryliterature: General AHFSDrugInformation,FactsandComparisons,
Doestheauthorhaveappropriateexpertiseto
D th th h i t ti t product
product PDR DRUGDEX
PDR, DRUGDEX,DrugInformationHandbook,
Drug Information Handbook
information USPDIVolumeI,Micromedex,andBritish
publishinthisarea? NationalFormulary(MAJORCOMPENDIA)
Istheinformationlikelytobetimelybasedon Adverse Meylers SideeffectsofDrugsandMajor
effects Compendia
publicationdate?
Compounding Remington: TheScienceandPractice of
Istheinformationsupportedbyappropriate Pharmacy,Merckindex,PracticalGuideto
citations?
it ti ? Contemporary Pharmacy Practice USP/NF
ContemporaryPharmacyPractice,USP/NF,
Martindale:TheCompleteDrugReference,
Doestheresourcecontainrelevantinformation Ansel sPharmaceuticalDosageFormsandDrug
andisfreeofbias? DeliverySystems

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

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TertiaryResources TertiaryResources
Request Type Examples ofTertiary Resources Request Type Examples ofTertiary Resources
Dietary Natural MedicineComprehensiveDatabase, Drugsin MajorCompendia, DrugsinPregnancyand
supplement
supplement Review of Natural Products PDR for herbal
ReviewofNaturalProducts,PDRforherbal Pregnancy and Lactation,andDrugsforPregnantandLactating
Pregnancyand Lactation and Drugs for Pregnant and Lactating
medicine,andHerbalMedicines:AGuidefor Lactation Mothers
HealthCareProfessionals Foreigndrug Martindale:TheCompleteDrugReference,Index
Drugdosing MajorCompendiaandDrugPrescribing inRenal identification Nominum,DRUGDEX,andinternetsearch
Failure engines
Drug MajorCompendia,DrugInteractionFacts, Geriatric MajorCompendia,GeriatricDosage Handbook
interactions Stockleys DrugInteractions dosage andMerckManualofGeriatrics
Drug BasicSkillsinInterpreting LaboratoryData, Investigational FDAwebsite,Clinicaltrials.gov, Manufacturer
laboratory ClinicalGuidetoLaboratoryTests,and drug websites
interference LaboratoryTestHandbook information

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

TertiaryResources TertiaryResources
Request Type Examples ofTertiary Resources Request Type Examples ofTertiary Resources
Incompatibility HandbookofInjectableDrugs,Trissels Stability Therapy Pharmacotherapy:APathophysiologic Approach,
and stability
stability of Compounded Formulations and Remington:
ofCompoundedFormulations,andRemington: recommendat Harrison
HarrisonssPrinciplesofInternalMedicine,
Principles of Internal Medicine
TheScienceand PracticeofPharmacy ion AppliedTherapeutics,andTextbookof
Pediatric MajorCompendia, PediatricDosageHandbook, Therapeutics
dosage andHarrietLaneHandbook Toxicology POISINDEX,Poisoning andToxicologyHandbook,
Pharmaco ClinicalPharmacokinetics,Applied information andClinicalManagementofDrugOverdose
kinetics PharmacokineticsandPharmacodynamics,Basic
ClinicalPharmacokineticsandMajorCompendia
Pharmacology Goodman andGilmans:ThePharmacological
BasisofTherapeutics,BasicandClinical
PharmacologyandPrinciplesofPharmacology

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

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TertiaryResources TertiaryResources
AHFSDrugInformation: DrugFactsandComparisons:
ItcontainsinformationonbothFDAapproved
It t i i f ti b th FDA d Itcontainsinformationorganizedbydrugclass
It t i i f ti i db d l
andofflabeledusesofmedications Therearecomparativemonographsofdrug
Itcontainsinformationaboutdosinginspecial classestohelpdiscerndifferencesbetween
populations agentsofthesameclass
Itcontainssomeinformationabout Itisavailablethrough
compatibilityandstabilityofinjectables
tibilit d t bilit f i j t bl CD ROM d i t
CDROM,andinternetaswell
t ll
Itisavailableaspapertext,asintranet
andPDAversion
Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.
McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

TertiaryResources TertiaryResources
DrugInformationHandbook(DIH): PDR(PhysicianDeskReference):
Itisorganizedinbriefdrugmonographs
It i i di b i fd h Itisacompilationofproductpackageinserts
It i il ti f d t k i t
DataincludesFDAapprovedandofflabeleduse Itincludescontactinformationfor
ofmedications manufacturers,alistofpoisoncontrolcenters
Ithasseveralappendixesprovidingtreatment andsomelimitedtabletidentification
optionsandcomparingagentsinthesameclass Itisaslo availablethroughPDAandonline
Itisalsoavailablethrough http://www.pdrhealth.com/drugs/drugs
CDROM,PDAandinternet index.aspx

