Biological Manipulation (freak)

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Biological Manipulation (freak) The ability to turn another being or yourself into
a freak/monster.

The saddest freak transformation story was when Darkseid (DC) turned the son of
Lightning Lad and Saturn Girl into Validus (Legion of Super-Heroes Annual V3 #2).

Mister Hyde (Marvel) is a scientist that can turn into a monster (Official Handbook of
the Marvel Universe V1 #7).
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Monster Girl (Image) can turn into a monster and back at will (The Official Handbook
of the Invincible Universe #2).

Turning a hero into a freak is so much fun, BWAHAHA (Action Comics V1 #284,
Aquaman V1 #21, Batman V1 #162, Brave and Bold V1 #68, Challengers of the
Unknown V1 #50, Jimmy Olsen V1 #53, Jimmy Olsen V1 #59, Lois Lane V1 #66, Rip
Hunter Time Master V1 #28).
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 Biological Manipulation (freak)
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The Falange is a former officer of the Spanish army that has been transformed
into a monster by an experimental combat gas and is part of The Chimera
Brigade (Titan).
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Vurk's normal form is that of an alien monster in the Ultraverse (1993 SkyBox
Ultraverse).

The American Kaiju (Marvel) is Godzilla in the service of the US government (Avengers
Standoff).
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Cypher (Marvel) - New Mutants Forever #5

Ghoul - Field Guide to Cthulhu Monsters

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Meenlock - TSR 2158 Monstrous Compendium Annual Volume 2

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In Journey into Mystery V1 #79, a man decides to become "The Midnight Monster" but
comes to an ironic end.