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HematopoiesisStemcell(hemocrytoblast)myeloid/lymphoid
Becomemacrophage
(muchgreaterthanneutrophil)
o NonhemeplantsMedicalmanagement:
BloodtransfusionasneededAdministerironsupplementIronsupplementOral:
o FerrousSulfategastricirritation
o OralliquidusestrawParenteral:(IronDextran)
PLATELETS(Thrombocytes)
3
150,000450,000mm GranularfragmentsofmegakaryocytePreventbleedingPlatelet
aggregationPlateletadhesion
o ANEMIAo
DISORDEROFTHEBLOOD(RBC)
AdministerthroughZtrack(donotmassage)Donotgivetea,antacid,milkStoolappeardark
CommonSideEffects:Constipation(increase
Myeloido
o Lymphocyte
TLymphocyte(cellmediatedimmunesystem)
BLymphocyte(humoralmediatedimmunesystem)WBC(white
bloodcell)LEUKOCYTE
Myeloid
o WBCNeutrophils(4070%)
Activephagocytes
Eosinophil(14%)Killparasitic
wormsstopchemicalforinflammation
Basophil(01%)Contain
histamine(activateinflammation)
Lymphocyte(2045%)
TLymphocyte
BLymphocyteMonocyte(48%)
Oxyhemoglobin(oxygenconnecttoRBC)brightred
Primaryproblem:decreaseavailabilityofoxygengoingtothetissueorfasthemolysisCommon
manifestationofAnemia:(PWET)
Palloro Oxygenationproblem
Weaknesso DecreaseO2
Easyfatigabilityo DecreaseO2
Tachycardiao Compensation
HematopoiesisStemcell(hemocrytoblast)myeloid/lymphoid
Becomemacrophage
(muchgreaterthanneutrophil)
o NonhemeplantsMedicalmanagement:
BloodtransfusionasneededAdministerironsupplementIronsupplementOral:
o FerrousSulfategastricirritation
o OralliquidusestrawParenteral:(IronDextran)
PLATELETS(Thrombocytes)
3
150,000450,000mm GranularfragmentsofmegakaryocytePreventbleedingPlatelet
aggregationPlateletadhesion
o ANEMIAo
DISORDEROFTHEBLOOD(RBC)
AdministerthroughZtrack(donotmassage)Donotgivetea,antacid,milkStoolappeardark
CommonSideEffects:Constipation(increase
Myeloido
o Lymphocyte
TLymphocyte(cellmediatedimmunesystem)
BLymphocyte(humoralmediatedimmunesystem)WBC(white
bloodcell)LEUKOCYTE
Myeloid
o WBCNeutrophils(4070%)
Activephagocytes
Eosinophil(14%)Killparasitic
wormsstopchemicalforinflammation
Basophil(01%)Contain
histamine(activateinflammation)
Lymphocyte(2045%)
TLymphocyte
BLymphocyteMonocyte(48%)
vBloodtransfusionasneededAdministerironsupplementIronsupplementOral:
o FerrousSulfategastricirritation
o OralliquidusestrawParenteral:(IronDextran)
PLATELETS(Thrombocytes)
3
150,000450,000mm GranularfragmentsofmegakaryocytePreventbleedingPlatelet
aggregationPlateletadhesion
o ANEMIAo
DISORDEROFTHEBLOOD(RBC)
AdministerthroughZtrack(donotmassage)Donotgivetea,antacid,milkStoolappeardark
CommonSideEffects:Constipation(increase
Myeloido
BloodtransfusionasneededAdministerironsupplementIronsupplementOral:
o FerrousSulfategastricirritation
o OralliquidusestrawParenteral:(IronDextran)
PLATELETS(Thrombocytes)
3
150,000450,000mm GranularfragmentsofmegakaryocytePreventbleedingPlatelet
aggregationPlateletadhesion
o ANEMIAo
DISORDEROFTHEBLOOD(RBC)
AdministerthroughZtrack(donotmassage)Donotgivetea,antacid,milkStoolappeardark
CommonSideEffects:Constipation(increase
Myeloido
vv
ticdisorderRadiationandChemical
