Sevial, Jasper Abigail F.

March 13, 2009

B. S. P. T. 4 Pharmacology
Drug Index – Gastrointestinal Dr. Inciong

GENERIC NAME BRAND INDICATION MODE ADVERSE REACTION

NAME OF
ACTION
Antacids and Antiulcerants
Dried Al (OH)3 Alu-Tab 3M Uncomplicated peptic ulcer & Constipation.
gel gastric hyperacidity;
phosphate binding in renal
dysfunction.
Cimetidine Ciclem Treatment of gastric & Diarrhea, muscle pain,
duodenal ulcer. Inhibition of dizziness & skin rash.
gastric secretion.
Ranitidine Danitin Duodenal ulcer, active & Diarrhea, constipation;
benign gastric ulcer, peptic dizziness, tiredness,
ulcer, reflux esophagus, headache; rash. Rarely,
Zollinger-Ellison syndrome. allergic reactions, arthralgia,
myalgia, blood disorders,
hepatoxicity & pancreatitis.
Sucralfate Iselpin Duodenal & gastric ulcers, Constipation, diarrhea,
chronic gastritis. nausea, GI discomfort,
indigestion; dry mouth;
rash, pruritus; back pain;
dizziness, drowsiness &
vertigo.
Omeprazole Lopep Peptic ulcer. Used in conditions Nausea, diarrhea,
Zynova where inhibition of gastric acid constipation, flatulence, skin
 secretion may be beneficial, rash, headache.
including acid aspiration
syndrome, GERD & Zollinger-
Ellison syndrome.
GIT Regulators, Antiflatulents & Anti-inflammatories
Domperidone Dompenyl Dyspeptic symptom complex Shock. Gynecomastia,
associated w/ delayed gastric galactorrhea, hysterorrhea;
emptying, GERD & anorexia, catharsis,
esophagitis. Symptomatic constipation,celialgia, dipsia,
relief of acute nausea & vomiting. Extrapyramidal,
vomiting. Treatment of nausea circulatory & dermatologoc
& vomiting caused by effects.
levodopa or bromocriptine
administration in Parkinson’s
disease.
Itopride HCl Ganaton GI symptoms of functional, Diarrhea, headache,
non-ulcer dyspepsia (chronic abdominal pain.
gastritis) i. e. feeling of
abdominal bloatedness, upper
abdominal pain, heartburn,
nausea & vomiting.
Tegaserod Zelnorm* Treatment of abdominal pain & The overall incidence of
discomfort, bloating & altered adverse events in clinical
bowel function in patients w/ trials was comparable w/
irritable bowel syndrome that of a placebo, w/ the
whose main symptoms are exemption of diarrhea.
pain or discomfort &
constipation. Treatment of
straining, hard or lumpy stools
& infrequent defecation in
patients w/ chronic
constipation.
 Antispasmodics
Hyoscine-N- Amucin Management of motion Constipation, dysuria,
butylbromide sickness & other forms of eruption, tachycardia,
nausea & vomiting. Also used mydriasis, vomiting, rubor.
as premedicant in anesth & to
produce cyclopedia &
mydriasis & in condition
associated w/ visceral spasms.
Dicycloverine Bentyl Treatment of functional GIT Dry mouth, thirst, dizziness.
HCl Duncan conditions involving smooth Rarely, fatigue, sedation,
muscle spasms e. g. irritable blurred vision, rash,
colon (mucus colitis, spastic anorexia. GI disturbances,
colon, irritable bowel headache, psychotic
syndrome,) & spastic symptoms, dysuria,
constipation. Adjunctive constipation & headache.
therapy in organic GIT
conditions to relieve
associated smooth muscle
spasm e. g. colitis,
diverticulitis, regional enteritis,
gastritis & peptic ulcer.
Drotaverine HCl Deolin Relief of pain caused by Rarely, GI disturbances,
Unison smooth muscle spasm in GIT. headache, vertigo &
orthostatic hypotension.
Pinaverium Br Eldicet Symptomatic treatment of Mild GI disturbance, isolated
pain, transit disorders & cases of undesirable
intestinal discomfort related to cutaneous effects, some
functional intestinal being of allergic etiology.
disturbances; symptomatic
treatment of pain related to
functional disturbances of the
 biliary tract; preparation for
barium enema.
Fenoverine Spasmopriv GI spasm due to irritable Myalgias, reversible
bowel syndrome & biliary rhabdomyolysis. Gastric
dyskinesia. upset.
Antidiarrheals
Loperamide HCl Bryper Acute and chronic diarrhea; Abdominal pain, GI
management of ileostomy. disturbances e. g.
megacolon, dry mouth,
dizziness, fatigue;
hypersensitivity reactions e.
g. skin rashes.
Laxatives, Purgatives
Bisacodyl Bisalax Constipation. Irritation; repeated use may
Cipla cause proctitis or sloughing
of the epithelium.
Cholagogues, Cholelitholytics & Hepatic Protectors
Lactulose Duphalac Hyperammonemia. Flatulence, diarrhea.
Prophylactic treatment of
patients who have suffered
from acute episodes of PSE,
who have confirmed cirrhosis
likely to result in PSE.
Anorectal Preparations
Troxerutin Venoruton Relief of edema & related Mild GI disturbances,
Forte symptoms of chronic venous headache, flushing, skin
insufficiency. Varicose rashes.
dermatitis. Venous ulcers.
Hemorrhoids. Adjuvant in
diabetic retinopathy.
Antiemetics
Metoclopramide Biclomet Relief of nausea & vomiting Sedation, restlessness,
HCl Biomedis associated w/ radiation lassitude, fatigue, diarrhea,
therapy, malignant disease, insomnia, headache,
labor, infectious diseases & dizziness, nausea,
uremia. Control of post-op extrapyramidal effects &
vomiting & assist in intestinal tardive dyskinesia.
intubation.