Thunyaporn Koprasopsuk

Vitamin a

Purpose
Vitamin A is a fat-soluble vitamin that comes from two sources: preformed retinoid
and provitamin carotenoids. Retinoid are found in animal sources such as liver,
kidney, eggs, and dairy products. Carotenoids are found in plants such as dark or
yellow vegetables and carrots. Research suggests that vitamin A may reduce death
from measles, prevent some types of cancer, aid in growth and development, and
improve immune function.

Application
Vitamin A has many benefits to human such as treatment, supplement, and cosmetic.
In Africa there are a big problem about polio, so PEI provided a platform for
integrated delivery of vitamin A in the African Region. The result is the percent of
polio decrease. Vitamin a or retinol is also recommend their patient to use when the
skin show the sigh of aging or clogging pore. These retinol creams will help smooth
of fine line and small pimples. Vitamin a is keys for good vision, which can be found
in many vegetable include carrot.
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Chemical and
Physical Properties

Property Name Property Value

Molecular Weight 286.459 g/mol

Hydrogen Bond Donor Count 1

Hydrogen Bond Acceptor Count 1

Rotatable Bond Count 5

Complexity 496

Topological Polar Surface Area 20.2 A^2

Monoisotopic Mass 286.23 g/mol

Exact Mass 286.23 g/mol

XLogP3 5.7

Compound Is Canonicalized true

Formal Charge 0

Heavy Atom Count 21

Defined Atom Stereocenter Count 0

Undefined Atom Stereocenter Count 0

Defined Bond Stereocenter Count 4

Undefined Bond Stereocenter Count 0

Isotope Atom Count 0

Covalently-Bonded Unit Count 1

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Physical Description
PHYSICAL DESCRIPTION: Yellow crystals or orange solid. Practically
water insoluble.

Color
Solvated crystals from polar solvents, such as methanol or ethyl formate

Boiling Point
279 to 280 F at 1e-06 mm Hg

Melting Point
144 to 147 F
63.5 C

Solubility
Practically insoluble
Water Solubility
0.671 mg/L
Practically insoluble in water or glycerol; soluble in absolute alcohol, methanol,
chloroform, ether, fats and oils

Vapor Pressure
7.5X10-8 mm Hg at 25 deg C /Estimated/

Bibliography

Retinol. (n.d.). Retrieved May 23, 2017, from

https://pubchem.ncbi.nlm.nih.gov/compound/retinol#section=Top
 Thunyaporn Koprasopsuk

Vitamin A (retinol) Background. (2013, November 01).

Retrieved May 23, 2017, from
http://www.mayoclinic.org/drugs-supplements/vitamin-
a/background/hrb-20060201

Elizabeth Tangel Chehab, 2016, Experience of integrating vitamin A

supplementation into polio campaigns in the African Region,
Vaccine, Volume 34, Issue 43, Pages 51995202,
http://www.sciencedirect.com/science/journal/0264410X