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PowerPoint Lecture Slide Presentation

by Patty Bostwick-Taylor,
Florence-Darlington Technical College

The Human Body:


An Orientation

1 PART A

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The Human BodyAn Orientation
Anatomy
Study of the structure and shape of the body
and its parts
Physiology
Study of how the body and its parts work or
function

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AnatomyLevels of Study
Gross anatomy
Large structures
Easily observable

Anatomy (Greek word)


Cut (tomy) apart (ana)

Figure 14.1

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AnatomyLevels of Study
Microscopic Anatomy
Very small
structures
Can only be
viewed with
a microscope

Figure 14.4cd

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Levels of Structural Organization

Smooth muscle cell


Molecules

Cellular level Atoms


Cells are made up of
molecules

Chemical level
Atoms combine to
form molecules

Smooth
muscle
Tissue level tissue
Tissues consist of
similar types of cells

Epithelial
tissue
Smooth
muscle Blood
tissue vessel
(organ) Cardio- Organismal level
Connective vascular Human organisms
tissue system are made up of many
organ systems
Organ level
Organs are made up
of different types Organ system level
of tissues Organ systems consist of different
organs that work together closely
Figure 1.1

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Levels of Structural Organization

Molecules

Atoms

Chemical level
Atoms combine to
form molecules

Figure 1.1, step 1

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Levels of Structural Organization

Smooth muscle cell


Molecules

Cellular level Atoms


Cells are made up of
molecules

Chemical level
Atoms combine to
form molecules

Figure 1.1, step 2

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Levels of Structural Organization

Smooth muscle cell


Molecules

Cellular level Atoms


Cells are made up of
molecules

Chemical level
Atoms combine to
form molecules

Smooth
muscle
Tissue level tissue
Tissues consist of
similar types of cells

Figure 1.1, step 3

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Levels of Structural Organization

Smooth muscle cell


Molecules

Cellular level Atoms


Cells are made up of
molecules

Chemical level
Atoms combine to
form molecules

Smooth
muscle
Tissue level tissue
Tissues consist of
similar types of cells

Epithelial
tissue
Smooth
muscle Blood
tissue vessel
(organ)
Connective
tissue
Organ level
Organs are made up
of different types
of tissues
Figure 1.1, step 4

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Levels of Structural Organization

Smooth muscle cell


Molecules

Cellular level Atoms


Cells are made up of
molecules

Chemical level
Atoms combine to
form molecules

Smooth
muscle
Tissue level tissue
Tissues consist of
similar types of cells

Epithelial
tissue
Smooth
muscle Blood
tissue vessel
(organ) Cardio-
Connective vascular
tissue system
Organ level
Organs are made up
of different types Organ system level
of tissues Organ systems consist of different
organs that work together closely
Figure 1.1, step 5

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Levels of Structural Organization

Smooth muscle cell


Molecules

Cellular level Atoms


Cells are made up of
molecules

Chemical level
Atoms combine to
form molecules

Smooth
muscle
Tissue level tissue
Tissues consist of
similar types of cells

Epithelial
tissue
Smooth
muscle Blood
tissue vessel
(organ) Cardio- Organismal level
Connective vascular Human organisms
tissue system are made up of many
organ systems
Organ level
Organs are made up
of different types Organ system level
of tissues Organ systems consist of different
organs that work together closely
Figure 1.1, step 6

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Organ System Overview
Integumentary (, )
Forms the external body
covering
Protects deeper tissue from
injury
Helps regulate body
temperature
Location of cutaneous
nerve receptors

Figure 1.2a

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Organ System Overview
Skeletal
Protects and supports
body organs
Provides muscle
attachment for movement
Site of blood cell
formation
Stores minerals

Figure 1.2b

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Organ System Overview
Muscular
Produces movement
Maintains posture
Produces heat

Figure 1.2c

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Organ System Overview
Nervous
Fast-acting control
system
Responds to internal and
external change
Activates muscles and
glands

Figure 1.2d

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Organ System Overview
Endocrine

Secretes regulatory
hormones
Growth
Reproduction
Metabolism

Figure 1.2e

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Organ System Overview

Cardiovascular
Transports materials in body
via blood pumped by heart
Oxygen
Carbon dioxide
Nutrients
Wastes

Figure 1.2f

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Organ System Overview

Lymphatic
Returns fluids to blood
vessels
Cleanses the blood
Involved in immunity

