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  • Do Schizophrenia and Autism Share The Same Root? Summary

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    Do Schizophrenia and Autism Share the Same Root? Summary The article discusses about children having autism means that their chances of developing schizophrenia later in life are diminished. This was after a study was conducted on children that had deletions on chromosome 23. However, having a deletion at 22q11.2 was actually linked with a 25-fold increase of developing psychotic condition for instance schizophrenia and autism. There are some researchers that have suggested that there is a relatively high number of autism prevalence within the population due to misdiagnosis of the early signs of schizophrenia (Jalbrzikowski et al 3). These findings were published on the Schizophrenia Research which does support an alternate theory which indicates that schizophrenia and autism are considered as independent outcomes in the same genetic syndrome. The lead investigator had indicated that if there were any correlation among the two conditions, then, it can only be a very small with a negligible effect. Another assistant professor Opal Oulsey states that this new finding well contribute towards the clinical guide in the care of these conditions. What can be done is having prenatal testing which will pick the deletion of chromosome 22q11.2 and this will be discussed by clinicians at an early age with the parents about the risk s of both schizophrenia and autism (Daisy 1). However, the period of the 1970’s majority of clinicians are noted to have interchangeably used child onset schizophrenia and autism. It is recognized that these conditions today are considered as being separate though they do have similarities such as the social difficulties that are present in autism are considered to mimic the social withdrawal of schizophrenia. Individuals that have autism are considered as to be more likely diagnosed with a psychotic condition and vice versa. A medical review indicated that there was a prevalence of autism on people that had some type of psychosis and this was higher than in the general population with no clear reasons. A group of scientists maintained that this was so due to people that had psychotic condition being wrongly diagnosed as well as having autism also. This new study in this journal questioned this theory since it did suggest that the same deletion occurred independently leading to both schizophrenia and autism. When the researched after assessing adolescents that had deletion of 22q11.2 syndromes and diagnose with autism, a review after 6 years did found out that a quarter of the individuals that had been diagnosed with autism were also diagnosed with psychotic condition while another third of the participants had developed some form of psychosis (Daisy 1). Though the differences on the two groups was not statistically significant, the results suggested that being diagnosed with autism had actually nothing bearing the psychosis risk on the individuals. These results were in tandem with another study that had been done on 2015 which had found out that individuals with 22q11.2 deletions and had autism did show a different pattern in gene expression when compared with those with schizophrenia. The findings of this research did also fit with the other findings that had been done by another team of Vortman whereby the parents that had 22q11.2 deletion syndrome as well as schizophrenia did recall in their children as early as 4 years. There was also no relationship between the features of autism in childhood with those that are observed in schizophrenia in adulthood (Fiksinski et al. 4). Work Cited Daisy Yuhas, Spectrum. "Do Schizophrenia And Autism Share The Same Root?". Scientific American. N.p., 2017. Web. 28 Mar. 2017. Fiksinski, A.M. et al. "Autism Spectrum And Psychosis Risk In The 22Q11.2 Deletion Syndrome. Findings From A Prospective Longitudinal Study". Schizophrenia Research (2017): n. pag. Web. Jalbrzikowski, Maria et al. "Transcriptome Profiling Of Peripheral Blood In 22Q11.2 Deletion Syndr