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
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TertiaryResources TertiaryResources
Micromedex: DRUGDEXsystem:
Thisisanelectronicdatabaseinside
Thi i l t i d t b i id
Micromedex
ItcontainsinformationaboutFDAapproved
indications,offlabeluses,pharmacokinetic
data,safetyinformationandpharmacology
ItisavailablethroughCDROM,PDAandinternet
It i il bl th h CD ROM PDA d i t t

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006.
MHApril202011 MHApril202011

TertiaryResources TertiaryResources
USPDIVolumesIIIandIII: IndexNominum:InternationalDrugDirectory
VolumeIcontainsinformationforthehealth
V l I t i i f ti f th h lth Itcontainsinformationondrugsavailablein
It t i i f ti d il bl i
careprofessional,organizedintomonographs over140countries
basedonnonproprietarynames Informationisincludedregarding:structure,
VolumeIIcontainsadviceforthelaypersonand therapeuticclassandproprietarynamesof
materialintendedtosupplementcounseling medications
VolumeIIIincludesinformationabout
V l III i l d i f ti b t ItisalsoavailablethroughMicromedex
It i l il bl th h Mi d
therapeuticequivalenceandUSP/NF
requirementsforlabeling,storingandpackaging
drugs
Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.
McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

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TertiaryResources TertiaryResources
Martindale:TheCompleteDrugReference Meyler's SideEffectsofDrugs:
Itincludesinformationondomesticand
It i l d i f ti d ti d Itprovidesacriticalreviewofinternational
It id iti l i fi t ti l
internationaldrugs literatureintheareaofadversedrugevents
Proprietarynamesandmanufacturercontact Adverseeventsareorganizedbydrugnameand
informationareavailablefordifferentcountries thenbyorgansystemwithineachdrug
Someinformationisprovidedaboutherbs,
di
diagnosticagents,andradioactiveagents
ti t d di ti t
Itisavailableasonline,hardcopyandCDROM
ItisalsoavailablethroughMicromedex
Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.
McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

TertiaryResources TertiaryResources
MerckIndex: ReviewofNaturalProducts:
Itincludesdatalikechemicalstructure,
It i l d d t lik h i l t t Itprovidesinformationaboutthechemistry,
It id i f ti b t th h i t
molecularweightandphysicaldataincluding pharmacologyandtoxicologyofnatural
solubility substances
Itisusefulincompounding Asummaryofrelevantclinicaltrialsisalso
Itisalsoavailableasonline, available
CDROMandPDA Itisavailableaslooseleaf,
It i il bl l l f
boundpaper,CDROMandonline

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

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TertiaryResources TertiaryResources
DrugInteractionsFacts: Stockleys Druginteractions:
Itprovidesinformationaboutdrugdrugordrug
It id i f ti b td d d Itcontainsconcisesummariesofdrug
It t i i i fd
foodinteractions interactionswithsupportingreferencecitations
Significanceoftheinteractionandsuggestions ItisalsoavailableinCDROM,printandonline
formanagementarealsoincluded
Itisavailableinbothboundandlooseleaftexts
ItisavailableonlineandasCDROM

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

TertiaryResources TertiaryResources
IDENTIDEX : HandbookonInjectableDrugs:
ItisavailablethroughMicromedex
It i il bl th h Mi d Itincludesinformationregardingthe
It i l d i f ti di th
Ithastheabilitytoindentifytabletsandpills compatibilityandstabilityofvariousparenteral
basedontheimprintcodeselected medications
Itincludesinformationaboutroutesof
administrationandavailablestrengths
ItisalsoavailableasaCDROMandasapocket
It i l il bl CD ROM d k t
handbook

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

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TertiaryResources TertiaryResources
DrugsinPregnancyandLactation: HandbookofNonprescriptionDrugs:anInteractive
Itfocusesextensivelyoninformationavailable
It f t i l i f ti il bl Approach to Selfcare
ApproachtoSelfcare
abouttheuseofmedicationsinpregnantor Itisorganizedbybodysystemfocusingon
lactatingwomen diseasestatesforwhichselfcaremaybeproper
Informationisprovidedaboutcomparative
efficacyofvariousOTCagents,
contraindications for self therapy and drug
contraindicationsforselftherapy,anddrug
interactions

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

TertiaryResources TertiaryResources
AppliedTherapeutics:TheClinicalUseofDrugs Harrison'sPrinciplesofInternalMedicine:
Itincludesinformationaboutdiseasestatesand
It i l d i f ti b t di t t d Itincludesinformationrelatedto
It i l d i f ti l t dt
treatmentoptions pathophysiology,differentialdiagnosisand
Itisintheformofcasesandfollowup diseasemanagement
discussion ItisalsoavailableasPDAandonline
ItcomeswithaCDROM