Figure 1.2g

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Organ System Overview

Respiratory
Keeps blood supplied with ['frks]
[lrks]

oxygen [treki]

[br:ks]
Removes carbon dioxide

Figure 1.2h

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Organ System Overview

Digestive
Breaks down food
[asfs]

Allows for nutrient


absorption into blood
Eliminates indigestible
material

[ens]

Figure 1.2i

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Organ System Overview

Urinary
Eliminates nitrogenous
wastes
Maintains acid-base [j'ri:t]

balance
Regulates water and
electrolytes
[j'ri:r]

Figure 1.2j

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Organ System Overview

Reproductive
Produces
offspring

[smnl vskl]


[vsdfrnz

[vdan]
[skrotm]

Figure 1.2kl

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The Language of Anatomy

Special terminology is used to prevent


misunderstanding
Exact terms are used for
Position
Direction
Regions
Structures
Anatomical position:
Body is erect, feet together, arms hanging at
the sides with the palms facing forward.

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Directional Terms

Table 1.1 (1 of 3)

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Directional Terms

[mi:dil],

[pr:ksml]

Table 1.1 (2 of 3)

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Directional Terms

Table 1.1 (3 of 3)

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Body Planes and Sections

A sagittal section divides the body (or organ) into


left and right parts
A median, or midsagittal, section divides the body
(or organ) into equal left and right parts
A frontal section divides the body (or organ) into
anterior and posterior parts
A transverse, or cross, section divides the body
(or organ) into superior and inferior parts

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Body Planes and Sections

Figure 1.6

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Regional Terms

Anterior body landmarks


[sflk]

[:rbtl]

['bkl]
[lm]
['krmrl] ,

, [rsk] ['deltd],
['brekrl],

[nt'kjbtl] ,

[bd:mnl]
[nteb'rkjl],

, [m'blkl]
[k:rpl],

, ['gwnl]
['kksl] ,
['femrl] ,
,[pjubk]
[p'tel],

['krrl],

['fbjlr],
[rks ]
[t:rsl] ([kl] ),
[bdmn]

['d:sm]

[ntri(r)] / [vntrl] /
Figure 1.5a

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Regional Terms

Posterior body landmarks


[k'sptl],

['skpjl],

[vtbrl],

[lmb, -br],

['sekrl],

[glu:'ti:l],

, [pp'ltrl]

, ['sjrl]

, [kl'kenrl]

, [plnt]

[d:rsl] ,
Figure 1.5b

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Body Cavities

Dorsal body cavity,


Cranial cavity houses the brain
Spinal cavity houses the spinal cord
Ventral body cavity,
Thoracic cavity houses heart, lungs and
others
Abdominopelvic cavity houses digestive
system and most urinary system organs

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Body Cavities

Figure 1.7

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Abdominopelvic Quadrants ['kwdrnts]

Figure 1.8a

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Abdominopelvic Regions

[epi'gstrk] ,
[hapk:ndrik],
['lk],

Figure 1.8b

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Abdominopelvic Major Organs

[dafrm],

Figure 1.8c

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


PowerPoint Lecture Slide Presentation
by Patty Bostwick-Taylor,
Florence-Darlington Technical College

Cells and
Tissues

1 PART A

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Cells and Tissues
Carry out all chemical activities needed to sustain
life
Cells are the building blocks of all living things
Tissues are groups of cells that are similar in
structure and function

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Anatomy of the Cell
Cells are not all the same
All cells share general structures
All cells have three main regions
Nucleus
Cytoplasm
Plasma membrane

Figure 3.1a

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The Nucleus
Control center of the cell
Contains genetic material (DNA)
Three regions
Nuclear envelope (membrane)
Nucleolus

Chromatin

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The Nucleus

Figure 3.1b

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The Nucleus
Nuclear envelope (membrane)
Barrier of the nucleus
Consists of a double membrane
Contains nuclear pores that allow for
exchange of material with the rest of the cell

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The Nucleus
Nucleoli
Nucleus contains one or more nucleoli
Sites of ribosome assembly
Ribosomes migrate into the cytoplasm
through nuclear pores

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The Nucleus
Chromatin
Composed of DNA and protein
Present when the cell is not dividing
Scattered throughout the nucleus
Condenses to form chromosomes when the
cell divides