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    Do Schizophrenia and Autism Share the Same Root? Summary The article discusses about children having autism means that their chances of developing schizophrenia later in life are diminished. This was after a study was conducted on children that had deletions on chromosome 23. However, having a deletion at 22q11.2 was actually linked with a 25-fold increase of developing psychotic condition for instance schizophrenia and autism. There are some researchers that have suggested that there is a relatively high number of autism prevalence within the population due to misdiagnosis of the early signs of schizophrenia (Jalbrzikowski et al 3). These findings were published on the Schizophrenia Research which does support an alternate theory which indicates that schizophrenia and autism are considered as independent outcomes in the same genetic syndrome. The lead investigator had indicated that if there were any correlation among the two conditions, then, it can only be a very small with a negligible effect. Another assistant professor Opal Oulsey states that this new finding well contribute towards the clinical guide in the care of these conditions. What can be done is having prenatal testing which will pick the deletion of chromosome 22q11.2 and this will be discussed by clinicians at an early age with the parents about the risk s of both schizophrenia and autism (Daisy 1). However, the period of the 1970’s majority of clinicians are noted to have interchangeably used child onset schizophrenia and autism. It is recognized that these conditions today are considered as being separate though they do have similarities such as the social difficulties that are present in autism are considered to mimic the social withdrawal of schizophrenia. Individuals that have autism are considered as to be more likely diagnosed with a psychotic condition and vice versa. A medical review indicated that there was a prevalence of autism on people that had some type of psychosis and this was higher than in the general population with no clear reasons. A group of scientists maintained that this was so due to people that had psychotic condition being wrongly diagnosed as well as having autism also. This new study in this journal questioned this theory since it did suggest that the same deletion occurred independently leading to both schizophrenia and autism. When the researched after assessing adolescents that had deletion of 22q11.2 syndromes and diagnose with autism, a review after 6 years did found out that a quarter of the individuals that had been diagnosed with autism were also diagnosed with psychotic condition while another third of the participants had developed some form of psychosis (Daisy 1). Though the differences on the two groups was not statistically significant, the results suggested that being diagnosed with autism had actually nothing bearing the psychosis risk on the individuals. These results were in tandem with another study that had been done on 2015 which had found out that individuals with 22q11.2 deletions and had autism did show a different pattern in gene expression when compared with those with schizophrenia. The findings of this research did also fit with the other findings that had been done by another team of Vortman whereby the parents that had 22q11.2 deletion syndrome as well as schizophrenia did recall in their children as early as 4 years. There was also no relationship between the features of autism in childhood with those that are observed in schizophrenia in adulthood (Fiksinski et al. 4). Work Cited Daisy Yuhas, Spectrum. "Do Schizophrenia And Autism Share The Same Root?". Scientific American. N.p., 2017. Web. 28 Mar. 2017. Fiksinski, A.M. et al. "Autism Spectrum And Psychosis Risk In The 22Q11.2 Deletion Syndrome. Findings From A Prospective Longitudinal Study". Schizophrenia Research (2017): n. pag. Web. Jalbrzikowski, Maria et al. "Transcriptome Profiling Of Peripheral Blood In 22Q11.2 Deletion Syndr

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    27 views3 pages

    Do Schizophrenia and Autism Share The Same Root? Summary

    Uploaded by

    adams atebe
    Do Schizophrenia and Autism Share the Same Root? Summary The article discusses about children having autism means that their chances of developing schizophrenia later in life are diminished. This was after a study was conducted on children that had deletions on chromosome 23. However, having a deletion at 22q11.2 was actually linked with a 25-fold increase of developing psychotic condition for instance schizophrenia and autism. There are some researchers that have suggested that there is a relatively high number of autism prevalence within the population due to misdiagnosis of the early signs of schizophrenia (Jalbrzikowski et al 3). These findings were published on the Schizophrenia Research which does support an alternate theory which indicates that schizophrenia and autism are considered as independent outcomes in the same genetic syndrome. The lead investigator had indicated that if there were any correlation among the two conditions, then, it can only be a very small with a negligible effect. Another assistant professor Opal Oulsey states that this new finding well contribute towards the clinical guide in the care of these conditions. What can be done is having prenatal testing which will pick the deletion of chromosome 22q11.2 and this will be discussed by clinicians at an early age with the parents about the risk s of both schizophrenia and autism (Daisy 1). However, the period of the 1970’s majority of clinicians are noted to have interchangeably used child onset schizophrenia and autism. It is recognized that these conditions today are considered as being separate though they do have similarities such as the social difficulties that are present in autism are considered to mimic the social withdrawal of schizophrenia. Individuals that have autism are considered as to be more likely diagnosed with a psychotic condition and vice versa. A medical review indicated that there was a prevalence of autism on people that had some type of psychosis and this was higher than in the general population with no clear reasons. A group of scientists maintained that this was so due to people that had psychotic condition being wrongly diagnosed as well as having autism also. This new study in this journal questioned this theory since it did suggest that the same deletion occurred independently leading to both schizophrenia and autism. When the researched after assessing adolescents that had deletion of 22q11.2 syndromes and diagnose with autism, a review after 6 years did found out that a quarter of the individuals that had been diagnosed with autism were also diagnosed with psychotic condition while another third of the participants had developed some form of psychosis (Daisy 1). Though the differences on the two groups was not statistically significant, the results suggested that being diagnosed with autism had actually nothing bearing the psychosis risk on the individuals. These results were in tandem with another study that had been done on 2015 which had found out that individuals with 22q11.2 deletions and had autism did show a different pattern in gene expression when compared with those with schizophrenia. The findings of this research did also fit with the other findings that had been done by another team of Vortman whereby the parents that had 22q11.2 deletion syndrome as well as schizophrenia did recall in their children as early as 4 years. There was also no relationship between the features of autism in childhood with those that are observed in schizophrenia in adulthood (Fiksinski et al. 4). Work Cited Daisy Yuhas, Spectrum. "Do Schizophrenia And Autism Share The Same Root?". Scientific American. N.p., 2017. Web. 28 Mar. 2017. Fiksinski, A.M. et al. "Autism Spectrum And Psychosis Risk In The 22Q11.2 Deletion Syndrome. Findings From A Prospective Longitudinal Study". Schizophrenia Research (2017): n. pag. Web. Jalbrzikowski, Maria et al. "Transcriptome Profiling Of Peripheral Blood In 22Q11.2 Deletion Syndr