Theories/CA(cellularaberration)
Failureoftheimmuneresponsetheory
Cellulartransformation&dearrangementCM:
DecreasematureWBC/RBC/plateletBonepain&Arthalgia(paininthejoint
w/outinflammation)HepatoSpleenomegalyAbdominalpainSign&symptomsof
electrolyteimbalance
DXtest:
BonemarrowaspirationPBS(PeripheralBloodSmear)CBC
Medicalmanagement:
ChemotherapyBonemarrowtransplantBT
NI:
BLEEDINGDISORDERDIC(DissimenatedIntravascularCoagulation)
Acquiredthrombotic/Hemorrhagicsyndrome
Abnormalactivationofclotting&fibrolysis
Parnovirus(decreaseredbonemarrow)
Causes:
DX:
CM
TX:
Characteristicbybonemarrowhypoplasiao Immaturebonemarrow
ResulttoPancytopenia(decreaseRBC/WBC/platelet)
CongenitalRadiationMedicationInfection
CBCBonemarrowaspiration
AnemiaLeukopenia(recurrentinfection)Thrombocytopenia
NI:
ticdisorderRadiationandChemical
Theories/CA(cellularaberration)
Failureoftheimmuneresponsetheory
Cellulartransformation&dearrangementCM:
DecreasematureWBC/RBC/plateletBonepain&Arthalgia(paininthejoint
w/outinflammation)HepatoSpleenomegalyAbdominalpainSign&symptomsof
electrolyteimbalance
DXtest:
BonemarrowaspirationPBS(PeripheralBloodSmear)CBC
Medicalmanagement:
ChemotherapyBonemarrowtransplantBT
NI:
BLEEDINGDISORDERDIC(DissimenatedIntravascularCoagulation)
Acquiredthrombotic/Hemorrhagicsyndrome
Abnormalactivationofclotting&fibrolysis
Parnovirus(decreaseredbonemarrow)
Causes:
DX:
CM
TX:
Characteristicbybonemarrowhypoplasiao Immaturebonemarrow
ResulttoPancytopenia(decreaseRBC/WBC/platelet)
CongenitalRadiationMedicationInfection
CBCBonemarrowaspiration
AnemiaLeukopenia(recurrentinfection)Thrombocytopenia
NI:
Oxyhemoglobin(oxygenconnecttoRBC)brightred
Primaryproblem:decreaseavailabilityofoxygengoingtothetissueorfasthemolysisCommon
manifestationofAnemia:(PWET)
Palloro Oxygenationproblem
Weaknesso DecreaseO2
Easyfatigabilityo DecreaseO2
Tachycardiao Compensation
HematopoiesisStemcell(hemocrytoblast)myeloid/lymphoid
Becomemacrophage
(muchgreaterthanneutrophil)
o NonhemeplantsMedicalmanagement:
BloodtransfusionasneededAdministerironsupplementIronsupplementOral:
o FerrousSulfategastricirritation
o OralliquidusestrawParenteral:(IronDextran)
PLATELETS(Thrombocytes)
3
150,000450,000mm GranularfragmentsofmegakaryocytePreventbleedingPlatelet
aggregationPlateletadhesion
o ANEMIAo
DISORDEROFTHEBLOOD(RBC)
AdministerthroughZtrack(donotmassage)Donotgivetea,antacid,milkStoolappeardark
CommonSideEffects:Constipation(increase
Myeloido
o Lymphocyte
TLymphocyte(cellmediatedimmunesystem)
BLymphocyte(humoralmediatedimmunesystem)WBC(white
bloodcell)LEUKOCYTE
Myeloid
o WBCNeutrophils(4070%)
Activephagocytes
Eosinophil(14%)Killparasitic
wormsstopchemicalforinflammation
Basophil(01%)Contain
histamine(activateinflammation)
Lymphocyte(2045%)
TLymphocyte
BLymphocyteMonocyte(48%)
Oxyhemoglobin(oxygenconnecttoRBC)brightred
Primaryproblem:decreaseavailabilityofoxygengoingtothetissueorfasthemolysisCommon
manifestationofAnemia:(PWET)
Palloro Oxygenationproblem
Weaknesso DecreaseO2
Easyfatigabilityo DecreaseO2
Tachycardiao Compensation