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Plasma Membrane
Barrier for cell contents
Double phospholipid layer
Hydrophilic heads
Hydrophobic tails
Also contains proteins, cholesterol, and
glycoproteins

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Plasma Membrane

Figure 3.2

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Plasma Membrane Specializations
Microvilli
Finger-like projections that increase surface
area for absorption

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Plasma Membrane Specializations
Membrane junctions
Tight junctions
Impermeable junctions
Bind cells together into leakproof sheets
Desmosomes
Anchoring junctions that prevent cells
from being pulled apart
Gap junctions
Allow communication between cells

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Plasma Membrane Specializations

Figure 3.3

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Cytoplasm
Cytoplasm is the material outside the nucleus and
inside the plasma membrane

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Cytoplasm
Contains three major elements
Cytosol
Fluid that suspends other elements
Organelles
Metabolic machinery of the cell
Little organs that perform functions for
the cell
Inclusions
Chemical substances such as stored
nutrients or cell products

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Cytoplasmic Organelles

Figure 3.4

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Cytoplasmic Organelles
Mitochondria
Powerhouses of the cell
Change shape continuously
Carry out reactions where oxygen is used to
break down food
Provides ATP for cellular energy

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Cytoplasmic Organelles
Ribosomes
Made of protein and RNA
Sites of protein synthesis
Found at two locations
Free in the cytoplasm
As part of the rough endoplasmic
reticulum

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Cytoplasmic Organelles
Endoplasmic reticulum (ER)
Fluid-filled tubules for carrying substances
Two types of ER
Rough endoplasmic reticulum
Studded with ribosomes
Synthesizes proteins
Smooth endoplasmic reticulum
Functions in lipid metabolism and
detoxification of drugs and pesticides

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Rough Endoplasmic Reticulum
As the protein is synthesized
Ribosome on the ribosome, it migrates
into the rough ER cistern.
mRNA

Rough ER
In the cistern, the protein folds
into its functional shape. Short
sugar chains may be attached
to the protein (forming a
glycoprotein).
Protein

The protein is packaged in a


Transport tiny membranous sac called a
vesicle buds off transport vesicle.

The transport vesicle buds from


the rough ER and travels to the
Golgi apparatus for further
processing or goes directly to
the plasma membrane where its
contents are secreted.
Protein inside
transport vesicle

Figure 3.5

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough Endoplasmic Reticulum
As the protein is synthesized
Ribosome on the ribosome, it migrates
into the rough ER cistern.
mRNA

Rough ER

Protein

Figure 3.5, step 1

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough Endoplasmic Reticulum
As the protein is synthesized
Ribosome on the ribosome, it migrates
into the rough ER cistern.
mRNA

Rough ER
In the cistern, the protein folds
into its functional shape. Short
sugar chains may be attached
to the protein (forming a
glycoprotein).
Protein

Figure 3.5, step 2

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough Endoplasmic Reticulum
As the protein is synthesized
Ribosome on the ribosome, it migrates
into the rough ER cistern.
mRNA

Rough ER
In the cistern, the protein folds
into its functional shape. Short
sugar chains may be attached
to the protein (forming a
glycoprotein).
Protein

The protein is packaged in a


Transport tiny membranous sac called a
vesicle buds off transport vesicle.

Figure 3.5, step 3

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough Endoplasmic Reticulum
As the protein is synthesized
Ribosome on the ribosome, it migrates
into the rough ER cistern.
mRNA

Rough ER
In the cistern, the protein folds
into its functional shape. Short
sugar chains may be attached
to the protein (forming a
glycoprotein).
Protein

The protein is packaged in a


Transport tiny membranous sac called a
vesicle buds off transport vesicle.

The transport vesicle buds from


the rough ER and travels to the
Golgi apparatus for further
processing or goes directly to
the plasma membrane where its
contents are secreted.
Protein inside
transport vesicle

Figure 3.5, step 4

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Cytoplasmic Organelles
Golgi apparatus
Modifies and packages proteins
Produces different types of packages
Secretory vesicles
Cell membrane components
Lysosomes

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Rough ER Proteins in cisterna

Cisterna Membrane Lysosome fuses with


ingested substances

Transport
vesicle
Golgi vesicle containing
digestive enzymes
becomes a lysosome
Pathway 3

Golgi Pathway 2
apparatus
Secretory vesicles
Pathway 1 Golgi vesicle containing
Proteins membrane components
Golgi vesicle containing fuses with the plasma
proteins to be secreted membrane
becomes a secretory Secretion by
vesicle exocytosis Plasma membrane