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    © All Rights Reserved
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    of 3

    Do Schizophrenia and Autism Share the Same Root?

    Summary

    The article discusses about children having autism means that their chances of developing

    schizophrenia later in life are diminished. This was after a study was conducted on children that

    had deletions on chromosome 23. However, having a deletion at 22q11.2 was actually linked

    with a 25-fold increase of developing psychotic condition for instance schizophrenia and autism.

    There are some researchers that have suggested that there is a relatively high number of autism

    prevalence within the population due to misdiagnosis of the early signs of schizophrenia

    (Jalbrzikowski et al 3).

    These findings were published on the Schizophrenia Research which does support an alternate

    theory which indicates that schizophrenia and autism are considered as independent outcomes in

    the same genetic syndrome. The lead investigator had indicated that if there were any correlation

    among the two conditions, then, it can only be a very small with a negligible effect. Another

    assistant professor Opal Oulsey states that this new finding well contribute towards the clinical

    guide in the care of these conditions. What can be done is having prenatal testing which will pick

    the deletion of chromosome 22q11.2 and this will be discussed by clinicians at an early age with

    the parents about the risk s of both schizophrenia and autism (Daisy 1).

    However, the period of the 1970s majority of clinicians are noted to have interchangeably used

    child onset schizophrenia and autism. It is recognized that these conditions today are considered

    as being separate though they do have similarities such as the social difficulties that are present

    in autism are considered to mimic the social withdrawal of schizophrenia.

    Individuals that have autism are considered as to be more likely diagnosed with a psychotic

    condition and vice versa. A medical review indicated that there was a prevalence of autism on
    people that had some type of psychosis and this was higher than in the general population with

    no clear reasons. A group of scientists maintained that this was so due to people that had

    psychotic condition being wrongly diagnosed as well as having autism also. This new study in

    this journal questioned this theory since it did suggest that the same deletion occurred

    independently leading to both schizophrenia and autism.

    When the researched after assessing adolescents that had deletion of 22q11.2 syndromes and

    diagnose with autism, a review after 6 years did found out that a quarter of the individuals that

    had been diagnosed with autism were also diagnosed with psychotic condition while another

    third of the participants had developed some form of psychosis (Daisy 1). Though the differences

    on the two groups was not statistically significant, the results suggested that being diagnosed

    with autism had actually nothing bearing the psychosis risk on the individuals.

    These results were in tandem with another study that had been done on 2015 which had found

    out that individuals with 22q11.2 deletions and had autism did show a different pattern in gene

    expression when compared with those with schizophrenia. The findings of this research did also

    fit with the other findings that had been done by another team of Vortman whereby the parents

    that had 22q11.2 deletion syndrome as well as schizophrenia did recall in their children as early

    as 4 years. There was also no relationship between the features of autism in childhood with those

    that are observed in schizophrenia in adulthood (Fiksinski et al. 4).

    Work Cited

    Daisy Yuhas, Spectrum. "Do Schizophrenia And Autism Share The Same Root?". Scientific

    American. N.p., 2017. Web. 28 Mar. 2017.


    Fiksinski, A.M. et al. "Autism Spectrum And Psychosis Risk In The 22Q11.2 Deletion

    Syndrome. Findings From A Prospective Longitudinal Study". Schizophrenia

    Research (2017): n. pag. Web.

    Jalbrzikowski, Maria et al. "Transcriptome Profiling Of Peripheral Blood In 22Q11.2 Deletion

    Syndrome Reveals Functional Pathways Related To Psychosis And Autism Spectrum

    Disorder". PLOS ONE 10.7 (2015): e0132542. Web.

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