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Method: The study design which used is true experimental design by using pre-test and post-
test with control group design on 36 white rats. Rats were divided into 6 groups. Rats were
divided into negative control (A), single dose of Avocado leaves steeping treatment (B), single
dose of Moringa leaves steeping treatment (E), combination treatment 1 (C), combination
treatment 2 (D), group of simvastatin (F). Data were analyzed by Shapiro Wilk test, ANOVA
hypotesis test, and Duncan post-hoc.
Results: ANOVA tests showed significant finding on post-test measurement (p = 0.008), which
means Ha is accepted. Data group analysis of the moringa and avocado leaves steeping
combination treatment showed no significant difference between D, F, and C group. This result
showed that neither avocado and moringa leaves steeping combination dose nor simvastatin dose
are equally srong to increase HDL levels on hyperlipidemia rat model.
Conclusion: The steeping combination of Moringa and Avocado leaves has an effect to
increasing HDL level. The suggested stepping combination is 18 mg / 200gramWeight avocade
leaf and 27 mg / 200gramWeight moringa leaf.