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Estimasi GFR
- The MDRD Equation
GFR (mL/min/1.73 m2) = 175 (Scr)-1.154 (Age)-0.203 (0.742 if female) (1.212 if African
American)
- This CKD-EPI equation
GFR = 141 min (Scr /, 1) max(Scr /, 1)-1.209 0.993Age 1.018 [if female] 1.159 [if
black]
where:
Scr is serum creatinine in mg/dL,
is 0.7 for females and 0.9 for males,
is -0.329 for females and -0.411 for males,
min indicates the minimum of Scr / or 1, and
max indicates the maximum of Scr / or 1.
2. Stage CKD
Albumin 4+ menandakan adanya kidney damage
GFR 30 (GFR 30-69 Moderate decrease of GFR)
Sehingga jika abnormalitas lebih dari 3 bulan termasuk Stage 3 CKD
3. Etiologi karena adanya risk factor seperti diabetes dan hipertensi yang tidak dikontrol
dengan baik menyebabkan injury berulang pada struktur ginjal sehingga menyebabkan
chronic kidney disease
4. Strategy to deal CKD
Setelah diagnosis CKD ditegakkan, dilakuan staging berdasarkan kidney damage dan
penurunan GFR untuk menentukan evalusi dan manajemen selanjutnya
Pada kasus karena sudah terjadi penurunan GFR makan dilakukan evaluasi komplikasi
pencegah dan terapi komplikasi dan persiapan replacemen.
Target : with a target HbA1c of 7%, namun bisa lebih tinggi tergantung dengan
adanya korbiditas, terbatas life expentacy dan resiko hypoglikemia
For patients who are relatively young (50 years) and have no other significant
comorbid conditions, we suggest using an A1C goal of 7 to 7.5, rather than higher
values (Grade 2C).
For older patients (ie, >50 years) who have multiple comorbid conditions, we suggest
using an A1C goal of 7.5 to 8, rather than lower values (Grade 2C
7. Other comorbidity should be anticipated and lab test should be done to confirm