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Calculation of sample size for a Study using the Larry Connors method.

Data on which the calculation will be based:


Study Assumptions Made by investigator
Characteristic
Type of study Determining the level of ovarian volume antral follicular count and
BMI at which women with polycystic ovaries ovulate in response to a
standardized dose of tmoxifen.
Data sets study observations in Prospective and observational
Variable Standardized dose of taxoxifen
Design of sample the sample size of patients required can be calculated according to the
size following formula.
Formula

Description: n = required sample size


t = confidence level at 95% (standard value of 1.96)
p = estimated measurements
m = margin of error at 5% (standard value of 0.05)
Calculation of sample size (N):

Sample size:
The sample size must be at least 80 patients in this study.

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