Extracellular fluid
Figure 3.6

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Rough ER Proteins in cisterna

Cisterna Membrane

Golgi
apparatus

Plasma membrane

Extracellular fluid
Figure 3.6, step 1

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Rough ER Proteins in cisterna

Cisterna Membrane

Transport
vesicle

Golgi
apparatus

Pathway 1

Plasma membrane

Extracellular fluid
Figure 3.6, step 2

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane

Transport
vesicle

Golgi
apparatus

Pathway 1

Plasma membrane

Extracellular fluid
Figure 3.6, step 3

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane

Transport
vesicle

Golgi
apparatus
Secretory vesicle
Pathway 1

Golgi vesicle containing


proteins to be secreted
becomes a secretory
vesicle Plasma membrane

Extracellular fluid
Figure 3.6, step 4

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane

Transport
vesicle

Golgi
apparatus
Secretory vesicles
Pathway 1
Proteins
Golgi vesicle containing
proteins to be secreted
becomes a secretory Secretion by
vesicle exocytosis Plasma membrane

Extracellular fluid
Figure 3.6, step 5

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane

Transport
vesicle

Golgi Pathway 2
apparatus

Plasma membrane

Extracellular fluid
Figure 3.6, step 6

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane

Transport
vesicle

Golgi Pathway 2
apparatus

Plasma membrane

Extracellular fluid
Figure 3.6, step 7

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane

Transport
vesicle

Golgi Pathway 2
apparatus

Golgi vesicle containing


membrane components
fuses with the plasma
membrane

Plasma membrane

Extracellular fluid
Figure 3.6, step 8

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane

Transport
vesicle

Pathway 3

Golgi
apparatus

Plasma membrane

Extracellular fluid
Figure 3.6, step 9

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane

Transport
vesicle
Golgi vesicle containing
digestive enzymes
becomes a lysosome
Pathway 3

Golgi
apparatus

Plasma membrane

Extracellular fluid
Figure 3.6, step 10

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane Lysosome fuses with


ingested substances

Transport
vesicle
Golgi vesicle containing
digestive enzymes
becomes a lysosome
Pathway 3

Golgi
apparatus

Plasma membrane

Extracellular fluid
Figure 3.6, step 11

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Rough ER Proteins in cisterna

Cisterna Membrane Lysosome fuses with


ingested substances

Transport
vesicle
Golgi vesicle containing
digestive enzymes
becomes a lysosome
Pathway 3

Golgi Pathway 2
apparatus
Secretory vesicles
Pathway 1 Golgi vesicle containing
Proteins membrane components
Golgi vesicle containing fuses with the plasma
proteins to be secreted membrane
becomes a secretory Secretion by
vesicle exocytosis Plasma membrane

Extracellular fluid
Figure 3.6, step 12

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings


Cytoplasmic Organelles
Lysosomes
Contain enzymes that digest worn-out or
nonusable materials within the cell

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Cytoplasmic Organelles
Peroxisomes
Membranous sacs of oxidase enzymes
Detoxify harmful substances such as
alcohol and formaldehyde
Break down free radicals (highly reactive
chemicals)
Replicate by pinching in half

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Cytoplasmic Organelles
Cytoskeleton
Network of protein structures that extend
throughout the cytoplasm
Provides the cell with an internal framework

Figure 3.7a

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Cytoplasmic Organelles
Cytoskeleton
Three different types of
elements
Microfilaments
(smallest)
Intermediate
filaments
Microtubules
(largest)

Figure 3.7bd

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Cytoplasmic Organelles
Centrioles
Rod-shaped bodies made of microtubules
Direct the formation of mitotic spindle during
cell division

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Cellular Projections
Not found in all cells
Used for movement
Cilia move materials across the cell surface
Located in the respiratory system to move
mucus
Flagella propel the cell
The only flagellated cell in the human
body is sperm

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Cell Diversity

Figure 3.8a

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Cell Diversity

Figure 3.8b

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Cell Diversity

Figure 3.8c

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Cell Diversity

Figure 3.8d

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Cell Diversity

Figure 3.8e

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Cell Diversity

Figure 3.8f

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Cell Diversity

Figure 3.8g

Copyright 2009 Pearson Education, Inc., publishing as Benjamin Cummings

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