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Name of Drug Dose/Route Classification Mechanism of Indication Side Effect Nursing Responsibility
Action
Generic Name: Psychosis - Haloperidol Acute and Adverse effects Monitor for therapeutic
Haloperidol, adult: psychotherap blocks the chronic CNS:Extrapyramidal effectiveness. Because of long
Decanoate PO 0.25 mg eutic effects psychotic reactions: Parkinsonian half-life, therapeutic effects are
b.i.d. or t.i.d. - of dopamine and disorders symptoms, dystonia, slow to develop in early therapy
Brand Name: antipsychotic increases its including: akathisia, tardive or when established dosing
Haldol, Severe turnover rate schizophrenia, dyskinesia (after long- regimen is changed.
Peridol Psychosis manic states, term use); insomnia, Therapeutic window effect
adult: PO 35 drug-induced restlessness, anxiety, (point at which increased dose
mg b.i.d. or psychoses euphoria, agitation, or concentration actually
t.i.d., may need drowsiness, mental decreases therapeutic
up to 100 mg/d Useful in depression, lethargy, response) may occur after long
managing fatigue, weakness, period of high doses. Close
aggressive or tremor, ataxia, headache, observation is imperative when
agitated confusion, vertigo; doses are changed.
patients. neuroleptic malignant Target symptoms expected
syndrome, hyperthermia, to decrease with successful
grand mal seizures, haloperidol treatment include
exacerbation of psychotic hallucinations, insomnia,
symptoms. hostility, agitation, and
delusions.
CV:Tachycardia, ECG Monitor patients mental
changes, hypotension, status daily.
hypertension (with Monitor for neuroleptic
overdosage). malignant syndrome (NMS) ,
especially in those with
Endocrine:Menstrual hypertension or taking lithium.
irregularities, Symptoms of NMS can appear
galactorrhea, lactation, suddenly after initiation of
gynecomastia, impotence, therapy or after months or
increased libido, years of taking neuroleptic
DRUG STUDY BSN III Center for Behavioral Sciences
Name of Drug Dose/Route Classification Mechanism of Indication Side Effect Nursing Responsibility
Action
Generic name: Mania Antimanic alters sodium tra indicated in the Monitor response to drug.
Lithium adult: PO nsport in nerve treatment of CNS:Dizziness, Usual lag of 12 wk precedes
Carbonate Loading Dose and muscle cells manic episodes headache, lethargy, response to lithium therapy.
600 mg t.i.d. or and inhibits of Bipolar drowsiness, fatigue, Keep physician informed of
Brand Name: 900 mg release of Disorder. slurred speech, progress.
Eskalith, sustained- norepinephrine Bipolar psychomotor retardation, Monitor lithium level:
Eskalith CR, release b.i.d. or and dopamine Disorder, Manic giddiness, incontinence, Generally dosage regimen is
Lithane, 30 mL (48 mEq) but not (DSM-III) is restlessness, seizures, designed to maintain serum
Lithobid, of solution t.i.d. serotonin. equivalent to confusion, blackout spells, lithium levels of 1.01.5 mEq/L
Lithonate, Manic disorientation, recent in acute mania and 0.61.6
Lithotabs PO Depressive memory loss, stupor, mEq/L during maintenance
Maintenance illness coma, EEG changes. treatment; blood sample to
Dose CV:Arrhythmias, determine serum lithium level is
300 mg t.i.d. or indicated as a hypotension, vasculitis, drawn prior to next dose (812
q.i.d. or 1520 maintenance peripheral circulatory h after last dose) when lithium
mL (2432 treatment for collapse, ECG changes. level is fairly stable.
mEq) solution in individuals with SpecSenses:Impaired Monitor for S&S of lithium
24 divided a diagnosis of vision, transient toxicity, often when lithium
doses (max: 2.4 Bipolar scotomas, tinnitus. levels are 1.52.0 mEq/L (e.g.,
g/d) Disorder. Endocrine:Diffuse thyroid vomiting, diarrhea, lack of
child:PO 15 enlargement, coordination, drowsiness,
60 mg/kg/d in hypothyroidism, muscular weakness, slurred
DRUG STUDY BSN III Center for Behavioral Sciences
Name of Drug Dose/Route Classification Mechanism of Indication Side Effect Nursing Responsibility
Action
DRUG STUDY BSN III Center for Behavioral Sciences
Generic Name: Individualize antiepileptic Mechanism of Epilepsy, acute -Assess for seizures.
Carbamazepine dosage; a low action not mania: Mild, mostly transient and -Monitor liver function tests and
initial dosage understood; anti maintenance of dose dependent. urine function test.
Brand Name: with gradual epileptic activity bipolar affective Dizziness, ataxia, allergic -Caution patient to avoid activities
Tegretol increase is may be related disorders. skin reactions, that require alertness.
advised. to its ability to Alcohol leukopenia, vomiting, -Advise patient to use sunscreen to
inhibit withdrawal accommodation prevent photosensitivity.
PO polysynaptic disorder. disorders. Diplopia, liver -Advise patient not to discontinue
responses and enzyme elevations, SLE- medication quickly after long term
block post- like syndromes: use.
tetanic potentiati peripheral neuritis, -Teach patient to report immediately
on. Drug is hallucinations, agitation, to physician if with following
chemically depression. reactions: chills, rash, light-colored
related to the stools, drak urine, yellowing of
TCAs. skin/eyes, abdominal pain, sore
throat, mouth ulcers, bruising,
blurred vision, dizziness.