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
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TertiaryResources TertiaryResources
Pharmacotherapy:APathophysiologic Approach: Poisindex:
Itcontainsinformationaboutdisorders
It t i i f ti b t di d ItisavailableasMicromedex
It i il bl Mi d
includingepidemiology,etiology,presentationof Itprovidesinformationaboutpresentationand
disease,andtreatment treatmentofmanytoxicologysituations
ItisalsoavailableasaCDROM

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

TertiaryResources TertiaryResources
Otherresources: Guidelines:
BritishNationalFormulary(BNF)
B iti h N ti lF l (BNF) Chestguidelines:
Ch t id li
PediatricDosageHandbook http://www.chestnet.org/accp/guidelines
AppliedPharmacokineticsand AHAguidelines:
Pharmacodynamics http://www.heart.org/HEARTORG/
BasicandClinicalPharmacology NCCNguidelines:http://www.nccn.org
GoodmanandGilmans:ThePharmacological IDSApracticeguidelines:
Basisoftherapeutics http://www.idsociety.org

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
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TertiaryResources TertiaryResources
Guidelines: Guidelines:
NationalHeartLungandBloodInstitute
N ti lH tL d Bl d I tit t AmericanDiabetesAssociation:
A i Di b t A i ti
guidelines:http://www.nhlbi.nih.gov/guidelines http://www.diabetes.org
AmericanAcademyofNeurology: AmericanCancerSociety:http://www.cancer.org
http://www.aan.com/go/practice/guidelines
AmericanAcademyofPediatrics:
htt //
http://www.aap.org/ /
AmericanPsychiatricAssociation:
http://www.psych.org
Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.
McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

TertiaryResources SecondaryResources
Reviewarticles:
Itcontainsinformationaboutdisorders
It t i i f ti b t di d It
Itreferstoreferencesthateitherindexor
f t f th t ith i d
includingepidemiology,etiology,presentationof abstracttheprimaryliterature
disease,andtreatment Indexing:providingbibliographiccitation
http://www.uspharmacist.com information
Abstracting:providingabriefsummaryor
d
descriptionoftheinformationfoundinthe
i ti f th i f ti f d i th
article

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
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SecondaryResources SecondaryResources
Examples:
M
Mostareavailableonline
t il bl li Nationalcancerinstitute:
N ti l i tit t
SearchTerm!:AND/OR http://www.cancer.gov
Searchlimitationbylanguage,yearof Cinahl:http://www.cinahl.com
publication,typeofarticle,typeofjournal Cochranedatabaseofsystematicreviews:
http://www.cochrane.org
Embase:http://www.embase.com
Googlescholar:http://scholar.google.com/

MHApril202011 MHApril202011

SecondaryResources PrimaryResources
Examples: Itconsistsofclinicalresearchstudiesand
Lexisnexis:http://www.lexisnexis.com
L i i htt // l i i reports both published and unpublished
reportsbothpublishedandunpublished
Medline:NationalLibraryofMedicine: Notallliteraturepublishedinajournalis
http://www.nlm.nih.gov classifiedasprimaryliterature:e/g:review
articlesandeditorials
Itincludescontrolledtrials,cohortstudies,case
series and case reports
seriesandcasereports

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006.
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PrimaryResources PrimaryResources
Advantages: Drawbacks:
Accesstodetailedinformation
A t d t il d i f ti Misleadingconclusionbasedononetrial
Mi l di l i b d ti l
Morerecentthantertiaryandsecondary Needtohavegoodskillsinliteratureevaluation
Timeneededtoevaluatelargevolumeof
literatureavailable

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

InternetResources ConsumerHealthInformation
Theycanbeusefulforrequestsaboutunusual Examples:
diseases or about marketed OTC products or
diseasesoraboutmarketedOTCproductsor NationalLibraryofMedicine:
N ti l Lib f M di i
dietarysupplementsoraboutrecentnews http://www.medlineplus.gov
Evaluationcriteria: FDA:http://www.fda.gov/cder
Isthesourcecredible? ThomsonHealthCare:
Istheinformationaccurateandrecent? http://www.gettingwell.com
Istheinformationdetailedandreferenced? Merck:http://www.merckhomeedition.com
Isitpossibletoidentifytheauthorsincaseof NationalWomensHealthInformation
questions? Center:http://www.4women.gov
Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded. Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.
McGrawHill;2006. McGrawHill;2006.
MHApril202011 MHApril202011

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ConsumerHealthInformation
Examples:
CentersforDiseaseControlandPrevention:
C t f Di C t l dP ti
http://www.cdc.gov
RxList:http://www.rxlist.com Questions?

Malone,PMosdell K,KierK,Stanovich K.DrugInformation:AGuideforPharmacists.2nded.

McGrawHill;2006.
MHApril202011 MHApril202011

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