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FUNCTIONS ZINCOSOMES
It is absolutely required for normal ZnT going IN to the zincosomes
spermatogenenesis, fetal growth, and embryonic ZIP going OUT of the zincosomes
development (Zn Dwarfism)
Prevents prostatic CA (males) METALLOTHIONEIN
Boost immune system (stimulates leukocytes) Binding CHON for ZN and Cu
Boost brain activity (adds a little intelligence; a special binding protein that regulates the
because intelligence is more of genetics) amount of zinc that is released in the blood
Synthesis and action of insulin (like Chromium)
Stabilizes membrane structure by preventing lipid
peroxidation and reducing free radical formation If body does NOT
If body NEEDS zinc
(ANTIOXIDANT) need zinc
Component of GUSTIN, a salivary protein that has
an ability to increase appetite
Zinc and PMS (Zn PMS)
Involved in the synthesis and stabilization of Zinc is incorporated Zinc is incorporated
into intestinal into intestinal
proteins, DNA and RNA and plays a structural role metallothionein metallothionein
in ribosomes and membranes.
Necessary for the binding of steroid hormone
receptors and several other transcription factors
to DNA (steroid synthesis) Zinc SLOUGHED OFF Zinc is transported
As Co-factors of enzymes: with intestinal cells into BLOOD STREAM
o PT
Peptidases
Thymidine Kinase PROSTATE GLAND:
o CLAS
Carbonic Anhydrase
Lactate DH
Alkaline Phosphate
Superoxide Dismutase
ZINC HOMEOSTASIS
3. ORGANIFICATION
o Iodine will bind to tyrosine
o Aka IODINIFICATION
4. COUPLING MECHANISM
o MIT (MONOiodotyrosine) 1
o DIT (DIiodotyrosine) - 2
MIT + DIT T3
DIT + DIT T4
5. PROTEOLYSIS
6. DEIODINATION